BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0078.0027.p (595 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9VPX9.1 A9VPX9_BACWK ABC transporter related 635 e-180 C2UYQ8.1 C2UYQ8_BACCE ABC transporter 626 e-177 C2X1P0.1 C2X1P0_BACCE ABC transporter 625 e-177 C2U0X0.1 C2U0X0_BACCE ABC transporter 625 e-177 B3Z5G8.1 B3Z5G8_BACCE Lipid A export ATP-binding/permease protei... 622 e-176 >A9VPX9.1 A9VPX9_BACWK ABC transporter related Length = 599 Score = 635 bits (1637), Expect = e-180, Method: Compositional matrix adjust. Identities = 306/594 (51%), Positives = 425/594 (71%), Gaps = 3/594 (0%) Query: 1 MYYIRQLQRLSGVKLYLNLLGMVISGLLESSAVLLLVPMLGMAGIQLGGNAAGIDLPMLD 60 +Y++++L +G LY+NL GMV+ LLE ++LL+PM+ MAGI G A P+ Sbjct: 5 IYFMKKLYSSAGKILYVNLFGMVLISLLEGIGIILLIPMISMAGIINIGEEAAFIAPVYR 64 Query: 61 FISELPQTSALALVLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYEVYGALLRAEW 120 F+ + P+T++L +LG Y+LIVL QNL+ R + +R+ QQ++ R+LR E Y +L+A+W Sbjct: 65 FLQDFPKTTSLISILGIYILIVLGQNLLQRNITLRDARTQQAFVRELRIETYNMILKAKW 124 Query: 121 SFFLKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLSPQMTXXXXXX 180 SFFL+KR ++LIN++TTELARV G+ +Q+G AF LSPQ+T Sbjct: 125 SFFLEKRKTNLINILTTELARVSYGVNLILQLLAVILFTFIQVGLAFLLSPQITIFVLVF 184 Query: 181 XXXXXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEGSRLSWMHEFT 240 SR FI+KA+ LG ++S+L + YL+GITD NGIKDIKSN LE SRL W+ T Sbjct: 185 GLLFLVASRAFIKKARILGGKTSKLAQDYLSGITDHFNGIKDIKSNTLEASRLDWLQSIT 244 Query: 241 DEVKKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLVILVFARLWPT 300 +++ EQ++Y R+R+NSQL YK+S +LIA FI +S + LLL+IL+F+RLWP Sbjct: 245 EKMSNEQMEYMRIRSNSQLFYKVSMAILIAFFILLSVSIFKAQPTQLLLIILIFSRLWPR 304 Query: 301 FSSLQTLLEQLASVLPSFK-IXXXXXXXXXXXXXHGAHGESGVVPAPMALKHGLEARDVN 359 F ++Q+ LEQLA+ +P+FK + H + + P+ ++ G+E + + Sbjct: 305 FMTIQSNLEQLAASIPAFKSLWDLQGECNEAIEMQDIHQQKHI--KPICIEQGIECKGIY 362 Query: 360 FRYNPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPV 419 FRYN +E Y+L+ ++V IP N MTAIVG SGAGKSTL+D+LMGL+QPE G++L DG P+ Sbjct: 363 FRYNKKEHLYALQNINVKIPINSMTAIVGHSGAGKSTLIDVLMGLIQPEKGQVLIDGTPL 422 Query: 420 TGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQ 479 T E LL RR+I YV QDPFL+NA+IR+NL MI+P+ASE ++W AL+FA++A+FVR LP+ Sbjct: 423 TSENLLSLRRAISYVPQDPFLFNASIRENLLMIEPNASEEQIWTALDFAAAAEFVRMLPK 482 Query: 480 GLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKA 539 GLDTL+GDRGVRLSGGERQRLVLARAI+R+PSILVLDEATSALDTENE +IQ A+ERLK Sbjct: 483 GLDTLIGDRGVRLSGGERQRLVLARAILRQPSILVLDEATSALDTENEVKIQSAIERLKG 