BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0091.0003.p (200 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K7L0.1 B3K7L0_9BACI Low molecular weight phosphotyrosine prote... 243 5e-63 B1DEI9.1 B1DEI9_9BACL Protein tyrosine phosphatase 213 8e-54 Q8EM70.1 Q8EM70_OCEIH Protein-tyrosine-phosphatase EC=3.1.3.48 120 5e-26 A8VSN1.1 A8VSN1_9BACI Protein tyrosine phosphatase 117 5e-25 C0Z822.1 C0Z822_BREBN Low molecular weight protein-tyrosine-phos... 116 1e-24 >B3K7L0.1 B3K7L0_9BACI Low molecular weight phosphotyrosine protein phosphatase Length = 195 Score = 243 bits (621), Expect = 5e-63, Method: Compositional matrix adjust. Identities = 119/191 (62%), Positives = 148/191 (77%) Query: 6 MLHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEG 65 M +ILFVCTGNTCRSPMAEG+LRKLAK+RGI +E +SAGVSA+ G +SRHA +ILRD+ Sbjct: 1 MKNILFVCTGNTCRSPMAEGMLRKLAKQRGIPLETQSAGVSAVDGMPVSRHAESILRDQD 60 Query: 66 IHDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEAVNADI 125 I D+++S L A V WADL+LTLT HK++ ++ FP A K +TLKE+V D+ V D+ Sbjct: 61 IQDRLVSKPLTANLVEWADLILTLTQSHKQYAIRQFPHAADKMHTLKEFVEDDRRVLDDL 120 Query: 126 RELDSLYADAELSLALGGEPKSADLQRIIEIRQRIPSFDISDPFGGPREDYELAAAEIRT 185 RE DSLYA EL+ +LG + D +R+IE+RQRIPSFDISDPFGG RE+YE AAEIRT Sbjct: 121 REQDSLYATLELARSLGRDVSDRDRERLIELRQRIPSFDISDPFGGSREEYEATAAEIRT 180 Query: 186 ALHSLLDKLES 196 AL LLDKLE+ Sbjct: 181 ALFRLLDKLEA 191 >B1DEI9.1 B1DEI9_9BACL Protein tyrosine phosphatase Length = 192 Score = 213 bits (542), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 102/190 (53%), Positives = 133/190 (70%) Query: 6 MLHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEG 65 M ILFVCTGNTCRSPMAE +LR +A+++G+ +EVRSAGVS I G +S HAA LR + Sbjct: 1 MTRILFVCTGNTCRSPMAEAMLRTMARQKGVSLEVRSAGVSTIDGLPISSHAATTLRGKS 60 Query: 66 IHDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEAVNADI 125 + + S L+ E +AWADL+LT+T GHKR LL YFP+AV K YTLKEYV + AV ADI Sbjct: 61 VEHRGSSRALSGEAIAWADLILTMTAGHKRGLLNYFPEAVDKAYTLKEYVNQDTAVQADI 120 Query: 126 RELDSLYADAELSLALGGEPKSADLQRIIEIRQRIPSFDISDPFGGPREDYELAAAEIRT 185 EL+ LY + + LG + +A+ R++E+ +RIPSFDI+DPFGG YE A EI Sbjct: 121 EELERLYTEMHMKQVLGQQLSAAERSRLLELERRIPSFDIADPFGGTLGMYESCAKEIEE 180 Query: 186 ALHSLLDKLE 195 +L +LL L+ Sbjct: 181 SLKALLQMLQ 190 >Q8EM70.1 Q8EM70_OCEIH Protein-tyrosine-phosphatase EC=3.1.3.48 Length = 200 Score = 120 bits (302), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 76/204 (37%), Positives = 105/204 (51%), Gaps = 23/204 (11%) Query: 7 LHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEGI 66 +++LF+CTGNTCRSPMAEGLL K + V+SAG +A+ + S H L ++GI Sbjct: 1 MNVLFICTGNTCRSPMAEGLL----KSKMPAFNVKSAGTAAMDRSPASNHTMQALSEKGI 56 Query: 67 HDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEAVNADIR 126 S +N E + WAD+VLT+T HK+ L+ FP+ +K +TLKEYV EA Sbjct: 57 DMHHYSQSVNEELLEWADIVLTMTTSHKQSLIIQFPEQQSKYFTLKEYV--SEADKEIWG 114 Query: 127 ELDSLYADAELSLALG-------------GEPKSADLQRIIEIRQRIPS----FDISDPF 169 ++ YAD E AL + S + Q I QR+ S +DISDPF Sbjct: 115 QIQKAYADLEEKRALFIQKHQHMMNNFQLHQSVSKEFQTEINEIQRLESKLINYDISDPF 174 Query: 170 GGPREDYELAAAEIRTALHSLLDK 193 GG + Y EI + + K Sbjct: 175 GGGLDQYRNTMKEIEDCIDLFVQK 198 >A8VSN1.1 A8VSN1_9BACI Protein tyrosine phosphatase Length = 217 Score = 117 bits (294), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 82/217 (37%), Positives = 113/217 (52%), Gaps = 29/217 (13%) Query: 6 MLHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEG 65 M +LF+CTGNTCRSPMAE LL K+ D+ SAG+ + G MS +L+ G Sbjct: 1 MTKVLFICTGNTCRSPMAEALLEH--KKTDEDIVADSAGLHGVEGMPMSEGTRRVLQTRG 58 Query: 66 IHDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDE------- 118 I + S L+ + ADLVLT+T HKR L++++P+AV K YTLKEY D Sbjct: 59 IMESHQSRVLDEGQLRSADLVLTMTEHHKRSLIEHYPEAVDKVYTLKEYTADHSEMSQKM 118 Query: 119 ---------------EAVNADIRELDSLYADAELSLALGGEPKSADL-----QRIIEIRQ 158 E +NA+ R + + D E+S E + D I +++ Sbjct: 119 DQIKQEEAEMDLKRSEILNANERNVRAYNKDGEISGQTELEEELLDALMPYQSNIDKLKW 178 Query: 159 RIPSFDISDPFGGPREDYELAAAEIRTALHSLLDKLE 195 +PS DI+DPFGG E+YE A EI A+ LL K+E Sbjct: 179 DMPSLDIADPFGGGDEEYEAAYEEINHAVEQLLKKIE 215 >C0Z822.1 C0Z822_BREBN Low molecular weight protein-tyrosine-phosphatase EC=3.1.3.48 Length = 156 Score = 116 bits (291), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 73/197 (37%), Positives = 99/197 (50%), Gaps = 48/197 (24%) Query: 6 MLHILFVCTGNTCRSPMAEGLLRKLAKERGIDVEVRSAGVSAISGTSMSRHAAAILRDEG 65 M ILFVCTGNTCRSPMAE + R AK G +E+RSAGV+A +G S HA +L + G Sbjct: 1 MKRILFVCTGNTCRSPMAEAIFR--AKSDGQGLEIRSAGVAASAGQDASLHAKQVLEERG 58 Query: 66 IHDQILSTQLNAETVAWADLVLTLTGGHKRHLLQYFPDAVAKTYTLKEYVYDEEAVNADI 125 I +++++ + W+D++LT+T GHKR +L YFP A K +TL+E+V Sbjct: 59 IAHDHKASKVDEGLIEWSDVILTMTHGHKRAILTYFPSATEKVHTLQEFV---------- 108 Query: 126 RELDSLYADAELSLALGGEPKSADLQRIIEIRQRIPSF-DISDPFGGPREDYELAAAEIR 184 I F DI+DP+GG DY A EI Sbjct: 109 ---------------------------------GIEGFSDIADPYGGSLMDYRRCAEEIE 135 Query: 185 TALH--SLLDKLESLRR 199 +L SL+ K LR+ Sbjct: 136 ESLERLSLMLKDPGLRK 152 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,128,553,813 Number of extensions: 43367049 Number of successful extensions: 129923 Number of sequences better than 1.0e-05: 461 Number of HSP's gapped: 130031 Number of HSP's successfully gapped: 461 Length of query: 200 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 71 Effective length of database: 1,845,385,268 Effective search space: 131022354028 Effective search space used: 131022354028 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)