BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0063.0006.p (488 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B2BCX0.1 B2BCX0_PAEPO Inosine-5'-monophosphate dehydrogenase EC=... 867 0.0 B3KK85.1 B3KK85_9BACI Inosine-5'-monophosphate dehydrogenase EC=... 855 0.0 B1DKC5.1 B1DKC5_9BACL Inosine-5'-monophosphate dehydrogenase EC=... 808 0.0 C0ZH50.1 C0ZH50_BREBN Inosine-5'-monophosphate dehydrogenase EC=... 758 0.0 C5D335.1 C5D335_9BACI Inosine-5'-monophosphate dehydrogenase EC=... 738 0.0 >B2BCX0.1 B2BCX0_PAEPO Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 485 Score = 867 bits (2239), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/485 (87%), Positives = 446/485 (91%) Query: 4 VWEDKFGKEGLTFDDVLLVPRKSEVLPKEVDLSTVLSKNVKLNIPLMSAGMDTVTEXXXX 63 +WEDKFGKEGLTFDDVLLVPRKS VLPKEV ++T LS NVKLNIPLMSAGMDTVTE Sbjct: 1 MWEDKFGKEGLTFDDVLLVPRKSVVLPKEVSVATRLSDNVKLNIPLMSAGMDTVTEAVLA 60 Query: 64 XXXXXXXXXXXXHKNMSVEQQAEEVDRVKRSESGVITNPFSLTPDHWVSDAEVLMGKYRI 123 HKNMS+EQQA EVDRVKRSESGVITNPFSLTPDH VSDAE +MGKYRI Sbjct: 61 IAMAREGGIGIIHKNMSIEQQAVEVDRVKRSESGVITNPFSLTPDHLVSDAEAVMGKYRI 120 Query: 124 SGVPIVDEGNKLVGILTNRDLRFIHDFNIQIKEVMTHENLVTAAVGTTLQEAEVILQRHK 183 SGVP+V+E NKLVGI+TNRDLRFIHDFN++I EVMT E LVTA VGTTLQEAEVILQ+HK Sbjct: 121 SGVPVVNEENKLVGIITNRDLRFIHDFNLKISEVMTKEELVTAPVGTTLQEAEVILQKHK 180 Query: 184 IEKLPLVDENNILKGLITIKDIEKAIQFPNGAKDAQGRLLVGAAIGISKDTFERTEALIK 243 IEKLPLVD+ N LKGLITIKDIEKAIQFPN AKDAQGRLLVGAA+GISKDTF+RTEAL+K Sbjct: 181 IEKLPLVDDENYLKGLITIKDIEKAIQFPNAAKDAQGRLLVGAAVGISKDTFDRTEALVK 240 Query: 244 AGVDLITVDSAHGHHINIIDAVRKLRELYPDLTIVAGNVATGEATRELIEAGASVVKVGI 303 AGVD+I VDSAHGHHINII+AVRKLRE YPDLTIVAGNVATG+ TRELIEAGASVVKVGI Sbjct: 241 AGVDMIVVDSAHGHHINIIEAVRKLREAYPDLTIVAGNVATGDGTRELIEAGASVVKVGI 300 Query: 304 GPGSICTTRVIAGIGVPQITAIYDCATVAREYGIPIIADGGIKYSGEITKAIAAGASAVM 363 GPGSICTTRVIAGIGVPQ+TAIYDCATVAREY IPIIADGGIKYSGEITKAIAAGASAVM Sbjct: 301 GPGSICTTRVIAGIGVPQVTAIYDCATVAREYNIPIIADGGIKYSGEITKAIAAGASAVM 360 Query: 364 MGSLFAGTEESPGESEIYQGRKFKVYRGMGSMSAMKQGSKDRYFQDDDKKLVPEGIEGRV 423 +GSLFAGTEESPGESEIYQGR+FKVYRGMGSM+AMKQGSKDRYFQDDDKKLVPEGIEGRV Sbjct: 361 LGSLFAGTEESPGESEIYQGRRFKVYRGMGSMAAMKQGSKDRYFQDDDKKLVPEGIEGRV 