BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0014.p (516 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver 379 e-103 B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, A... 352 6e-95 Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator 283 2e-74 Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator 233 3e-59 B9MLE2.1 B9MLE2_ANATD Two component transcriptional regulator, A... 226 6e-57 >B3KDQ8.1 B3KDQ8_9BACI Response regulator receiver Length = 518 Score = 379 bits (972), Expect = e-103, Method: Compositional matrix adjust. Identities = 215/522 (41%), Positives = 307/522 (58%), Gaps = 19/522 (3%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VLIVDDE +REGL +++ W LGY VVDTAAN EA K+ + PDLM+IDIRMPG DG Sbjct: 4 VLIVDDEPKLREGLKSIVPWTELGYQVVDTAANGNEALEKHGKYDPDLMLIDIRMPGMDG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L+LI+ +R D E+H++ILSGYADF YAKRA+S +D YLLKPVDEDEL YL + + Sbjct: 64 LQLIEAIRNLDAEIHLLILSGYADFDYAKRAISHRVDGYLLKPVDEDELSKYLLQIKEAI 123 Query: 121 AARAVYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLIRLLL 180 + + A SRE +Q+ AAL A SGLLW+ YQV+L Sbjct: 124 EQEQERKALNRAASEMSREQFIQTWFNPESKPDSAALRHMAERSGLLWNHYQVLLFHHNG 183 Query: 181 QDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVLLQPSYQKELVRQLMVRNIWEAV 240 D + +K +L +FEE G VFSL LG+L+ R+ +++ + EA Sbjct: 184 SDESGEETDDRLKNQLIEAFEENGRGAVFSLHGQLGILMPTPVLTAGGRKELLQLVEEAA 243 Query: 241 TAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKLKTG------ 294 + G + G V LE+V S A R++E FFY M+ P+S + G Sbjct: 244 SRAGTAITASLGRQVHRLEDVADSYRCAKERIRERFFYAPGEMLFPESERFAGGNTDEER 303 Query: 295 LPVKPEEVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYVRLV 354 P PE+ + E+LY+A+D+G++ + L+ A + M+ Y+E +K +V L+ Sbjct: 304 QPYDPEQ-------LMEQLYYAVDVGNVEVQQKLLYTAASAMVKEEYTEERMKRAFVELL 356 Query: 355 THLMNKLSLQYRELELLHSRMDEQVEQIYKHTSLPKLQSHINVLLEQ---YAGGIKRDDM 411 T + NKL + EL+ +++ I++ + L H + LE+ AG RD Sbjct: 357 TGVHNKLMQHHTELQSRTKEYSDRIAAIFRQRTAYDLCRHSSQFLEELIWQAGNGGRDQE 416 Query: 412 EVLIKRMLDLIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAK 471 +KR++DLI R+Y EN+KLETLA +F Y+SAYLGK+FK++TG FN+YLD +RI KAK Sbjct: 417 ---MKRIMDLIQRNYNENIKLETLASIFNYNSAYLGKMFKNTTGEYFNTYLDKVRIDKAK 473 Query: 472 ELLDQGYKIHQAASEVGFSDVDYFREKFKKIEGLSPSDYRRK 513 + L QG K++Q A +VG+++VDYF KFKK G SPS++R++ Sbjct: 474 DFLKQGMKVYQVAEKVGYTNVDYFHSKFKKYVGTSPSNFRKE 515 >B1D7X3.1 B1D7X3_9BACL Two component transcriptional regulator, AraC family Length = 507 Score = 352 bits (902), Expect = 6e-95, Method: Compositional matrix adjust. Identities = 200/515 (38%), Positives = 307/515 (59%), Gaps = 11/515 (2%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VL+VDDE