BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0105.0010.p (194 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DBA0.1 B1DBA0_9BACL Putative transcriptional regulator, TetR f... 203 6e-51 B1HX05.1 B1HX05_LYSSC Transcriptional regulator, TetR family 113 8e-24 A3I7U0.1 A3I7U0_9BACI Transcriptional regulator, TetR family pro... 112 2e-23 C2QI42.1 C2QI42_BACCE Transcriptional regulator, TetR 111 4e-23 C2YXD7.1 C2YXD7_BACCE Transcriptional regulator, TetR 109 1e-22 >B1DBA0.1 B1DBA0_9BACL Putative transcriptional regulator, TetR family Length = 200 Score = 203 bits (517), Expect = 6e-51, Method: Compositional matrix adjust. Identities = 95/177 (53%), Positives = 138/177 (77%), Gaps = 1/177 (0%) Query: 17 ELLKDAVVELMEEMNVQKISVNRIAERAKINRVTFYLHYKDIPDMLEKMADEMVEDITRV 76 +LL+DA ++L+EEM+++KISVN++AERA INRVTFYLHYKDIPDMLEKMAD+M+ DI +V Sbjct: 17 QLLRDAFIDLLEEMDIEKISVNKLAERATINRVTFYLHYKDIPDMLEKMADDMIVDINQV 76 Query: 77 VNSNAAGNSEPGEHEDWPVLENLLKYIAENARFYKTVLTSRRSSIFSDRLFNLIADMIAA 136 ++ + + P E + +L LL++IAE+A+FYK +L S R++IF++RL L+ +I+ Sbjct: 77 LDRSTVKSDSP-EVINTTMLVKLLEHIAEHAKFYKIILASHRTTIFTERLLRLLTKLISD 135 Query: 137 RVERGVSAADTSQVSIQKDIATWYGSAALIGTIIAWLRNDMPYTPSYLAKQITSLRS 193 +++ + + ++ +IQKDIA WY SAALIGTI++WLR DMPYTP +LAKQ LR+ Sbjct: 136 GIDKRGNDSFVAKANIQKDIAVWYSSAALIGTIVSWLRADMPYTPVFLAKQFFLLRT 192 >B1HX05.1 B1HX05_LYSSC Transcriptional regulator, TetR family Length = 204 Score = 113 bits (283), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 59/182 (32%), Positives = 107/182 (58%), Gaps = 6/182 (3%) Query: 17 ELLKDAVVELMEEMNVQKISVNRIAERAKINRVTFYLHYKDIPDMLEKMADEMVEDITRV 76 +LL+DA+VEL++E +KI+V I +RA +NR TFYLHY+D D+L + ++E++ ++ Sbjct: 14 QLLRDALVELIDEQGYEKITVQDITQRATLNRATFYLHYRDKLDLLYQSSEEILHELVGS 73 Query: 77 VNSNAAGNSEPG--EHEDWP--VLENLLKYIAENARFYKTVLTSRRSSIFSDRLFNLIAD 132 ++ + H D P +L + IA N++ YK LT + FS L +I D Sbjct: 74 IHPTVEEKKDFDLLPHYDQPHETFMHLFEQIALNSKLYKVYLTEKDIPYFSAGLKKIIID 133 Query: 133 MIAARVERGVSAADTSQVSIQKDIATWYGSAALIGTIIAWLRNDMPYTPSYLAKQITSLR 192 +++ ++ + D ++++ +++A + +AA + I+ WL NDMPYTP ++A Q+ + Sbjct: 134 FVSSGIQ--LMEPDDQKLTVPREMAIRFYAAAFLEVIVWWLENDMPYTPKFMATQLMRIT 191 Query: 193 SK 194 K Sbjct: 192 IK 193 >A3I7U0.1 A3I7U0_9BACI Transcriptional regulator, TetR family protein Length = 204 Score = 112 bits (280), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 59/182 (32%), Positives = 107/182 (58%), Gaps = 6/182 (3%) Query: 17 ELLKDAVVELMEEMNVQKISVNRIAERAKINRVTFYLHYKDIPDMLEKMADEMVEDITRV 76 +LL+DA+VEL++E +KI+V I +RA +NR TFYLHY+D D+L + ++E++ ++ Sbjct: 14 QLLRDALVELIDEQGYEKITVQDITQRATLNRATFYLHYRDKLDLLYQSSEEILHELVGS 73 Query: 77 