BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0053.0004.p (324 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0K7P8.1 B0K7P8_THEP3 Transcriptional regulator, LacI family 398 e-109 B0K6E2.1 B0K6E2_THEPX Regulatory protein, LacI 396 e-108 B8DZA4.1 B8DZA4_DICTD Transcriptional regulator, LacI family 366 2e-99 B5YAX3.1 B5YAX3_DICT6 Transcriptional regulator 357 6e-97 Q8GM38.1 Q8GM38_BACME Repressor FruR 301 4e-80 >B0K7P8.1 B0K7P8_THEP3 Transcriptional regulator, LacI family Length = 324 Score = 398 bits (1022), Expect = e-109, Method: Compositional matrix adjust. Identities = 180/324 (55%), Positives = 251/324 (77%) Query: 1 MATINDVAEQAGVSVTTVSRVLNNRGYISEKTRQKVYQVMDELNYQPNELARSLLRKHSN 60 M TI DVA++AGV+VTTVSRVLNNRGYISE TR+KVY+ M ELNYQPNELARSL RK S Sbjct: 1 MPTIKDVAKKAGVTVTTVSRVLNNRGYISEVTRKKVYEAMKELNYQPNELARSLYRKKSY 60 Query: 61 VLGLIIPSVAHPFFGELANAIESVAYQHGFKLLLCNSQLDSAKEREYVDMMRRNRVDGMI 120 ++GL+IP+VAHPFF EL IE AYQ G+K+LLCNS DS+KE+EY+DM++R++VDG+I Sbjct: 61 LIGLLIPNVAHPFFAELTGYIEYYAYQEGYKILLCNSGQDSSKEKEYIDMLKRHQVDGII 120 Query: 121 LGSHTLEIGDYTHLNYPLVTIDRRIGDIPFVASDNENGGALAARLLIAKGCRKIGHLSGN 180 +GSHTLE Y ++ P+V IDR +IP+VASDN GG LA +LLI KGC+KI H+SG Sbjct: 121 IGSHTLEAEQYLNVKLPIVAIDRYYSNIPYVASDNYKGGILATKLLIQKGCKKIAHISGP 180 Query: 181 MKLDMLSNLRTTGFEREARQGGVKFVTYQTELDVFDEQIYNEIIRKMFTEHPDIDGVFAT 240 + L+ +N R F+ A Q V++ +T+L+ F+ + Y +I+R +F EHPDIDG+FA+ Sbjct: 181 LILNTPANNRYKAFKEVATQENVEYFVVETKLNRFEIEEYKKIVRGLFKEHPDIDGIFAS 240 Query: 241 SDLMALFVMKWCRTFGKEVPRDVRIIGYDDIDAASWYMPGLSTIKQPIKDMARRAVELLL 300 DL+A V+ + K++P+D++I+GYDDI+ A+ +P L+T++QPIK++AR+A+EL+L Sbjct: 241 GDLIAASVISVAKELNKKIPQDLKIVGYDDINVANLVVPSLTTVRQPIKEIARKAIELIL 300 Query: 301 EQMDDKTVERETVLPVELVEREST 324 Q+D + VE+E +LP+ L+ERE+T Sbjct: 301 RQIDGEKVEKENILPITLIERETT 324 >B0K6E2.1 B0K6E2_THEPX Regulatory protein, LacI Length = 324 Score = 396 bits (1017), Expect = e-108, Method: Compositional matrix adjust. Identities = 179/324 (55%), Positives = 251/324 (77%) Query: 1 MATINDVAEQAGVSVTTVSRVLNNRGYISEKTRQKVYQVMDELNYQPNELARSLLRKHSN 60 M TI DVA++AGV+VTTVSRVLNNRGYISE TR+KVY+ M ELNYQPNELARSL RK S Sbjct: 1 MPTIKDVAKKAGVTVTTVSRVLNNRGYISEVTRKKVYEAMKELNYQPNELARSLYRKKSY 60 Query: 61 VLGLIIPSVAHPFFGELANAIESVAYQHGFKLLLCNSQLDSAKEREYVDMMRRNRVDGMI 120 ++GL+IP+V+HPFF EL IE AYQ G+K+LLCNS DS+KE+ Y+DM++R++VDG+I Sbjct: 61 LIGLLIPNVSHPFFAELTGYIEYYAYQEGYKILLCNSGQDSSKEKGYIDMLKRHQVDGII 120 Query: 121 LGSHTLEIGDYTHLNYPLVTIDRRIGDIPFVASDNENGGALAARLLIAKGCRKIGHLSGN 180 +GSHTLE Y ++ P+V IDR +IP+VASDN GG LA +LLI KGC+KI H+SG Sbjct: 121 