BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0078.0020.p (297 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B7R8G7.1 B7R8G7_9THEO CAAX amino terminal protease family protein 110 1e-22 Q8RCK9.1 Q8RCK9_THETN Predicted metal-dependent membrane protease 108 5e-22 C2KS73.1 C2KS73_9ACTO Possible metal-dependent membrane protease 102 5e-20 B1DM63.1 B1DM63_9BACL Abortive infection protein 96 5e-18 B3QY90.1 B3QY90_CHLT3 Abortive infection protein 95 7e-18 >B7R8G7.1 B7R8G7_9THEO CAAX amino terminal protease family protein Length = 337 Score = 110 bits (275), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/273 (30%), Positives = 138/273 (50%), Gaps = 22/273 (8%) Query: 7 IFRNRKRQLRAGWELLLVAAAIFMLTMLMSF---------GLSLRVNSRQLF-----DPD 52 IF N+ Q+R+GW++ ++ A F++T+L+SF G L+ +++L+ + Sbjct: 39 IFVNKNGQMRSGWKITILIAGTFVITLLLSFLAFFIIGLIGGYLKYTAQKLYLLLMVGEE 98 Query: 53 GWVQVFKSSGLYMLXXXXXXXXXXXXQPLSTIGLT--RPDVKRFAQGLLSGALLMAIIVM 110 + S L + + IG T + K G L GA +AIIV+ Sbjct: 99 RFYLFTTISFLSTVIMITLMLKFIDKKKFKDIGFTSLKYGYKNLIVGFLIGAFSIAIIVL 158 Query: 111 VLWALGNAVFQ-NEGWTPRFSQLDLPGLVLTACIAGICEEALFRGYIQHLLTSRLGTVWA 169 +L+ LG + N + + + +L G+ EE + RGY + L + Sbjct: 159 ILYILGAVTIERNSNISAYYLLWGMYAFIL----VGLEEELMSRGYFINALNQMERPWVS 214 Query: 170 VVITSVLFSAAHMANPGYNWISALNIVLIALIFSWATLRAGNLYFAMALHLSWNLVQGYG 229 V+I+S++FS H+ NP ++ LNI LI ++FS+ L+ GNL+ + H+SWN QGY Sbjct: 215 VLISSIIFSLMHILNPNIVFLGLLNIFLIGVLFSYMYLKTGNLWMPIGYHISWNYFQGYI 274 Query: 230 FGVSVSGNIQQGLYSVMLEGPDWITGGSFGLEA 262 FG +VSGN +G+Y+ ++++GG FGLE Sbjct: 275 FGFNVSGNAIRGIYNA-FPKNNFLSGGDFGLEG 306 >Q8RCK9.1 Q8RCK9_THETN Predicted metal-dependent membrane protease Length = 302 Score = 108 bits (271), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 81/275 (29%), Positives = 134/275 (48%), Gaps = 20/275 (7%) Query: 4 MHYIFRNRKRQLRAGWELLLVAAAIFMLTMLMSF------GLSLRVNSRQLFD------- 50 M +F N+ Q+R+GW++ ++ A F++T+L +F GL + + + Sbjct: 1 MKKMFVNKNGQMRSGWKIAILIAGTFVITLLFAFLAFLIIGLIGKYSEYTMHKLLLLLMV 60 Query: 51 -PDGWVQVFKSSGLYMLXXXXXXXXXXXXQPLSTIGLT--RPDVKRFAQGLLSGALLMAI 107 + + S L L + IG T + K G L GA +AI Sbjct: 61 GEERFYLFTTISFLSTLIMIALMLKFIDKKKFKDIGFTSLKDGYKDLVAGFLIGAFSIAI 120 Query: 108 IVMVLWALGNAVFQNEGWTPRFSQLDLPGLVLTACIAGICEEALFRGYIQHLLTSRLGTV 167 IV++L+ +G + S L G + + G+ EE + RGY + L Sbjct: 121 IVLILYIIGAVTIERN---SNISAYYLLGGMYAFILVGLEEELMSRGYFINALNQMERPW 177 Query: 168 WAVVITSVLFSAAHMANPGYNWISALNIVLIALIFSWATLRAGNLYFAMALHLSWNLVQG 227 +V+I+S++FS H+ NP ++ LNI LI ++FS+ L+ GNL+ + H+SWN QG Sbjct: 178 VSVLISSIIFSLMHILNPNIVFLGLLNIFLIGVLFSYMYLKTGNLWMPIGYHISWNYFQG 237 Query: 228 YGFGVSVSGNIQQGLYSVMLEGPDWITGGSFGLEA 262 Y FG +VSGN +G+Y+ ++++GG FGLE Sbjct: 238 YIFGFNVSGNAIRGIYNA-FPKNNFLSGGDFGLEG 271 >C2KS73.1 C2KS73_9ACTO Possible metal-dependent membrane protease Length = 323 Score = 102 bits (254), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 