BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0057.0016.p (538 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8R925.1 Q8R925_THETN Phosphorylase EC=2.4.1.1 779 0.0 B0K7V8.1 B0K7V8_THEP3 Phosphorylase EC=2.4.1.1 776 0.0 B0K6M7.1 B0K6M7_THEPX Phosphorylase EC=2.4.1.1 774 0.0 B7RA15.1 B7RA15_9THEO Phosphorylase EC=2.4.1.1 (Fragment) 757 0.0 Q97KR0.1 Q97KR0_CLOAB Phosphorylase EC=2.4.1.1 736 0.0 >Q8R925.1 Q8R925_THETN Phosphorylase EC=2.4.1.1 Length = 540 Score = 779 bits (2011), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/537 (68%), Positives = 439/537 (81%), Gaps = 3/537 (0%) Query: 4 KQLPSVAYFSMEYGLHSDFKMYAGGLGILAGDYIKGARDIQAPIIPIGLKWKQGYTDQKI 63 K+LP VAYF MEYGL S+FK+YAGGLGILAGDY+K A+++ P++ IG+ WKQGYT+Q I Sbjct: 4 KKLPRVAYFCMEYGLESNFKLYAGGLGILAGDYLKAAKEMGLPVVGIGILWKQGYTEQHI 63 Query: 64 DASGKPYDSYHNNV--YDFLEDTGVKVTVKVRKIDVVCKVWKTDHFGNSPLYLLDTDIPE 121 G PYD+Y N YDFL+DTGVKV VK+R DV CKVW D F N+PLYLLDTDIPE Sbjct: 64 GEDGYPYDAYRNYTRNYDFLKDTGVKVKVKIRNKDVYCKVWLVDSFDNAPLYLLDTDIPE 123 Query: 122 NGDAWITGQLYGWFGEERIAQEIVLGIGGVKAMRALQIPIDVYHFNEGHAALAAIELIRE 181 NGD WITGQLYGWFGEER+AQEIVLGIGGV+A+RAL I +D+YHFNEGHA LA IELIRE Sbjct: 124 NGDRWITGQLYGWFGEERVAQEIVLGIGGVRALRALGIDVDIYHFNEGHAVLAGIELIRE 183 Query: 182 KMSG-GSSFEEAWKATREEVVFTTHTPIKEGNETHPLDRLEYMGAFNGLTRDQMERIGGD 240 KM G SFEEAW+ATR+E+VFTTHTP+KEGNE+H L+ L YMGA NGLT +Q+ +IGG Sbjct: 184 KMENQGMSFEEAWEATRKEIVFTTHTPVKEGNESHDLELLMYMGANNGLTIEQLAQIGGV 243 Query: 241 PFNMTVAGLRLSRISNAVAQLHADTANKMWKEVAGRSEIIGITNAIHTPTWVDERMTRAF 300 PFNMTVAGLRLS+I+N V++LH TANKMW+ + ++ II ITN IH TWVD+R+T A+ Sbjct: 244 PFNMTVAGLRLSKIANGVSKLHGQTANKMWQHIENKAPIISITNGIHRGTWVDKRITEAY 303 Query: 301 EEGGDLWATHKEIKGELISFIEERSGISLNADNLLIGFSRRAAPYKRSDLIFSQPEIIEP 360 ++G L TH +K ELI F+ +++G+ L+AD LLIGFSRRAAPYKRSDLIF+ + I Sbjct: 304 KKGTGLLETHNLLKKELIDFVYKKTGVKLDADKLLIGFSRRAAPYKRSDLIFTNEKAIGE 363 Query: 361 YLESGRIQIVFSGKAHPLDDTGKKIVSNLVAMMKKYPKSVVFLENYDMTIGAMLTRGSDI 420 YL +IQIVFSGK HPLDD GK+IV+ +V M KKYP+SVVFLE+YDMTIG MLTRG+D+ Sbjct: 364 YLRDRKIQIVFSGKGHPLDDVGKEIVARIVKMTKKYPESVVFLEDYDMTIGKMLTRGADV 423 Query: 421 WLNNPRRPLEASGTSGMKAAMNGVLNCSILDGWWPEACIDGENGWQIGDGFETTDFAVLD 480 WLNNPRRPLEASGTSGMKAAMNGVLN SILDGWWPEACIDG NGWQ GDGFE+ +F LD Sbjct: 424 WLNNPRRPLEASGTSGMKAAMNGVLNLSILDGWWPEACIDGVNGWQFGDGFESDNFEELD 