IGSHTLEAEQYLNVKLPIVAIDRYYSNIPYVASDNYKGGILATKLLIQKGCKKIAHISGP 180 Query: 181 MKLDMLSNLRTTGFEREARQGGVKFVTYQTELDVFDEQIYNEIIRKMFTEHPDIDGVFAT 240 + L+ +N R F+ A Q V++ +T+L+ F+ + Y +I+R +F EHPDIDG+FA+ Sbjct: 181 LILNTPANNRYKAFKEVATQENVEYFVVETKLNRFEIEEYKKIVRGLFKEHPDIDGIFAS 240 Query: 241 SDLMALFVMKWCRTFGKEVPRDVRIIGYDDIDAASWYMPGLSTIKQPIKDMARRAVELLL 300 SDL+A V+ + K++P+D++I+GYDDI+ A+ +P L+T++QPIK++AR+A+EL+L Sbjct: 241 SDLIAASVISVAKELNKKIPQDLKIVGYDDINVANLVVPSLTTVRQPIKEIARKAIELIL 300 Query: 301 EQMDDKTVERETVLPVELVEREST 324 Q+D + VE+E +LP+ L+ERE+T Sbjct: 301 RQIDGEKVEKENILPITLIERETT 324 >B8DZA4.1 B8DZA4_DICTD Transcriptional regulator, LacI family Length = 325 Score = 366 bits (939), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 168/325 (51%), Positives = 243/325 (74%), Gaps = 1/325 (0%) Query: 1 MATINDVAEQAGVSVTTVSRVLNNRGYISEKTRQKVYQVMDELNYQPNELARSLLRKHSN 60 MA+I DVA++AGV+VTTVSRVLNNRGYISE+TR+KVY+ M+ELNYQPNELAR+L RK S Sbjct: 1 MASIRDVAKRAGVTVTTVSRVLNNRGYISEETRKKVYKAMEELNYQPNELARALYRKRSY 60 Query: 61 VLGLIIPSVAHPFFGELANAIESVAYQHGFKLLLCNSQLDSAKEREYVDMMRRNRVDGMI 120 +GLIIP V+HPFFGE+A IE AY G+K+LLCNS LD KE+EY++M++R++VDG+I Sbjct: 61 FIGLIIPDVSHPFFGEVAKYIEYYAYLRGYKILLCNSYLDEKKEKEYINMLKRHQVDGII 120 Query: 121 LGSHTLEIGDYTHLNYPLVTIDRRIG-DIPFVASDNENGGALAARLLIAKGCRKIGHLSG 179 +GSHTL++ DY +N P+V +DR + DIP+V SDN G +A LLI KGCR + H+SG Sbjct: 121 MGSHTLDVEDYKKVNLPIVALDRVLSEDIPYVTSDNYRGAVMATNLLIEKGCRFLAHISG 180 Query: 180 NMKLDMLSNLRTTGFEREARQGGVKFVTYQTELDVFDEQIYNEIIRKMFTEHPDIDGVFA 239 ++L+ +N R GF Q VK V +T L+ FD Y +I+ ++F ++P+IDGVFA Sbjct: 181 PLQLNTPANDRYYGFMHVVSQRSVKHVVVETRLNKFDINEYKDIVSQLFKKYPEIDGVFA 240 Query: 240 TSDLMALFVMKWCRTFGKEVPRDVRIIGYDDIDAASWYMPGLSTIKQPIKDMARRAVELL 299 +SDL+A V++ FGK+VP ++++G+DD++ AS P ++T++Q MA++A++L+ Sbjct: 241 SSDLIAAVVIRVAEDFGKKVPESLKVVGFDDVNIASIMKPSITTVRQYKDKMAQKAIDLI 300 Query: 300 LEQMDDKTVERETVLPVELVEREST 324 + +++ VE V+P++L+EREST Sbjct: 301 INKIEGNNVEVSNVIPIDLIEREST 325 >B5YAX3.1 B5YAX3_DICT6 Transcriptional regulator Length = 328 Score = 357 bits (917), Expect = 6e-97, Method: Compositional matrix adjust. Identities = 162/325 (49%), Positives = 240/325 (73%), Gaps = 1/325 (0%) Query: 1 MATINDVAEQAGVSVTTVSRVLNNRGYISEKTRQKVYQVMDELNYQPNELARSLLRKHSN 60 M ++ DVA++AGVS TTVSRVLNNRGYISE+TR+KVY+ M+ELNYQPNE+AR+L +K S Sbjct: 1 MPSLKDVAKRAGVSPTTVSRVLNNRGYISEETRRKVYKAMEELNYQPNEIARALFKKRSY 60 Query: 61 VLGLIIPSVAHPFFGELANAIESVAYQHGFKLLLCNSQLDSAKEREYVDMMRRNRVDGMI 120 LGLIIP ++HPFF E+ IE AY G+K+L+CNS LD KE+EY+ M++R++VDG+I Sbjct: 61 FLGLIIPDISHPFFAEITKYIEYYAYLKGYKVLICNSYLDGHKEKEYIKMLKRHQVDGII 120 Query: 121 