BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0056.0002.p (431 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2YQ33.1 C2YQ33_BACCE Tetracycline resistance determinant tetV 443 e-122 C2W6L5.1 C2W6L5_BACCE Tetracycline resistance determinant tetV 442 e-122 C3BIU7.1 C3BIU7_9BACI Tetracycline resistance determinant tetV 438 e-121 C3B245.1 C3B245_BACMY Tetracycline resistance determinant tetV 437 e-121 C3AK81.1 C3AK81_BACMY Tetracycline resistance determinant tetV 437 e-121 >C2YQ33.1 C2YQ33_BACCE Tetracycline resistance determinant tetV Length = 420 Score = 443 bits (1139), Expect = e-122, Method: Compositional matrix adjust. Identities = 220/411 (53%), Positives = 280/411 (68%), Gaps = 10/411 (2%) Query: 21 PFAKSRAFPFLWLGHLISFLGSSVTMVILPVLVYSLTGSTTTMGVVMAVYMLPNILMLPV 80 P S F FLW+G L+S LGSS+TMVILPV+VYSLTGST MG+ MA+YMLPNIL LP Sbjct: 20 PVKVSPHFKFLWIGQLLSTLGSSITMVILPVVVYSLTGSTVVMGMTMAMYMLPNILALPF 79 Query: 81 SGHIVDRYDRVGIMMLADIFRALIMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFQPAY 140 +G +VDR DRV +M+ DI R ++M FQPAY Sbjct: 80 AGLVVDRIDRVKLMLFTDIIRCVLMLLLATLIFMDVLTIPLLYVLVALYGLMEGIFQPAY 139 Query: 141 AAVRATVFTPDIRVTANSVTQITTQTVRLIGPALGGLLITHLSAGIGFGLDAFTYVFSFI 200 AAVRA VF P+IR AN++TQ++ Q +RLIGPALGGL+++ SAGIGFGLDA TY+ SF+ Sbjct: 140 AAVRAKVFVPEIRNAANALTQMSNQGIRLIGPALGGLIVSVASAGIGFGLDAVTYLLSFL 199 Query: 201 CLIYLRRALIARVRTDASGTAGSMAAPSPSADWKQDFMEGLAVLRSHPWLWITILAFSFI 260 CLI+LR +V D+KQ+FMEG+ VL+SHPWLWITIL FSFI Sbjct: 200 CLIFLREIKFKKVN----------PIEKRKVDYKQEFMEGVFVLKSHPWLWITILVFSFI 249 Query: 261 NICYGGITSILVPWLFKVQHGWDPYLYGLAVTCSXXXXXXXXXXFGTRQRWSRRGLMAYG 320 NICY GI +L+PWLF V H ++ Y+YGL + S FG R+RW +RGL+AYG Sbjct: 250 NICYAGIIVVLIPWLFNVHHHFEAYVYGLGMASSGVGAVIAALIFGGRERWHKRGLLAYG 309 Query: 321 GAFISGVSLLLLPFVPSAAGAVILFSLEGFGLMVFMLIWEISMQELVPQEAFGRVASLDL 380 G ISG +LL++PF+ SA G ++L ++EGFG+M+F LIWE S+QELVP+EAFGRVASLD+ Sbjct: 310 GVLISGCALLIMPFIASAPGLIVLMAIEGFGMMIFGLIWETSLQELVPEEAFGRVASLDM 369 Query: 381 LGSFALLPVGYILVGWLADLIGGVATIAIFSGLGMACIALVLSIPAIRNFQ 431 LGSFALLP+GY++VGWLA +IGG TI + L + I + L +P+IR F Sbjct: 370 LGSFALLPLGYVVVGWLATVIGGEITIITLAILVLVTIGVALCVPSIRRFD 420 >C2W6L5.1 C2W6L5_BACCE Tetracycline resistance determinant tetV Length = 420 Score = 442 bits (1138), Expect = e-122, Method: Compositional matrix adjust. Identities = 224/430 (52%), Positives = 287/430 (66%), Gaps = 10/430 (2%) Query: 2 