IREGL TLL+WESLGY VVDTAAN +A K E H DL+I+DIRMP +G Sbjct: 4 VLLVDDEPMIREGLRTLLEWESLGYEVVDTAANGKDALQKCEQHDLDLIIVDIRMPEMNG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 LELIK++RE+ +H++ILSGYADF YAK+A+ ID YLLKPVDEDEL YL +L EL Sbjct: 64 LELIKKIRENGGTMHVLILSGYADFEYAKQAIVQRIDGYLLKPVDEDELMEYLHSLRKEL 123 Query: 121 AARAVYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLIRLLL 180 R+K + + E ++ LL++ + + + + W ++++LI+ Sbjct: 124 DLEYETRQKRLDERQGNAEDDLKRLLVEGSTGSSLSPLSASPD----WKEFELLLIKTHE 179 Query: 181 QDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVLLQPSYQKELVRQLMVRNIWEAV 240 ++ + +K RL+ ++ G+ +++ YL VLL E R+ M I +A Sbjct: 180 RNEEETAGHAQIKRRLSERLDQSGGGLAIAMEPYLLVLLNKGLDNERFRRDMHAMIADAC 239 Query: 241 TAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKLKTGLPVKPE 300 + + +G ++ A+ + AL RMK FF + D +P E Sbjct: 240 EGLASDFTVVSGGNASGNADIQAAYQKALERMKNRFFLKGGQITAEDP-----QMPAGSE 294 Query: 301 EVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYVRLVTHLMNK 360 + +P L E+LY A++I + + I+E+ M A G+ E +K+ +V LV+ +++K Sbjct: 295 DAKPDLTGTAEKLYLALEIVNREAIRQQIEESAEAMKAIGFGEAEMKAAFVELVSAVLDK 354 Query: 361 LSLQYRELELLHSRMDEQVEQIYKHTSLPKLQSHINVLLEQYAGGIKRDDMEVLIKRMLD 420 L+ + EL++ R +++ ++++ + L +++Q A + + IKRM+D Sbjct: 355 LASKRPELQVRDYR--QRIPELFREYRISSLTRLATAIIDQIADSLDNSSADKQIKRMID 412 Query: 421 LIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKELLDQGYKI 480 LIHR+Y ENLK+ETLA++F Y+SAYLGKLFK TG +FN+YLD +R+ +AK LL+QG K+ Sbjct: 413 LIHRNYKENLKMETLAELFNYNSAYLGKLFKQVTGENFNTYLDKVRMEQAKILLEQGLKV 472 Query: 481 HQAASEVGFSDVDYFREKFKKIEGLSPSDYRRKNS 515 +Q A VG+++VDYF KF+K G SPS YR+K+S Sbjct: 473 YQVAEMVGYANVDYFHSKFRKYVGSSPSVYRKKDS 507 >Q9KBL6.1 Q9KBL6_BACHD Two-component response regulator Length = 506 Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 175/514 (34%), Positives = 282/514 (54%), Gaps = 19/514 (3%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 V+IVDDE +REGL L+ WE G+ V+DTA N E KY SPDLMI+DIRMP DG Sbjct: 4 VMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L LI+ +R +D +H IILSG++DF+YAK+A+ D+YLLKP+DEDEL L + + Sbjct: 64 LSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVYGRI 123 Query: 121 AARAVYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLIRLLL 180 + V+ EM++ LL + P + + E YQV L+ Sbjct: 124 TRHHQVHELVERVQEKQVEMVLTELL-EGTPLSEIPI---GKEHNFFATDYQVALV---- 175 Query: 181 QDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVLLQPSYQKELVRQLMVRNIWEAV 240 +N K +L EEQE G V Y+ ++ + + ++ + + + Sbjct: 176 ----ENRQDRLTK-QLKRLIEEQEEGYVIPFPEYIVIVCKNRFLQKRGKDHRYHLFAKWL 230 Query: 241 TAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKLKTGLPVKPE 300 + L AG V +L ++ S +SA ++ FF ++ + D L ++ KPE Sbjct: 231 EEEELHA--CAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRS----KPE 284 Query: 301 EVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYVRLVTHLMNK 360 E L +RLY+++DIG++ ++I+E ++I E +K +L ++++++ Sbjct: 285 APEFSLESYADRLYYSIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQLYSNILHQ 344 Query: 361 LSLQYRELELLHSRMDEQVEQIYKHTSLPKLQSHINVLLEQYAGGIKRDDMEVLIKRMLD 420 L + +E + + IY+ LP + + + L+ + ++L+++M+ Sbjct: 345 LVRSHPNMEGVLEPLVMNAGDIYQFEHLPGIMAFLTKQLKYVIDCMDNGQPDLLLRKMIA 404 Query: 421 LIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKAKELLDQGYKI 480 LIH+ Y +NL+LETLA VF Y+ AYLGKLFK+ TG FN+YLD +RI K LL +GYK+ Sbjct: 405 LIHKDYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLLQKGYKV 464 Query: 481 HQAASEVGFSDVDYFREKFKKIEGLSPSDYRRKN 514 ++ A ++G+++VDYF KFKK G+SPS +R+++ Sbjct: 465 YEVAEKIGYANVDYFHRKFKKYVGVSPSTFRKRH 498 >Q5WIY3.1 Q5WIY3_BACSK Two-component response regulator Length = 493 Score = 233 bits (594), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 174/530 (32%), Positives = 267/530 (50%), Gaps = 56/530 (10%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 VLI DDE IREG+ L+ WE G+ V A N +A KY+ PDL+I DIRMP DG Sbjct: 4 VLIADDEWMIREGVKNLIPWEHYGFEVASLACNGKDALEKYKHDKPDLVIADIRMPQMDG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L L+KE+R ++ + ++LSG+ADF YA+ A+ G+D YLLKP++EDEL +L + +L Sbjct: 64 LSLLKEIRTENEAVPFLLLSGHADFHYAQEAIGHGVDGYLLKPLEEDELIEHLQIVFHKL 123 Query: 121 AARA-VYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLI--- 176 R + + +V+I +L+ L G P +++ + GL YQ+ L+ Sbjct: 124 EQRKQAHVLRQQSVRIEQERLLLNLL---AGKPLPTSVDFSRL--GLAASRYQIFLVHAG 178 Query: 177 -RLLLQDNADNGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVL---LQPSYQKELVRQLM 232 R L+ A+ P TAV F+ G+L LQ K ++Q Sbjct: 179 ERDALEHLAEQIPHTAVP---------------FAKGGDAGLLICHLQEGLTKSELQQWA 223 Query: 233 VRNIWEAVTAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKLK 292 + A G G V L + S +A + F+ D+ +I L+ Sbjct: 224 SHLL--APMRHG-----ALGKCVRKLSAIQVSYTAAKKLLSLAFYADKGSVISELPTVLQ 276 Query: 293 TG-LPVKPEEVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYV 351 G L KP L+ ER+Y A+ IG + + A + A E ++K++ Sbjct: 277 DGQLAKKP------LSFYEERIYLALHIGEKEPAKQAVSDFLADVAARRMKEASLKAKAS 330 Query: 352 RLVTHLMNKLSLQYRELELLHSRMDEQVEQIYKHTS-------LPKLQSHINVLLEQYAG 404 L +++ +L H E ++ Y+ T+ +L+ + L ++ A Sbjct: 331 ELALNVIQRLIAS-------HVLAKEWAQKGYRFTAQLQEAEDFLQLRHVLRCLCDELAA 383 Query: 405 GIKRDDMEVLIKRMLDLIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDN 464 + +K+M+D+I Y ENL+LET++ V Y+SAYLGK FK TG FN+YLD Sbjct: 384 NTNVRSNDTAVKKMIDMIDSRYDENLRLETISAVLNYNSAYLGKRFKQETGDYFNTYLDK 