BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0057.0014.p (254 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q65M66.1 AROD_BACLD 3-dehydroquinate dehydratase EC=4.2.1.10 310 8e-83 Q92EG6.1 AROD_LISIN 3-dehydroquinate dehydratase EC=4.2.1.10 304 4e-81 Q723F8.1 AROD_LISMF 3-dehydroquinate dehydratase EC=4.2.1.10 304 6e-81 B8DCI1.1 AROD_LISMH 3-dehydroquinate dehydratase EC=4.2.1.10 304 6e-81 C4ILX8.1 C4ILX8_CLOBU 3-dehydroquinate dehydratase, type I EC=4.... 304 6e-81 >Q65M66.1 AROD_BACLD 3-dehydroquinate dehydratase EC=4.2.1.10 Length = 254 Score = 310 bits (794), Expect = 8e-83, Method: Compositional matrix adjust. Identities = 150/254 (59%), Positives = 184/254 (72%) Query: 1 MSGTVTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLA 60 M V V+ +TLGEG PKICV L+ + L D+ EWR+DF+ +V+D+ Sbjct: 1 MKKLVKVRGITLGEGRPKICVPLVGKNLAQLKEEAAYFQTLDADIAEWRADFYEDVDDVD 60 Query: 61 AVRKTLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFN 120 V LAEI +L DTPLIFTFRSA EGGE+EI+T Y LN+A ++G D+ID+ELFN Sbjct: 61 QVCAALAEIRGLLKDTPLIFTFRSAAEGGEKEISTARYFSLNEAVVKTGLADVIDIELFN 120 Query: 121 EENVVRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAG 180 +E V+ LV AH V VI+SNHDF TP+ EEIVSRLR+AQ LG DLPKIAVMP+ Sbjct: 121 DEEQVKALVETAHGHEVSVIISNHDFEKTPAAEEIVSRLRKAQELGADLPKIAVMPETTA 180 Query: 181 DVLTLLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAV 240 DVL LL AT TM E+YADRPIITMSMAG+G+ISRLAGE+FGSA+TFGAA K SAPGQ+A Sbjct: 181 DVLRLLEATCTMNEKYADRPIITMSMAGKGIISRLAGEVFGSAMTFGAAKKASAPGQIAA 240 Query: 241 AELRRVLELLHRSL 254 EL+ +L +LHR+L Sbjct: 241 GELKEILHILHRNL 254 >Q92EG6.1 AROD_LISIN 3-dehydroquinate dehydratase EC=4.2.1.10 Length = 252 Score = 304 bits (779), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 147/250 (58%), Positives = 185/250 (74%), Gaps = 1/250 (0%) Query: 5 VTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVRK 64 V VKNVT GEG PKICV ++ K + D+VEWR DFF +V+DL V+ Sbjct: 4 VVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLKTIDLDVVEWRVDFFEDVKDLVKVKA 63 Query: 65 TLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEENV 124 L EI ++LP+TP++FTFRSA+EGGE ++ E+Y LN+ A +G +D++DVELFNEE Sbjct: 64 ALDEIRAILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEAD 123 Query: 125 VRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVLT 184 V L+ AH V V++SNHDF TP++EEIVSRL + +ALG DLPKIAVMP+ AGDVLT Sbjct: 124 VLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGDVLT 183 Query: 185 LLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAELR 244 LL ATNT+ E+ A++PIITMSMAG GVISRLAGE+FGSA+TFGAA K SAPGQ+ V ELR Sbjct: 184 LLDATNTVSEK-ANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELR 242 Query: 245 RVLELLHRSL 254 VL+LLH+ Sbjct: 243 HVLDLLHKQF 252 >Q723F8.1 AROD_LISMF 3-dehydroquinate dehydratase EC=4.2.1.10 Length = 252 Score = 304 bits (778), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 147/250 (58%), Positives = 184/250 (73%), Gaps = 1/250 (0%) Query: 5 VTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVRK 64 V VKNVT GEG PKICV ++ + + D+VEWR DFF +V+DLA V Sbjct: 4 VVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEA 63 Query: 65 TLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEENV 124 L EI ++LP+TP++FTFRSA+EGGE + E+Y LN+ A +G +D++DVELFNEE Sbjct: 64 