BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0126.0023.p (320 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9KR19.1 A9KR19_CLOPH Adenosine deaminase EC=3.5.4.4 377 e-102 C4ZBB0.1 C4ZBB0_9FIRM Adenosine deaminase 231 6e-59 B9Y730.1 B9Y730_9FIRM Putative uncharacterized protein 226 2e-57 Q73RA3.1 Q73RA3_TREDE Adenosine/AMP deaminase family protein 155 5e-36 B2S1Z3.1 ADD_TREPS Adenosine deaminase EC=3.5.4.4 149 4e-34 >A9KR19.1 A9KR19_CLOPH Adenosine deaminase EC=3.5.4.4 Length = 315 Score = 377 bits (967), Expect = e-102, Method: Compositional matrix adjust. Identities = 180/310 (58%), Positives = 226/310 (72%), Gaps = 7/310 (2%) Query: 14 FMDSLINDSLTNLQTIPKSDLHNHAGRGGTIQYIGEWANIQIQPPSKPFQSLHGMQKWFD 73 F L N++L L +IPKSDLHNHAG GG + YI NI+I P F+S+ M WF Sbjct: 5 FKTCLQNNNLLELSSIPKSDLHNHAGCGGNVNYIASQTNIKIDQPPAVFESMFHMHSWFT 64 Query: 74 EHIKCHCPGIHGYLKRIEASFVQAAGDHIEKLALSFGIDEIDSLGGMEH--FTRIIDDLH 131 ++IK HC YLKR+EA+FVQA D+I LA+S DE + +GGM+ F + ++ Sbjct: 65 DNIKVHCT----YLKRLEAAFVQAYDDNIHVLAMSLETDEANKIGGMDLGLFIQTMNTFK 120 Query: 132 RSFAPKTRFLPELALDRAC-DIDEVYGRMDELLAFRWFRSIDICGDELAQPIACFKSIYR 190 + AP T FLPEL +RAC D+D Y R+DE+L+F WF+S+DIC DE AQPI FK IYR Sbjct: 121 QRLAPSTIFLPELTFNRACCDVDNTYSRLDEILSFHWFKSLDICNDEFAQPIKNFKKIYR 180 Query: 191 AANSAGLILKAHVGEFGAADDVREAVEELGLQEVHHGIAAARSPQIMRWLSDHNIQLNVC 250 A +GL LKAHVGEFG A+DV EAVEEL L EVHHGIAA SP IM+WL+D+ +QLN+C Sbjct: 181 KAKDSGLRLKAHVGEFGTANDVMEAVEELELDEVHHGIAAVTSPLIMKWLADNRVQLNIC 240 Query: 251 PTSNIMLGVAENYGRHPIRKLYDFGIPVTINTDDLLIFNQSVSREYMNLYKSGSITAEEL 310 P+SN+MLGV + Y HPIRKLYD+GIPVTINTDDLLIFNQ+VS+EY+NLY++ +T EEL Sbjct: 241 PSSNVMLGVVKGYDVHPIRKLYDYGIPVTINTDDLLIFNQTVSQEYLNLYEAKLMTVEEL 300 Query: 311 NEIRLTGLKE 320 ++IR GLKE Sbjct: 301 DDIREIGLKE 310 >C4ZBB0.1 C4ZBB0_9FIRM Adenosine deaminase Length = 315 Score = 231 bits (590), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 136/320 (42%), Positives = 184/320 (57%), Gaps = 24/320 (7%) Query: 13 AFMDSLINDSLTNLQTIPKSDLHNHAGRGGTIQYIGEWANIQIQPPSKPFQSLHGMQKWF 72 F D+L +L L+ PK+DLHNH GG ++I + +I+P + P S+ M +W Sbjct: 3 GFTDALEQRNLEELRKYPKADLHNHFVLGGNRRFIYQETRKKIEPLANPLSSMDEMNQWS 62 Query: 73 DEHIK--CHCPGIHGYLKRIEASFVQAAGDHIEKLALSFGIDEIDSLGGMEHFTRIIDDL 130 ++I + + +L I A+F QA D + L + D G E F ID+L Sbjct: 63 QKYISQDFNSTAMRKFL--IRATFQQAREDGVTVLEIG-----EDVWGLNEFFNNDIDEL 115 Query: 131 HRSF-------APKTRFLPELALDRACDIDEVYGRMDELLAFRW----FRSIDICGDELA 179 +F