BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0124.0024.p (316 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A4J8Y7.1 A4J8Y7_DESRM Glucose-1-phosphate thymidylyltransferase ... 512 e-143 C3EBB0.1 C3EBB0_BACTU Glucose-1-phosphate thymidylyltransferase 501 e-140 B0MHD0.1 B0MHD0_9FIRM Glucose-1-phosphate thymidylyltransferase ... 440 e-121 A8SH27.1 A8SH27_9FIRM Glucose-1-phosphate thymidylyltransferase ... 439 e-121 B0NXP7.1 B0NXP7_9CLOT Glucose-1-phosphate thymidylyltransferase ... 439 e-121 >A4J8Y7.1 A4J8Y7_DESRM Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 292 Score = 512 bits (1318), Expect = e-143, Method: Compositional matrix adjust. Identities = 242/292 (82%), Positives = 273/292 (93%) Query: 25 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIKEILIISTAEDTPR 84 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGI++ILIIST EDTPR Sbjct: 1 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIQDILIISTPEDTPR 60 Query: 85 FKNLLGDGSQFGISLQYIVQPNPDGLAQAFILGESFIGEDSVAMILGDNIYYGNGMTKIL 144 FK+LLG+GSQFGI+L++ +QP+PDGLAQAF++GE FIGEDSVAMILGDNIYYGNGM KIL Sbjct: 61 FKSLLGNGSQFGINLEFKIQPSPDGLAQAFLIGEKFIGEDSVAMILGDNIYYGNGMRKIL 120 Query: 145 KEAARKKRGATVFGYHVPDPERFGVIEFDGEGKVLSVEEKPEHPKSNYAVTGLYFYDNRV 204 + AA K+ GATVFGYHV DP+RFGV+EFD GKV+SVEEKPE PKSNYA+TGLYFYDNRV Sbjct: 121 QRAANKESGATVFGYHVQDPQRFGVVEFDNNGKVISVEEKPEVPKSNYAITGLYFYDNRV 180 Query: 205 VSLAKEVKPSRRGELEITSINEAYLKLGELDVALLGRGFTWLDTGTHQSLVDATNFVRTI 264 V +AK VKPS RGELEITSINEA+LK+GEL+V LLGRGFTWLDTGTHQSLV+ATNFV+TI Sbjct: 181 VDIAKSVKPSLRGELEITSINEAFLKIGELEVELLGRGFTWLDTGTHQSLVEATNFVKTI 240 Query: 265 EDHQGIKISAPEEIAYINGWITKEHLLECGHKLSKTGYGQYLIKVATGKIQF 316 E+HQGIKI+APEEIAYINGWIT+E LL+CG KLSKT YGQYL++VA G+IQ+ Sbjct: 241 EEHQGIKIAAPEEIAYINGWITREQLLDCGEKLSKTVYGQYLMRVANGQIQY 292 >C3EBB0.1 C3EBB0_BACTU Glucose-1-phosphate thymidylyltransferase Length = 292 Score = 501 bits (1289), Expect = e-140, Method: Compositional matrix adjust. Identities = 240/292 (82%), Positives = 266/292 (91%) Query: 25 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIKEILIISTAEDTPR 84 MKGIILAGGSGTRLYPLTMVTSKQLLP+YDKPMIYYPLSTLMLAGI+EILIIST EDTPR Sbjct: 1 MKGIILAGGSGTRLYPLTMVTSKQLLPIYDKPMIYYPLSTLMLAGIREILIISTPEDTPR 60 Query: 85 FKNLLGDGSQFGISLQYIVQPNPDGLAQAFILGESFIGEDSVAMILGDNIYYGNGMTKIL 144 F++LLGDGSQFGISLQY VQP+PDGLAQAFI+GE FIG+DSVAM+LGDNIYYG+GM K+L Sbjct: 61 FESLLGDGSQFGISLQYKVQPSPDGLAQAFIIGEEFIGDDSVAMVLGDNIYYGSGMRKML 120 Query: 145 KEAARKKRGATVFGYHVPDPERFGVIEFDGEGKVLSVEEKPEHPKSNYAVTGLYFYDNRV 