BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0088.0018.p (368 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A8W114.1 A8W114_9BACI Response regulator receiver protein 203 2e-50 B7DQ24.1 B7DQ24_9BACL Diguanylate cyclase 187 2e-45 C1PUV7.1 C1PUV7_ALIAC Diguanylate cyclase (GGDEF) domain-contain... 186 3e-45 A9U6K9.1 A9U6K9_PHYPA Predicted protein (Fragment) 186 4e-45 Q746Z1.1 Q746Z1_GEOSL GGDEF/response regulator receiver domain p... 129 3e-28 >A8W114.1 A8W114_9BACI Response regulator receiver protein Length = 368 Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 119/355 (33%), Positives = 193/355 (54%), Gaps = 5/355 (1%) Query: 10 RQAKWIKRFLQTYWLVIALHFLAQLAAYTFLPYERGAHEFY---YGVLLYPTLLMGAVVG 66 + ++WI + L+ YW +I + +A++ A T + EF+ VL+YPT+ ++ Sbjct: 12 KHSEWIDKTLRYYWYLIFIAIVAEIFALT-VTLIMSPSEFWDDVLPVLVYPTVAQVILLL 70 Query: 67 IAQWIDRRASKYSFISLFMAGTIIAMIIIHLNMDIRIIGALMLLPIFASAIFYRLDLTFF 126 I I ++ + L + G+++A I+I N + ++LLP+ S +F+ ++ F Sbjct: 71 ITTVIYKKKITENEYILMVVGSLLAFILIAANTSLAGAPLILLLPMMISILFFNKNVVIF 130 Query: 127 TFALQAVAFFVMYRWDYWFKYFFSSFDLIAIPIFLVVGTLVASIMIINGRELVSDLEASL 186 ++ + +A+ V + ++ IA G ++ + E++ L + Sbjct: 131 SYLVNVIAYLVTIALFPDLGEYLRIYEFIAYIYIFSAGFIILLAVQERSDEVIELLRKKV 190 Query: 187 MAKQDLLIENAVMRKLSTTDALTDLYNHISFHEFYDKALEYGDQGA-PFHLALIDIDNFK 245 +Q+L++ N +M +LS DA T LYNH +F E+ E + F LA++DIDNFK Sbjct: 191 DQEQELMVRNTIMERLSKVDAPTGLYNHKTFQEYLAYLFEQSSTSSYRFQLAMLDIDNFK 250 Query: 246 LINDKYGHRAGDIILARVAKVIRDLISSADIAARYGGEEFAILFFEKTFEEAEAIADKIR 305 +ND YGH GD IL R+A +I+ + + DIA+RYGGEEF +LF + +FE A + + IR Sbjct: 251 QVNDTYGHAVGDKILERIAGIIQANVDANDIASRYGGEEFGVLFTDCSFETALHVVETIR 310 Query: 306 LRLSGTPHEEMDGAAVTVSIGLKSYSQGTTKEQLFEEVDALLYAAKHEGKNKVRT 360 L + PHEEM G VTVSIGL Y+ LFE+ D LLY AK GKN++ T Sbjct: 311 LEIERLPHEEMGGRNVTVSIGLVEYTDEEQAPVLFEKADTLLYLAKKNGKNRIET 365 >B7DQ24.1 B7DQ24_9BACL Diguanylate cyclase Length = 376 Score = 187 bits (474), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 123/367 (33%), Positives = 192/367 (52%), Gaps = 16/367 (4%) Query: 3 PSGTSAYRQAKWIKRFLQTYWLVIALHFLAQLAAYTFLPYERGAHEFYYGVL-----LYP 57 P +R +R +Q + L +AL FLA FLP E H + L ++ Sbjct: 6 PEDVREFRNGA--QRAIQIHRLFVAL-FLA--GDLLFLPGEWWLHRAHLLPLALRAWMFA 60 Query: 58 TLLMGAVVGIAQWIDRRASKYSFISLFMAGTIIAMIIIHLNMDIRIIGALMLLPIFASAI 117 +L+ ++ G A+W R+ + L +AGT++A++ I D + A +LLP+ S + Sbjct: 61 PILLVSIEGAAEWAVRKYPQSRENVLIVAGTLLALVAIAAYPDAEALRASLLLPVVTSIL 120 Query: 118 