AP ++ L R C I +++ L++ W F SID+ GDELA Sbjct: 116 VNAFTSAQKEIAPDIELRLQIGLSRHCSI----SYLEDCLSYFWGNKNFYSIDLYGDELA 171 Query: 180 QPIACFKSIYRAANSAGLILKAHVGEFGAADDVREAVEELGLQEVHHGIAAARSPQIMRW 239 QPI FK IYR A GL LKAHVGE+G A DVR AVEEL L EV HGIAA ++R+ Sbjct: 172 QPIENFKGIYRRAKKEGLRLKAHVGEWGTAKDVRTAVEELELDEVQHGIAAVSDESVIRF 231 Query: 240 LSDHNIQLNVCPTSNIMLGVAENYGRHPIRKLYDFGIPVTINTDDLLIFNQSVSREYMNL 299 L+D+ I+LN+ PTSNI+LG + HPI KLY G+ VTIN+DD+LIF+ VS+EY+ L Sbjct: 232 LADNKIRLNITPTSNILLGRVADMSMHPIGKLYRSGVDVTINSDDVLIFDSDVSKEYLRL 291 Query: 300 YKSGSITAEELNEIRLTGLK 319 Y+ +TAEEL IR GLK Sbjct: 292 YEFQCLTAEELENIRKNGLK 311 >B9Y730.1 B9Y730_9FIRM Putative uncharacterized protein Length = 405 Score = 226 bits (576), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 127/319 (39%), Positives = 184/319 (57%), Gaps = 5/319 (1%) Query: 6 EEFSIKQA---FMDSLINDSLTNLQTIPKSDLHNHAGRGGTIQYIGEWANIQIQPPSKPF 62 EE S+ +A F +L L L+ IPK+DLHNH GG ++I E +++I+ P Sbjct: 87 EENSMNEASVLFKAALRAGDLAALRKIPKADLHNHFMLGGDREWIAERWDVRIEAIQAPL 146 Query: 63 QSLHGMQKWFDEHIKCHCPGIHGYLKRIEASFVQAAGDHIEKLALSFGIDEIDSL--GGM 120 QS+ M +W I P G L+ +EA+ QA D + L + + + G + Sbjct: 147 QSMAEMDQWSQVSINTPFPDRTGRLRLLEATLHQAVKDGVSVLEIGEDVWALKHFYHGDV 206 Query: 121 EHFTRIIDDLHRSFAPKTRFLPELALDRACDIDEVYGRMDELLAFRWFRSIDICGDELAQ 180 E+ + + AP+ ++ + R C + + ++ F S+D+ GDE AQ Sbjct: 207 ENLLASWKAVQEAAAPQIELRFQIGISRHCGVPYLMEKLAPFWDRPEFYSLDLYGDEQAQ 266 Query: 181 PIACFKSIYRAANSAGLILKAHVGEFGAADDVREAVEELGLQEVHHGIAAARSPQIMRWL 240 PI F +YR A +G +LKAHVGE+G+A DVR+AVE L L EV HGIAAA+ P +M L Sbjct: 267 PIENFIPLYRRARQSGWVLKAHVGEWGSAQDVRQAVECLDLDEVQHGIAAAQDPAVMELL 326 Query: 241 SDHNIQLNVCPTSNIMLGVAENYGRHPIRKLYDFGIPVTINTDDLLIFNQSVSREYMNLY 300 ++LN+ PTSN +LG + HPI +L GIPVTIN+DD+LIF+ VS+EY+ LY Sbjct: 327 RQKQVRLNITPTSNRLLGRVASLADHPIAQLKRAGIPVTINSDDVLIFDSDVSKEYLRLY 386 Query: 301 KSGSITAEELNEIRLTGLK 319 K+ ++TAEEL+EIR GLK Sbjct: 387 KAETLTAEELDEIRQEGLK 405 >Q73RA3.1 Q73RA3_TREDE Adenosine/AMP deaminase family protein Length = 299 Score = 155 bits (392), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 89/285 (31%), Positives = 152/285 (53%), Gaps = 1/285 (0%) Query: 30 PKSDLHNHAGRGGTIQYIGEWANIQIQPPSKPFQSLHGMQKWFDEHIKCHCPGIHGYLKR 89 PK+D HNH +WA +I + L M + ++ + C + Sbjct: 11 PKADTHNHLNLSMEYSDYKKWAGFEIPNFPRKMNGLDEMHEIIGQYTRPACTTAQHVIDL 70 Query: 90 IEASFVQAAGDHIEKLALSFGIDEIDSLG-GMEHFTRIIDDLHRSFAPKTRFLPELALDR 148 IE S + A D++ + S I I ++ F