BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0073.0005.p (432 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D595.1 B1D595_9BACL Two component transcriptional regulator, A... 582 e-164 Q5WL29.1 Q5WL29_BACSK Two-component response regulator 229 4e-58 B3KAH7.1 B3KAH7_9BACI Response regulator receiver 224 1e-56 Q9KDT8.1 Q9KDT8_BACHD BH1123 protein 166 6e-39 B1DIP6.1 B1DIP6_9BACL Two component transcriptional regulator, A... 163 3e-38 >B1D595.1 B1D595_9BACL Two component transcriptional regulator, AraC family Length = 421 Score = 582 bits (1501), Expect = e-164, Method: Compositional matrix adjust. Identities = 299/436 (68%), Positives = 340/436 (77%), Gaps = 19/436 (4%) Query: 1 MWKVVIIDDDFQVVRGLRKAIPWEELDAEFAGEAIDGESGLKLIGEVNPDIVLTDIYMPV 60 MWK+VIIDDDFQVVRGLRKAIPWEELDAEFAG+AIDGE+GLKLI EVNPDIVLTDIYMP Sbjct: 1 MWKIVIIDDDFQVVRGLRKAIPWEELDAEFAGDAIDGEAGLKLIEEVNPDIVLTDIYMPE 60 Query: 61 MNGIQMIEQLKAGSFAGRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIRKVLSETI 120 MNGIQMIE LK SF GRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIR+VL+ETI Sbjct: 61 MNGIQMIEALKHQSFTGRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIRQVLAETI 120 Query: 121 EKLEETYLHRLELGGGQSSD----RQEAPSLAEWLVAVLNGWSQNPGLPAPLQQLDKQRY 176 KLEETYL RLE S RQE EW ++LNG +Q LPA L + +++ Sbjct: 121 HKLEETYLQRLEQTEEPSYPAKNWRQE-----EWTASILNGLTQPEELPAALSEWRDKQF 175 Query: 177 TVMVMEVLWTERIRSVSLADWNLFQFAVSNIVTEVYGREWPEAFFVWLFGNHAALLLPSA 236 TVMV+EV WTER R++S+ADWNLF+FAV+NI EV EW A FVWLFGN+AA+LL S Sbjct: 176 TVMVLEVAWTERTRNISIADWNLFRFAVANISEEVLLGEWRTASFVWLFGNYAAVLLRSE 235 Query: 237 AQGPEGQIIQAADALGALIVSSIKTFLGLEVRFGIGNVKDGWDEIKASGDEAMQRLFAKL 296 AA+ LG LI++ +K+++GL+ RFG+G KD W EIKAS DEA+Q L Sbjct: 236 PGTDALHTASAAERLGGLIINYLKSYIGLDARFGLGRTKDSWQEIKASCDEALQGLLE-- 293 Query: 297 PLNLNHEKVWSGGAETQIDGLRKAQGPTIHDKHRKAVQFMIEYIHTHYAEDITLEHLASQ 356 + + E+ T++ TIH+KHRKAVQ+MIEY+HTHYAEDITLE LASQ Sbjct: 294 --DPDREQQAEEPQATELS------FNTIHEKHRKAVQYMIEYVHTHYAEDITLEQLASQ 345 Query: 357 LYISKNYLNQLFKKVTGETFTNYVIRVRIEKAKTLLQGGSHLIYEVSEMVGYQNVPYFST 416 LYISKNYLNQLFKKVTGETFTNYVIRVRIEKAK LL G HLIYEVSEMVGYQNVPYF+T Sbjct: 346 LYISKNYLNQLFKKVTGETFTNYVIRVRIEKAKVLLLEGKHLIYEVSEMVGYQNVPYFTT 405 Query: 417 LFKKYCGVSPSELMKR 432 LFKKYCGV+PSELMK+ Sbjct: 406 LFKKYCGVTPSELMKQ 421 >Q5WL29.1 Q5WL29_BACSK Two-component response regulator Length = 368 Score = 229 bits (584), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 145/433 (33%), Positives = 223/433 (51%), Gaps = 68/433 (15%) Query: 1 MWKVVIIDDDFQVVRGLRKAIPWEELDAEFAGEAIDGESGLKLIGEVNPDIVLTDIYMPV 60 MWK VIIDDD QV+ GL+ IPWE + F GEA DGE G+KLI P+IV+TDIYMPV Sbjct: 1 MWKTVIIDDDEQVIEGLKGIIPWERFNMTFVGEAYDGEEGIKLIQTNQPNIVVTDIYMPV 60 Query: 61 MNGIQMIEQLKAGSFAGRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIRKVLSETI 120 + G+ M++ ++ FAG+ VILSG++DFEYAR ALRL VDDYL+KP + I V + + Sbjct: 61 LEGLAMVKTVRDEGFAGKVVILSGFDDFEYARQALRLRVDDYLSKPASKMTIFTVFEKIV 120 Query: 121 EKLEETYLHRLELGGGQSSDRQEAPSLAEWLVAVLNGWSQNPGLPAPLQQLDKQRYTVMV 180 +L ++ + ++ L L AV P L P + + ++ + Sbjct: 121 NRL-----------TAEAEEEIKSKQLEIRLNAVA------PLLDRPFEITGE---SLPL 160 Query: 181 MEVLWTERIRSVSLADWNLFQFAVSNIVTEVY-GREWPEAFFVWLFGNHAALLLPSAAQG 239 E L T +V DW+ Q A +V+ ++ +E + N L+ A + Sbjct: 161 YETLAT----AVRDNDWSKAQQAARAVVSYLHDAKELERPSLLHFHANSLQALIRDAVRN 216 Query: 240 PEGQIIQAADALGALIVSSIKTFLGLEVRFGIGNVKDGWDEIKASGDEAMQRLFAKLPLN 299 GQ + A + ++ + D+ L Sbjct: 217 RTGQHVCA-------------------------------NRVEVAPDQL---------LT 236 Query: 300 LNHEKVWSGGAETQIDGLRKAQGPTIHDKHRKAVQFMIEYIHTHYAEDITLEHLASQLYI 359 + + W E+Q+D A + +HR+AVQ I+Y+H HY ED+ L+ +A ++ + Sbjct: 237 IKDFEAW---IESQVDQACIASISEGNARHRRAVQMTIDYVHAHYNEDLVLKDIAEEVGL 293 Query: 360 SKNYLNQLFKKVTGETFTNYVIRVRIEKAKTLLQGGSHLIYEVSEMVGYQNVPYFSTLFK 419 S+ YL +F+K GE+F +Y+ RVR+EKAK LL G IYE+++ VGY +V YF+ FK Sbjct: 294 SRKYLGIVFQKAVGESFKSYLTRVRMEKAKQLLLEGELYIYEIADQVGYSHVHYFTRQFK 353 Query: 420 KYCGVSPSELMKR 432 ++ SP+E + + Sbjct: 354 RFFHASPTEFINQ 366 >B3KAH7.1 B3KAH7_9BACI Response regulator receiver Length = 540 Score = 224 bits (572), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 118/296 (39%), Positives = 187/296 (63%), Gaps = 6/296 (2%) Query: 1 MWKVVIIDDDFQVVRGLRKAIPWEELDAEFAGEAIDGESGLKLIGEVNPDIVLTDIYMPV 60 MWK+ I+DDD V++G+RKAIPW+EL+AE+AGEA++GE GL++I NPDIV+TD+YMPV Sbjct: 1 MWKIGIVDDDRAVLQGIRKAIPWDELNAEWAGEALNGEEGLEMIESANPDIVITDLYMPV 60 Query: 61 MNGIQMIEQLKAGS-FAGRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIRKVLSET 119 MNG+ MIEQL+ + ++G+ +ILSGY+DFEYAR ALRL V DYL+KP+++ ++ VL+E Sbjct: 61 MNGLDMIEQLRKNTGYSGKVIILSGYSDFEYARQALRLNVSDYLSKPISLPTLKSVLNEA 120 Query: 120 IEKLEETYLHRLELGGGQSSDRQEAPSL-AEWLVAVLNGWSQNPGL----PAPLQQLDKQ 174 I LEE R++ + P + EW+ + G + GL P P + Sbjct: 121 ISDLEEQEEQRMKQDELLQKLQLYEPFVEKEWVKSAAAGALLHSGLQTEIPEPYRYWSDF 