ALDEIRTILPETPILFTFRSAKEGGELAVGDEFYFELNETLASTGKIDLVDVELFNEETD 123 Query: 125 VRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVLT 184 V L+ AH V V++SNHDF TP++EEIVSRL + +ALG DLPKIAVMP+ AGDVLT Sbjct: 124 VLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGDVLT 183 Query: 185 LLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAELR 244 LL ATNT+ E+ A++PIITMSMAG GVISRLAGE+FGSA+TFGAA K SAPGQ+ V ELR Sbjct: 184 LLDATNTVSEK-ANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELR 242 Query: 245 RVLELLHRSL 254 VL+LLH+ Sbjct: 243 HVLDLLHKQF 252 >B8DCI1.1 AROD_LISMH 3-dehydroquinate dehydratase EC=4.2.1.10 Length = 252 Score = 304 bits (778), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 148/250 (59%), Positives = 185/250 (74%), Gaps = 1/250 (0%) Query: 5 VTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLAAVRK 64 V VKNVT GEG PKICV ++ + + D+VEWR DFF +V+DLA V Sbjct: 4 VVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEA 63 Query: 65 TLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFNEENV 124 L EI ++LP+TP++FTFRSA+EGGE ++ E+Y LN+ A +G VD++DVELFNEE Sbjct: 64 ALDEIRTILPETPILFTFRSAKEGGELAVSDEFYFELNETLARTGKVDLVDVELFNEEAD 123 Query: 125 VRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAGDVLT 184 V L+ AH V V++SNHDF TP++EEIVSRL + +ALG DLPKIAVMP+ AGDVLT Sbjct: 124 VLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLIRMEALGADLPKIAVMPKSAGDVLT 183 Query: 185 LLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAVAELR 244 LL ATNT+ E+ A++PIITMSMAG GVISRLAGE+FGSA+TFGAA K SAPGQ+ V ELR Sbjct: 184 LLDATNTVSEK-ANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELR 242 Query: 245 RVLELLHRSL 254 VL+LLH+ Sbjct: 243 HVLDLLHKQF 252 >C4ILX8.1 C4ILX8_CLOBU 3-dehydroquinate dehydratase, type I EC=4.2.1.10 Length = 254 Score = 304 bits (778), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 145/254 (57%), Positives = 184/254 (72%) Query: 1 MSGTVTVKNVTLGEGIPKICVSLISXXXXXXXXXXXXXKELAPDLVEWRSDFFAEVEDLA 60 MS V V+NV +GEGIPKI V ++ K + D+VEWR DF+ VED+ Sbjct: 1 MSNIVEVRNVKIGEGIPKITVPVVGTNNVELIEEVKGLKGIKLDIVEWRVDFYENVEDIE 60 Query: 61 AVRKTLAEISSVLPDTPLIFTFRSAREGGEREITTEYYIRLNQAAAESGYVDIIDVELFN 120 V++ L E+ VL DTP++FTFR+ +EGGERE+ EYY++LN A++ VD++DVELF Sbjct: 61 KVKEILGEMRKVLADTPILFTFRTKKEGGEREVPVEYYVKLNCEIAKTKQVDLVDVELFT 120 Query: 121 EENVVRELVAAAHACGVFVIVSNHDFHGTPSQEEIVSRLRQAQALGGDLPKIAVMPQQAG 180 +N V E+V AHA GV V++SNHDF TP++EEIVSRL + L DLPKIAVMPQ Sbjct: 121 GDNYVSEVVETAHANGVKVVMSNHDFFKTPAKEEIVSRLTKMTELKADLPKIAVMPQSEA 180 Query: 181 DVLTLLAATNTMREQYADRPIITMSMAGEGVISRLAGEIFGSALTFGAAHKPSAPGQVAV 240 DVLTLL ATN M+++YAD+PIITMSMAG GVISRLAGE FGS LTFGAA K SAPGQ+AV Sbjct: 181 DVLTLLCATNEMKQKYADQPIITMSMAGMGVISRLAGECFGSVLTFGAAKKASAPGQIAV 240 Query: 241 AELRRVLELLHRSL 254 +L VL++LH+S+ Sbjct: 241 EDLNTVLQILHKSI 254 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,344,424,558 Number of extensions: 50170662 Number of successful extensions: 139241 Number of sequences better than 1.0e-05: 448 Number of HSP's gapped: 138797 Number of HSP's successfully gapped: 448 Length of query: 254 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 121 Effective length of database: 1,807,701,208 Effective search space: 218731846168 Effective search space used: 218731846168 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)