420 Query: 424 AFKGSLSDTVHQLLGGLRSGMGYCGTKTLTELRNDTSFIRITGAGLRESHPHDVQITKEA 483 A+KG LSDTVHQLLGGLRSGMGYCGT + ELRNDTSFIRITGAGLRESHPHDVQITKEA Sbjct: 421 AYKGPLSDTVHQLLGGLRSGMGYCGTANIEELRNDTSFIRITGAGLRESHPHDVQITKEA 480 Query: 484 PNYSL 488 PNYSL Sbjct: 481 PNYSL 485 >B3KK85.1 B3KK85_9BACI Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 485 Score = 855 bits (2209), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/485 (84%), Positives = 447/485 (92%) Query: 4 VWEDKFGKEGLTFDDVLLVPRKSEVLPKEVDLSTVLSKNVKLNIPLMSAGMDTVTEXXXX 63 +WEDKF KEG TFDDVLLVPRKSEVLPKEVD+ST LS++VKLNIPL+SAGMDTVTE Sbjct: 1 MWEDKFSKEGFTFDDVLLVPRKSEVLPKEVDVSTKLSEHVKLNIPLISAGMDTVTEAPLA 60 Query: 64 XXXXXXXXXXXXHKNMSVEQQAEEVDRVKRSESGVITNPFSLTPDHWVSDAEVLMGKYRI 123 HKNM+VEQQAEEVDRVKRSESGVITNPFSL DH VSDAE LMGK+RI Sbjct: 61 IAIAREGGIGIIHKNMTVEQQAEEVDRVKRSESGVITNPFSLHADHLVSDAEKLMGKFRI 120 Query: 124 SGVPIVDEGNKLVGILTNRDLRFIHDFNIQIKEVMTHENLVTAAVGTTLQEAEVILQRHK 183 SGVPIVDE NKL+GILTNRDLRF+HD+N I EVMT ENLVTA VGTTLQ+AE+ILQ+HK Sbjct: 121 SGVPIVDENNKLIGILTNRDLRFVHDYNTVISEVMTSENLVTAPVGTTLQDAEMILQKHK 180 Query: 184 IEKLPLVDENNILKGLITIKDIEKAIQFPNGAKDAQGRLLVGAAIGISKDTFERTEALIK 243 IEKLPLVD++N+LKGLITIKDIEKAIQFP AKDAQGRLLVGAAIGISKDTFER EAL+K Sbjct: 181 IEKLPLVDDDNVLKGLITIKDIEKAIQFPRAAKDAQGRLLVGAAIGISKDTFERAEALVK 240 Query: 244 AGVDLITVDSAHGHHINIIDAVRKLRELYPDLTIVAGNVATGEATRELIEAGASVVKVGI 303 AGVD+ITVDSAHGHHINIID+VRKLRELYPDLTI+AGNVATGE TRELIEAGASVVKVGI Sbjct: 241 AGVDVITVDSAHGHHINIIDSVRKLRELYPDLTIIAGNVATGEGTRELIEAGASVVKVGI 300 Query: 304 GPGSICTTRVIAGIGVPQITAIYDCATVAREYGIPIIADGGIKYSGEITKAIAAGASAVM 363 GPGSICTTRVIAGIGVPQITAIYDCATVA+EYG+PIIADGGIKYSGEITKAIAAGASAVM Sbjct: 301 GPGSICTTRVIAGIGVPQITAIYDCATVAKEYGVPIIADGGIKYSGEITKAIAAGASAVM 360 Query: 364 MGSLFAGTEESPGESEIYQGRKFKVYRGMGSMSAMKQGSKDRYFQDDDKKLVPEGIEGRV 423 +GS+FAGTEESPGE+EIYQGR+FK YRGMGS++AMKQGSKDRYFQDDDKKLVPEGIEGRV Sbjct: 361 LGSMFAGTEESPGEAEIYQGRRFKAYRGMGSLAAMKQGSKDRYFQDDDKKLVPEGIEGRV 420 Query: 424 AFKGSLSDTVHQLLGGLRSGMGYCGTKTLTELRNDTSFIRITGAGLRESHPHDVQITKEA 483 A+KG L+DT+HQL+GGLRSGMGYCGT+ L ELRNDT FIRI+GAGLRESHPHD+QITKEA Sbjct: 421 AYKGPLADTIHQLIGGLRSGMGYCGTQNLEELRNDTQFIRISGAGLRESHPHDIQITKEA 