I + + + K + +PEL + + Sbjct: 71 IEMSIMTAIKDNVVCIEGSVDIGFIKQFNENLDAFLEGISGIVKKYKNKIKIIPELGISK 130 Query: 149 ACDIDEVYGRMDELLAFRWFRSIDICGDELAQPIACFKSIYRAANSAGLILKAHVGEFGA 208 D + ++ +++ + F++ID+ G E+++ I I++ A GL KAHVGEF Sbjct: 131 TIDQSFLKQWIEPMISSKVFKNIDLYGPEVSEGIEQCVYIFKLAEKYGLKKKAHVGEFSD 190 Query: 209 ADDVREAVEELGLQEVHHGIAAARSPQIMRWLSDHNIQLNVCPTSNIMLGVAENYGRHPI 268 A V+ VE L EV HGI AA++ +++++L+D I+ NVCP SNIMLG A++ HP+ Sbjct: 191 AASVKYFVEMFNLDEVQHGIGAAQNDKVLQFLADRKIRCNVCPQSNIMLGAAKDLKSHPL 250 Query: 269 RKLYDFGIPVTINTDDLLIFNQSVSREYMNLYKSGSITAEELNEI 313 RK+ D G+P++I TDD+L F ++ S ++ +L IT EE +++ Sbjct: 251 RKMMDAGVPISIGTDDILFFGKTNSEQFYDLVSEKVITEEEADQL 295 >B2S1Z3.1 ADD_TREPS Adenosine deaminase EC=3.5.4.4 Length = 299 Score = 149 bits (375), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 92/297 (30%), Positives = 144/297 (48%), Gaps = 4/297 (1%) Query: 22 SLTNLQTIPKSDLHNHAGRGGTIQYIGEWANIQIQPPSKPFQSLHGMQKWFDEHIKCHCP 81 SL ++ PK+D+H H + +W+ + I + + L M + E+ + C Sbjct: 3 SLEYYRSQPKADVHTHLNLSMKYERYKQWSGVVIPNFPRKMRGLDEMHEIIGEYTRPQCK 62 Query: 82 GIHGYLKRIEASFVQAAGDHIEKLALSFGIDEIDSLG-GMEHFTRIIDDLHRSFAPKTRF 140 L S A D++ + S I I ++HF + DLHR + Sbjct: 63 TAQDVLNLFTMSIEDAIADNVVVMETSVDIGFITHYEENLDHFLCDLSDLHRRYKRNVTL 122 Query: 141 LPELALDRACDIDEVYGRMDELLAFRWFRSIDICGDELAQPIACFKSIYRAANSAGLILK 200 EL + + + V + ++ F +ID+ G E+++ I F I++ A L K Sbjct: 123 HFELGISKIRERSFVEQWAEPMMRSGIFENIDLYGPEISEGIEDFIYIFKLAEKYHLKKK 182 Query: 201 AHVGEFGAADDVREAVEELGLQEVHHGIAAARSPQIMRWLSDHNIQLNVCPTSNIMLGVA 260 AHVGEF A VR VE L EV HGI AA ++R+L++ ++ NVCPTSN+ML Sbjct: 183 AHVGEFSDAQSVRHFVEIFNLDEVQHGIGAATDENVLRFLAERKVRCNVCPTSNVMLNAV 242 Query: 261 ENYGRHPIRKLYDFGIPVTINTDDLLIFNQSVSREYMNLYKSGSIT---AEELNEIR 314 E +HPI+K+ D G+ V + TDDLL F ++ S + ++ G IT AE L +R Sbjct: 243 ECLEKHPIKKMMDAGVRVGLGTDDLLFFGKTNSEQLFDMVSCGLITELHAEALLAVR 299 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.138 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,923,871,113 Number of extensions: 80195971 Number of successful extensions: 169636 Number of sequences better than 1.0e-05: 834 Number of HSP's gapped: 169516 Number of HSP's successfully gapped: 834 Length of query: 320 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 185 Effective length of database: 1,788,859,178 Effective search space: 330938947930 Effective search space used: 330938947930 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)