BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0063.0005.p (465 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KK86.1 B3KK86_9BACI Serine-type D-Ala-D-Ala carboxypeptidase E... 585 e-165 B2BCX1.1 B2BCX1_PAEPO D-ala-D-ala carboxypeptidase 539 e-151 B1DKC4.1 B1DKC4_9BACL Serine-type D-Ala-D-Ala carboxypeptidase E... 368 e-100 C2Q5G4.1 C2Q5G4_BACCE D-Ala-D-Ala carboxypeptidase A; Serine pep... 300 3e-79 C2W2N4.1 C2W2N4_BACCE D-Ala-D-Ala carboxypeptidase A; Serine pep... 299 4e-79 >B3KK86.1 B3KK86_9BACI Serine-type D-Ala-D-Ala carboxypeptidase EC=3.4.16.4 Length = 472 Score = 585 bits (1508), Expect = e-165, Method: Compositional matrix adjust. Identities = 290/466 (62%), Positives = 349/466 (74%), Gaps = 14/466 (3%) Query: 10 KQFVMKTATVGLLLNIL----------ASPVNSALADAVKTPATTESGXXXXXXXXXXXX 59 +Q + +T +L NIL A+P A AD K TE Sbjct: 11 RQRIQRTLASLMLFNILCFSAAPAVSLAAPNMLATADTTKA---TEDKAATDKAATNNAK 67 Query: 60 XXXIPSVESLGLKLRSAVLLEPTTGEVLLSLNADVPLPPASMTKMMTEYLVTEAVNKGQL 119 +PSV+ LGL++ SAVL+EP+TG+VLLS+NAD LPPASMTKMMTEY+V E V +G+L Sbjct: 68 PDKVPSVDQLGLEVSSAVLIEPSTGQVLLSINADEALPPASMTKMMTEYIVAEKVKQGEL 127 Query: 120 SWDQKVVVQENASKQIGSRIFLAQGDEHTVKELYIAMAVGSANDATVALAEEVAGSEQEF 179 +WD V V ENA K +GSRIFLA+GD+HTV+ELYIAMAVGSANDATVALAE VAGSE EF Sbjct: 128 AWDDVVTVGENAEKTVGSRIFLAEGDQHTVEELYIAMAVGSANDATVALAEHVAGSEAEF 187 Query: 180 VAMMNETAQKMGMKTAYFINSTGLNRADMPAKFQPDTDRETVMSAMDAAILAKHIVTDHP 239 V MMN+TA+KMG+KTA+FINSTGL+RADMP K++P D+ETVMSAMD A+LAK+IV DHP Sbjct: 188 VTMMNDTAKKMGLKTAFFINSTGLSRADMPEKYRPAEDKETVMSAMDTALLAKYIVEDHP 247 Query: 240 DFTDFTTIQSYKFRDRDKAPMINYNWMLEANKNVTNFKAYAYPGLDGLKTGHTNDAGNCF 299 DF FT IQS+KFR RD +P+INYNWMLEANK++TNFKAYAY GLDGLKTGHTN AG CF Sbjct: 248 DFAKFTAIQSHKFRPRDTSPIINYNWMLEANKSITNFKAYAYEGLDGLKTGHTNAAGYCF 307 Query: 300 TGTAVRDGMRLISVVMGADSEPHRFTETKKVLDFGFNNFEVKQVVAPKAVIAGNETVPVL 359 GTA RDGMRLISVVMG SE RF ETKKVLD+GF+NFEVK+V A A + G ETV V Sbjct: 308 AGTAERDGMRLISVVMGTKSEGARFKETKKVLDYGFDNFEVKEVQAAGATVQGFETVEVK 367 Query: 360 KGKNKTVPVVTDAGVTFIVPKGTASPQIKTAVVINDPATLVAPIAGASKVGKVTYSYQVE 419 KGK K +VTD +TF+VPKG++ I + D +++ AP+A +KVG TYSY++E Sbjct: 368 KGKGKEAGLVTDKALTFVVPKGSSGKNITFEAKL-DSSSVTAPVAKDTKVGTATYSYKIE 426 Query: 420 GITQVQEKTVNLITAEEAEKAGWFKLLMRAIGEFFGDLFKGIKNLF 465 G+ + Q +TVNLITA+E EKAGWFKL +RAIG+FF DLF IKNLF Sbjct: 427 