180 Query: 175 RYTVMVMEVLWTERIRSVSLADWNLFQFAVSNIVTEVYGREWPEAFFVWLFGNHAALLLP 234 +TV+ +E+++ +R ++SL DW+L +FA+SN+V E+ +P L N + +++ Sbjct: 181 DHTVVGIELIYDQRAANLSLPDWSLLRFAISNMVCEITQAAFPRFDHTDLHTNRSVVIIH 240 Query: 235 SAAQGPEGQIIQAADALGALIVSSIKTFLGLEVRFGIGNVKDGWDEIKASGDEAMQ 290 ++ Q + LG ++ ++ +L L++R GIG+ K EI S +EA + Sbjct: 241 HDRTESAERVRQQLEQLGVRLIDCVQNYLKLKLRIGIGDRKSSIREIGISTEEAFR 296 Score = 149 bits (375), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 66/104 (63%), Positives = 88/104 (84%) Query: 328 KHRKAVQFMIEYIHTHYAEDITLEHLASQLYISKNYLNQLFKKVTGETFTNYVIRVRIEK 387 KHR+AV FMIEYIH HYAED+TL LA ++YIS+NYL+ +FK +TGETF NY+ RVR+EK Sbjct: 437 KHRQAVDFMIEYIHEHYAEDLTLGGLADKVYISRNYLSMIFKNMTGETFNNYLTRVRVEK 496 Query: 388 AKTLLQGGSHLIYEVSEMVGYQNVPYFSTLFKKYCGVSPSELMK 431 A+ LL + L+Y+V+E VGY+NVPYFST+FKK+ G++P+EL+K Sbjct: 497 ARELLMEKNALVYQVAEQVGYKNVPYFSTVFKKFTGMNPTELVK 540 >Q9KDT8.1 Q9KDT8_BACHD BH1123 protein Length = 526 Score = 166 bits (419), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 105/298 (35%), Positives = 156/298 (52%), Gaps = 16/298 (5%) Query: 1 MWKVVIIDDDFQVVRGLRKAIPWEELDAEFAGEAIDGESGLKLIGEVNPDIVLTDIYMPV 60 MWKVVIIDD+ VVRGL+K I W+ L E GEA +G GL ++ E +P IVLTDIYMP+ Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MNGIQMIEQLKAGSFAGRFVILSGYNDFEYARTALRLGVDDYLTKPVTVDQIRKVLSETI 120 M G+ MI+ L+ F G VILSGY++FE+AR A++L + DYL+KP +VD I VL I Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 EKLEET-----YLHRLELGGGQSSDRQEAPSLAEWLVAVLNGWSQNPGLP----APLQQL 171 KLEE YL L R E EW+ ++L G +N +P A + + Sbjct: 121 NKLEEKQRQQGYLQEL----TNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKW 176 Query: 172 DKQRYTVMVMEVLWTERIRSVSLADWNLFQFAVSNIVTEVYGREWPEAF-FVWLFGNHAA 230 Q++ + + + + ADW LF+++V ++ EV +P F ++ + +A Sbjct: 177 KDQQHIACSLTYDGPQN-KELKPADWYLFRYSVHKMIREVLNG-YPIDFRYLEMDAYRSA 234 Query: 231 LLLPSAAQGPEGQIIQAADALGALIVSSIKTFLGLEVRFGIGNVKDGWDEIKASGDEA 288 L L E + + + I + ++ G VK+ W ++ S EA Sbjct: 235 LCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFHEA 292 Score = 128 bits (321), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 58/105 (55%), Positives = 83/105 (79%) Query: 328 KHRKAVQFMIEYIHTHYAEDITLEHLASQLYISKNYLNQLFKKVTGETFTNYVIRVRIEK 387 KH++ ++ ++ YI H AE+ITL+ +A +LYIS+NYL Q+FKKV GE+F NYV R+R+EK Sbjct: 421 KHKQLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEK 480 Query: 388 AKTLLQGGSHLIYEVSEMVGYQNVPYFSTLFKKYCGVSPSELMKR 