VNSNAAGNSEPG--EHEDWP--VLENLLKYIAENARFYKTVLTSRRSSIFSDRLFNLIAD 132 ++ + H D P +L + IA N++ YK LT + FS L +I D Sbjct: 74 IHPTFEEKRDFDLLPHYDQPHETFMHLFEQIALNSKLYKVYLTEKDIPYFSAGLKKIIID 133 Query: 133 MIAARVERGVSAADTSQVSIQKDIATWYGSAALIGTIIAWLRNDMPYTPSYLAKQITSLR 192 +++ ++ + D ++++ +++A + +AA + I+ WL NDMPYTP ++A Q+ + Sbjct: 134 FVSSGIQ--LMEPDDQKLTVPREMAIRFYAAAFLEVIVWWLENDMPYTPKFMATQLMRIT 191 Query: 193 SK 194 K Sbjct: 192 IK 193 >C2QI42.1 C2QI42_BACCE Transcriptional regulator, TetR Length = 205 Score = 111 bits (277), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 61/177 (34%), Positives = 97/177 (54%), Gaps = 4/177 (2%) Query: 17 ELLKDAVVELMEEMNVQKISVNRIAERAKINRVTFYLHYKDIPDMLEKMADEMVEDITRV 76 +L++DA V L+ E + ++V IAERA +NR TFY HY D D+LEK +EM+E +T V Sbjct: 16 QLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLEKSIEEMLEKLTEV 75 Query: 77 VNSNAAGNSEPGEHEDW--PVLENLLKYIAENARFYKTVLTSRRSSIFSDRLFNLIADMI 134 + E D P L ++IAEN FY +L + + FS ++ I + Sbjct: 76 IKPKNKNKEEFQLTFDSPNPTFLALFEHIAENVNFYNVMLGDKAAGNFSYKMMKTIQTHL 135 Query: 135 AARVERGVSAADTSQVSIQKDIATWYGSAALIGTIIAWLRNDMPYTPSYLAKQITSL 191 + +S + +++ + +DI Y + A IG I++WL+ M YTP ++A Q+T L Sbjct: 136 TLSL--SISQPNDTELMVPRDILISYVTGAHIGMIMSWLKRGMIYTPHFMAMQLTRL 190 >C2YXD7.1 C2YXD7_BACCE Transcriptional regulator, TetR Length = 205 Score = 109 bits (273), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 61/177 (34%), Positives = 96/177 (54%), Gaps = 4/177 (2%) Query: 17 ELLKDAVVELMEEMNVQKISVNRIAERAKINRVTFYLHYKDIPDMLEKMADEMVEDITRV 76 +L++DA V L+ E + ++V IAERA +NR TFY HY D D+L+K +EM+E +T V Sbjct: 16 QLIQDAFVALVGEKGFENVTVQHIAERAPVNRATFYSHYHDKYDLLDKSIEEMLEKLTEV 75 Query: 77 VNSNAAGNSEPGEHEDW--PVLENLLKYIAENARFYKTVLTSRRSSIFSDRLFNLIADMI 134 + E D P L ++IAENA FY +L + + +S ++ I + Sbjct: 76 IKPKNRNKEEFQLTFDSPNPTFLALFEHIAENANFYNVMLGDKAAGNYSYKMMKTIQTHL 135 Query: 135 AARVERGVSAADTSQVSIQKDIATWYGSAALIGTIIAWLRNDMPYTPSYLAKQITSL 191 + +S D + + +DI Y + A IG I++WL+ M YTP ++A Q+T L Sbjct: 136 TLSL--SISQPDDKDLMVPRDILISYVTGAHIGMIMSWLKRGMIYTPHFMAMQLTRL 190 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.130 0.365 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 892,943,773 Number of extensions: 30911137 Number of successful extensions: 117240 Number of sequences better than 1.0e-05: 487 Number of HSP's gapped: 116971 Number of HSP's successfully gapped: 487 Length of query: 194 Length of database: 3,060,696,203 Length adjustment: 128 Effective length of query: 66 Effective length of database: 1,854,806,283 Effective search space: 122417214678 Effective search space used: 122417214678 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 127 (53.5 bits)