GMKETQTETVNLITADEVEKAGWFKLFLRAIGDFFADLFDSIKNLF 472 >B2BCX1.1 B2BCX1_PAEPO D-ala-D-ala carboxypeptidase Length = 417 Score = 539 bits (1388), Expect = e-151, Method: Compositional matrix adjust. Identities = 252/364 (69%), Positives = 300/364 (82%) Query: 65 SVESLGLKLRSAVLLEPTTGEVLLSLNADVPLPPASMTKMMTEYLVTEAVNKGQLSWDQK 124 S+ L LRSA+L+EP+TG+VLLS+N D PLPPASMTKMMTEY+V E V +G+L W K Sbjct: 33 SINPPSLALRSAILIEPSTGQVLLSMNPDEPLPPASMTKMMTEYIVAEQVKQGKLKWTDK 92 Query: 125 VVVQENASKQIGSRIFLAQGDEHTVKELYIAMAVGSANDATVALAEEVAGSEQEFVAMMN 184 V V ENASK IGSRIFLAQGD+HTV+ELYIAMAVGSANDATVALAE V+G+EQ+FV +MN Sbjct: 93 VTVNENASKSIGSRIFLAQGDQHTVEELYIAMAVGSANDATVALAERVSGTEQDFVKLMN 152 Query: 185 ETAQKMGMKTAYFINSTGLNRADMPAKFQPDTDRETVMSAMDAAILAKHIVTDHPDFTDF 244 ETAQKMGMK YFINSTGL+R DMP FQPDTDRETVM+A DAA LA +I+ DHPD+T F Sbjct: 153 ETAQKMGMKNTYFINSTGLDRKDMPTGFQPDTDRETVMTARDAATLAGYIIKDHPDYTRF 212 Query: 245 TTIQSYKFRDRDKAPMINYNWMLEANKNVTNFKAYAYPGLDGLKTGHTNDAGNCFTGTAV 304 TTIQSYKFR DKAP+INYNWMLE NKN+TNF+ +AYPGLDG+KTGHTN+AGNCFTGTA Sbjct: 213 TTIQSYKFRPTDKAPIINYNWMLEENKNITNFRKFAYPGLDGMKTGHTNNAGNCFTGTAE 272 Query: 305 RDGMRLISVVMGADSEPHRFTETKKVLDFGFNNFEVKQVVAPKAVIAGNETVPVLKGKNK 364 R+GMRLISVVMGADS+ HRFTET KVL++GF+NFEVKQVVAPK V+ G E VPV KG Sbjct: 273 RNGMRLISVVMGADSDAHRFTETAKVLNYGFDNFEVKQVVAPKTVVKGVENVPVTKGTET 332 Query: 365 TVPVVTDAGVTFIVPKGTASPQIKTAVVINDPATLVAPIAGASKVGKVTYSYQVEGITQV 424 VP+VT V+FIVPKG ++P++ I ++LVAP+ +KVG +TY+Y+ +G+ + Sbjct: 333 EVPIVTKDAVSFIVPKGASNPKVTFTTNITPASSLVAPLKQGAKVGTITYTYKTDGVDKG 392 Query: 425 QEKT 428 Q KT Sbjct: 393 QTKT 396 >B1DKC4.1 B1DKC4_9BACL Serine-type D-Ala-D-Ala carboxypeptidase EC=3.4.16.4 Length = 428 Score = 368 bits (944), Expect = e-100, Method: Compositional matrix adjust. Identities = 191/401 (47%), Positives = 267/401 (66%), Gaps = 18/401 (4%) Query: 68 SLGLKLRSAVLLEPTTGEVLLSLNADVPLPPASMTKMMTEYLVTEAVNKGQLSWDQKVVV 127 SLGL+L SA+L++ TG+V+ +NAD P PPASMTKMMTEY+V E + L+WD+ + V Sbjct: 43 SLGLELSSAILIDADTGQVVYEVNADEPRPPASMTKMMTEYIVLEQIKSKALNWDEMITV 102 Query: 128 QENASK--QIGSRIFLAQGDEHTVKELYIAMAVGSANDATVALAEEVAGSEQEFVAMMNE 185 E A+ + GS+++LAQG+++ VK+LY+AMAVGSANDAT+ALA + GSEQ FV MNE Sbjct: 103 SEEAANTPKDGSQVYLAQGEQYKVKDLYMAMAVGSANDATIALASAIGGSEQGFVEKMNE 162 Query: 186 TAQKMGMKTAYFINSTGLNRADMPAKFQPDTDRETVMSAMDAAILAKHIVTDHPDFTDFT 245 TAQK+G+ +A++ ++TGL DT TV+SA D