542 Query: 540 TVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQEE 593 T+T++VIAHRLSTIR ADQ++V+ +G ++Q+G ++ LA E+ G+F LL SQ E Sbjct: 543 TMTIVVIAHRLSTIRNADQVIVLGKGEIVQKGEFNQLAKERKGVFRNLLGSQME 596 >C2UYQ8.1 C2UYQ8_BACCE ABC transporter Length = 592 Score = 626 bits (1615), Expect = e-177, Method: Compositional matrix adjust. Identities = 306/592 (51%), Positives = 414/592 (69%), Gaps = 3/592 (0%) Query: 4 IRQLQRLSGVKLYLNLLGMVISGLLESSAVLLLVPMLGMAGIQLGGNAAGIDLPMLDFIS 63 +++L +G LY+NL GMV+ LLE ++LL+PM+ M GI G P+ + Sbjct: 1 MKKLYSSAGKILYVNLFGMVLISLLEGIGIILLLPMISMTGIINTGEETSFIAPVYRILQ 60 Query: 64 ELPQTSALALVLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYEVYGALLRAEWSFF 123 + P+T++L +LG YVLIVL QN++ R + +R+ QQ + R+LR E Y +L+A+W FF Sbjct: 61 DFPKTTSLISILGIYVLIVLSQNILQRNITLRDARTQQVFVRKLRVETYSMILKAKWRFF 120 Query: 124 LKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLSPQMTXXXXXXXXX 183 L+KR ++LIN++TTELARV GI +Q+G AF LSPQ+T Sbjct: 121 LEKRKTNLINILTTELARVSYGINLILQLLATILFTFIQVGLAFLLSPQVTVFVLGFGLL 180 Query: 184 XXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEGSRLSWMHEFTDEV 243 SR FI+KA+ LG ++SEL K YL+GITD NGIKDIKSN LEGSRL W T ++ Sbjct: 181 FLVASRVFIKKARILGGKTSELAKDYLSGITDHFNGIKDIKSNTLEGSRLDWFQSITKKM 240 Query: 244 KKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLVILVFARLWPTFSS 303 EQ++Y R+R+NSQL YK+S +LIA FIF+S + LLL+IL+F+RLWP F + Sbjct: 241 SSEQMEYMRIRSNSQLFYKISMAILIAFFIFLSVNMFQAQTAQLLLIILIFSRLWPRFMT 300 Query: 304 LQTLLEQLASVLPSFK-IXXXXXXXXXXXXXHGAHGESGVVPAPMALKHGLEARDVNFRY 362 +Q+ LEQLA+ +P+FK + + + + P+ +K G+E +DV+FRY Sbjct: 301 IQSNLEQLAASIPAFKSLWELQQECNEAVEMQDIYMQKHI--KPICIKQGIECKDVSFRY 358 Query: 363 NPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPVTGE 422 N QE Y+L+ ++V IP N MTAIVG SGAGKSTL+D+LMGL+QPE G++L DG P+T + Sbjct: 359 NKQEALYALQNINVQIPINSMTAIVGHSGAGKSTLIDVLMGLIQPEKGQVLIDGIPLTTD 418 Query: 423 RLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQGLD 482 LL RR+I YV QDPFL+NA+IR+NL MI + +E ++W ALEFA++ +FVR LP GLD Sbjct: 419 NLLSLRRAISYVPQDPFLFNASIRENLMMIDSNVNEEQIWAALEFAAATEFVRMLPNGLD 478 Query: 483 TLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKATVT 542 TL+GDRGVRLSGGERQRLVLARAI+RKPSILVLDEATSALDTENE +IQ A+ERLK T+T Sbjct: 479 TLIGDRGVRLSGGERQRLVLARAILRKPSILVLDEATSALDTENEVKIQSAIERLKGTMT 538 Query: 543 VIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQEEA 594 ++VIAHRLSTIR ADQ++V+ +G ++Q+G ++ LA E+ G+F LL SQ E Sbjct: 539 IVVIAHRLSTIRNADQVIVLGKGEIVQKGEFNQLAKERKGVFRNLLGSQMEV 