443 Query: 465 IRIGKAKELLDQGYKIHQAASEVGFSDVDYFREKFKKIEGLSPSDYRRKN 514 +RI K+KELL G K+++AA +VG+ +VDYF KFKK G+SPS +R+K+ Sbjct: 444 VRIHKSKELLRAGCKVYEAAEKVGYPNVDYFHRKFKKYTGMSPSAFRKKD 493 >B9MLE2.1 B9MLE2_ANATD Two component transcriptional regulator, AraC family Length = 519 Score = 226 bits (575), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 155/521 (29%), Positives = 265/521 (50%), Gaps = 21/521 (4%) Query: 1 VLIVDDELAIREGLATLLDWESLGYVVVDTAANAIEAKHKYELHSPDLMIIDIRMPGRDG 60 V+++DDE I EGL +LDW +LG+ +V A + ++ K +PD+ +IDIR+PG DG Sbjct: 4 VVLIDDEPIIIEGLKKILDWHALGFEIVAVAYDGVDGFSKLLELNPDVALIDIRIPGIDG 63 Query: 61 LELIKELREDDPELHIIILSGYADFSYAKRAMSLGIDNYLLKPVDEDELHLYLTNLSAEL 120 L LI+ LRE + IIILSGY++F YA++A+ LG+++YLLKP+D+ L L + +L Sbjct: 64 LLLIQRLREKNISTKIIILSGYSEFEYARKAVELGVESYLLKPIDKQLLEEKLMAIREKL 123 Query: 121 AARAVYRKKDAAVKIWSREMLVQSLLLDNGPQAPAALEGPAMESGLLWDSYQVVLIRLLL 180 + +A K +RE +V+ L+L E L W YQV +I+LL Sbjct: 124 EEEFKINRAFSAAKKLTREKVVEKLVLGTLKDTEIEYMNKFFELQLPWKKYQVAIIQLLN 183 Query: 181 QDNAD---NGPSTAVKTRLAASFEEQEWGIVFSLDSYLGVLLQPSYQKELVRQLMVRNIW 237 ++ N +K ++ + G +++ + +L + + R + + Sbjct: 184 ENRNSCEINQTVLQLKEKVDLFLNKNSCGFSTIINNNICILFKDFWYPFNSRSINILKDM 243 Query: 238 EAVTAQGLECIITAGDMVDSLEEVPASKESALARMKEHFFYDEPGMIGPDSLKL---KTG 294 G + II+ G V+ + S E A +K+ F G+I KT Sbjct: 244 LMKYTDG-QIIISIGSEVEDYRNIKKSFEEANELLKKRFLLGYKGLIFIKEAIFRYDKTE 302 Query: 295 LPVKPEEVEPGLAPVTERLYFAMDIGSLNLLPSLIQEAGALMIAAGYSEMAVKSRYVRLV 354 +E LA A++ + + ++++ +I SE KS + Sbjct: 303 KEFDDKENAYALAV-------AIEFENFERINNILENKADNLIKKNASEDEAKSSFYNFF 355 Query: 355 THLMNKLSLQYRELELLHSRMDEQV-EQIYKHTSLPKLQSHINVLLEQYAGGIKR---DD 410 ++ KLS +++ + +++ + ++ +L +L+ I A IK+ D+ Sbjct: 356 VDVLYKLSQNQEYKQIVEKYLTQEIFKNLFTQKTLTELKGLIKYYFTLIAEQIKKLHSDN 415 Query: 411 MEVLIKRMLDLIHRHYPENLKLETLADVFTYSSAYLGKLFKSSTGLSFNSYLDNIRIGKA 470 +V ++ + I R+Y +LKLETLA++F Y+S+Y KLFK + G +F+S+++ +RI KA Sbjct: 416 FKVQVE---EFIKRNYFIDLKLETLAEIFGYNSSYFSKLFKKTFGENFSSFIEKVRIEKA 472 Query: 471 KELLDQGYKIHQAASEVGFSDVDYFREKFKKIEGLSPSDYR 511 KELL+ G K+ + A +VG+ D+DYF KFKK G SP Y+ Sbjct: 473 KELLENGKKVSEVAKKVGYEDMDYFCLKFKKYVGCSPKSYK 513 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,003,664,913 Number of extensions: 123902997 Number of successful extensions: 454300 Number of sequences better than 1.0e-05: 16117 Number of HSP's gapped: 468677 Number of HSP's successfully gapped: 16772 Length of query: 516 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 376 Effective length of database: 1,741,754,103 Effective search space: 654899542728 Effective search space used: 654899542728 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)