BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0124.0002.p (387 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K7C4.1 B3K7C4_9BACI Histidine kinase dimerisation and phosphoa... 254 1e-65 C5AL43.1 C5AL43_BURGL Sensor histidine kinase 84 2e-14 A3MGZ8.1 A3MGZ8_BURM7 Sensor histidine kinase 80 2e-13 A2RZR1.1 A2RZR1_BURM9 Sensor histidine kinase 80 2e-13 A1UXJ5.1 A1UXJ5_BURMS Sensor histidine kinase 80 2e-13 >B3K7C4.1 B3K7C4_9BACI Histidine kinase dimerisation and phosphoacceptor region Length = 419 Score = 254 bits (648), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 141/375 (37%), Positives = 201/375 (53%), Gaps = 1/375 (0%) Query: 8 LRYALMIIPXXXXXXXXXXXXXXXFTFHFXXXXXXXXXXXXXSGP-FRALACAIELLYTA 66 LRY L+++P + +F P +R A +E+ + Sbjct: 41 LRYGLILLPAAADIFLQQLDDYGEYMVYFLLFLAIAVLSRFLPSPAYRKAAILLEIPLSL 100 Query: 67 WLCWHYGDLMIFPAVSAMLNYSRLENRLMVLVFFVIHAVALNVALSGSEPQVRVVMNLTF 126 WLC YG +M+F ++S++ Y L R L H LN+A++ + + NL F Sbjct: 101 WLCHQYGFMMVFLSLSSLCVYLPLFERPGKLWLAFGHLALLNIAITDYDALLHTTANLLF 160 Query: 127 LLSAALNKLLMRSGRGRVDTLFLYDELRKKHFELEEARSSLLQFTXXXXXXXXXXXXXXX 186 L A + + +D + LYDEL++ HF+ +EA LLQF Sbjct: 161 LFLAVTFHRIHEMNQKELDHIHLYDELKRLHFQQDEAGRQLLQFAHQVESAAQAEERNRI 220 Query: 187 XXXLHDDIGHRLIRVKMMTEAAIHTLPHSQETGMEMMNQIRDQLAASMDDMRAAVRRINY 246 LHDDIGHRLIRVKMM EAA+H +P GM+M++QIRDQL SM+ MR AV+++N Sbjct: 221 SRQLHDDIGHRLIRVKMMMEAALHIVPQDTARGMDMLHQIRDQLGESMEQMRTAVKQMNP 280 Query: 247 GSQLEGAYALDRLLEELGRDTGIETSYQVHGMPYPLYPSVRVTLYKNAQEALTNAIRHGR 306 ++ Y+LDRLLEE GR+TGIET + G+PYPLYPS +V LYKNA+EA+TNAIRHG Sbjct: 281 SRRITDDYSLDRLLEETGRETGIETELVLQGIPYPLYPSQQVVLYKNAREAITNAIRHGE 340 Query: 307 ATAIWINVSFSEQEVAMEVGNNGQRPEENPXXXXXXXXXXXXXXXAERVHLIGGTLELQL 366 A + I + + ++EV MEV N+G EE ER ++GG LE++ Sbjct: 341 AKQVQIFLQYGDEEVRMEVSNDGMVQEEAKPIAAADRHGIGISGMLERTKVVGGALEVRK 400 Query: 367 EPEFAVITRVALHSQ 381 F VITR+ ++ + Sbjct: 401 SVPFTVITRLPVYRK 415 >C5AL43.1 C5AL43_BURGL Sensor histidine kinase Length = 465 Score = 84.3 bits (207), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 63/198 (31%), Positives = 97/198 (48%), Gaps = 20/198 (10%) Query: 190 LHDDIGHRLIRVKMMTEAAIHTLPHSQETGMEMMNQIRDQLAASMDDMRAAVRRINYG-- 247 LHD I ++ VK+M E+A+ S + +A D +R VRRI++ Sbjct: 261 LHDGISQMMVSVKLMLESALERFERSPARDAAAEGVLAKSVARLGDVLRE-VRRISHALR 319 Query: 248 ----SQLEGAYALDRLLEELGRDTGIETSYQ--VHGMPYPLYPSVRVTLYKNAQEALTNA 301 L A ALD+L+ ELG +TG+E Y VH PL +V L++ AQEALTN Sbjct: 320 PAMLDDLGLAAALDQLVRELGSETGVELGYTQIVHSGSRPLPAAVNTALFRIAQEALTNL 379 Query: 302 IRHGRATAIWINVSFSEQEVAMEVGNNG-----QRPEENPXXXXXXXXXXXXXXXAERVH 356 +RH +AT +++ + VA+ V +NG +R + +P ER+ Sbjct: 380 VRHAQATRGAVSLEIAAHSVALAVADNGCGFDVERIQADPHGGVGLRNMR------ERID 433 Query: 357 LIGGTLELQLEPEFAVIT 374 IGGTL ++ +P V++ Sbjct: 434 AIGGTLAIRSQPGHTVVS 451 >A3MGZ8.1 A3MGZ8_BURM7 Sensor histidine kinase Length = 466 Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 61/183 (33%), Positives = 90/183 (49%), Gaps = 10/183 (5%) Query: 190 LHDDIGHRLIRVKMMTEAAIHTLPHSQETGMEMMNQIRDQLAASMDDMRAAVRRINYG-- 247 LHD I ++ K+M E+A+ L H + +A D +R VRRI++ Sbjct: 261 LHDGISQMMVSAKLMCESALERLAHLPARENAAQAALSKGIARLGDTLRE-VRRISHALR 319 Query: 248 ----SQLEGAYALDRLLEELGRDTGIETSY-QV-HGMPYPLYPSVRVTLYKNAQEALTNA 301 L A ALD+L+ ELG +TG+E + QV H PL V+ L++ AQEALTN Sbjct: 320 PTMLDDLGLAAALDQLVRELGAETGVELGFTQVDHSGAPPLPAPVKTALFRIAQEALTNI 379 Query: 302 IRHGRATAIWINVSFSEQEVAMEVGNNGQRPEENPXXXXXXXXXXXXXXXAERVHLIGGT 361 +RH AT + + S +EVA+ + +NG R + ER+ +GGT Sbjct: 380 LRHAHATRAAVTLELSPREVALTIADNG-RGFDAGRAQADARGGIGLRKMRERLDALGGT 438 Query: 362 LEL 364 LE+ Sbjct: 439 LEI 441 >A2RZR1.1 A2RZR1_BURM9 Sensor histidine kinase Length = 466 Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 61/183 (33%), Positives = 90/183 (49%), Gaps = 10/183 (5%) Query: 190 LHDDIGHRLIRVKMMTEAAIHTLPHSQETGMEMMNQIRDQLAASMDDMRAAVRRINYG-- 247 LHD I ++ K+M E+A+ L H + +A D +R VRRI++ Sbjct: 261 LHDGISQMMVSAKLMCESALERLAHLPARENAAQAALSKGIARLGDTLRE-VRRISHALR 319 Query: 248 ----SQLEGAYALDRLLEELGRDTGIETSY-QV-HGMPYPLYPSVRVTLYKNAQEALTNA 301 L A ALD+L+ ELG +TG+E + QV H PL V+ L++ AQEALTN Sbjct: 320 PTMLDDLGLAAALDQLVRELGAETGVELGFTQVDHSGAPPLPAPVKTALFRIAQEALTNI 379 Query: 302 IRHGRATAIWINVSFSEQEVAMEVGNNGQRPEENPXXXXXXXXXXXXXXXAERVHLIGGT 361 +RH AT + + S +EVA+ + +NG R + ER+ +GGT Sbjct: 380 LRHAHATRAAVTLELSPREVALTIADNG-RGFDAGRAQADARGGIGLRKMRERLDALGGT 438 Query: 362 LEL 364 LE+ Sbjct: 439 LEI 441 >A1UXJ5.1 A1UXJ5_BURMS Sensor histidine kinase Length = 466 Score = 80.5 bits (197), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 61/183 (33%), Positives = 90/183 (49%), Gaps = 10/183 (5%) Query: 190 LHDDIGHRLIRVKMMTEAAIHTLPHSQETGMEMMNQIRDQLAASMDDMRAAVRRINYG-- 247 LHD I ++ K+M E+A+ L H + +A D +R VRRI++ Sbjct: 261 LHDGISQMMVSAKLMCESALERLAHLPARENAAQAALSKGIARLGDTLRE-VRRISHALR 319 Query: 248 ----SQLEGAYALDRLLEELGRDTGIETSY-QV-HGMPYPLYPSVRVTLYKNAQEALTNA 301 L A ALD+L+ ELG +TG+E + QV H PL V+ L++ AQEALTN Sbjct: 320 PTMLDDLGLAAALDQLVRELGAETGVELGFTQVDHSGAPPLPAPVKTALFRIAQEALTNI 379 Query: 302 IRHGRATAIWINVSFSEQEVAMEVGNNGQRPEENPXXXXXXXXXXXXXXXAERVHLIGGT 361 +RH AT + + S +EVA+ + +NG R + ER+ +GGT Sbjct: 380 LRHAHATRAAVTLELSPREVALTIADNG-RGFDAGRAQADARGGIGLRKMRERLDALGGT 438 Query: 362 LEL 364 LE+ Sbjct: 439 LEI 441 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.324 0.137 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,721,224,437 Number of extensions: 56545686 Number of successful extensions: 177930 Number of sequences better than 1.0e-05: 411 Number of HSP's gapped: 178584 Number of HSP's successfully gapped: 411 Length of query: 387 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 249 Effective length of database: 1,760,596,133 Effective search space: 438388437117 Effective search space used: 438388437117 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 132 (55.5 bits)