590 >C2X1P0.1 C2X1P0_BACCE ABC transporter Length = 592 Score = 625 bits (1611), Expect = e-177, Method: Compositional matrix adjust. Identities = 306/592 (51%), Positives = 411/592 (69%), Gaps = 3/592 (0%) Query: 4 IRQLQRLSGVKLYLNLLGMVISGLLESSAVLLLVPMLGMAGIQLGGNAAGIDLPMLDFIS 63 +++L +G LY+NL GMV+ LLE ++LL+PM+ M GI G P + Sbjct: 1 MKKLYSSAGKILYVNLFGMVLISLLEGIGIILLLPMISMTGIINTGEETSFIAPAYRILQ 60 Query: 64 ELPQTSALALVLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYEVYGALLRAEWSFF 123 P+T++L +LG YVLIVL QN++ R + +R+ QQ + R+LR E Y +L+A+W FF Sbjct: 61 NFPKTTSLISILGIYVLIVLSQNILQRNITLRDARTQQVFVRKLRVETYSMILKAKWRFF 120 Query: 124 LKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLSPQMTXXXXXXXXX 183 L+KR ++LIN++TTELARV GI +Q+G AF LSPQ+T Sbjct: 121 LEKRKTNLINILTTELARVSYGINLILQLLATILFTFIQVGLAFLLSPQVTVFVLGFGLL 180 Query: 184 XXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEGSRLSWMHEFTDEV 243 SR FI+KA+ LG ++SEL K YL+GITD NGIKDIKSN LEGSRL W T ++ Sbjct: 181 FLVASRVFIKKARILGGKTSELAKDYLSGITDHFNGIKDIKSNTLEGSRLDWFQSITKKM 240 Query: 244 KKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLVILVFARLWPTFSS 303 EQ++Y R+R+NSQL YK+S +LIA FIF+S + LLL+IL+F+RLWP F + Sbjct: 241 SSEQMEYMRIRSNSQLFYKISMAILIAFFIFLSVNMFQAQTAQLLLIILIFSRLWPRFMT 300 Query: 304 LQTLLEQLASVLPSFK-IXXXXXXXXXXXXXHGAHGESGVVPAPMALKHGLEARDVNFRY 362 +Q+ LEQLA+ +P+FK + + + + P+ +K G+E +DV+FRY Sbjct: 301 IQSNLEQLAASIPAFKSLWELQQECNEAVEMQDIYMQKHI--KPICIKQGIECKDVSFRY 358 Query: 363 NPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPVTGE 422 N QE Y+L+ ++V IP N MTAIVG SGAGKSTL+D+LMGL+QPE G +L DG P+T + Sbjct: 359 NKQEALYALQNINVQIPINSMTAIVGHSGAGKSTLIDVLMGLIQPEKGRVLIDGTPLTTD 418 Query: 423 RLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQGLD 482 LL RR+I YV QDPFL+NA+IR+NL MI + +E ++W ALEFA++ +FVR LP GLD Sbjct: 419 NLLSLRRAISYVPQDPFLFNASIRENLMMIDSNVNEEQIWAALEFAAATEFVRMLPNGLD 478 Query: 483 TLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKATVT 542 TL+GDRGVRLSGGERQRLVLARAI+RKPSILVLDEATSALDTENE +IQ A+ERLK T+T Sbjct: 479 TLIGDRGVRLSGGERQRLVLARAILRKPSILVLDEATSALDTENEVKIQSAIERLKGTMT 538 Query: 543 VIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQEEA 594 ++VIAHRLSTIR ADQ++V+ +G ++Q+G ++ LA E+ G+F LL SQ E Sbjct: 539 IVVIAHRLSTIRNADQVIVLGKGEIVQKGEFNQLAKERKGVFQNLLGSQMEV 590 >C2U0X0.1 C2U0X0_BACCE ABC transporter Length = 592 Score = 625 bits (1611), Expect = e-177, Method: Compositional matrix adjust. Identities = 305/592 (51%), Positives = 413/592 (69%), Gaps = 3/592 (0%) Query: 4 IRQLQRLSGVKLYLNLLGMVISGLLESSAVLLLVPMLGMAGIQLGGNAAGIDLPMLDFIS 63 +++L +G LY+NL GMV+ LLE ++LL+PM+ M GI G P+ + Sbjct: 1 MKKLYSSAGKILYVNLFGMVLISLLEGIGIILLLPMISMTGIINTGEETSFIAPVYRILQ 60 Query: 64 ELPQTSALALVLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYEVYGALLRAEWSFF 123 P+T++L +LG YVLIVL QN++ R + +R+ QQ + R+LR E Y +L+A+W FF Sbjct: 61 NFPKTTSLISILGIYVLIVLSQNILQRNITLRDARTQQVFVRKLRVETYSMILKAKWRFF 120 Query: 124 LKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLSPQMTXXXXXXXXX 183 L+KR ++LIN++TTELARV GI +Q+G AF LSPQ+T Sbjct: 121 LEKRKTNLINILTTELARVSYGINLILQLLATILFTFIQVGLAFLLSPQVTVFVLGFGLL 180 Query: 184 XXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEGSRLSWMHEFTDEV 243 SR FI+KA+ LG ++SEL K YL+GITD NGIKDIKSN LEGSRL W T ++ Sbjct: 181 FLVASRVFIKKARILGGKTSELAKDYLSGITDHFNGIKDIKSNTLEGSRLDWFQSITKKM 240 Query: 244 KKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLVILVFARLWPTFSS 303 EQ++Y R+R+NSQL YK+S +LIA FIF+S + LLL+IL+F+RLWP F + Sbjct: 241 SSEQMEYMRIRSNSQLFYKISMAILIAFFIFLSVNMFQAQTAQLLLIILIFSRLWPRFMT 300 Query: 304 LQTLLEQLASVLPSFK-IXXXXXXXXXXXXXHGAHGESGVVPAPMALKHGLEARDVNFRY 362 +Q+ LEQLA+ +P+FK + + + + P+ +K G+E +DV+FRY Sbjct: 301 IQSNLEQLAASIPAFKSLWELQQECNEAVEMQDIYMQKHI--KPICIKQGIECKDVSFRY 358 Query: 363 NPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPVTGE 422 N QE Y+L+ ++V IP N MTAIVG SGAGKSTL+D+LMGL+QPE G++L DG P+T + Sbjct: 359 NKQEALYALQNINVQIPINSMTAIVGHSGAGKSTLIDVLMGLIQPEKGQVLIDGTPLTTD 418 Query: 423 RLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQGLD 482 LL R++I YV QDPFL+NA+IR+NL MI + +E ++W ALEFA++ +FVR LP GLD Sbjct: 419 NLLSLRQAISYVPQDPFLFNASIRENLMMIDSNVNEEQIWAALEFAAATEFVRMLPNGLD 478 Query: 483 TLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKATVT 542 TL+GDRGVRLSGGERQRLVLARAI+RKPSILVLDEATSALDTENE +IQ A+ERLK T+T Sbjct: 479 TLIGDRGVRLSGGERQRLVLARAILRKPSILVLDEATSALDTENEVKIQSAIERLKGTMT 538 Query: 543 VIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQEEA 594 ++VIAHRLSTIR ADQ++V+ +G ++Q+G ++ LA E+ G+F LL SQ E Sbjct: 539 IVVIAHRLSTIRNADQVIVLGKGEIVQKGEFNQLAKERKGVFRNLLGSQMEV 590 >B3Z5G8.1 B3Z5G8_BACCE Lipid A export ATP-binding/permease protein MsbA EC=3.6.3.