BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0049.0007.p (338 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A0KY00.1 A0KY00_SHESA Ferrochelatase EC=4.99.1.1 263 1e-68 Q0HHZ8.1 Q0HHZ8_SHESM Ferrochelatase EC=4.99.1.1 263 2e-68 Q0HU98.1 Q0HU98_SHESR Ferrochelatase EC=4.99.1.1 263 2e-68 C5BIF4.1 C5BIF4_9GAMM Ferrochelatase EC=4.99.1.1 259 2e-67 A3QF47.1 A3QF47_SHELP Ferrochelatase EC=4.99.1.1 246 2e-63 >A0KY00.1 A0KY00_SHESA Ferrochelatase EC=4.99.1.1 Length = 348 Score = 263 bits (673), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 141/340 (41%), Positives = 195/340 (57%), Gaps = 16/340 (4%) Query: 3 PPAPIGVILAQIGTPEAPTAKAVRPYLRRFLSDRRIIDYPPFFWQXXXXXXXXXXXXXXS 62 P GV+L +GTP+ PT KAV+ +L++FLSD R++D P+ WQ Sbjct: 18 PSPAFGVLLVNLGTPDEPTPKAVKRFLKQFLSDPRVVDLSPWLWQPILQGIILNTRPAKV 77 Query: 63 ALLYSQIWQKDGSPLLLHSLDQRAGLQRLLGNRYL----VELGLAYSAPSMEQAMGKLEA 118 A LY +W + GSPL++ S Q L L + VELG++Y PS+E KL+A Sbjct: 78 AKLYQSVWTEQGSPLMVISEQQAQKLATDLSATFNQTIPVELGMSYGNPSIESGFAKLKA 137 Query: 119 AGATRVVVVPLFPQYSSTTTASVYDAASFAALGRRSASGPVTKRFVPALRFMEAYYNEPG 178 GA R+VV+PL+PQYS +T ASV+DA A R +P LRF + Y++ Sbjct: 138 QGAERIVVLPLYPQYSCSTVASVFDAV---------AQYFTQVRDIPELRFSKQYFDHEA 188 Query: 179 YIWAMKEHLMQQISRLSTPPDYYVLSFHGIPRRYADTGDPYPLQCLETARLLAEAMGWET 238 YI A+ H +++ + D +LSFHGIP RYA GDPYP QC TA+LLA+A+ Sbjct: 189 YIAALA-HSVKRHWKTHGQADKLILSFHGIPLRYATEGDPYPEQCRATAKLLAQALELTD 247 Query: 239 GCWQAAFQSRFGREEWIGPSTSEVLKELAGRGIRRPMIFSPGLTTDCLETLHELAIEGRE 298 G WQ FQSRFG+EEW+ P E+L +L +G++ + P TDCLETL E++I G+E Sbjct: 248 GQWQVCFQSRFGKEEWLTPYADELLADLPRQGVKSVDVICPAFATDCLETLEEISIGGKE 307 Query: 299 HFAAGGGQPENLFAAPCLNDNEEWLSFLAELVERNALGWI 338 F GG+ + PCLND+E + L +LV+ A WI Sbjct: 308 TFLHAGGEAYHFI--PCLNDDELHIELLRQLVQEQAQPWI 345 >Q0HHZ8.1 Q0HHZ8_SHESM Ferrochelatase EC=4.99.1.1 Length = 348 Score = 263 bits (671), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 140/340 (41%), Positives = 195/340 (57%), Gaps = 16/340 (4%) Query: 3 PPAPIGVILAQIGTPEAPTAKAVRPYLRRFLSDRRIIDYPPFFWQXXXXXXXXXXXXXXS 62 P GV+L +GTP+ PT