480 Query: 484 PNYSL 488 PNYSL Sbjct: 481 PNYSL 485 >B1DKC5.1 B1DKC5_9BACL Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 485 Score = 808 bits (2087), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/485 (80%), Positives = 430/485 (88%) Query: 4 VWEDKFGKEGLTFDDVLLVPRKSEVLPKEVDLSTVLSKNVKLNIPLMSAGMDTVTEXXXX 63 +WE KF KEGLTFDDVLLVPRKS VLP+E D+ST LS+ +KLNIPL+SAGMDTVTE Sbjct: 1 MWETKFAKEGLTFDDVLLVPRKSVVLPRESDVSTKLSEGIKLNIPLISAGMDTVTESALA 60 Query: 64 XXXXXXXXXXXXHKNMSVEQQAEEVDRVKRSESGVITNPFSLTPDHWVSDAEVLMGKYRI 123 HKNMSV QQAEEVDRVKRSESGVITNPFSLTPDH V DAE LMGKYRI Sbjct: 61 IAIAREGGVGIIHKNMSVAQQAEEVDRVKRSESGVITNPFSLTPDHHVYDAEELMGKYRI 120 Query: 124 SGVPIVDEGNKLVGILTNRDLRFIHDFNIQIKEVMTHENLVTAAVGTTLQEAEVILQRHK 183 SGVPIVD KLVGILTNRDLRF+HD++I+I EVMT +LVTA VGTTLQEAE +LQ+HK Sbjct: 121 SGVPIVDSEQKLVGILTNRDLRFVHDYSIKINEVMTRTDLVTAPVGTTLQEAEGLLQKHK 180 Query: 184 IEKLPLVDENNILKGLITIKDIEKAIQFPNGAKDAQGRLLVGAAIGISKDTFERTEALIK 243 IEKLPLVDENN LKGLITIKDIEKAIQFPN AKD GRLL GAA+GI KDT +R +AL++ Sbjct: 181 IEKLPLVDENNTLKGLITIKDIEKAIQFPNAAKDKHGRLLCGAAVGIGKDTADRADALVQ 240 Query: 244 AGVDLITVDSAHGHHINIIDAVRKLRELYPDLTIVAGNVATGEATRELIEAGASVVKVGI 303 AG+D++ VDSAHGHHINI++AVRKLR YPDLTI+AGNVATGEATR+LIEAGASVVKVGI Sbjct: 241 AGIDVLVVDSAHGHHINILEAVRKLRAKYPDLTIIAGNVATGEATRDLIEAGASVVKVGI 300 Query: 304 GPGSICTTRVIAGIGVPQITAIYDCATVAREYGIPIIADGGIKYSGEITKAIAAGASAVM 363 GPGSICTTRVIAGIGVPQITAIYDCATVAREY +P+IADGGIKYSG+ITKAIAAGASA+M Sbjct: 301 GPGSICTTRVIAGIGVPQITAIYDCATVAREYNVPVIADGGIKYSGDITKAIAAGASAIM 360 Query: 364 MGSLFAGTEESPGESEIYQGRKFKVYRGMGSMSAMKQGSKDRYFQDDDKKLVPEGIEGRV 423 +GSLFAGT ESPGE+EI+QGR FKVYRGMGS+ AMK+GSKDRYFQ+++ KLVPEGIEGRV Sbjct: 361 IGSLFAGTAESPGETEIFQGRSFKVYRGMGSLGAMKEGSKDRYFQENESKLVPEGIEGRV 420 Query: 424 AFKGSLSDTVHQLLGGLRSGMGYCGTKTLTELRNDTSFIRITGAGLRESHPHDVQITKEA 483 FKG L+DTVHQLLGGLRSGMGYCGTK L ELRNDT FIRITG+GLRESHPHDVQITKEA Sbjct: 421 PFKGPLADTVHQLLGGLRSGMGYCGTKNLDELRNDTQFIRITGSGLRESHPHDVQITKEA 480 Query: 484 PNYSL 488 PNYSL Sbjct: 481 PNYSL 485 >C0ZH50.1 C0ZH50_BREBN Inosine-5'-monophosphate dehydrogenase EC=1.1.1.205 Length = 486 Score = 758 bits (1957), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/483 (74%), Positives = 418/483 (86%) Query: 6 EDKFGKEGLTFDDVLLVPRKSEVLPKEVDLSTVLSKNVKLNIPLMSAGMDTVTEXXXXXX 65 EDKF KEGLTFDDVLL+P KSEVLP++VDL LS+NVKLNIPL+SAGMDTVTE Sbjct: 3 EDKFVKEGLTFDDVLLIPGKSEVLPRDVDLRVQLSENVKLNIPLISAGMDTVTESGLAIA 62 Query: 66 XXXXXXXXXXHKNMSVEQQAEEVDRVKRSESGVITNPFSLTPDHWVSDAEVLMGKYRISG 125 HKNM++EQQA EVDRVKRSESGVITNPFSLT +H V +A LMGKYRISG Sbjct: 63 MARQGGIGIVHKNMTIEQQASEVDRVKRSESGVITNPFSLTQEHTVEEANALMGKYRISG 122 Query: 126 VPIVDEGNKLVGILTNRDLRFIHDFNIQIKEVMTHENLVTAAVGTTLQEAEVILQRHKIE 185 VPIVD KL+GILTNRDLRF+HDF+I+IKEVMT ENLVTA VGTTLQ+AE+ILQ+HKIE Sbjct: 123 VPIVDANQKLIGILTNRDLRFVHDFSIKIKEVMTKENLVTAPVGTTLQQAELILQQHKIE 182 Query: 186 KLPLVDENNILKGLITIKDIEKAIQFPNGAKDAQGRLLVGAAIGISKDTFERTEALIKAG 245 KLPLVDENN L+GLITIKDIEKAIQ+PN AKD QGRLL GAA+G+S DTFER AL++AG Sbjct: 183 KLPLVDENNTLRGLITIKDIEKAIQYPNAAKDNQGRLLCGAAVGVSADTFERAAALVQAG 242 Query: 246 VDLITVDSAHGHHINIIDAVRKLRELYPDLTIVAGNVATGEATRELIEAGASVVKVGIGP 305 VD++ +D+AHGH +I+ V+ +R+ YP LTIVAGNVATGEATR+LIEAGASVVKVGIGP Sbjct: 243 VDVLVIDTAHGHSKGVIETVKAVRKEYPTLTIVAGNVATGEATRDLIEAGASVVKVGIGP 302 Query: 306 GSICTTRVIAGIGVPQITAIYDCATVAREYGIPIIADGGIKYSGEITKAIAAGASAVMMG 365 GSICTTRV+AGIGVPQITAI+DCA VAREY IPIIADGGIKYSG++ KAI AGAS +M+G Sbjct: 303 GSICTTRVVAGIGVPQITAIHDCAQVAREYNIPIIADGGIKYSGDLPKAIGAGASVIMIG 362 Query: 366 SLFAGTEESPGESEIYQGRKFKVYRGMGSMSAMKQGSKDRYFQDDDKKLVPEGIEGRVAF 425 SLFAGTEESPGE EI+QGR+FKVYRGMGS+ AMK GSKDRYFQ++ +KLVPEGIEGRV + Sbjct: 363 SLFAGTEESPGEFEIFQGRRFKVYRGMGSIGAMKAGSKDRYFQENAQKLVPEGIEGRVPY 422 Query: 426 KGSLSDTVHQLLGGLRSGMGYCGTKTLTELRNDTSFIRITGAGLRESHPHDVQITKEAPN 485 KG L+D +QL+GGLR+GMGYCG KT+ +L ++ F+RITGAGLRESHPHDVQITKE+PN Sbjct: 423 KGPLADVTYQLIGGLRAGMGYCGAKTIEDLIQNSQFVRITGAGLRESHPHDVQITKESPN 482 Query: 486 YSL 488 YS+ Sbjct: 483 YSI 485 >C5D335.1 C5D335_9BACI Inosine-5'-monophosphate dehydrogenase EC=1.1.1.37 Length = 488 Score = 738 bits (1905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/487 (71%), Positives = 419/487 (86%), Gaps = 2/487 (0%) Query: 4 VWEDKFGKEGLTFDDVLLVPRKSEVLPKEVDLSTVLSKNVKLNIPLMSAGMDTVTEXXXX 63 +WE KF KEGLTFDDVLL+P KS+VLP++VD++T LS+ ++LNIP++SAGMDTVTE Sbjct: 1 