A LA+ I+ + P+F ++ Sbjct: 163 TAQKLGLTSAHYTSATGL----------ADT---TVISAKDQAKLAQIIIKNDPEFLEYA 209 Query: 246 TIQSYKFRDRDKAPMINYNWMLEANKNVTNFKAYAYPGLDGLKTGHTNDAGNCFTGTAVR 305 + YKFR RD P++N NWML +NK+ T KA+AY G+DG+KTG+ + AG FTGT R Sbjct: 210 STTEYKFRPRDDKPIVNINWMLASNKSNTYLKAFAYDGVDGMKTGYISAAGYTFTGTVKR 269 Query: 306 DGMRLISVVMGADSEPHRFTETKKVLDFGFNNFEVKQVVAPKAVIAGNETVPVLKGKNKT 365 R ISVVM S+ RF ET K+ ++ FN+ E K V+ K+V+ E+V + KG K+ Sbjct: 270 GDQRYISVVMNTKSKEARFNETAKLYNYAFNSLEKKTVIPAKSVVEKAESVKIKKGVKKS 329 Query: 366 VPVVTDAGVTFIVPKGTASPQIK-TAVVINDPATLVAPIAGASKVGKVTYSYQVEGITQV 424 VP++T++ ++ IV KG A P+++ T + P LVAPI VG TY Y E + Sbjct: 330 VPIITESDISLIVKKG-ADPKVELTGYELKKPEELVAPIKAGQVVGTATYKYTDEQ-GKA 387 Query: 425 QEKTVNLITAEEAEKAGWFKLLMRAIGEFFGDLFKGIKNLF 465 EKTVNLI +++ +KA WF L+ R IG FF LF GI +LF Sbjct: 388 LEKTVNLIASKDVKKASWFALMFRGIGGFFSGLFNGIVDLF 428 >C2Q5G4.1 C2Q5G4_BACCE D-Ala-D-Ala carboxypeptidase A; Serine peptidase; MEROPS family S11 Length = 442 Score = 300 bits (767), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 180/405 (44%), Positives = 234/405 (57%), Gaps = 20/405 (4%) Query: 65 SVESLGLKLRSAVLLEPTTGEVLLSLNADVPLPPASMTKMMTEYLVTEAVNKGQLSWDQK 124 +V +L ++ SA+L+E +G++L NAD L ASMTKMM+EYLV EAV+KG+L WDQK Sbjct: 38 TVPALDVEAGSAILVEANSGKILYQKNADELLAIASMTKMMSEYLVHEAVDKGKLKWDQK 97 Query: 125 VVVQENASKQIGSR----IFLAQGDEHTVKELYIAMAVGSANDATVALAEEVAGSEQEFV 180 V + E A K R + L G +TVKELY AM + SAN AT+ALAEE+AG E FV Sbjct: 98 VKISEYAYKISQDRSLSNVPLENGGSYTVKELYEAMVIYSANGATIALAEEIAGKEVNFV 157 Query: 181 AMMNETAQKMGMKTAYFINSTGLNRADMPAKFQPDT--DRETVMSAMDAAILAKHIVTDH 238 MMN+ +++ GMK F+NSTGL D+ T D + MSA D AILA+ ++ D Sbjct: 158 KMMNDKSKEFGMKNYKFVNSTGLTNHDLKGHHPEGTTPDEKNKMSARDCAILAQRLIQDF 217 Query: 239 PDFTDFTTIQSYKFRDRDKAP--MINYNWMLEANKNVTNFKAYAYPGLDGLKTGHTNDAG 296 P D I F+ K P M N+NWML+ Y G+DGLKTG T +AG Sbjct: 218 PKILDTAKIPKKTFQKGGKYPIDMTNFNWMLKG-------LIKQYEGVDGLKTGTTPEAG 270 Query: 297 NCFTGTAVRDGMRLISVVMGADSEPHRFTETKKVLDFGFNNFEVKQVVAPKAVIAGNETV 356 +CFTGT R+GMRLISVV+ A S RF ETKK+ D+GF NFEVK+V +V+ G+ETV Sbjct: 271 DCFTGTVERNGMRLISVVIKASSHTARFDETKKLYDYGFANFEVKKVYEKDSVVKGHETV 330 Query: 357 PVLKGKNKTVPVVTDAGVTFIVPKGTASPQIKTAVVINDPATLVAPIAGASKVGKVTYSY 416 V K+K V V V+ +PKG K V N API + K+T S Sbjct: 331 RVANAKDKDVVVQAKQAVSLPMPKGNKDVYKKEFKVSNKEQE--APIKKDVTISKMTISP 388 