KAV+ +L++FLSD R++D P+ WQ Sbjct: 18 PSPAFGVLLVNLGTPDEPTPKAVKRFLKQFLSDPRVVDLSPWLWQPILQGIILNTRPAKV 77 Query: 63 ALLYSQIWQKDGSPLLLHSLDQRAGLQRLLGNRYL----VELGLAYSAPSMEQAMGKLEA 118 A LY +W + GSPL++ S Q L L + VELG++Y PS++ KL+A Sbjct: 78 AKLYQSVWTEQGSPLMVISEQQAQKLATDLSATFNQTIPVELGMSYGNPSIDSGFAKLKA 137 Query: 119 AGATRVVVVPLFPQYSSTTTASVYDAASFAALGRRSASGPVTKRFVPALRFMEAYYNEPG 178 GA R+VV+PL+PQYS +T ASV+DA A R +P LRF + Y++ Sbjct: 138 QGAERIVVLPLYPQYSCSTVASVFDAV---------AQYFTQVRDIPELRFSKQYFDHDA 188 Query: 179 YIWAMKEHLMQQISRLSTPPDYYVLSFHGIPRRYADTGDPYPLQCLETARLLAEAMGWET 238 YI A+ H +++ + D +LSFHGIP RYA GDPYP QC TA+LLA+A+ Sbjct: 189 YIAALA-HSVKRHWKTHGQADKLILSFHGIPLRYATEGDPYPEQCRSTAKLLAQALELTD 247 Query: 239 GCWQAAFQSRFGREEWIGPSTSEVLKELAGRGIRRPMIFSPGLTTDCLETLHELAIEGRE 298 G WQ FQSRFG+EEW+ P E+L +L +G++ + P TDCLETL E++I G+E Sbjct: 248 GQWQVCFQSRFGKEEWLTPYADELLADLPRQGVKSVDVICPAFATDCLETLEEISIGGKE 307 Query: 299 HFAAGGGQPENLFAAPCLNDNEEWLSFLAELVERNALGWI 338 F GG+ + PCLND+E + L +LV+ A WI Sbjct: 308 TFLHAGGEAYHFI--PCLNDDELHIELLRQLVQEQAQPWI 345 >Q0HU98.1 Q0HU98_SHESR Ferrochelatase EC=4.99.1.1 Length = 348 Score = 263 bits (671), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 140/340 (41%), Positives = 195/340 (57%), Gaps = 16/340 (4%) Query: 3 PPAPIGVILAQIGTPEAPTAKAVRPYLRRFLSDRRIIDYPPFFWQXXXXXXXXXXXXXXS 62 P GV+L +GTP+ PT KAV+ +L++FLSD R++D P+ WQ Sbjct: 18 PSPAFGVLLVNLGTPDEPTPKAVKRFLKQFLSDPRVVDLSPWLWQPILQGIILNTRPAKV 77 Query: 63 ALLYSQIWQKDGSPLLLHSLDQRAGLQRLLGNRYL----VELGLAYSAPSMEQAMGKLEA 118 A LY +W + GSPL++ S Q L L + VELG++Y PS++ KL+A Sbjct: 78 AKLYQSVWTEQGSPLMVISEQQAQKLATDLSATFNQTIPVELGMSYGNPSIDSGFAKLKA 137 Query: 119 AGATRVVVVPLFPQYSSTTTASVYDAASFAALGRRSASGPVTKRFVPALRFMEAYYNEPG 178 GA R+VV+PL+PQYS +T ASV+DA A R +P LRF + Y++ Sbjct: 138 QGAERIVVLPLYPQYSCSTVASVFDAV---------AQYFTQVRDIPELRFSKQYFDHEA 188 Query: 179 YIWAMKEHLMQQISRLSTPPDYYVLSFHGIPRRYADTGDPYPLQCLETARLLAEAMGWET 238 YI A+ H +++ + D +LSFHGIP RYA GDPYP QC TA+LLA+A+ Sbjct: 189 YIAALA-HSVKRHWKTHRQADKLILSFHGIPLRYATEGDPYPEQCRATAKLLAQALELTD 247 Query: 239 