72/191 (37%), Positives = 106/191 (55%), Gaps = 16/191 (8%) Query: 79 QPLSTIGLTRPDVKRFAQGLLSGALLMAIIVMVLWALG----NAVFQNEGWTPRFSQLDL 134 +P++ +G T +K A G+L G++L+++ +++LWA G N+ N G L Sbjct: 85 RPVTELGATG-CIKETALGILVGSVLVSLPMLILWARGFWRFNSFAINSG------ILKG 137 Query: 135 PGLVLTACIAGICEEALFRGYIQHLLTSRLGTVWAVVITSVLFSAAHMANPGYNWISALN 194 G+ L AC+ EE L RG LL + G A+V+TS++F A H++NPG W+ AL Sbjct: 138 IGIGLIACV---FEELLMRGVFLRLLEQKWGAPGALVVTSLVFGAMHLSNPGVTWLGALT 194 Query: 195 I-VLIALIFSWATLRAGNLYFAMALHLSWNLVQGYGFGVSVSGNIQQ-GLYSVMLEGPDW 252 I V + A L L+F + LH WN +Q +GV+VSG +Q GL L GP W Sbjct: 195 IGVEAGFLLGTAYLWKRRLWFPIGLHFGWNAMQAAFWGVNVSGTGKQSGLLDGTLHGPTW 254 Query: 253 ITGGSFGLEAS 263 +TGGS G+E S Sbjct: 255 LTGGSVGIEGS 265 >B1DM63.1 B1DM63_9BACL Abortive infection protein Length = 290 Score = 95.5 bits (236), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Query: 88 RPDVKRFAQGLLSGALLMAIIVMVLWALGNAVFQNEGWTPRFSQLDLPGLVLTACIAGIC 147 + V R QG +G LLM + +++WA G ++ W G++L +A + Sbjct: 88 KHGVDRGLQGFFAGILLMTLSAILIWAAGGVSWEASKWDQTLILSLFEGIILYIFVA-LS 146 Query: 148 EEALFRGYIQHLLTSRLGTVWAVVITSVLFSAAHMANPGY--NWISALNIVLIALIFSWA 205 EE RGYIQ L+ GT A++++S++F+ H NP +NI L ++FS A Sbjct: 147 EELFTRGYIQGLIKYHYGTPAAIIVSSIIFALMHSMNPNMYETPFPFINICLAGILFSVA 206 Query: 206 TLRAGNLYFAMALHLSWNLVQGYGFGVSVSGNIQ-QGLYSVMLEGPDWITGGSFGLEAS 263 G L++ + LH+SWN QGY +G VSG + V GP ++GG FG E S Sbjct: 207 RELTGGLWWPIGLHMSWNFFQGYVYGFQVSGTEPVPAVLQVTDNGPIQLSGGEFGAEGS 265 >B3QY90.1 B3QY90_CHLT3 Abortive infection protein Length = 326 Score = 95.1 bits (235), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 64/169 (37%), Positives = 89/169 (52%), Gaps = 4/169 (2%) Query: 96 QGLLSGALLMAIIVMVLWALGNAVFQNEGWTPRFSQLDLPGLVLTACIAGICEEALFRGY 155 QG+ G LLM+ + +LW L V+Q G F L T AG EE LFR Sbjct: 116 QGIGVGTLLMSSSIFILWLLD--VYQVHG-LHSFDALVASSHFRTTVFAGYIEELLFRAI 172 Query: 156 IQHLLTSRLGTVWAVVITSVLFSAAHMANPGYNWISALNIVLIA-LIFSWATLRAGNLYF 214 + + +LGT A+ + ++LF H ANPG +W S+L I L A L+ A + L+ Sbjct: 173 VFRISEEKLGTWIALALQAILFGFLHAANPGASWFSSLAISLEAGLLLGAAYVLTRRLWL 232 Query: 215 AMALHLSWNLVQGYGFGVSVSGNIQQGLYSVMLEGPDWITGGSFGLEAS 263 A+ +H +WN QG FG++VSG GL L G W++GG+FG E S Sbjct: 233 AIGIHAAWNYTQGAIFGIAVSGYNVPGLLDAELTGNKWLSGGAFGAETS 281 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.327 0.139 0.435 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,558,890,702 Number of extensions: 56914048 Number of successful extensions: 187069 Number of sequences better than 1.0e-05: 349 Number of HSP's gapped: 187144 Number of HSP's successfully gapped: 349 Length of query: 297 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 162 Effective length of database: 1,788,859,178 Effective search space: 289795186836 Effective search space used: 289795186836 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 131 (55.1 bits)