483 Query: 481 KHDSDALYDTLLKRVLPTFYKDKDKWVQMMHKSIETTRTEFASKRMLEEYYNRMYIK 537 KHD++ALYD LL +V+PT+Y DK KW +MM +SI TT F++ RML+EYY+ MY K Sbjct: 484 KHDAEALYDVLLNKVVPTYYNDKKKWEEMMKESIRTTFEAFSANRMLQEYYDLMYTK 540 >B0K7V8.1 B0K7V8_THEP3 Phosphorylase EC=2.4.1.1 Length = 541 Score = 776 bits (2004), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/539 (69%), Positives = 437/539 (81%), Gaps = 4/539 (0%) Query: 2 NEKQLPSVAYFSMEYGLHSDFKMYAGGLGILAGDYIKGARDIQAPIIPIGLKWKQGYTDQ 61 NEK LP VAYF MEYGL SDFK+YAGGLGILAGD++K A+++ P++ IG+ WKQGYT+Q Sbjct: 3 NEK-LPRVAYFCMEYGLQSDFKLYAGGLGILAGDHLKAAKELGMPLVGIGILWKQGYTEQ 61 Query: 62 KIDASGKPYDSYHNNV--YDFLEDTGVKVTVKVRKIDVVCKVWKTDHFGNSPLYLLDTDI 119 I G PYD+Y N YDFL+DTGVKV VK+R +V CKVW D+F N+PLYLLDTDI Sbjct: 62 HIGEDGYPYDAYRNYTRKYDFLKDTGVKVKVKIRNRNVYCKVWLIDNFDNAPLYLLDTDI 121 Query: 120 PENGDAWITGQLYGWFGEERIAQEIVLGIGGVKAMRALQIPIDVYHFNEGHAALAAIELI 179 PENGD WITGQLYGWFGEER+AQEIVLGIGGV+A+RAL I +DVYHFNEGHA LAAIELI Sbjct: 122 PENGDRWITGQLYGWFGEERVAQEIVLGIGGVRALRALGIDVDVYHFNEGHAVLAAIELI 181 Query: 180 REKMSGGS-SFEEAWKATREEVVFTTHTPIKEGNETHPLDRLEYMGAFNGLTRDQMERIG 238 REKM + SFEEAWKATREEVVFTTHTP+KEGNE+H L+ L YMGA NGL+ +QM +IG Sbjct: 182 REKMENQNMSFEEAWKATREEVVFTTHTPVKEGNESHDLELLMYMGANNGLSIEQMAQIG 241 Query: 239 GDPFNMTVAGLRLSRISNAVAQLHADTANKMWKEVAGRSEIIGITNAIHTPTWVDERMTR 298 G PFNMTVAGLRLSRI+N V++LH TANKMW+ V ++ II ITN I TWVD+R+ Sbjct: 242 GVPFNMTVAGLRLSRIANGVSKLHGQTANKMWQHVDNKAPIISITNGIDRNTWVDKRIIE 301 Query: 299 AFEEGGDLWATHKEIKGELISFIEERSGISLNADNLLIGFSRRAAPYKRSDLIFSQPEII 358 A+ +G L TH +K ELI F+ +R+G+ L+AD LLIGFSRRAAPYKRSDLIF+ E+I Sbjct: 302 AYNKGEGLLETHNILKQELIDFVYQRTGVKLDADKLLIGFSRRAAPYKRSDLIFTNDEVI 361 Query: 359 EPYLESGRIQIVFSGKAHPLDDTGKKIVSNLVAMMKKYPKSVVFLENYDMTIGAMLTRGS 418 YL S +IQ+VFSGK HPLDD GKKIV+ L+ M KKYP+SVVFLE+YDMTIG MLTRG+ Sbjct: 362 GDYLRSKKIQMVFSGKGHPLDDVGKKIVAKLIEMTKKYPESVVFLEDYDMTIGKMLTRGT 421 Query: 419 DIWLNNPRRPLEASGTSGMKAAMNGVLNCSILDGWWPEACIDGENGWQIGDGFETTDFAV 478 D+WLNNPRRPLEASGTSGMKAAMNGVLN SILDGWW EACIDG NGWQ GDGFE+ + Sbjct: 422 DVWLNNPRRPLEASGTSGMKAAMNGVLNLSILDGWWAEACIDGVNGWQFGDGFESDNIEE 481 Query: 479 LDKHDSDALYDTLLKRVLPTFYKDKDKWVQMMHKSIETTRTEFASKRMLEEYYNRMYIK 537 LDKHD +ALYD LL +V+PT+Y DK KW MM +SI TT F++ RML+EYY+ MY K Sbjct: 482 