MWESKFAKEGLTFDDVLLIPAKSDVLPRDVDVTTKLSETLQLNIPIISAGMDTVTEAEMA 60 Query: 64 XXXXXXXXXXXXHKNMSVEQQAEEVDRVKRSESGVITNPFSLTPDHWVSDAEVLMGKYRI 123 HKNMS+EQQAE+VD+VKRSE GVIT+PF LTP+H V DAE LM KYRI Sbjct: 61 IAMARQGGLGIIHKNMSIEQQAEQVDKVKRSERGVITDPFFLTPEHQVYDAEHLMSKYRI 120 Query: 124 SGVPIVD--EGNKLVGILTNRDLRFIHDFNIQIKEVMTHENLVTAAVGTTLQEAEVILQR 181 SGVPIV+ E KLVGI+TNRDLRFI D++I+I +VMT ENL+TA VGTTL+EAE ILQ+ Sbjct: 121 SGVPIVNNEEEQKLVGIITNRDLRFIQDYSIKIADVMTKENLITAPVGTTLEEAEKILQK 180 Query: 182 HKIEKLPLVDENNILKGLITIKDIEKAIQFPNGAKDAQGRLLVGAAIGISKDTFERTEAL 241 +K+EKLPLVDEN +LKGLITIKDIEK I+FPN AKDA+GRLLVGAA+G++ DT R + L Sbjct: 181 YKVEKLPLVDENGVLKGLITIKDIEKVIEFPNSAKDAKGRLLVGAAVGVTADTMIRVKKL 240 Query: 242 IKAGVDLITVDSAHGHHINIIDAVRKLRELYPDLTIVAGNVATGEATRELIEAGASVVKV 301 ++A VD+I VD+AHGH +++ VRK+RE YPDL I+AGNVAT EATR+LIEAGA+++KV Sbjct: 241 VEANVDVIVVDTAHGHSKGVLETVRKIREQYPDLNIIAGNVATAEATRDLIEAGANIIKV 300 Query: 302 GIGPGSICTTRVIAGIGVPQITAIYDCATVAREYGIPIIADGGIKYSGEITKAIAAGASA 361 GIGPGSICTTRV+AG+GVPQITAIYDCAT AR+YG+PIIADGGIKYSG+I KA+AAGA A Sbjct: 301 GIGPGSICTTRVVAGVGVPQITAIYDCATEARKYGVPIIADGGIKYSGDIVKALAAGAHA 360 Query: 362 VMMGSLFAGTEESPGESEIYQGRKFKVYRGMGSMSAMKQGSKDRYFQDDDKKLVPEGIEG 421 VM+GSL AG ESPGE+EIYQGR+FKVYRGMGS++AM++GSKDRYFQ+D+KK VPEGIEG Sbjct: 361 VMLGSLLAGVSESPGETEIYQGRRFKVYRGMGSVAAMEKGSKDRYFQEDNKKFVPEGIEG 420 Query: 422 RVAFKGSLSDTVHQLLGGLRSGMGYCGTKTLTELRNDTSFIRITGAGLRESHPHDVQITK 481 RV +KG L+DT++QL+GGLR+GMGYCGT+ L ELR T FIR+T AGLRESHPHDVQITK Sbjct: 421 RVPYKGPLADTIYQLVGGLRAGMGYCGTRNLEELREKTQFIRMTSAGLRESHPHDVQITK 480 Query: 482 EAPNYSL 488 EAPNYSL Sbjct: 481 EAPNYSL 487 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.135 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,759,730,565 Number of extensions: 115356729 Number of successful extensions: 386218 Number of sequences better than 1.0e-05: 2593 Number of HSP's gapped: 378280 Number of HSP's successfully gapped: 2672 Length of query: 488 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 348 Effective length of database: 1,741,754,103 Effective search space: 606130427844 Effective search space used: 606130427844 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)