BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0117.0011.p (638 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K495.1 B3K495_9BACI Histidine kinase internal region 658 0.0 B1D501.1 B1D501_9BACL Signal transduction histidine kinase, LytS 359 4e-97 A9U718.1 A9U718_PHYPA Predicted protein 273 6e-71 A4XMI9.1 A4XMI9_CALS8 Integral membrane sensor signal transducti... 252 7e-65 A9KLC0.1 A9KLC0_CLOPH Histidine kinase internal region 236 4e-60 >B3K495.1 B3K495_9BACI Histidine kinase internal region Length = 667 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/631 (52%), Positives = 444/631 (70%), Gaps = 10/631 (1%) Query: 10 KQTGALWSSFNYWWGRRSLQSRLVAAYIFIILGPCLLVSLYSYKSINNTYVRDAVDKNSY 69 K+ +L SF YW GRRS+QSRLVAAYI I+L P ++VS Y +K I +TY+ DA+++NS+ Sbjct: 29 KRMASLIQSFTYWIGRRSMQSRLVAAYILILLIPSMIVSNYFFKQIRDTYISDALNQNSF 88 Query: 70 LLQMEKLHILNQIEAMERAAQMAYSDKAVQNYLLNEHDPSLGELIDFNTTTFMNLSRIQI 129 LL++EK+++LNQIEA+E AAQ+A SD +++YL +P LID F ++ RIQ Sbjct: 89 LLEIEKMNMLNQIEAIEMAAQLAISDDGIKDYLRINEEPEPAWLIDLAWGPFKDIQRIQT 148 Query: 130 NNPNIEHLRLYSGSGEVHELWPIIFREERVSMEPWFQKALKLEGQELWSFQNEDPDLMQR 189 NNPNI HLRLY+ + V E+WPIIF E+R++ EPWF K +L+G E+W F + DPD++QR Sbjct: 149 NNPNITHLRLYTNNSYVTEMWPIIFHEKRIASEPWFPKVKELDGGEMWVFNHRDPDILQR 208 Query: 190 YSGDPPKGQPKVSLLREISIPAGHHVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIAGEDL 249 Y+ D + QPKVSL+R++ G++ G+IQVDMLL F PKT+ + DN SQM I ++ Sbjct: 209 YAADVSEEQPKVSLIRQVH--NGNYSGVIQVDMLLKYFAPKTFAGIVDNSSQMVIVDQEG 266 Query: 250 QLFTRADHSFVQDNPQLTGAIA---GRLQQYAETGEWDIH--YKEKGNSFLLIHTPLTEI 304 +LF SF+ + L + +L+ E +H + G+SFLLI TP+ + Sbjct: 267 KLFMDRSQSFMTSHEGLRDEVELQFAKLKLQTGDSEETMHARFSLDGSSFLLIATPMERL 326 Query: 305 GASLVNVVSMEGVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKA 364 A ++NVVS+EG + ++S + II N+ I+L++ I Y LN+ ILK+LRRLTETMK+ Sbjct: 327 HAHVLNVVSLEGALNNVSKAQGQIIAANVVLIILLSIITYYLNSIILKSLRRLTETMKRV 386 Query: 365 RRGEAYTGFSIRGGGEVGELAHHFSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAH 424 R+GE +IRGGGEVGELAHHF+KL+ TIN L+AQ V K+A++KEAELRTLH+QID+H Sbjct: 387 RKGEVTAAIAIRGGGEVGELAHHFNKLIRTINELIAQGVRKQAVTKEAELRTLHSQIDSH 446 Query: 425 FLYNTLENIKMLAEIENQRGISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMN 484 FLYNTLENIKMLAEIE QR ISDALTSLGGMMRYNFKWSGEYVKLRDEIRHI NYI+VMN Sbjct: 447 FLYNTLENIKMLAEIEGQRTISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIRNYIDVMN 506 Query: 485 IRFEYPILLELEVDAPYLELEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADG 544 IRF+ PI LEL + + ++ELEVLKMSLQP+VEN+VKHAW E Q + I+I + + Sbjct: 507 IRFDEPIRLELNIPSEFMELEVLKMSLQPIVENAVKHAWP--EFPDQEKQIKIDVIAWEE 564 Query: 545 D-IFIAIRDNGFGLTPERLTELHSSIYAKEEPGADASXXXXXXXXXXXXXLRNVHQRLQL 603 D I I + DNG G+ P RL L + ++ + LRNVHQR++L Sbjct: 565 DQITINVTDNGIGIEPYRLGRLGEILRTADDEELPSGDYGRGGVQAGGIGLRNVHQRIRL 624 Query: 604 FYGEAYGLEVQSQAGEWTTVFMTLPKVLLTG 634 FYG YG+E++S+ G++T V MT PKVLLTG Sbjct: 625 FYGNEYGIELKSEKGKFTQVTMTFPKVLLTG 655 >B1D501.1 B1D501_9BACL Signal transduction histidine kinase, LytS Length = 633 Score = 359 bits (922), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 215/618 (34%), Positives = 338/618 (54%), Gaps = 16/618 (2%) Query: 25 RRSLQSRLVAAYIFIILGPCLLVSLYSYKSINNTYVRDAVDKNSYLLQMEKLHILNQIEA 84 + SLQ +L+ +++F+I P +L S Y+ + + + N +L +EK++I N +E Sbjct: 18 KLSLQVKLILSFVFVIFIPVILFSWYTLNEESAKAMEELTKNNENVLAIEKINIENNMEL 77 Query: 85 MERAAQMAYSDKAVQNYLLNEHDPSLGELIDFNTTTFMNLSRIQINNPNIEHLRLYSGSG 144 ME Q+A S++ + NYL E ++ N NNP I ++RL++ + Sbjct: 78 MEWTGQLALSNREMNNYLQIEQIQDAAHVLHIKKDVVNNFQYFLFNNPRIANVRLFTDNL 137 Query: 145 EVHELWPIIFREERVSMEPWFQKALKLEGQELWSFQNEDPDLMQRYSGDPPKGQPKVSLL 204 V+E+WP+I +E R+ +PW + +K G LW Q ED ++ +P +P ++ L Sbjct: 138 YVNEIWPVILQESRIEDKPWHDEVVKRSGLPLWEIQ-EDV-VLTGVPSEPQPNEPFMTYL 195 Query: 205 REISIPAGH-HVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIAGEDLQLFT-RADHSFVQD 262 +E H G++++ M LS F +T++ V+DN SQ+ + + Q+++ A F Q Sbjct: 196 QEFKYADNRAHNGILEISMQLSDFFSQTFSSVQDNNSQLIVIARNGQVYSLEASPVFAQH 255 Query: 263 NPQLTGAIAGRLQQYAETGEWDIHYKEKGNSFLLIHTPLTEIGASLVNVVSMEGVMKDIS 322 + + + R++ + T + +K G S+L T + I LVN+VS+ M+ I+ Sbjct: 256 SAE---QLMNRVKLTSNTDYETVKFKVSGQSYLAFQTYIPSIDLHLVNMVSLADTMEGIN 312 Query: 323 HTRN---LIIGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKARRGEAYTGFS-IRGG 378 H+R ++I L + F+V+ ++Y + AFIL+ L+ L E+M++ R G I G Sbjct: 313 HSRVRYLVLISLLVAFLVV---LSYSMQAFILRRLKVLRESMQQVRSGNFNVELPPITGS 369 Query: 379 GEVGELAHHFSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAHFLYNTLENIKMLAE 438 EVGEL H+ +L+ IN L+ + + A KEAEL+ L NQID+HFLYNTLEN+KMLAE Sbjct: 370 DEVGELGFHYRELILKINELIQEQAARHAAGKEAELKALKNQIDSHFLYNTLENVKMLAE 429 Query: 439 IENQRGISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPILLELEVD 498 IE Q ISD +TSLGGMMRY+ +W ++V L DEI+ +++YI VMNIR++ + L L + Sbjct: 430 IEGQYLISDIMTSLGGMMRYSMEWKQDHVMLSDEIKQVQHYISVMNIRYDGRLDLRLSIA 489 Query: 499 APYLELEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADGDIFIAIRDNGFGLT 558 L+ E LKMSLQPVVEN++KH + N + I I I D+G G+ Sbjct: 490 QECLKQETLKMSLQPVVENAIKHGMSRMHSSDGNLVVAISADRRGHACVIEITDSGCGIP 549 Query: 559 PERLTELHSSIYAKEEPGADASXXXXXXXXXXX--XXLRNVHQRLQLFYGEAYGLEVQSQ 616 L L+ + +E D LRNV QRL + YG YG+ ++SQ Sbjct: 550 EGMLNLLNQMLRMEESAYQDVRQLVVRKDNQDSNGIGLRNVDQRLVMSYGPEYGIRIESQ 609 Query: 617 AGEWTTVFMTLPKVLLTG 634 G +T + MTLP L G Sbjct: 610 EGSYTRIIMTLPYRLTGG 627 >A9U718.1 A9U718_PHYPA Predicted protein Length = 450 Score = 273 bits (697), Expect = 6e-71, Method: Compositional matrix adjust. Identities = 162/429 (37%), Positives = 246/429 (57%), Gaps = 15/429 (3%) Query: 214 HVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIAGEDLQLFTRADHSFVQDNPQLTGA--IA 271 H G++++ M LS F +T++ V+D SQ+ + + Q+F+ D S + N GA + Sbjct: 28 HNGILEISMQLSDFFSQTFSSVQDKNSQLIVVARNGQVFSLKDSSVFKQN----GAEELI 83 Query: 272 GRLQQYAETGEWDIHYKEKGNSFLLIHTPLTEIGASLVNVVSMEGVMKDISHTRN---LI 328 ++ + T + +K G+S+L + + + I LVN+ S+E M+ I+H+R ++ Sbjct: 84 SSIKLTSHTDYETVRFKVNGHSYLALQSYIPSIDVHLVNMASLEETMEGINHSRVRYIVL 143 Query: 329 IGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKARRGEAYTGFS-IRGGGEVGELAHH 387 + L F+VL ++Y + A IL+ L+ L E+M++ R G I G EVGEL H Sbjct: 144 VSLLAAFLVL---LSYSMQAIILRRLKALRESMQQVRNGNFNVELPPITGTDEVGELGFH 200 Query: 388 FSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAHFLYNTLENIKMLAEIENQRGISD 447 + KL+ IN L+ ++A KEAELR L NQID+HFLYNTLEN+KMLAEIE Q ISD Sbjct: 201 YRKLILKINELIQDQAARQAAGKEAELRALKNQIDSHFLYNTLENVKMLAEIEGQYLISD 260 Query: 448 ALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPILLELEVDAPYLELEVL 507 +TSLGGMMRY+ +W ++V L DEI+ +++Y+ VMNIR++ + L+L ++ L+ E L Sbjct: 261 IMTSLGGMMRYSMEWRQDHVMLSDEIQQVQHYVSVMNIRYDGRLDLQLSIEPECLKQESL 320 Query: 508 KMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADGDIFIAIRDNGFGLTPERLTELHS 567 KMSLQPVVEN++KH + + N I I I I D+G G+ E L L+ Sbjct: 321 KMSLQPVVENAIKHGMSRMHSKDGNLLITISAVRRGQACVIEITDSGRGIPDETLGLLNQ 380 Query: 568 SIYAKEEPGADASX--XXXXXXXXXXXXLRNVHQRLQLFYGEAYGLEVQSQAGEWTTVFM 625 + +E + LRNV QRL + YG YG+ ++SQ G +T + M Sbjct: 381 MLRMEEHAYQEVRQLFVRKENEDGNGIGLRNVDQRLVMSYGVEYGIRIESQEGSYTRIIM 440 Query: 626 TLPKVLLTG 634 TLP ++ G Sbjct: 441 TLPYRVMGG 449 >A4XMI9.1 A4XMI9_CALS8 Integral membrane sensor signal transduction histidine kinase Length = 614 Score = 252 bits (644), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 172/617 (27%), Positives = 318/617 (51%), Gaps = 39/617 (6%) Query: 25 