BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0060.0014.p (573 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K908.1 B3K908_9BACI Anthranilate synthase EC=4.1.3.27 662 0.0 C2W2T6.1 C2W2T6_BACCE Para-aminobenzoate synthase component 1 428 e-118 C2WXP7.1 C2WXP7_BACCE Para-aminobenzoate synthase component 1 424 e-117 C2V5V1.1 C2V5V1_BACCE Para-aminobenzoate synthase component 1 424 e-117 C2TRC3.1 C2TRC3_BACCE Para-aminobenzoate synthase component 1 424 e-117 >B3K908.1 B3K908_9BACI Anthranilate synthase EC=4.1.3.27 Length = 554 Score = 662 bits (1708), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/541 (62%), Positives = 389/541 (71%), Gaps = 43/541 (7%) Query: 48 WEQWAQEKWSLLPLIIRTPQDKGGLPASWMKAWELASPYSVVLESGKGGRYTYLGLHPVS 107 W+ WA+E WS++P +++ GLP SW AW+ ASPY+ VLESGKGGRYTYLGL PVS Sbjct: 10 WQSWAKEGWSVVPYLVQYKGATQGLPLSWRHAWKEASPYAFVLESGKGGRYTYLGLRPVS 69 Query: 108 VLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEMLELWMKDFTSPRVQVTELPPFIG 167 +LQGK E+ L T TG PL +LE WMK + SPRV P F G Sbjct: 70 ILQGKGSQGEVVEMSGG--------LRTQVTGEPLRLLEQWMKAWKSPRV--PGWPDFRG 119 Query: 168 GCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEELWTYDHQEDMLYCTVHVPVPAAA 227 GC GFLSYDV+RS+E+LPV AKD+PGFPDYL+MR+EE+W YDH ++ LYC+VHVP+P A Sbjct: 120 GCAGFLSYDVIRSIEQLPVMAKDEPGFPDYLWMRMEEVWIYDHTDESLYCSVHVPLPWAF 179 Query: 228 QSSGPAE------------------------LKDLYQKASRRAERMLEQWRQISAAPGNS 263 S ++ L++LY+KA RAE ML QW Q+ + Sbjct: 180 GSGEDSKEATALEDSADVSEGSELSLGQEEILEELYEKAGLRAESMLSQWNQMYGTGSEN 239 Query: 264 XXXXXXXXX-----XXXXXVSGE----WPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVN 314 +SG W + F E F+QAV +QEYIRQGDVFQVN Sbjct: 240 DSKSEDERVRQERWKKAQELSGPNVEVWDRLEIDFSQEAFEQAVLSIQEYIRQGDVFQVN 299 Query: 315 LSLRQEAQLNSSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPI 374 LSLR+ QL++ P D+YEWLR LNPSPYMG L SP F+LAS SPELLV+L GD VSARPI Sbjct: 300 LSLRRHLQLHAEPSDIYEWLRILNPSPYMGYLSSPGFSLASGSPELLVKLDGDIVSARPI 359 Query: 375 AGTRRRGLTPAEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVER 434 AGTRRRG P EDAAMEAEL GSEKE AEHIMLVDLERNDIGR+AAYGTV VPEL+TVER Sbjct: 360 AGTRRRGRNPEEDAAMEAELLGSEKERAEHIMLVDLERNDIGRIAAYGTVHVPELMTVER 419 Query: 435 YSHVMHLVSQVEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGS 494 YSHVMHLVSQVEG +A G AYDV+AA FPGGTITGAPK+RTMEIIEELEPV RGPYTGS Sbjct: 420 YSHVMHLVSQVEGRIAEGNNAYDVIAAAFPGGTITGAPKIRTMEIIEELEPVTRGPYTGS 479 Query: 495 MGWIDYNGNMELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLC 554 MGWIDYNG+MELNIIIRTLAVKDG+GYIQTGAGIVIDSDPYREYRECHNKAKA++ A++C Sbjct: 480 MGWIDYNGDMELNIIIRTLAVKDGVGYIQTGAGIVIDSDPYREYRECHNKAKALIAALMC 539 Query: 555 S 555 S Sbjct: 540 S 540 >C2W2T6.1 C2W2T6_BACCE Para-aminobenzoate synthase component 1 Length = 474 Score = 428 bits (1101), Expect = e-118, Method: Compositional matrix adjust. Identities = 226/471 (47%), Positives = 295/471 (62%), Gaps = 43/471 (9%) Query: 88 VVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEMLEL 147 ++LESG+GGRY+ +GL PV+ +QGK T I E ET G+PL++++ Sbjct: 41 ILLESGRGGRYSIVGLDPVATIQGKNETLYIR----------ESGKETIERGNPLDLMQK 90 Query: 148 WMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEELWT 207 +M+ + + +E PPF GG IG+ SYD +R +EKLP +AKDD PD F+ ++++ Sbjct: 91 YMEKWKTE--HNSEYPPFQGGAIGYFSYDCIRYIEKLPSFAKDDVDIPDIFFLLFDDVFV 148 Query: 208 YDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQ--ISAAPGNSXX 265 YD QE++L+ H Y AE L +W+ + AP Sbjct: 149 YDQQEEVLWIITH------------------YIDEHEEAESRLNEWKNLWVKEAP----- 185 Query: 266 XXXXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLNS 325 S E AF E F +AV+ +QEYI GDVFQVNLS RQE L + Sbjct: 186 ------EVKVPFESPENKKDAVAFTEENFMEAVQRIQEYIGAGDVFQVNLSTRQEKTLQT 239 Query: 326 SPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTPA 385 P ++Y+ LR++NPSPYMG L F + S SPELL++ G++VS RPIAGTR RG Sbjct: 240 HPLEIYKSLREINPSPYMGYLELGNFQIVSGSPELLIKKQGNEVSTRPIAGTRSRGKNEQ 299 Query: 386 EDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQV 445 ED ++ EL +EKE AEH+MLVDLERND+GRV YGTV V E + +E+YSHVMH+VS V Sbjct: 300 EDESLAKELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSNV 359 Query: 446 EGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNME 505 G V K A+D++ A+FPGGTITGAPK+RTMEIIEELEPVRRG YTGS+GWI Y+G+ME Sbjct: 360 RGEVESDKDAFDLVRAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDME 419 Query: 506 LNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSE 556 LNI+IRTL K G Y+Q GAGIVIDS+P EY+E KA A+ +A SE Sbjct: 420 LNIVIRTLLAKGGQAYVQAGAGIVIDSNPKNEYKESLKKAIALWRAKESSE 470 >C2WXP7.1 C2WXP7_BACCE Para-aminobenzoate synthase component 1 Length = 465 Score = 424 bits (1091), Expect = e-117, Method: Compositional matrix adjust. Identities = 226/472 (47%), Positives = 291/472 (61%), Gaps = 39/472 (8%) Query: 85 PYSVVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEM 144 P ++LESG+GGRY +GL+PV+V+QGK T I E ET + G+PL++ Sbjct: 29 PQHILLESGRGGRYNIVGLNPVAVIQGKGETLHI----------SESGKETIKRGNPLDL 78 Query: 145 LELWMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEE 204 ++ +M+ + + E PPF GG IG+ SYD +R +EKLP A+DD PD F+ ++ Sbjct: 79 MQEYMEKWKTD--YNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDLNIPDIFFLLFDD 136 Query: 205 LWTYDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSX 264 ++ YD +E +L+ H Y AE L +W+ + AA Sbjct: 137 VFVYDQEEKVLWIITH------------------YVDKHAEAEERLHEWKNLWAAEVPEV 178 Query: 265 XXXXXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLN 324 V AF E F +AV +QEYI GDVFQVNLS RQE L Sbjct: 179 TMPFERPEKKNEAV---------AFTEEGFMKAVERIQEYIGNGDVFQVNLSTRQERTLQ 229 Query: 325 SSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTP 384 + P ++Y LRK+NPSPYMG L F + SASPELL++ G +VS RPIAGTR RG Sbjct: 230 THPLEIYTSLRKINPSPYMGYLELGDFQIVSASPELLIKKQGQEVSTRPIAGTRSRGANE 289 Query: 385 AEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQ 444 ED + EL +EKE AEH+MLVDLERND+GRV YGTV V E + +E+YSHVMH+VS Sbjct: 290 QEDEELARELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSN 349 Query: 445 VEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNM 504 V G V K A+D++ A+FPGGTITGAPK+RTMEIIEELEPVRRG YTGS+GWI Y+G+ Sbjct: 350 VRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDT 409 Query: 505 ELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSE 556 ELNI+IRTL KDG ++Q GAGIVIDS+P EY+E KA A+ +A SE Sbjct: 410 ELNIVIRTLLAKDGQAHVQAGAGIVIDSNPKNEYKESLKKAIALWRAKESSE 461 >C2V5V1.1 C2V5V1_BACCE Para-aminobenzoate synthase component 1 Length = 465 Score = 424 bits (1091), Expect = e-117, Method: Compositional matrix adjust. Identities = 226/472 (47%), Positives = 291/472 (61%), Gaps = 39/472 (8%) Query: 85 PYSVVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEM 144 P ++LESG+GGRY +GL+PV+V+QGK T I E ET + G+PL++ Sbjct: 29 PQHILLESGRGGRYNIVGLNPVAVIQGKGETLHI----------SESGKETIKRGNPLDL 78 Query: 145 LELWMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEE 204 ++ +M+ + + E PPF GG IG+ SYD +R +EKLP A+DD PD F+ ++ Sbjct: 79 MQEYMEKWKTD--YNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDLNIPDIFFLLFDD 136 Query: 205 LWTYDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSX 264 ++ YD +E +L+ H Y AE L +W+ + AA Sbjct: 137 VFVYDQEEKVLWIITH------------------YVDKHAEAEERLHEWKNLWAAEVPEV 178 Query: 265 XXXXXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLN 324 V AF E F +AV +QEYI GDVFQVNLS RQE L Sbjct: 179 TMPFERPEKKNEAV---------AFTEEGFMKAVERIQEYIGNGDVFQVNLSTRQERTLQ 229 Query: 325 SSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTP 384 + P ++Y LRK+NPSPYMG L F + SASPELL++ G +VS RPIAGTR RG Sbjct: 230 THPLEIYTSLRKINPSPYMGYLELGDFQIVSASPELLIKKQGQEVSTRPIAGTRSRGANE 289 Query: 385 AEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQ 444 ED + EL +EKE AEH+MLVDLERND+GRV YGTV V E + +E+YSHVMH+VS Sbjct: 290 QEDEELARELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSN 349 Query: 445 VEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNM 504 V G V K A+D++ A+FPGGTITGAPK+RTMEIIEELEPVRRG YTGS+GWI Y+G+ Sbjct: 350 VRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDT 409 Query: 505 ELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSE 556 ELNI+IRTL KDG ++Q GAGIVIDS+P EY+E KA A+ +A SE Sbjct: 410 ELNIVIRTLLAKDGQAHVQAGAGIVIDSNPKNEYKESLKKAIALWRAKESSE 461 >C2TRC3.1 C2TRC3_BACCE Para-aminobenzoate synthase component 1 Length = 465 Score = 424 bits (1091), Expect = e-117, Method: Compositional matrix adjust. Identities = 226/472 (47%), Positives = 291/472 (61%), Gaps = 39/472 (8%) Query: 85 PYSVVLESGKGGRYTYLGLHPVSVLQGKAGTAEIYSFPSDAAGTVEPLLETSRTGHPLEM 144 P ++LESG+GGRY +GL+PV+V+QGK T I E ET + G+PL++ Sbjct: 29 PQHILLESGRGGRYNIVGLNPVAVIQGKGETLHI----------SESGKETIKRGNPLDL 78 Query: 145 LELWMKDFTSPRVQVTELPPFIGGCIGFLSYDVVRSLEKLPVWAKDDPGFPDYLFMRLEE 204 ++ +M+ + + E PPF GG IG+ SYD +R +EKLP A+DD PD F+ ++ Sbjct: 79 MQEYMEKWKTD--YNPEYPPFQGGAIGYFSYDCIRYIEKLPSLAEDDLNIPDIFFLLFDD 136 Query: 205 LWTYDHQEDMLYCTVHVPVPAAAQSSGPAELKDLYQKASRRAERMLEQWRQISAAPGNSX 264 ++ YD +E +L+ H Y AE L +W+ + AA Sbjct: 137 VFVYDQEEKVLWIITH------------------YVDKHAEAEERLHEWKNLWAAEVPEV 178 Query: 265 XXXXXXXXXXXXXVSGEWPGMTTAFPPEQFQQAVREVQEYIRQGDVFQVNLSLRQEAQLN 324 V AF E F +AV +QEYI GDVFQVNLS RQE L Sbjct: 179 TMPFERPEKKNEAV---------AFTEEGFMKAVERIQEYIGNGDVFQVNLSTRQERTLQ 229 Query: 325 SSPEDVYEWLRKLNPSPYMGLLRSPRFALASASPELLVRLHGDKVSARPIAGTRRRGLTP 384 + P ++Y LRK+NPSPYMG L F + SASPELL++ G +VS RPIAGTR RG Sbjct: 230 THPLEIYTSLRKINPSPYMGYLELGDFQIVSASPELLIKKQGQEVSTRPIAGTRSRGANE 289 Query: 385 AEDAAMEAELRGSEKEIAEHIMLVDLERNDIGRVAAYGTVSVPELLTVERYSHVMHLVSQ 444 ED + EL +EKE AEH+MLVDLERND+GRV YGTV V E + +E+YSHVMH+VS Sbjct: 290 QEDEELARELIENEKERAEHVMLVDLERNDLGRVCKYGTVEVDEFMVIEKYSHVMHIVSN 349 Query: 445 VEGTVAPGKGAYDVMAALFPGGTITGAPKVRTMEIIEELEPVRRGPYTGSMGWIDYNGNM 504 V G V K A+D++ A+FPGGTITGAPK+RTMEIIEELEPVRRG YTGS+GWI Y+G+ Sbjct: 350 VRGEVEEDKDAFDLVKAVFPGGTITGAPKIRTMEIIEELEPVRRGIYTGSIGWIGYSGDT 409 Query: 505 ELNIIIRTLAVKDGIGYIQTGAGIVIDSDPYREYRECHNKAKAVVKAVLCSE 556 ELNI+IRTL KDG ++Q GAGIVIDS+P EY+E KA A+ +A SE Sbjct: 410 ELNIVIRTLLAKDGQAHVQAGAGIVIDSNPKNEYKESLKKAIALWRAKESSE 461 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,557,985,376 Number of extensions: 157053659 Number of successful extensions: 346681 Number of sequences better than 1.0e-05: 3770 Number of HSP's gapped: 341424 Number of HSP's successfully gapped: 3874 Length of query: 573 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 432 Effective length of database: 1,732,333,088 Effective search space: 748367894016 Effective search space used: 748367894016 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)