204 + AA+K+ GATVFGYHV DPERFGV+EFD GKVLSVEEKPE PKSNYA+TGLYFYDNRV Sbjct: 121 QRAAQKESGATVFGYHVHDPERFGVVEFDENGKVLSVEEKPEEPKSNYAITGLYFYDNRV 180 Query: 205 VSLAKEVKPSRRGELEITSINEAYLKLGELDVALLGRGFTWLDTGTHQSLVDATNFVRTI 264 V +AK VKPS RGELEITSINEAYL GEL+V LLGRGFTWLDTGTHQSLVDATNFV+T+ Sbjct: 181 VEIAKNVKPSARGELEITSINEAYLNKGELEVELLGRGFTWLDTGTHQSLVDATNFVKTV 240 Query: 265 EDHQGIKISAPEEIAYINGWITKEHLLECGHKLSKTGYGQYLIKVATGKIQF 316 EDHQGIKI+A EEI +INGWI KE L+E G + SK GYGQYL+KVA G I++ Sbjct: 241 EDHQGIKIAALEEIGFINGWINKETLIESGDQCSKNGYGQYLLKVANGGIKY 292 >B0MHD0.1 B0MHD0_9FIRM Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 293 Score = 440 bits (1131), Expect = e-121, Method: Compositional matrix adjust. Identities = 209/289 (72%), Positives = 245/289 (84%) Query: 25 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIKEILIISTAEDTPR 84 MKGIILAGGSGTRLYPLTMVTSKQLLP+YDKPMIYYPLS LM AGI+EILIIST +DTPR Sbjct: 1 MKGIILAGGSGTRLYPLTMVTSKQLLPIYDKPMIYYPLSVLMDAGIREILIISTPDDTPR 60 Query: 85 FKNLLGDGSQFGISLQYIVQPNPDGLAQAFILGESFIGEDSVAMILGDNIYYGNGMTKIL 144 F+ LLGDG QFGI L Y VQP+PDGLAQAFI+GE FIG+D+VAM+LGDNI++G+G+ K L Sbjct: 61 FEALLGDGHQFGIELSYEVQPSPDGLAQAFIIGEEFIGDDNVAMVLGDNIFHGHGLRKRL 120 Query: 145 KEAARKKRGATVFGYHVPDPERFGVIEFDGEGKVLSVEEKPEHPKSNYAVTGLYFYDNRV 204 + AA KK GATVFGY+V DPERFG++EFD +GK +S+EEKPEHPKSNY VTGLYFYDNRV Sbjct: 121 QAAANKKSGATVFGYYVDDPERFGIVEFDSDGKAISIEEKPEHPKSNYCVTGLYFYDNRV 180 Query: 205 VSLAKEVKPSRRGELEITSINEAYLKLGELDVALLGRGFTWLDTGTHQSLVDATNFVRTI 264 V AK + PS RGELEIT +N+ YL+ GEL+V LLG+GFTWLDTGTH+SLV+ATNFV+T+ Sbjct: 181 VEYAKNLAPSDRGELEITDLNKIYLENGELEVTLLGQGFTWLDTGTHESLVEATNFVKTV 240 Query: 265 EDHQGIKISAPEEIAYINGWITKEHLLECGHKLSKTGYGQYLIKVATGK 313 E HQ KI+ PEEIAY+ WIT++ LL+ L K YGQYL+ V GK Sbjct: 241 ETHQHRKIACPEEIAYLQHWITRDQLLKDIEPLKKNQYGQYLLDVMNGK 289 >A8SH27.1 A8SH27_9FIRM Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 295 Score = 439 bits (1130), Expect = e-121, Method: Compositional matrix adjust. Identities = 214/295 (72%), Positives = 247/295 (83%), Gaps = 3/295 (1%) Query: 25 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIKEILIISTAEDTPR 84 MKGIILAGG+GTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGI++ILIIST DTPR Sbjct: 1 MKGIILAGGAGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIQDILIISTPTDTPR 60 Query: 85 FKNLLGDGSQFGISLQYIVQPNPDGLAQAFILGESFIGEDSVAMILGDNIYYGNGMTKIL 144 F+ LLGDGSQ+GI LQY VQP+PDGLAQAFILGE FIG+D AMILGDNI+YGNG +K+L Sbjct: 61 