MPASTSESGKTNPFRGFAAPFAKSRAFPFLWLGHLISFLGSSVTMVILPVLVYSLTGSTT 61 M K N P KSR F FLW+G L+S LGSS+TMVILPV+VY+LTGST Sbjct: 1 MQGEVQTENKGNYVSNLLLPVTKSRHFTFLWIGQLLSVLGSSITMVILPVVVYTLTGSTV 60 Query: 62 TMGVVMAVYMLPNILMLPVSGHIVDRYDRVGIMMLADIFRALIMXXXXXXXXXXXXXXXX 121 MG MA+YMLPNIL+LP SG IVDR +RV M+ D+ R ++M Sbjct: 61 VMGTTMAMYMLPNILVLPFSGLIVDRINRVKFMLFTDVVRCILMITLAVLMFTNTLTITI 120 Query: 122 XXXXXXXXXXXXXXFQPAYAAVRATVFTPDIRVTANSVTQITTQTVRLIGPALGGLLITH 181 FQPAYAAVRA VF P+IR AN++TQ++ Q VRLIGPALGGL+++ Sbjct: 121 LYVLVAIYGLMEGLFQPAYAAVRARVFVPEIRNAANALTQMSNQGVRLIGPALGGLIVSV 180 Query: 182 LSAGIGFGLDAFTYVFSFICLIYLRRALIARVRTDASGTAGSMAAPSPSADWKQDFMEGL 241 SAGIGFGLDA TY+ SF+CL++L+ +V+ + ++K+DF EG+ Sbjct: 181 ASAGIGFGLDALTYLLSFVCLLFLKDVTAKKVQEQTN----------QKMNFKKDFTEGI 230 Query: 242 AVLRSHPWLWITILAFSFINICYGGITSILVPWLFKVQHGWDPYLYGLAVTCSXXXXXXX 301 VL+SHPWLWITILAFSFINICY GI +L+PWLF + H ++P++YGL + S Sbjct: 231 VVLKSHPWLWITILAFSFINICYAGIIVVLIPWLFHIHHQFEPFVYGLGMAFSGAGAVVA 290 Query: 302 XXXFGTRQRWSRRGLMAYGGAFISGVSLLLLPFVPSAAGAVILFSLEGFGLMVFMLIWEI 361 FG +QRW +RGL+AYGG ISG+SLLL+PFV A G + L +LEGFG+M+F LIWE Sbjct: 291 ALIFGGKQRWHKRGLLAYGGVLISGISLLLMPFVSWAPGLIGLMALEGFGIMIFGLIWET 350 Query: 362 SMQELVPQEAFGRVASLDLLGSFALLPVGYILVGWLADLIGGVATIAIFSGLGMACIALV 421 S+QELVP+EAFGRVASLD+LGSFALLP+GYI+VGWLA++IGG TI I + + + + Sbjct: 351 SLQELVPEEAFGRVASLDMLGSFALLPLGYIVVGWLANVIGGTVTITILAIAAIIVVVIA 410 Query: 422 LSIPAIRNFQ 431 L +P+IR F Sbjct: 411 LFVPSIRQFD 420 >C3BIU7.1 C3BIU7_9BACI Tetracycline resistance determinant tetV Length = 420 Score = 438 bits (1126), Expect = e-121, Method: Compositional matrix adjust. Identities = 228/430 (53%), Positives = 290/430 (67%), Gaps = 10/430 (2%) Query: 2 MPASTSESGKTNPFRGFAAPFAKSRAFPFLWLGHLISFLGSSVTMVILPVLVYSLTGSTT 61 M K + P KSR F FLW+G L+S LGSSVTMVILPV+VY+LTGST Sbjct: 1 MQGEIQTKNKGSYVSNLLLPVTKSRQFTFLWIGQLLSVLGSSVTMVILPVVVYTLTGSTV 60 Query: 62 TMGVVMAVYMLPNILMLPVSGHIVDRYDRVGIMMLADIFRALIMXXXXXXXXXXXXXXXX 121 MG+ MA+YMLPNIL+LP SG IVDR +RV +M+ DI R ++M Sbjct: 61 VMGMTMAMYMLPNILVLPFSGLIVDRMNRVKLMLFTDIVRCIVMITLATLIFTDTLTINI 120 Query: 122 XXXXXXXXXXXXXXFQPAYAAVRATVFTPDIRVTANSVTQITTQTVRLIGPALGGLLITH 181 FQPAYAAVRA VF P+IR AN++TQ++ Q VRLIGPALGGL+++ Sbjct: 121 LYVLVAVYGLMEGLFQPAYAAVRARVFVPEIRNAANALTQMSNQGVRLIGPALGGLIVSV 180 Query: 182 LSAGIGFGLDAFTYVFSFICLIYLRRALIARVRTDASGTAGSMAAPSPSADWKQDFMEGL 241 SAGIGFGLDA TY+ SFICL++L+ +V+ + + K+DF EG+ Sbjct: 181 ASAGIGFGLDALTYLLSFICLLFLKDVTAKKVQEQTN----------QKMNLKKDFTEGI 230 Query: 242 AVLRSHPWLWITILAFSFINICYGGITSILVPWLFKVQHGWDPYLYGLAVTCSXXXXXXX 301 VL+SHPWLWITILAFSFINICY GI +L+PWLF + H ++P++YGL + CS Sbjct: 231 VVLKSHPWLWITILAFSFINICYAGIIVVLIPWLFNIHHQFEPFVYGLGMACSGAGAVVA 290 Query: 302 XXXFGTRQRWSRRGLMAYGGAFISGVSLLLLPFVPSAAGAVILFSLEGFGLMVFMLIWEI 361 FG RQRW +RGL+AYGG ISG+SLLL+PFV A G + L +LEGFG+M+F LIWE Sbjct: 291 ALIFGGRQRWHKRGLLAYGGVLISGMSLLLMPFVSWAPGLIGLMALEGFGIMIFGLIWET 350 Query: 362 SMQELVPQEAFGRVASLDLLGSFALLPVGYILVGWLADLIGGVATIAIFSGLGMACIALV 421 S+QELVP+EAFGRVASLD+LGSFALLP+GY++VGWLA++IGG TI I + + +A+ Sbjct: 351 SLQELVPEEAFGRVASLDMLGSFALLPLGYLVVGWLANIIGGTVTIIILAIAAIVVVAIA 410 Query: 422 LSIPAIRNFQ 431 L +P+IR F Sbjct: 411 LLVPSIRKFD 420 >C3B245.1 C3B245_BACMY Tetracycline resistance determinant tetV Length = 420 Score = 437 bits (1124), Expect = e-121, Method: Compositional matrix adjust. Identities = 228/430 (53%), Positives = 290/430 (67%), Gaps = 10/430 (2%) Query: 2 MPASTSESGKTNPFRGFAAPFAKSRAFPFLWLGHLISFLGSSVTMVILPVLVYSLTGSTT 61 M K + P KSR F FLW+G L+S LGSSVTMVILPV+VY+LTGST Sbjct: 1 MQGEIQAKNKGSYVSNLLLPVTKSRHFTFLWIGQLLSVLGSSVTMVILPVVVYTLTGSTV 60 Query: 62 TMGVVMAVYMLPNILMLPVSGHIVDRYDRVGIMMLADIFRALIMXXXXXXXXXXXXXXXX 121 MG+ MA+YMLPNIL+LP SG IVDR +RV +M+ DI R ++M Sbjct: 61 VMGMTMAMYMLPNILVLPFSGLIVDRMNRVKLMLFTDIVRCIVMITLATLIFTDTLTINI 120 Query: 122 XXXXXXXXXXXXXXFQPAYAAVRATVFTPDIRVTANSVTQITTQTVRLIGPALGGLLITH 181 FQPAYAAVRA VF P+IR AN++TQ++ Q VRLIGPALGGL+++ Sbjct: 121 LYVLVAVYGLMEGLFQPAYAAVRARVFVPEIRNAANALTQMSNQGVRLIGPALGGLIVSV 180 Query: 182 LSAGIGFGLDAFTYVFSFICLIYLRRALIARVRTDASGTAGSMAAPSPSADWKQDFMEGL 241 SAGIGFGLDA TY+ SFICL++L+ +V+ + + K+DF EG+ Sbjct: 181 ASAGIGFGLDALTYLLSFICLLFLKDVTAKKVQEQTN----------QKMNLKKDFTEGI 230 Query: 242 AVLRSHPWLWITILAFSFINICYGGITSILVPWLFKVQHGWDPYLYGLAVTCSXXXXXXX 301 VL+SHPWLWITILAFSFINICY GI +L+PWLF + H ++P++YGL + CS Sbjct: 231 VVLKSHPWLWITILAFSFINICYAGIIVVLIPWLFNIHHQFEPFVYGLGMACSGAGAVVA 290 Query: 302 XXXFGTRQRWSRRGLMAYGGAFISGVSLLLLPFVPSAAGAVILFSLEGFGLMVFMLIWEI 361 FG RQRW +RGL+AYGG ISG+SLLL+PFV A G + L +LEGFG+M+F LIWE Sbjct: 291 ALIFGGRQRWHKRGLLAYGGVLISGMSLLLMPFVSWAPGLIGLMALEGFGIMIFGLIWET 350 Query: 362 SMQELVPQEAFGRVASLDLLGSFALLPVGYILVGWLADLIGGVATIAIFSGLGMACIALV 421 S+QELVP+EAFGRVASLD+LGSFALLP+GY++VGWLA++IGG TI I + + +A+ Sbjct: 351 SLQELVPEEAFGRVASLDMLGSFALLPLGYLVVGWLANIIGGTVTIIILAIAAIVVVAIA 