- Length = 593 Score = 622 bits (1603), Expect = e-176, Method: Compositional matrix adjust. Identities = 304/595 (51%), Positives = 415/595 (69%), Gaps = 9/595 (1%) Query: 1 MYYIRQLQRLSGVKLYLNLLGMVISGLLESSAVLLLVPMLGMAGIQLGGNAAGIDLPMLD 60 +Y++++L +G LY+NL GMV+ LLE ++LL+PM+ M GI G P+ Sbjct: 5 IYFMKKLYSSAGKILYVNLFGMVLISLLEGIGIILLIPMISMTGIINLGEETTFIAPVSR 64 Query: 61 FISELPQTSALALVLGAYVLIVLCQNLISRFVAIRNVDIQQSYSRQLRYEVYGALLRAEW 120 F+ + P+T++LA +LG Y+LIVL QNL+ R + +R+ QQ++ R+LR E Y +L+A+W Sbjct: 65 FLQDFPKTTSLAFILGIYILIVLGQNLLQRNITLRDARTQQAFVRELRIETYSMILKAKW 124 Query: 121 SFFLKKRTSDLINVMTTELARVLAGIXXXXXXXXXXXXXXVQIGFAFWLSPQMTXXXXXX 180 SFFL+KR ++LIN +TTELARV G+ +Q+G AF LSPQ+T Sbjct: 125 SFFLEKRKTNLINTLTTELARVSYGVNLILQLLAAILFTFIQVGIAFLLSPQITIFVLVF 184 Query: 181 XXXXXXFSRRFIRKAKRLGSRSSELGKQYLAGITDQLNGIKDIKSNNLEGSRLSWMHEFT 240 SR FI+KA+ LG ++SEL K YL+GITD NGIK+IKSN LE SRL W+ T Sbjct: 185 GLLFLVASRVFIKKARILGGKTSELAKDYLSGITDHFNGIKEIKSNTLESSRLDWLQSIT 244 Query: 241 DEVKKEQLDYTRLRTNSQLLYKMSSTLLIAMFIFVSFRFLHVEGPYLLLVILVFARLWPT 300 +++ EQ++Y R+R+NSQL YK+S +LIA F+ +S + LLL+IL+F+RLWP Sbjct: 245 EKMSNEQMEYMRIRSNSQLFYKVSMAILIAFFLLLSVSMFQAQSTQLLLIILIFSRLWPR 304 Query: 301 FSSLQTLLEQLASVLPSFK-IXXXXXXXXXXXXXHGAHGESGVVPAPMALKHGLEARDVN 359 F ++QT LEQLA+ +P+FK + G H + + P+ ++ G+E +DV+ Sbjct: 305 FMTIQTNLEQLAASVPAFKSLWELQEECKEAIEMQGIHQQKHI--KPICIEQGIECKDVH 362 Query: 360 FRYNPQEENYSLRGVDVVIPANRMTAIVGRSGAGKSTLVDLLMGLMQPESGEILADGEPV 419 FRYN QE Y+L+ ++V IP N MTAIVG SGAGKSTL+D+LMGL+QPE G++L DG P+ Sbjct: 363 FRYNKQESLYALQNINVQIPINSMTAIVGHSGAGKSTLIDVLMGLIQPEKGQVLIDGTPL 422 Query: 420 TGERLLPYRRSIGYVAQDPFLYNATIRDNLTMIKPDASEAELWEALEFASSADFVRKLPQ 479 T + LL RR+I YV QDPFL+NA+IR+NL MI+P+AS +W AL+FA++ +FVR LP Sbjct: 423 TTDNLLSLRRAISYVPQDPFLFNASIRENLLMIEPNASGEAIWAALDFAAATEFVRTLPN 482 Query: 480 GLDTLLGDRGVRLSGGERQRLVLARAIIRKPSILVLDEATSALDTENEKRIQEALERLKA 539 GLDTL+GDRGVRLSGGERQRLVLARAI+RKP ILVLDEATSALD ENE +IQ A+ERLK Sbjct: 483 GLDTLIGDRGVRLSGGERQRLVLARAILRKPLILVLDEATSALDIENEVKIQSAIERLKG 542 Query: 540 TVTVIVIAHRLSTIRGADQILVIDQGRVIQQGVYSGLASEKGGMFNRLLSSQEEA 594 T+T+IVIAHRLSTIR ADQ++V+ +G ++Q+G E+ G+F LL Q E Sbjct: 543 TMTIIVIAHRLSTIRNADQVIVLGKGEIVQKG------EERKGVFRNLLGKQVEV 591 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.138 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,996,192,250 Number of extensions: 115879298 Number of successful extensions: 629782 Number of sequences better than 1.0e-05: 92798 Number of HSP's gapped: 539624 Number of HSP's successfully gapped: 100292 Length of query: 595 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 453 Effective length of database: 1,722,912,073 Effective search space: 780479169069 Effective search space used: 780479169069 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)