FEALLGDGSQYGIHLQYKVQPSPDGLAQAFILGEEFIGDDCCAMILGDNIFYGNGFSKLL 120 Query: 145 KEA---ARKKRGATVFGYHVPDPERFGVIEFDGEGKVLSVEEKPEHPKSNYAVTGLYFYD 201 K A A K TVFGY+V DPERFG++EFD +GKVLSVEEKP+HPKSNYA+TGLYFY+ Sbjct: 121 KSAVANAENKGRCTVFGYYVQDPERFGIVEFDKDGKVLSVEEKPQHPKSNYAITGLYFYN 180 Query: 202 NRVVSLAKEVKPSRRGELEITSINEAYLKLGELDVALLGRGFTWLDTGTHQSLVDATNFV 261 VV +AK+VKPS RGELEITS+N+ YLK ELDV LLGRGF WLDTGT +SLV+A +FV Sbjct: 181 KEVVQMAKQVKPSARGELEITSLNDMYLKQDELDVQLLGRGFAWLDTGTMESLVEAADFV 240 Query: 262 RTIEDHQGIKISAPEEIAYINGWITKEHLLECGHKLSKTGYGQYLIKVATGKIQF 316 IE QGIKISAPEEIA+ GWI ++ LLE + K+ YGQ+L VA GK+++ Sbjct: 241 HMIEKRQGIKISAPEEIAFKYGWIDRDTLLESAERYGKSPYGQHLKNVADGKLRY 295 >B0NXP7.1 B0NXP7_9CLOT Glucose-1-phosphate thymidylyltransferase EC=2.7.7.24 Length = 293 Score = 439 bits (1129), Expect = e-121, Method: Compositional matrix adjust. Identities = 210/290 (72%), Positives = 244/290 (84%) Query: 25 MKGIILAGGSGTRLYPLTMVTSKQLLPVYDKPMIYYPLSTLMLAGIKEILIISTAEDTPR 84 MKGIILAGGSGTRLYPLTMVTSKQLLP+YDKPMIYYPLS LM AGI++ILIIST DTPR Sbjct: 1 MKGIILAGGSGTRLYPLTMVTSKQLLPIYDKPMIYYPLSVLMNAGIRDILIISTPSDTPR 60 Query: 85 FKNLLGDGSQFGISLQYIVQPNPDGLAQAFILGESFIGEDSVAMILGDNIYYGNGMTKIL 144 F++LLGDG QFG++L Y VQP+PDGLAQAFI+GE FIG+DSVAM+LGDNI++G+G+ K L Sbjct: 61 FESLLGDGHQFGVNLSYAVQPSPDGLAQAFIIGEDFIGDDSVAMVLGDNIFHGHGLKKRL 120 Query: 145 KEAARKKRGATVFGYHVPDPERFGVIEFDGEGKVLSVEEKPEHPKSNYAVTGLYFYDNRV 204 AA KK GATVFGY+V DPERFG++EFD +GK +S+EEKPE PKSNY VTGLYFYDN V Sbjct: 121 LRAANKKEGATVFGYYVDDPERFGIVEFDSDGKAISIEEKPEKPKSNYCVTGLYFYDNNV 180 Query: 205 VSLAKEVKPSRRGELEITSINEAYLKLGELDVALLGRGFTWLDTGTHQSLVDATNFVRTI 264 V AKE+KPS RGELEIT +N+ YL+ GELDV LLG+GFTWLDTGTH+SLV+ATNFV+T+ Sbjct: 181 VKYAKELKPSARGELEITDLNKIYLEKGELDVELLGQGFTWLDTGTHESLVEATNFVKTV 240 Query: 265 EDHQGIKISAPEEIAYINGWITKEHLLECGHKLSKTGYGQYLIKVATGKI 314 E HQ KI+ EEIAY+N WITK+ LL L K YGQYL+ V GK Sbjct: 241 ETHQHRKIACLEEIAYLNHWITKDQLLTDIEPLKKNQYGQYLMDVMAGKF 290 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.138 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,933,613,110 Number of extensions: 83441132 Number of successful extensions: 197342 Number of sequences better than 1.0e-05: 4254 Number of HSP's gapped: 194106 Number of HSP's successfully gapped: 4254 Length of query: 316 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 181 Effective length of database: 1,788,859,178 Effective search space: 323783511218 Effective search space used: 323783511218 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)