432 AK ++Q G+ LIYEVSE VGY N YF+T+FKKY G +P +L+++ Sbjct: 481 AKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRDLIQK 525 >B1DIP6.1 B1DIP6_9BACL Two component transcriptional regulator, AraC family Length = 444 Score = 163 bits (413), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 130/453 (28%), Positives = 227/453 (50%), Gaps = 31/453 (6%) Query: 1 MWKVVIIDDDFQVVRGLRKAIPWEELDAEFAGEAIDGESGLKLIGEVNPDIVLTDIYMPV 60 M+ ++++DD+ + +GL + +D A +G L ++ + D+++TDI M Sbjct: 1 MYNILVVDDEPLICKGLSSVLASSGIDISAIHMAHNGYEALDVLRTDDIDLLITDIQMGT 60 Query: 61 MNGIQMIEQLKAGSFAGRFVILSGYNDFEYARTALRLGVDDYLTKPVT----VDQIRKVL 116 MNGI++++Q K + +I+S + F YA+ A+RLG DYL KP+ +D +R VL Sbjct: 61 MNGIELMQQAKLIKPWVQTIIISAHETFHYAQMAIRLGAKDYLIKPLNNEQFLDSVRNVL 120 Query: 117 SETIEKLEETYLHRLELGGGQSSDRQE-APSLAEWLVAVLNGWSQNPGLPAP-----LQQ 170 + + K E +L G + E P +WL + +G P L L++ Sbjct: 121 LK-LHKPEPAEQEKLIAGMQEHFHMDELNPQSVDWLNQLASG---QPSLKVQDIIRILKE 176 Query: 171 -----LDKQRYTVMVMEVLWTERIRSVSLADWNLFQFAVSNIVTEVYGREWPEAFFVWLF 225 L+ ++++ + + T+R R ++ AD L ++A NIV E++ W F Sbjct: 177 KHGIRLEGPYFSMIRIRLNLTDRNRELTKADEGLLRYAALNIVNELFDEHWNNTAFYASE 236 Query: 226 GNHAALLLPSAAQGPEGQ---IIQAADALGALIVSSIKTFLGLEVRFGIGNVKDGWDEIK 282 +L + Q E I+ D +G + +I+ +LG+ GI + G + I Sbjct: 237 REITIILQWNETQYGETASSGIMNELDMIGRSLQFNIQKYLGIASVIGISQILKGIEFID 296 Query: 283 ASGDEAMQRLFAKLPLNLNHEKVWSGGAETQIDGLRKAQGPTIHDKHRKA---VQFMIEY 339 D+ ++ L + +H + G + + +Q PT + + V+ +EY Sbjct: 297 VLQDQVIKALSCN-DRHKDHYVFYYGD----FNWNQYSQRPTEEEFTAQTSLIVEKAMEY 351 Query: 340 IHTHYAED-ITLEHLASQLYISKNYLNQLFKKVTGETFTNYVIRVRIEKAKTLLQGGSHL 398 I+ +YA+ +TL +A ++S NYL+ LFKK TG YV+++R+E++K LL Sbjct: 352 INQNYAQKGLTLHEVAQNNHVSPNYLSYLFKKETGYNLWEYVVKLRMEESKRLLLQTDMR 411 Query: 399 IYEVSEMVGYQNVPYFSTLFKKYCGVSPSELMK 431 YE+SE VGY++ +FS +FKKY G+SPSEL K Sbjct: 412 RYEISEKVGYESPEHFSKIFKKYYGMSPSELKK 444 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,587,451,128 Number of extensions: 107734468 Number of successful extensions: 362772 Number of sequences better than 1.0e-05: 9486 Number of HSP's gapped: 377340 Number of HSP's successfully gapped: 10233 Length of query: 432 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 293 Effective length of database: 1,751,175,118 Effective search space: 513094309574 Effective search space used: 513094309574 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)