LDKHDLEALYDVLLNKVVPTYYNDKAKWENMMRESIRTTYEAFSANRMLKEYYDLMYTK 540 >B0K6M7.1 B0K6M7_THEPX Phosphorylase EC=2.4.1.1 Length = 541 Score = 774 bits (1998), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/539 (68%), Positives = 438/539 (81%), Gaps = 4/539 (0%) Query: 2 NEKQLPSVAYFSMEYGLHSDFKMYAGGLGILAGDYIKGARDIQAPIIPIGLKWKQGYTDQ 61 NEK LP VAYF MEYGL SDFK+YAGGLGILAGD++K A+++ P++ IG+ WKQGYT+Q Sbjct: 3 NEK-LPRVAYFCMEYGLQSDFKLYAGGLGILAGDHLKAAKELGMPLVGIGILWKQGYTEQ 61 Query: 62 KIDASGKPYDSYHNNV--YDFLEDTGVKVTVKVRKIDVVCKVWKTDHFGNSPLYLLDTDI 119 I G PYD+Y N YDFL+DTGVKV VK+R +V CKVW D+F N+PLYLLDTDI Sbjct: 62 HIGEDGYPYDAYRNYTRKYDFLKDTGVKVKVKIRNRNVYCKVWLIDNFDNAPLYLLDTDI 121 Query: 120 PENGDAWITGQLYGWFGEERIAQEIVLGIGGVKAMRALQIPIDVYHFNEGHAALAAIELI 179 PENGD WITGQLYGWFGEER+AQEIVLGIGGV+A+RAL I +DVYHFNEGHA LAAIELI Sbjct: 122 PENGDRWITGQLYGWFGEERVAQEIVLGIGGVRALRALGIDVDVYHFNEGHAVLAAIELI 181 Query: 180 REKMSGGS-SFEEAWKATREEVVFTTHTPIKEGNETHPLDRLEYMGAFNGLTRDQMERIG 238 +EKM + SFEEAWKATREEVVFTTHTP+KEGNE+H L+ L YMGA NGL+ +QM +IG Sbjct: 182 KEKMENQNMSFEEAWKATREEVVFTTHTPVKEGNESHDLELLMYMGANNGLSIEQMAQIG 241 Query: 239 GDPFNMTVAGLRLSRISNAVAQLHADTANKMWKEVAGRSEIIGITNAIHTPTWVDERMTR 298 G PFNMTVAGLRLSRI+N V++LH TAN+MW+ V ++ II ITN I TWVD+R+ Sbjct: 242 GVPFNMTVAGLRLSRIANGVSKLHGQTANRMWQHVDNKAPIISITNGIDRNTWVDKRIIE 301 Query: 299 AFEEGGDLWATHKEIKGELISFIEERSGISLNADNLLIGFSRRAAPYKRSDLIFSQPEII 358 A+ +G L TH +K ELI F+ +++G+ L+AD LLIGFSRRAAPYKRSDLIF+ E+I Sbjct: 302 AYNKGEGLLQTHNILKQELIDFVYQKTGVKLDADKLLIGFSRRAAPYKRSDLIFTNDEVI 361 Query: 359 EPYLESGRIQIVFSGKAHPLDDTGKKIVSNLVAMMKKYPKSVVFLENYDMTIGAMLTRGS 418 YL S +IQ+VFSGK HPLDD GKKIV+ L+ M KKYP+SVVFLE+YDMTIG MLTRG+ Sbjct: 362 GDYLRSKKIQMVFSGKGHPLDDVGKKIVAKLIEMTKKYPESVVFLEDYDMTIGKMLTRGT 421 Query: 419 DIWLNNPRRPLEASGTSGMKAAMNGVLNCSILDGWWPEACIDGENGWQIGDGFETTDFAV 478 D+WLNNPRRPLEASGTSGMKAAMNGVLN SILDGWWPEACI+G NGWQ GDGFE+ + Sbjct: 422 DVWLNNPRRPLEASGTSGMKAAMNGVLNLSILDGWWPEACINGVNGWQFGDGFESDNIEE 481 Query: 479 LDKHDSDALYDTLLKRVLPTFYKDKDKWVQMMHKSIETTRTEFASKRMLEEYYNRMYIK 537 LDKHD +ALYD LL +V+PT+Y DK KW MM +SI TT F++ RML+EYY+ MY K Sbjct: 482 LDKHDLEALYDVLLNKVVPTYYNDKAKWENMMRESIRTTYEAFSANRMLKEYYDLMYTK 540 >B7RA15.1 B7RA15_9THEO Phosphorylase EC=2.4.1.1 (Fragment) Length = 524 Score = 757 bits (1954), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/524 (68%), Positives = 428/524 (81%), Gaps = 3/524 (0%) Query: 17 GLHSDFKMYAGGLGILAGDYIKGARDIQAPIIPIGLKWKQGYTDQKIDASGKPYDSYHNN 76 GL S+FK+YAGGLGILAGDY+K A+++ P++ IG+ WKQGYT+Q I G PYD+Y N Sbjct: 1 GLESNFKLYAGGLGILAGDYLKAAKEMGLPVVGIGILWKQGYTEQHIGEDGYPYDAYRNY 60 Query: 77 V--YDFLEDTGVKVTVKVRKIDVVCKVWKTDHFGNSPLYLLDTDIPENGDAWITGQLYGW 134 YDFL+DTGVKV VK+R DV CKVW D F N+PLYLLDTDIPENGD WITGQLYGW Sbjct: 61 TRNYDFLKDTGVKVKVKIRNKDVYCKVWLVDSFDNAPLYLLDTDIPENGDRWITGQLYGW 120 Query: 135 FGEERIAQEIVLGIGGVKAMRALQIPIDVYHFNEGHAALAAIELIREKMSG-GSSFEEAW 193 FGEER+AQEIVLGIGGV+A+RAL I +D+YHFNEGHA LA IELIREKM G SFEEAW Sbjct: 121 FGEERVAQEIVLGIGGVRALRALGIDVDIYHFNEGHAVLAGIELIREKMENQGMSFEEAW 180 Query: 194 KATREEVVFTTHTPIKEGNETHPLDRLEYMGAFNGLTRDQMERIGGDPFNMTVAGLRLSR 253 +ATR+E+VFTTHTP+KEGNE+H L+ L YMGA NGLT +Q+ +IGG PFNMTVAGLRLS+ Sbjct: 181 EATRKEIVFTTHTPVKEGNESHDLELLMYMGANNGLTIEQLAQIGGVPFNMTVAGLRLSK 240 Query: 254 ISNAVAQLHADTANKMWKEVAGRSEIIGITNAIHTPTWVDERMTRAFEEGGDLWATHKEI 313 I+N V++LH TANKMW+ + ++ II ITN IH TWVD+R+T A+++G L TH + Sbjct: 241 IANGVSKLHGQTANKMWQHIENKAPIISITNGIHRGTWVDKRITEAYKKGTGLLETHNLL 300 Query: 314 KGELISFIEERSGISLNADNLLIGFSRRAAPYKRSDLIFSQPEIIEPYLESGRIQIVFSG 373 K ELI F+ +++G+ L+AD LLIGFSRRAAPYKRSDLIF+ + I YL +IQIVFSG Sbjct: 301 KKELIDFVYKKTGVKLDADKLLIGFSRRAAPYKRSDLIFTNEKAIGEYLRDRKIQIVFSG 360 Query: 374 KAHPLDDTGKKIVSNLVAMMKKYPKSVVFLENYDMTIGAMLTRGSDIWLNNPRRPLEASG 433 K HPLDD GK+IV+ +V M KKYP+SVVFLE+YDMTIG MLTRG+D+WLNNPRRPLEASG Sbjct: 361 KGHPLDDVGKEIVARIVKMTKKYPESVVFLEDYDMTIGKMLTRGADVWLNNPRRPLEASG 420 Query: 434 TSGMKAAMNGVLNCSILDGWWPEACIDGENGWQIGDGFETTDFAVLDKHDSDALYDTLLK 493 TSGMKAAMNGVLN SILDGWWPEACIDG NGWQ GDGFE+ +F LDKHD++ALYD LL Sbjct: 421 TSGMKAAMNGVLNLSILDGWWPEACIDGVNGWQFGDGFESDNFEELDKHDAEALYDVLLN 480 Query: 494 RVLPTFYKDKDKWVQMMHKSIETTRTEFASKRMLEEYYNRMYIK 537 +V+PT+Y DK KW +MM +SI TT F++ RML+EYY+ MY K Sbjct: 481 KVVPTYYNDKKKWEEMMKESIRTTFEAFSANRMLQEYYDLMYTK 524 >Q97KR0.1 Q97KR0_CLOAB Phosphorylase EC=2.4.1.1 Length = 540 Score = 736 bits (1900), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/534 (64%), Positives = 423/534 (79%), Gaps = 2/534 (0%) Query: 6 LPSVAYFSMEYGLHSDFKMYAGGLGILAGDYIKGARDIQAPIIPIGLKWKQGYTDQKIDA 65 LP +AYFSMEY + + K YAGGLGILAGDY+KG++D PII IG+KWKQGYTDQ ID Sbjct: 7 LPRIAYFSMEYAIDASIKTYAGGLGILAGDYLKGSKDYNYPIIGIGIKWKQGYTDQLIDE 66 Query: 66 SGKPYDSYHNNVYDFLEDTGVKVTVKVRKIDVVCKVWKTDHFGNSPLYLLDTDIPENGDA 125 + YD+YHN YDFL+DT +KV VK+ + DV CK+W D F +PLYLLDTD+PEN + Sbjct: 67 NSNVYDTYHNYKYDFLKDTKLKVKVKIYEKDVTCKIWLLDKFKLAPLYLLDTDLPENDNR 126 Query: 126 WITGQLYGWFGEERIAQEIVLGIGGVKAMRALQIPIDVYHFNEGHAALAAIELIREKMSG 185 WIT QLYG F + R+AQEIVLGIGGV+A+RAL I +DVYHFNEGHA A EL+REKM+ Sbjct: 127 WITNQLYGGFEDSRLAQEIVLGIGGVRALRALDINVDVYHFNEGHALFAGFELVREKMNT 186 Query: 186 GSSFEEAWKATREEVVFTTHTPIKEGNETHPLDRLEYMGAFNGLTRDQMERIGGDPFNMT 245 G F+EA K ++EE+VFTTHTPI EGNE+H + R+ +GA NG T +Q+ +GG PFNMT Sbjct: 187 GIPFDEAVKKSKEEIVFTTHTPIIEGNESHSISRMISIGANNGFTIEQLISLGGCPFNMT 246 Query: 246 VAGLRLSRISNAVAQLHADTANKMWKEVAGRSEIIGITNAIHTPTWVDERMTRAFEE--G 303 V LRLSRISNAV++LH +TANKMWK + +S+II ITNAIH PTWVDE M +A E+ Sbjct: 247 VGALRLSRISNAVSKLHGETANKMWKNIKNKSKIISITNAIHIPTWVDEDMLKAAEDSNS 306 Query: 304 GDLWATHKEIKGELISFIEERSGISLNADNLLIGFSRRAAPYKRSDLIFSQPEIIEPYLE 363 +LW H + K +LISF++ER+ I LN ++LLIGFSRRAAPYKRS+LIFS +II P L+ Sbjct: 307 NNLWTNHIKNKRKLISFVKERNEIELNENSLLIGFSRRAAPYKRSNLIFSDMKIISPLLK 366 Query: 364 SGRIQIVFSGKAHPLDDTGKKIVSNLVAMMKKYPKSVVFLENYDMTIGAMLTRGSDIWLN 423 G+IQIVFSGKAHPLDDTGK I+ NLV K+YP SVVFLENYDMTIG +LT+GSD+WLN Sbjct: 367 DGKIQIVFSGKAHPLDDTGKDIIKNLVNFSKQYPSSVVFLENYDMTIGKLLTQGSDVWLN 426 Query: 424 NPRRPLEASGTSGMKAAMNGVLNCSILDGWWPEACIDGENGWQIGDGFETTDFAVLDKHD 483 NPRRPLEASGTSGMKAAMNGVLN S LDGWWPEAC DG NGWQ GDG ++ D +DKHD Sbjct: 427 NPRRPLEASGTSGMKAAMNGVLNLSTLDGWWPEACRDGINGWQFGDGLQSDDIYFIDKHD 486 Query: 484 SDALYDTLLKRVLPTFYKDKDKWVQMMHKSIETTRTEFASKRMLEEYYNRMYIK 537 ++ALY+ L+ +V+PTFY ++ KW+ MM SI +T+ F+ KRMLEEYY+++YIK Sbjct: 487 ANALYEVLMNKVIPTFYLERKKWISMMKNSILSTKDYFSVKRMLEEYYSKIYIK 540 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,494,460,856 Number of extensions: 157020038 Number of successful extensions: 342600 Number of sequences better than 1.0e-05: 517 Number of HSP's gapped: 340661 Number of HSP's successfully gapped: 540 Length of query: 538 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 397 Effective length of database: 1,732,333,088 Effective search space: 687736235936 Effective search space used: 687736235936 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)