RRSLQSRLVAAYIFIILGPCLLVSLYSYKSINNTYVRDAVDKNSYLLQMEKLHILNQIEA 84 + +++ +L+ +YI I+ P ++ + +++++ + ++ ++ ++ ++ K I+ +E Sbjct: 17 KLNVRQKLIFSYILIVAIPISILQINAFQNVKDMTEKEYINNIAFEVEKLKSDIVKNVEQ 76 Query: 85 MERAAQMAYSDKAVQNYLLNEHDPSLGELIDFNTTTFMNLSRIQINNPNIEHLRLYSGSG 144 +A Q +++ +++ + S E+ F + +Q N NI +R ++ + Sbjct: 77 YVKATQFILNNQDFIDFVSIYQERSPEEIFSFKVNVLDEIEYLQYVNFNINRIRFFTNNV 136 Query: 145 EVHELWPIIFREERVSMEPWFQKAL-KLEGQELWSFQNEDPDLMQRYSGDPPKGQPKV-S 202 + E WP++++ +R+ + + L E LW N D G P KV S Sbjct: 137 FLPETWPVLYQLDRIKNQKYIADFLDNPEKISLWKINNTDN------LGPPLNNDTKVVS 190 Query: 203 LLREISIPAGHHVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIA----GE-----DLQLFT 253 ++ G+ VG+I+V+ML F T R N++ + +A GE L F Sbjct: 191 YYTKVIDSVGNLVGIIEVNMLTDEFFANELT--RSNRNSVMVAITKDGEIVYNHQLSDFL 248 Query: 254 RADHSFVQDNPQLTGAIAGRLQQYAETGEWDIHYKEKG-NSFLLIHTPLTEIGASLVNVV 312 R ++D + +++ T +I Y G S ++T + +G L VV Sbjct: 249 RTLKIDLKDFKEFL------IKKTDVTKNEEIVYFRLGRTSAAFVYTYVPMLGMYLYKVV 302 Query: 313 SMEGVMKDISHTRNLIIGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKARRGEAYTG 372 + + + I+ ++ + + + +A+ +V+ + IL+ L+ + TM+K G+ Sbjct: 303 LFDALTQKINQLTIKMLWQVVVLMFISSALIFVIISLILRKLKDIISTMRKVENGDFDVK 362 Query: 373 FSIRGGGEVGELAHHFSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAHFLYNTLEN 432 I+G E+ ELA HF K++ I L+ V KE K+A+++ L +QI+AHF+YN LEN Sbjct: 363 IEIKGDDEIDELAFHFQKMIERIKVLIVDTVKKELAQKDAQIKALQSQINAHFIYNVLEN 422 Query: 433 IKMLAEIENQRGISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPIL 492 IKM+AE + +SDA+T LG MMRYN W ++V L DE+ +I+NY+ +MN+RF+ I Sbjct: 423 IKMMAECKEDYEVSDAITKLGKMMRYNMSWKRKFVTLYDELENIKNYVALMNLRFDKEIK 482 Query: 493 LELEV-DAPYLELEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADGDIFIAIR 551 L + + + L EV K+ LQP++ENS+ + E + + SI I + + I I Sbjct: 483 LMINIYNEEILNYEVPKLILQPIIENSITYGI---EPKGEGGSIFIDANVIGEFLVITIV 539 Query: 552 DNGFGLTPERLTELHSSIYAKEEPGADASXXXXXXXXXXXXXLRNVHQRLQLFYGEAYGL 611 D+G G+ E+L ++ +I E G DA L+NV++R++L YG+AYGL Sbjct: 540 DDGKGIEEEKLRQIQEAI----EKGIDAE-----CYHGQGIALKNVNERIKLTYGKAYGL 590 Query: 612 EVQSQAGEWTTVFMTLP 628 +++S+ E+T V +TLP Sbjct: 591 KIESKENEFTKVTITLP 607 >A9KLC0.1 A9KLC0_CLOPH Histidine kinase internal region Length = 599 Score = 236 bits (603), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 159/608 (26%), Positives = 306/608 (50%), Gaps = 26/608 (4%) Query: 28 LQSRLVAAYIFIILGPCLLVSLYSYKSINNTYVRDAVDKNSYLLQMEKLHILNQIEAMER 87 L ++ I I+ P +++S+ ++++ + +++ V + HI +E Sbjct: 13 LNHKITILIIGTIVIPMVILSVLLFQNMRESVIKEKVKNVEISINQSYNHIQKNVELCHM 72 Query: 88 AAQMAYSDKAVQNYLL---NEHDPSLGELIDFNTTTFMNLSRIQINNPNIEHLRLYSGSG 144 + Q+ + + + L+ N D E+I F+ N+ R+ +NP + +R+Y G+ Sbjct: 73 STQVILNSEGFWDKLIEFQNSEDVDKNEIIKFSKNDVRNIERLVNSNPYLYQIRIYIGTK 132 Query: 145 EVHELWPIIFREERVSMEPWFQKALKLEGQELWSFQNEDPDLMQRYSGDPPKGQPKVSLL 204 +V E+ P+++ +R+ + W+ + + W+F + D + Y P K VSL Sbjct: 133 KVPEMMPVLYYMDRLEVFDWYDE--NDTRKIFWNF-DYDGTIFPYYVLKPSKHI--VSLT 187 Query: 205 REISIPAGHHVGMIQVDMLLSRFTPKTYTDVRDNQSQMFIAGEDLQLFTRADHSFVQDNP 264 + +I+V + P Y + + Q F+ + D + Q Sbjct: 188 TRVIATKKKVDALIEVATKMDVIFPDIY-EANEEQWTCFVDEHGTYFYGEGDSN--QKWL 244 Query: 265 QLTGAIAGRLQQYAETGEWDIHYKEKGNSFLLIHTPLTEIGASLVNVVSMEGVMKDISHT 324 + + +Q+ + + Y +K ++ + PL + L+ +VS++ +DI+ Sbjct: 245 EFAEGVFKTIQKDTKESYYHNMYLDK-EPVVVGYIPLEQFNGHLLKIVSLKKAFRDINDK 303 Query: 325 RNL-IIGLNIGFIVLVTAIAYVLNAFILKNLRRLTETMKKARRGEAYTGFSIRGGGEVGE 383 RN+ ++G + +L+ A A L +L++ R+ T+ K + G+ + E+G+ Sbjct: 304 RNVFLVGFSGAVAILIVA-ANFLVKLVLRDFYRVIHTVTKVKEGDLAIRVPVCSSNEIGQ 362 Query: 384 LAHHFSKLMNTINTLVAQAVNKEALSKEAELRTLHNQIDAHFLYNTLENIKMLAEIENQR 443 L+ + +M+TI L+ + +E L K++E+R L NQI+AHF+YN LE+IKM+AEIE + Sbjct: 363 LSGQINDMMDTITDLMEGQLKRELLVKDSEIRALQNQINAHFIYNVLESIKMMAEIEERY 422 Query: 444 GISDALTSLGGMMRYNFKWSGEYVKLRDEIRHIENYIEVMNIRFEYPILLELEVDAPYLE 503 ISDA+TSLG ++RY+ KW + V +R+E+ +I+NY+ ++N+RF+Y I L + + Sbjct: 423 DISDAVTSLGKLLRYSMKWVSKNVTVREEVDYIKNYLALINLRFDYEIYLSINMPDIIWS 482 Query: 504 LEVLKMSLQPVVENSVKHAWAAGEEELQNRSIRIQISEADGDIFIAIRDNGFGLTPERLT 563 E+ KMSLQP++EN++ H EE ++ SI ++ + I I D+G G+T E + Sbjct: 483 QEIPKMSLQPIIENAIYHGI---EEIAEDTSIYMKGILFEDYCTIEITDSGKGMTEEEVR 539 Query: 564 ELHSSIYAKEEPGADASXXXXXXXXXXXXXLRNVHQRLQLFYGEAYGLEVQSQAGEWTTV 623 +L I + E + L+NV R+++ +GE YG+ V S+ +T V Sbjct: 540 KLQRKISGEIETSGSSG---------NGIGLKNVQDRIKISFGEPYGISVASRKDCYTKV 590 Query: 624 FMTLPKVL 631 + +P +L Sbjct: 591 IVKIPLIL 598 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,581,530,941 Number of extensions: 146702023 Number of successful extensions: 406350 Number of sequences better than 1.0e-05: 1830 Number of HSP's gapped: 403593 Number of HSP's successfully gapped: 1831 Length of query: 638 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 496 Effective length of database: 1,722,912,073 Effective search space: 854564388208 Effective search space used: 854564388208 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 135 (56.6 bits)