Query: 417 QVE---GITQVQEKTVNLITAEEAEKAGWFKLLMRAIGEFFGDLF 458 + G + V+L+T E E+A WF LMR IG FF ++ Sbjct: 389 KDSTDPGFLSGKSLQVDLVTKSEVEQANWFTRLMREIGSFFSGMW 433 >C2W2N4.1 C2W2N4_BACCE D-Ala-D-Ala carboxypeptidase A; Serine peptidase; MEROPS family S11 Length = 449 Score = 299 bits (765), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 176/396 (44%), Positives = 234/396 (59%), Gaps = 22/396 (5%) Query: 75 SAVLLEPTTGEVLLSLNADVPLPPASMTKMMTEYLVTEAVNKGQLSWDQKVVVQENASKQ 134 +A+L+E +G++L NAD L ASMTKMM+EYLV +AV++G+L WDQKV V E A K Sbjct: 53 AAILVEADSGKILYQKNADELLAIASMTKMMSEYLVHKAVDQGKLKWDQKVKVSEYAYKV 112 Query: 135 IGSR----IFLAQGDEHTVKELYIAMAVGSANDATVALAEEVAGSEQEFVAMMNETAQKM 190 R + L G +TVKELY AMA+ SAN AT+ALAE VAG E +FV MMN+ A++ Sbjct: 113 SQDRSLSNVPLENGGSYTVKELYEAMAIYSANGATIALAEAVAGKEADFVKMMNDQAKEF 172 Query: 191 GMKTAYFINSTGLNRADMPAKFQPDT---DRETVMSAMDAAILAKHIVTDHPDFTDFTTI 247 G+K F+NSTGL D+ P+ D E MSA D AILA+ ++ D P+ D I Sbjct: 173 GLKNYKFVNSTGLTNTDLKG-LHPEGTTPDEENKMSARDVAILAQRLMQDFPNVLDTAKI 231 Query: 248 QSYKFRDRDKAP--MINYNWMLEANKNVTNFKAYAYPGLDGLKTGHTNDAGNCFTGTAVR 305 F+ K P M N+NWML+ Y G+DGLKTGHT +AG CFTGTA + Sbjct: 232 PKKVFQKDGKYPIQMDNWNWMLKG-------LVKQYEGVDGLKTGHTPEAGYCFTGTAEK 284 Query: 306 DGMRLISVVMGADSEPHRFTETKKVLDFGFNNFEVKQVVAPKAVIAGNETVPVLKGKNKT 365 +GMRLISVV+ S RF ETKK+ D+GF NF+VK+V + + + G+ETV V K+K Sbjct: 285 NGMRLISVVINTSSNTSRFDETKKIFDYGFANFDVKKVYSKGSAVKGHETVRVENAKDKD 344 Query: 366 VPVVTDAGVTFIVPKGTASPQIKTAVVINDPATLVAPIAGASKVGKVTYSYQVE---GIT 422 V V T +T +PKG S + + API + +G++ S + G Sbjct: 345 VTVQTKQAITLPMPKG--SKDVYKTEFKDTSKEKEAPIKKGTTLGQMVISPKDTNDPGFL 402 Query: 423 QVQEKTVNLITAEEAEKAGWFKLLMRAIGEFFGDLF 458 + V+L+T E EKA WF MR IG FFGD++ Sbjct: 403 SGKSLQVDLVTKAEVEKANWFTRSMRGIGSFFGDIW 438 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.130 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,477,426,391 Number of extensions: 97897648 Number of successful extensions: 277823 Number of sequences better than 1.0e-05: 3123 Number of HSP's gapped: 270930 Number of HSP's successfully gapped: 3140 Length of query: 465 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 326 Effective length of database: 1,751,175,118 Effective search space: 570883088468 Effective search space used: 570883088468 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)