410 Query: 422 LSIPAIRNFQ 431 L +P+IR F Sbjct: 411 LLVPSIRKFD 420 >C3AK81.1 C3AK81_BACMY Tetracycline resistance determinant tetV Length = 420 Score = 437 bits (1124), Expect = e-121, Method: Compositional matrix adjust. Identities = 229/430 (53%), Positives = 291/430 (67%), Gaps = 10/430 (2%) Query: 2 MPASTSESGKTNPFRGFAAPFAKSRAFPFLWLGHLISFLGSSVTMVILPVLVYSLTGSTT 61 M K + P KSR F FLW+G L+S LGSSVTMVILPV+VY+LTGST Sbjct: 1 MQGEIQAKNKGSYVSNLLLPVTKSRHFTFLWIGQLLSVLGSSVTMVILPVVVYTLTGSTV 60 Query: 62 TMGVVMAVYMLPNILMLPVSGHIVDRYDRVGIMMLADIFRALIMXXXXXXXXXXXXXXXX 121 MG+ MA+YMLPNIL+LP SG IVDR +RV +M+ DI R ++M Sbjct: 61 VMGMTMAMYMLPNILVLPFSGLIVDRMNRVKLMLFTDIVRCIVMITLATLIFTDTLTINI 120 Query: 122 XXXXXXXXXXXXXXFQPAYAAVRATVFTPDIRVTANSVTQITTQTVRLIGPALGGLLITH 181 FQPAYAAVRA VF P+IR AN++TQ++ Q VRLIGPALGGL+++ Sbjct: 121 LYVLVAVYGLMEGLFQPAYAAVRARVFVPEIRNAANALTQMSNQGVRLIGPALGGLIVSV 180 Query: 182 LSAGIGFGLDAFTYVFSFICLIYLRRALIARVRTDASGTAGSMAAPSPSADWKQDFMEGL 241 SAGIGFGLDA TY+ SFICL++L+ +V+ + + K+DF EG+ Sbjct: 181 ASAGIGFGLDALTYLLSFICLLFLKDVTAKKVQEQTN----------QKMNLKKDFTEGI 230 Query: 242 AVLRSHPWLWITILAFSFINICYGGITSILVPWLFKVQHGWDPYLYGLAVTCSXXXXXXX 301 VL+SHPWLWITILAFSFINICY GI +L+PWLF + H ++P++YGL + CS Sbjct: 231 VVLKSHPWLWITILAFSFINICYAGIIVVLIPWLFNIHHQFEPFVYGLGMACSGAGAVVA 290 Query: 302 XXXFGTRQRWSRRGLMAYGGAFISGVSLLLLPFVPSAAGAVILFSLEGFGLMVFMLIWEI 361 FG RQRW +RGL+AYGG ISG+SLLL+PFV A G + L +LEGFG+M+F LIWE Sbjct: 291 ALIFGGRQRWHKRGLLAYGGVLISGMSLLLMPFVSWAPGLIGLMALEGFGIMIFGLIWET 350 Query: 362 SMQELVPQEAFGRVASLDLLGSFALLPVGYILVGWLADLIGGVATIAIFSGLGMACIALV 421 S+QELVP+EAFGRVASLD+LGSFALLP+GY++VGWLA++IGGV TI I + + +A+ Sbjct: 351 SLQELVPEEAFGRVASLDMLGSFALLPLGYLVVGWLANIIGGVVTIIILAIAAIVVVAIA 410 Query: 422 LSIPAIRNFQ 431 L +P+IR F Sbjct: 411 LLVPSIRKFD 420 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.329 0.142 0.443 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,252,274,814 Number of extensions: 87098430 Number of successful extensions: 369649 Number of sequences better than 1.0e-05: 1117 Number of HSP's gapped: 368479 Number of HSP's successfully gapped: 1120 Length of query: 431 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 292 Effective length of database: 1,751,175,118 Effective search space: 511343134456 Effective search space used: 511343134456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.8 bits) S2: 133 (55.8 bits)