BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0054.0011.p (269 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K854.1 B3K854_9BACI GCN5-related N-acetyltransferase 216 3e-54 B1DCX8.1 B1DCX8_9BACL GCN5-related N-acetyltransferase 215 3e-54 A6LXX8.1 A6LXX8_CLOB8 GCN5-related N-acetyltransferase 181 5e-44 Q8THK2.1 Q8THK2_METAC Acetyltransferase (GNAT) family protein 117 8e-25 Q2B8E4.1 Q2B8E4_9BACI Acetyltransferase, GNAT family protein 96 3e-18 >B3K854.1 B3K854_9BACI GCN5-related N-acetyltransferase Length = 272 Score = 216 bits (549), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 113/268 (42%), Positives = 151/268 (56%) Query: 1 MFVSFETGDMVLQSEAFMQEEVRYNLIHRITEYPEAIRLTTADRKLIFTQSQGHNPWLWV 60 M D L E F+++EV YNLIH I P+ I L + D ++I+ QS N WLW+ Sbjct: 1 MLTKLMPQDEALCREEFIRDEVSYNLIHLIAGSPQRIGLKSPDGRMIYAQSPRGNAWLWI 60 Query: 61 SGELHEGQQTKLVQLLAEWVRTYEFPGISAQPETAKTFAEAFCGGQGKLYHTHMMLEAYQ 120 S ++ ++ L++ L + PG++ +P A+ FA + + Y M +E+Y Sbjct: 61 SRDVTMDRRQFLLRELVSELGEAALPGVTGEPGVAEQFASCYAEERHGAYRHQMTMESYH 120 Query: 121 CLMVRKPAGVRGSLEQAKAEHVPVIAGFLAGFMKDAFGERLRAEDFLKIAAEDAASGNLY 180 V+ P GV G + +A E +A FL GF +DA+G R A ++ A G LY Sbjct: 121 APTVKSPLGVEGRIRRAAVEDTQKVARFLVGFSEDAYGVRANAASQVETAERLIQQGGLY 180 Query: 181 LWTEEHTPVSMAKITHRSARHARINDVYTPSVHRKQGYASALVAALCGRLLDEGLTPVLY 240 +W VSMA I HRS RH RIN VYTP RK+GYASALVA L LL EGL P+LY Sbjct: 181 VWMAGSHTVSMANIAHRSPRHGRINAVYTPKEERKKGYASALVADLGSILLQEGLVPMLY 240 Query: 241 ADGKNPDSNKVYQSIGFQHAGQIADLKF 268 AD NPDSN++YQ IGF G I+DLKF Sbjct: 241 ADQANPDSNRLYQHIGFTRCGTISDLKF 268 >B1DCX8.1 B1DCX8_9BACL GCN5-related N-acetyltransferase Length = 272 Score = 215 bits (548), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 115/257 (44%), Positives = 152/257 (59%), Gaps = 1/257 (0%) Query: 12 LQSEAFMQEEVRYNLIHRITEYPEAIRLTTADRKLIFTQSQGHNPWLWVSGELHEGQQTK 71 L+S F+ +EV+ NL+HRI E +++ A IF S GHN WLWV L E + Sbjct: 15 LRSPLFVTDEVKMNLLHRICEMSQSVIYRAAGGSAIFAGSPGHNAWLWVDEALPE-EARL 73 Query: 72 LVQLLAEWVRTYEFPGISAQPETAKTFAEAFCGGQGKLYHTHMMLEAYQCLMVRKPAGVR 131 L+ + + GI+A+P AK FAE + M +EAY C +R P+ V+ Sbjct: 74 LLLKALVRLTGHSLRGITAEPRHAKLFAELYAVRYRVRPEYKMGMEAYYCPDIRYPSAVK 133 Query: 132 GSLEQAKAEHVPVIAGFLAGFMKDAFGERLRAEDFLKIAAEDAASGNLYLWTEEHTPVSM 191 G L A P+IA F+AGF + A+G ++ L A A+GNLY+W + PVSM Sbjct: 134 GELRPTVASDAPLIADFMAGFAESAYGYKVHPASQLPTAENTIATGNLYIWIVDQMPVSM 193 Query: 192 AKITHRSARHARINDVYTPSVHRKQGYASALVAALCGRLLDEGLTPVLYADGKNPDSNKV 251 A I HRS HARIN VYTP RKQG+ASA VAA CG ++ E P+LYAD NPDSNKV Sbjct: 194 AHIAHRSPSHARINYVYTPLELRKQGFASATVAACCGLIVQENRIPMLYADLTNPDSNKV 253 Query: 252 YQSIGFQHAGQIADLKF 268 YQ+IGF +G++AD+KF Sbjct: 254 YQNIGFVESGKVADVKF 270 >A6LXX8.1 A6LXX8_CLOB8 GCN5-related N-acetyltransferase Length = 276 Score = 181 bits (460), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 90/270 (33%), Positives = 144/270 (53%), Gaps = 1/270 (0%) Query: 1 MFVSFETGDMVLQSEAFMQEEVRYNLIHRITEYPEAIRLTTADRKLIFTQSQGHNP-WLW 59 M + F+ D +L S+ F +EV++NL+H + E T +R +I QS P W+W Sbjct: 1 MLIRFQGNDSILDSKPFTDDEVQFNLLHLVRESESPYLFTNKNRSIIIGQSALKYPAWIW 60 Query: 60 VSGELHEGQQTKLVQLLAEWVRTYEFPGISAQPETAKTFAEAFCGGQGKLYHTHMMLEAY 119 + + +L E + A+P+ A AE + + K Y + +E++ Sbjct: 61 TDNNVTKNDIDELKNDFTELYKDVGMLTFVAKPDIAILLAEHYSKVKHKNYSISLQMESF 120 Query: 120 QCLMVRKPAGVRGSLEQAKAEHVPVIAGFLAGFMKDAFGERLRAEDFLKIAAEDAASGNL 179 QC V + ++G L QA + +I+ FL+GF+ D FG+ +E+ L+ A S NL Sbjct: 121 QCPSVIEAKQIKGHLRQATINDITIISEFLSGFVYDCFGKETTSEEHLQTAKMYIESKNL 180 Query: 180 YLWTEEHTPVSMAKITHRSARHARINDVYTPSVHRKQGYASALVAALCGRLLDEGLTPVL 239 Y+W + +SMA I HRS R+ RIN VYT R +G+ + +V+ LC +L E TPVL Sbjct: 181 YIWECDSKTISMASIAHRSQRNVRINGVYTIPDMRGKGFGAKIVSELCKIILSEHRTPVL 240 Query: 240 YADGKNPDSNKVYQSIGFQHAGQIADLKFD 269 Y D +NP SNK Y+++GF G++ + F+ Sbjct: 241 YTDLRNPASNKAYKNVGFTECGKVTQISFN 270 >Q8THK2.1 Q8THK2_METAC Acetyltransferase (GNAT) family protein Length = 276 Score = 117 bits (294), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 76/259 (29%), Positives = 121/259 (46%), Gaps = 14/259 (5%) Query: 19 QEEVRYNLIHRITEYPEAIRLTTADRKLIFTQSQGHNP-WLWVSGELHEGQQTKLVQLLA 77 ++ + YNL + I E A T D I Q P W+W+ E + ++ ++ Sbjct: 18 KDRIIYNLFYLIREGDSAF-FATDDSTYIIGQGNESAPLWMWLKQIPDENVENEICDIIK 76 Query: 78 EWVRTYEFPGISAQPETAKTFAEAFCGGQGKLYHTHMMLEAYQCLMVRKPAGVRGSLEQA 137 + ++ ++A + A+ + G Y + + AY C + G + Sbjct: 77 SRLVLNQYLQLNAYDKYARKILDRVSKKTGLGYCVSVPMIAYACNQAISRYKISGQIVTP 136 Query: 138 KAEHVPVIAGFLAGFM--------KDAFGERLRAEDFLKIAAEDAASGNLYLWTEEHTPV 189 K EH ++A F+ F+ K A E +A F A S NL+LW ++ V Sbjct: 137 KEEHKEIMARFITEFITEITYDTEKTAINES-KANGF---ANAMVNSNNLFLWEDDGKIV 192 Query: 190 SMAKITHRSARHARINDVYTPSVHRKQGYASALVAALCGRLLDEGLTPVLYADGKNPDSN 249 SMA+I H++ +ARIN V+T R +GYA LV + +LL+E P+LYAD +NP SN Sbjct: 193 SMARIAHKTGEYARINTVFTEREQRGKGYAGMLVGKMSEKLLEENRIPMLYADARNPASN 252 Query: 250 KVYQSIGFQHAGQIADLKF 268 YQ IGF G++ + F Sbjct: 253 AAYQKIGFVKYGEVTEYVF 271 >Q2B8E4.1 Q2B8E4_9BACI Acetyltransferase, GNAT family protein Length = 282 Score = 96.3 bits (238), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 70/211 (33%), Positives = 100/211 (47%), Gaps = 2/211 (0%) Query: 58 LWVSGELHEGQQTKLVQLLAEWVRTYEFPGISAQPETAKTFAEAFCGGQGKLYHTHMMLE 117 +W +G++ + +++ L E R FPGI A ETA+ + G T M Sbjct: 73 IWSAGDIPDEAAALVLRELFE--RNISFPGIVAPKETARKAEAEWKKLTGAGSETVMDQR 130 Query: 118 AYQCLMVRKPAGVRGSLEQAKAEHVPVIAGFLAGFMKDAFGERLRAEDFLKIAAEDAASG 177 Y V G+L A + + AG+++ F + L E+ K A + + Sbjct: 131 IYILEKVNDLPYAGGTLSLASEKDEELAAGWISDFSRATPENTLSIEEGRKKARQFISER 190 Query: 178 NLYLWTEEHTPVSMAKITHRSARHARINDVYTPSVHRKQGYASALVAALCGRLLDEGLTP 237 +LYLW ++ PVSMAK + +N VYTP RK+GYASA VAAL LL Sbjct: 191 SLYLWLKDGRPVSMAKKARPTKHGVVVNLVYTPDEERKKGYASACVAALSRELLKSYKFC 250 Query: 238 VLYADGKNPDSNKVYQSIGFQHAGQIADLKF 268 LY D NP SN +YQ IG++ A LK+ Sbjct: 251 SLYTDLANPTSNHIYQEIGYKPAADSVMLKW 281 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.134 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,623,906,102 Number of extensions: 64126499 Number of successful extensions: 201910 Number of sequences better than 1.0e-05: 116 Number of HSP's gapped: 201761 Number of HSP's successfully gapped: 116 Length of query: 269 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 136 Effective length of database: 1,807,701,208 Effective search space: 245847364288 Effective search space used: 245847364288 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)