BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0124.0003.p (313 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K7C3.1 B3K7C3_9BACI ABC transporter related 456 e-126 A6TVR8.1 A6TVR8_ALKMQ ABC transporter related 316 2e-84 A0PYE1.1 A0PYE1_CLONN ABC-type multidrug transport system, ATP-a... 316 2e-84 Q4MPW6.1 Q4MPW6_BACCE Daunorubicin resistance ATP-binding protein 312 2e-83 B0KBI7.1 B0KBI7_THEP3 ABC transporter related 312 3e-83 >B3K7C3.1 B3K7C3_9BACI ABC transporter related Length = 315 Score = 456 bits (1172), Expect = e-126, Method: Compositional matrix adjust. Identities = 219/313 (69%), Positives = 254/313 (81%) Query: 1 MKMAFAVLSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGG 60 M F + DVVKRY KL+VDH+N + EGEIFGLLGPNGAGKST+I+MICGLL D G Sbjct: 3 MMTVFLEMKDVVKRYGSKLSVDHMNLEVHEGEIFGLLGPNGAGKSTSINMICGLLAKDQG 62 Query: 61 DIVIDGLSVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEA 120 I IDG+S+ +PLEVK+RIGLVPQ+LALYE M+A +NV+FF ERVEEA Sbjct: 63 IIKIDGISIEEQPLEVKRRIGLVPQDLALYEEMSAWDNVAFFAKLYGLRGHLLKERVEEA 122 Query: 121 LAFTGLSDRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVK 180 LAF GL DRAK++PSTFSGGMKRRLNIAC+I HRPKLIIMDEPTVGIDPQSRNHILESVK Sbjct: 123 LAFVGLQDRAKERPSTFSGGMKRRLNIACSITHRPKLIIMDEPTVGIDPQSRNHILESVK 182 Query: 181 ALNKLGSTVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHI 240 LN++GSTVIYTSHYMEEVAAI DRVAIMD+GH+IACGT++ELR RVAHEE+I++ A I Sbjct: 183 TLNRMGSTVIYTSHYMEEVAAISDRVAIMDQGHVIACGTQQELRARVAHEEKIILTADGI 242 Query: 241 TPALIQELGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLE 300 TP L++EL HPR+ R N + VE+Y+PS+Q ELQDILFI +KH + SL EEP LE Sbjct: 243 TPDLVEELTIHPRVRRVAQNDNEVEVYVPSAQDELQDILFICSKHHTTLRSLQCEEPGLE 302 Query: 301 TLFLSLTGRTLRD 313 TLFLSLTGRTLRD Sbjct: 303 TLFLSLTGRTLRD 315 >A6TVR8.1 A6TVR8_ALKMQ ABC transporter related Length = 310 Score = 316 bits (810), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 160/304 (52%), Positives = 208/304 (68%) Query: 10 DVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDGLSV 69 ++VKRY + + VDHVN SI+EG IFGLLGPNGAGKST I+M+ GL + DGG+I I G + Sbjct: 7 NIVKRYGESIAVDHVNLSIKEGAIFGLLGPNGAGKSTMINMMIGLARIDGGEIKILGKDI 66 Query: 70 LSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGLSDR 129 + VK IG+VPQ++A++E++TA ENV+FF + VEEALAF GL DR Sbjct: 67 KKHEMFVKSHIGIVPQDIAIFEDLTAEENVTFFGKLYGLKGSSLKQGVEEALAFVGLWDR 126 Query: 130 AKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNKLGSTV 189 K +SGGMKRRLNIACAI H+PKLIIMDEPTVGIDPQSRN IL+SVKALN++GSTV Sbjct: 127 RKQFSKNYSGGMKRRLNIACAIAHKPKLIIMDEPTVGIDPQSRNLILQSVKALNQMGSTV 186 Query: 190 IYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQELG 249 IYTSHYMEEV IC V IMD G IIA GT+ EL+E ++ EE+I V+ + I+ + + + Sbjct: 187 IYTSHYMEEVEEICTDVTIMDHGKIIAQGTKEELKELISSEEKITVEISTISHTVGENIK 246 Query: 250 KHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETLFLSLTGR 309 K + L +E+ + +I+ + + S N+E P LE +FL+LTGR Sbjct: 247 KIDGVRECTLRDQYLEVISQKNSKNTGEIIDAVLESGSKVQSFNVESPTLEDVFLTLTGR 306 Query: 310 TLRD 313 +LRD Sbjct: 307 SLRD 310 >A0PYE1.1 A0PYE1_CLONN ABC-type multidrug transport system, ATP-ase compoment CAC0241 Length = 313 Score = 316 bits (809), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 149/313 (47%), Positives = 218/313 (69%) Query: 1 MKMAFAVLSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGG 60 MK+ ++VKRY + L +D+ + S++EGEIFGLLGPNGAGK+T I++I GLLK+ G Sbjct: 1 MKILILEAKNIVKRYGEHLAIDNASLSVREGEIFGLLGPNGAGKTTLINIIVGLLKSYSG 60 Query: 61 DIVIDGLSVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEA 120 ++ + G ++ + +K +IG+ PQE AL+ ++TA ENV+FF + V+EA Sbjct: 61 EVNVFGKDLVKDEMYIKSQIGIAPQEAALFHDLTAYENVTFFGRLYGLKGKELKDGVKEA 120 Query: 121 LAFTGLSDRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVK 180 L FT L DR KD P +SGGMKRRLNIACAI+H+PKLIIMDEPTVGIDPQSR HIL S+K Sbjct: 121 LEFTELWDRRKDYPKQYSGGMKRRLNIACAIVHKPKLIIMDEPTVGIDPQSRKHILNSIK 180 Query: 181 ALNKLGSTVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHI 240 LNK+GST+IYTSHYMEE+ +CD + IMDKG +IA GT+ EL+E +A E+++ + ++I Sbjct: 181 KLNKMGSTIIYTSHYMEEIEDLCDEIVIMDKGKVIAKGTKEELKELIATEDKVSIGVSNI 240 Query: 241 TPALIQELGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLE 300 + ++I ++ K + ++ + + + + + L +I+ I + I +N+++P LE Sbjct: 241 SYSIIDKIKKVQGVKECVIDNNVINIISKNGSANLSEIIDIIVDYGAEINKINMDKPSLE 300 Query: 301 TLFLSLTGRTLRD 313 +FL+LTGR LRD Sbjct: 301 GVFLTLTGRKLRD 313 >Q4MPW6.1 Q4MPW6_BACCE Daunorubicin resistance ATP-binding protein Length = 310 Score = 312 bits (800), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 156/309 (50%), Positives = 213/309 (68%), Gaps = 3/309 (0%) Query: 7 VLSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDIVIDG 66 V+ + K + +K + +V+F +++GE FGLLGPNGAGKSTTISMICGL+ D GDI + G Sbjct: 3 VIDHITKSFGKKEIIKNVSFEVKKGETFGLLGPNGAGKSTTISMICGLISYDSGDIKVGG 62 Query: 67 LSVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALAFTGL 126 SV PLE KK+IG+VPQ++ALY ++A EN+ F+ ER EE LA+ GL Sbjct: 63 KSVKEYPLEAKKKIGIVPQDIALYPTLSAKENLVFWGKMYGLNGKIAKERAEEVLAYVGL 122 Query: 127 SDRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKALNKLG 186 DR KDK TFSGGMKRR+NI A+MH P+L+IMDEPTVGIDPQSRNHILE+VK LN+ G Sbjct: 123 QDRGKDKIETFSGGMKRRINIGAALMHEPELLIMDEPTVGIDPQSRNHILETVKKLNEKG 182 Query: 187 STVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITPALIQ 246 +TVIYTSHYMEEV +C+R+AI+D G +IA GT+REL R+A + ++ + L+Q Sbjct: 183 TTVIYTSHYMEEVEYLCERIAIVDHGKVIALGTKRELCNRLADGFIVRLQLNRYSTELLQ 242 Query: 247 ELGKHPRINRAELNGD--TVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETLFL 304 +L + R + D T+++ L +S + ++ + ++ I L ++EP+LE LFL Sbjct: 243 KLKALSVVERIIFDEDNSTIDIGLNGGES-IGTVVSVVVENNAQILKLEVQEPNLEALFL 301 Query: 305 SLTGRTLRD 313 LTGR+LRD Sbjct: 302 QLTGRSLRD 310 >B0KBI7.1 B0KBI7_THEP3 ABC transporter related Length = 311 Score = 312 bits (799), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 159/311 (51%), Positives = 205/311 (65%) Query: 3 MAFAVLSDVVKRYDQKLTVDHVNFSIQEGEIFGLLGPNGAGKSTTISMICGLLKADGGDI 62 M + +V+KR+ + +D+VN I+EGEI+GLLGPNGAGK+T IS+ICGL+ D G++ Sbjct: 1 MKIVKMKEVIKRFGDVIALDNVNLEIEEGEIYGLLGPNGAGKTTAISIICGLISFDRGEV 60 Query: 63 VIDGLSVLSKPLEVKKRIGLVPQELALYENMTATENVSFFXXXXXXXXXXXXERVEEALA 122 + + +KK IG+VPQ++A+Y ++TA ENV FF E VE AL Sbjct: 61 YVFDKDIRKDAEFIKKNIGIVPQDVAIYGDLTAYENVKFFASLYGLRGKELKESVEMALE 120 Query: 123 FTGLSDRAKDKPSTFSGGMKRRLNIACAIMHRPKLIIMDEPTVGIDPQSRNHILESVKAL 182 F GLSD+AK+ P+ FSGGMKRRLNIACAI HRPKLIIMDEPTVGIDPQSRNHILESVK L Sbjct: 121 FVGLSDKAKEVPNKFSGGMKRRLNIACAIAHRPKLIIMDEPTVGIDPQSRNHILESVKKL 180 Query: 183 NKLGSTVIYTSHYMEEVAAICDRVAIMDKGHIIACGTERELRERVAHEERIVVKAAHITP 242 N++GST+IYTSHYMEEV AIC R++IMD G +IA GT+ EL V + ++ I Sbjct: 181 NEMGSTIIYTSHYMEEVEAICTRISIMDHGKVIAEGTKEELTSMVTDVNTVYIEIGSIDG 240 Query: 243 ALIQELGKHPRINRAELNGDTVELYLPSSQSELQDILFIFAKHEGVIASLNIEEPDLETL 302 +EL + E+ T+++ S DI+ F I +L E PDLET+ Sbjct: 241 IKEEELKGIKGVKAVEIRDSTIKITSLKDVSNFDDIIHYFISKNIPIRNLRNEIPDLETV 300 Query: 303 FLSLTGRTLRD 313 FL+LTGR LRD Sbjct: 301 FLTLTGRKLRD 311 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,675,458,035 Number of extensions: 64831919 Number of successful extensions: 514919 Number of sequences better than 1.0e-05: 95450 Number of HSP's gapped: 380003 Number of HSP's successfully gapped: 103411 Length of query: 313 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 178 Effective length of database: 1,788,859,178 Effective search space: 318416933684 Effective search space used: 318416933684 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)