FYRLDLTFFT----FALQAVAFFVMYRWDYWFKYFFSSFDLIAIPIFLVVGTLVASIMII 173 R++ + FA + + + S +A+ +++ T A +++ Sbjct: 121 HLRVEKVWLAGAVAFAAELALTLMQMSGGASAEAILQSLGHLALWSLVLLWTTSACHIVL 180 Query: 174 N-GRELVSDLEASLMAKQDLLIENAVMRKLSTTDALTDLYNHISFHEFYDKALEYGD-QG 231 G + +L A+ +L + + K + TDALT LYN SF E+ D AL+ + Sbjct: 181 RFGLRIWDELRVQARAQTELWVRQILSEKEAKTDALTGLYNRKSFDEYLDFALQISEGTN 240 Query: 232 APFHLALIDIDNFKLINDKYGHRAGDIILARVAKVIRDLISSADIAARYGGEEFAILFFE 291 P HLA+IDIDNFK IND+YGH GD IL R A+ I+ +++ D ARYGGEEFA++ E Sbjct: 241 TPLHLAVIDIDNFKQINDRYGHLVGDEILRRTAQAIQQHLAAGDFLARYGGEEFAVIIPE 300 Query: 292 KTFEEAEAIADKIRLRLSGTPHEEMDGAAVTVSIGLKSYSQGTTKEQLFEEVDALLYAAK 351 + E+A +KIR ++ H E+DG TVSIGL ++ G T+++LFE D LY AK Sbjct: 301 VSHEQAVQNMEKIREYIANVHHLELDGNRATVSIGLSTHRPGETRDELFERADQCLYRAK 360 Query: 352 HEGKNKV 358 GKNK+ Sbjct: 361 QTGKNKI 367 >C1PUV7.1 C1PUV7_ALIAC Diguanylate cyclase (GGDEF) domain-containing protein Length = 402 Score = 186 bits (472), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 126/367 (34%), Positives = 189/367 (51%), Gaps = 16/367 (4%) Query: 3 PSGTSAYRQAKWIKRFLQTYWLVIALHFLAQLAAYTFLPYERGAHEFYYGVL-----LYP 57 P +R +R +Q + L +AL FLA FLP E H + L ++ Sbjct: 32 PEDVREFRNGA--QRAIQIHRLFVAL-FLA--GDLLFLPGEWWLHRAHLLPLALRAWVFA 86 Query: 58 TLLMGAVVGIAQWIDRRASKYSFISLFMAGTIIAMIIIHLNMDIRIIGALMLLPIFASAI 117 L M + G A+W R+ + L +GT++A++ I + A +LLPI S + Sbjct: 87 PLAMVCIQGAAEWSVRKHPQSRENMLIASGTLLALVAIAAYPGAESLCASLLLPIVTSIL 146 Query: 118 FYRLDLTFFTFAL----QAVAFFVMYRWDYWFKYFFSSFDLIAIPIFLVVGTLVASIMII 173 R++ + A + V + + S +A+ +++ T AS +++ Sbjct: 147 HLRVEKVWLAGAAAFAAELVLTLMQLSSSASAQAILQSLGHLALWSLILLWTTAASHIVL 206 Query: 174 N-GRELVSDLEASLMAKQDLLIENAVMRKLSTTDALTDLYNHISFHEFYDKALEYGD-QG 231 G + +L A+ +L + + K + TDALT LYN SF E+ D AL+ D Sbjct: 207 RFGLRIWDELRVQTRAQTELWVRQILSEKEAKTDALTGLYNRKSFDEYLDFALQISDGTN 266 Query: 232 APFHLALIDIDNFKLINDKYGHRAGDIILARVAKVIRDLISSADIAARYGGEEFAILFFE 291 P HLA+IDIDNFK IND+YGH GD IL R A+ I+ +++ D ARYGGEEFA++ E Sbjct: 267 TPLHLAVIDIDNFKQINDQYGHLVGDEILRRTAQAIQQHLAAGDFLARYGGEEFAVIIPE 326 Query: 292 KTFEEAEAIADKIRLRLSGTPHEEMDGAAVTVSIGLKSYSQGTTKEQLFEEVDALLYAAK 351 T E+A +KIR ++ H E+DG TVSIGL ++ G T+++LFE D LY AK Sbjct: 327 VTHEQAVQNMEKIREYIANVHHVELDGNRATVSIGLSTHRPGETRDELFERADQCLYRAK 386 Query: 352 HEGKNKV 358 GKNK+ Sbjct: 387 QTGKNKI 393 >A9U6K9.1 A9U6K9_PHYPA Predicted protein (Fragment) Length = 866 Score = 186 bits (471), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 102/256 (39%), Positives = 152/256 (59%), Gaps = 7/256 (2%) Query: 108 MLLPIFASAIFYRLDLTFFTFALQAVAFFVMYRWDYWFKYFFSSFDLIAIPIFLVVGTLV 167 +LLP+ S +++ L + +L + + ++Y + Y + I I +V ++ Sbjct: 3 LLLPVLISVVYFDRKLLYGFGSLTILLYCLIYLTERSL-YQKPIQEFIQIQSVFIVSIMI 61 Query: 168 ASIMIINGRELVSDLEASLMAKQDLLIENAVMRKLSTTDALTDLYNHISFHEFYDKALEY 227 +++ +E + LE+ + ++Q LL+E + KL DALT LYNH +FHE+ + LE Sbjct: 62 GHTILVRVKEFMRHLESVMKSEQQLLVERTISDKLLKIDALTGLYNHKAFHEYLEALLEQ 121 Query: 228 GDQ-GAPFHLALIDIDNFKLINDKYGHRAGDIILARVAKVIRDLISSADIAARYGGEEFA 286 ++ P LA+IDIDNFK +ND YGHR GD++L VA + ++ D AARYGGEEFA Sbjct: 122 CEKYQLPLQLAIIDIDNFKKVNDNYGHRVGDVVLKEVASKVMSTMTPNDFAARYGGEEFA 181 Query: 287 ILFFEKTFEEAEAIADKIRLRLSGT--PHEEMDGAAVTVSIGLKSYSQGTTKEQLFEEVD 344 I+ +KT EEAE +A+++R R++ T PH VTVSIGL ++ QG KE LF + D Sbjct: 182 IIMADKTLEEAERMAEQLRERIARTELPH---TVKPVTVSIGLCNFQQGDDKESLFRKAD 238 Query: 345 ALLYAAKHEGKNKVRT 360 LY AK GKNKV T Sbjct: 239 MALYQAKRTGKNKVVT 254 >Q746Z1.1 Q746Z1_GEOSL GGDEF/response regulator receiver domain protein Length = 308 Score = 129 bits (325), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 80/202 (39%), Positives = 115/202 (56%), Gaps = 19/202 (9%) Query: 177 ELVSDLEASLMAK--QDLLIE-NAVMRKLSTTDALTDLYNHISFHEFYDKALEYGD-QGA 232 ELV+ + + K QD L N ++RKLS TD LT L+N E DK + +G Sbjct: 113 ELVARVRVQMKVKGLQDELKRSNELLRKLSITDPLTHLHNRRHLMEMVDKEFQRASRKGG 172 Query: 233 PFHLALIDIDNFKLINDKYGHRAGDIILARVAKVIRDLISSADIAARYGGEEFAILFFEK 292 L ++DID FK IND YGH+ GD +L +A ++R + S D+AARYGGEEF +L E Sbjct: 173 ALSLVILDIDYFKKINDTYGHQEGDKVLVALADIVRLRLRSYDVAARYGGEEFVLLLPET 232 Query: 293 TFEEAEAIADKIRLRLS-----GTPHEEMDGAAVTVSIGLKSYS----QGTTKEQLFEEV 343 +EA+AIA+++RL + G+ H G +T+S+G+ +Y +GT + LF + Sbjct: 233 PLQEAQAIAERLRLEVQDHVFDGSLH----GQVITISLGVATYPSPRIEGT--DSLFRQA 286 Query: 344 DALLYAAKHEGKNKVRTPYSST 365 D LY AK G+N+V ST Sbjct: 287 DEALYRAKQNGRNRVELMSGST 308 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.327 0.141 0.414 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,037,869,794 Number of extensions: 81227581 Number of successful extensions: 320971 Number of sequences better than 1.0e-05: 13841 Number of HSP's gapped: 311885 Number of HSP's successfully gapped: 13857 Length of query: 368 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 231 Effective length of database: 1,770,017,148 Effective search space: 408873961188 Effective search space used: 408873961188 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 132 (55.5 bits)