LGSHTLEIGDYTHLNYPLVTIDRRIG-DIPFVASDNENGGALAARLLIAKGCRKIGHLSG 179 +GSHTL + DY +N P+V +DR I DIP + SDN G +A +LLI +GC+ + H+SG Sbjct: 121 MGSHTLNVEDYKSINLPIVALDRYISEDIPCITSDNFTGAIMATKLLIERGCKYLAHISG 180 Query: 180 NMKLDMLSNLRTTGFEREARQGGVKFVTYQTELDVFDEQIYNEIIRKMFTEHPDIDGVFA 239 ++L+ +N R GF + R+ G+K V +T+L+ F+ + Y +II+ +F +HP IDG+FA Sbjct: 181 PLELNTPANDRYYGFLKVVREKGIKHVVVETKLNKFEIEEYQKIIKDLFEKHPQIDGIFA 240 Query: 240 TSDLMALFVMKWCRTFGKEVPRDVRIIGYDDIDAASWYMPGLSTIKQPIKDMARRAVELL 299 +SDL+A V++ F K VP+D++++G+DDI AS P L+TI+Q MA++ +E+L Sbjct: 241 SSDLIAATVIRMADRFKKNVPKDLKVVGFDDIGLASLLRPSLTTIRQDKDKMAQKLIEVL 300 Query: 300 LEQMDDKTVERETVLPVELVEREST 324 +++++ K E + +LP+ L+EREST Sbjct: 301 IDKIEGKNAESKYILPISLIEREST 325 >Q8GM38.1 Q8GM38_BACME Repressor FruR Length = 327 Score = 301 bits (772), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 147/326 (45%), Positives = 229/326 (70%), Gaps = 4/326 (1%) Query: 2 ATINDVAEQAGVSVTTVSRVLNNRGYISEKTRQKVYQVMDELNYQPNELARSLLRKHSNV 61 A I+DVA+ AGVS TTVSRVLNNRGYIS++TR+ VY+ M E+NY PN++ARSL K +N+ Sbjct: 3 AKISDVAKIAGVSPTTVSRVLNNRGYISKETRENVYKAMKEINYFPNDIARSLFNKRTNL 62 Query: 62 LGLIIPSVAHPFFGELANAIESVAYQHGFKLLLCNSQLDSAKEREYVDMMRRNRVDGMIL 121 +G+I+P ++PFFGELA IES+ +K+LLCNS KE++YV+M+ RN+VDG+I Sbjct: 63 IGMIVPQTSNPFFGELAFHIESICASLNYKVLLCNSLNRIDKEKKYVEMLIRNQVDGVIA 122 Query: 122 GSHTLEIGDYTHLNYPLVTIDRRIG-DIPFVASDNENGGALAARLLIAKGCRKIGHLSGN 180 ++ I D + P+V +D + DIP V+SDN +GG A LLI+K C+ I H++G Sbjct: 123 VTYNRGIFDSESQSLPVVAVDHYLSTDIPTVSSDNYSGGKQATELLISKDCKHIIHINGP 182 Query: 181 MKLDMLSNLRTTGFEREARQGGVKFVTYQTELDVFDEQIYNEIIRKMFTEHPDIDGVFAT 240 +KL+ +NLR +E ++ G + +TY+ + FD I E I K+F E+P++DG+FA+ Sbjct: 183 LKLETPANLRRKAYENVMKKYGKQPITYEIS-NTFDRNIQRETISKVFEENPEVDGIFAS 241 Query: 241 SDLMALFVMKWCRTFGKEVPRDVRIIGYDDIDAASWYMPGLSTIKQPIKDMARRAVELLL 300 DL+A V+ + GK +PRD++I+GYD +A+ +PGL+T++QPI+ +A+ A+++LL Sbjct: 242 DDLLAALVVAEAQKRGKNIPRDLKIVGYDGTEASQTLLPGLTTVQQPIESIAQTAIDILL 301 Query: 301 EQMDDK--TVERETVLPVELVEREST 324 ++++ + + RE LPV+L+E ++T Sbjct: 302 KEIEGEFSNIPREICLPVKLLEGQTT 327 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,828,880,455 Number of extensions: 75105670 Number of successful extensions: 218334 Number of sequences better than 1.0e-05: 9428 Number of HSP's gapped: 205424 Number of HSP's successfully gapped: 9567 Length of query: 324 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 188 Effective length of database: 1,779,438,163 Effective search space: 334534374644 Effective search space used: 334534374644 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)