GCWQAAFQSRFGREEWIGPSTSEVLKELAGRGIRRPMIFSPGLTTDCLETLHELAIEGRE 298 G WQ FQSRFG+EEW+ P E+L +L +G++ + P TDCLETL E++I G+E Sbjct: 248 GQWQVCFQSRFGKEEWLTPYADELLADLPRQGVKSVDVICPAFATDCLETLEEISIGGKE 307 Query: 299 HFAAGGGQPENLFAAPCLNDNEEWLSFLAELVERNALGWI 338 F GG+ + PCLND+E + L +LV+ A WI Sbjct: 308 TFLHAGGEAYHFI--PCLNDDELHIELLRQLVQEQAQPWI 345 >C5BIF4.1 C5BIF4_9GAMM Ferrochelatase EC=4.99.1.1 Length = 366 Score = 259 bits (663), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 139/334 (41%), Positives = 195/334 (58%), Gaps = 16/334 (4%) Query: 8 GVILAQIGTPEAPTAKAVRPYLRRFLSDRRIIDYPPFFWQXXXXXXXXXXXXXXSALLYS 67 GV+L +GTP APTAKA++PYL++FLSD R++++P W SA Y+ Sbjct: 17 GVLLVNLGTPAAPTAKALKPYLKQFLSDPRVVEFPRLLWWLILNGIILNVRPRKSAAAYA 76 Query: 68 QIWQKDGSPLLLHSLDQRAGL----QRLLGNRYLVELGLAYSAPSMEQAMGKLEAAGATR 123 ++W + GSPL +H+ DQ + L QR ++ +V + Y +PSM L G + Sbjct: 77 KVWTERGSPLAIHTADQASALNVRLQRRFDDQVVVAWAMRYGSPSMADVQQSLFDQGVQQ 136 Query: 124 VVVVPLFPQYSSTTTASVYDAASFAALGRRSASGPVTKRFVPALRFMEAYYNEPGYIWAM 183 ++V+PL+PQYS+ TT S +DA S A RR R++PALRF+ Y++ PGYI A+ Sbjct: 137 LLVIPLYPQYSAATTGSTFDALS-ADFQRR--------RWLPALRFVNQYHDNPGYIAAL 187 Query: 184 KEHLMQQISRLSTPPDYYVLSFHGIPRRYADTGDPYPLQCLETARLLAEAMGWETGCWQA 243 E + Q + D +LS+HG+P RY GDPY QCL T+RLLAEA+ Sbjct: 188 AERVRQHWQN-NGRADKLILSYHGVPLRYLHAGDPYHCQCLATSRLLAEALQLTESEVIT 246 Query: 244 AFQSRFGREEWIGPSTSEVLKELAGRGIRRPMIFSPGLTTDCLETLHELAIEGREHFAAG 303 +FQSRFGREEW+ P T +LK+L G G++ I PG ++DCLET+ E+ E RE+F Sbjct: 247 SFQSRFGREEWLQPYTDVLLKQLPGAGVKSVQIMCPGFSSDCLETIEEIGEENREYFLQN 306 Query: 304 GGQPENLFAAPCLNDNEEWLSFLAELVERNALGW 337 GG EN P LN E+ + L +LV N GW Sbjct: 307 GG--ENYQYIPALNAGEDHIDVLEQLVLDNLQGW 338 >A3QF47.1 A3QF47_SHELP Ferrochelatase EC=4.99.1.1 Length = 337 Score = 246 bits (628), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 138/341 (40%), Positives = 196/341 (57%), Gaps = 16/341 (4%) Query: 2 LPPAPIGVILAQIGTPEAPTAKAVRPYLRRFLSDRRIIDYPPFFWQXXXXXXXXXXXXXX 61 L PA +GV+L +GTP+ PT K V+ +L++FLSD R++D P+ W+ Sbjct: 7 LSPAKLGVLLVNLGTPDTPTPKDVKQFLKQFLSDPRVVDLNPWIWKPILNGIILNTRPKA 66 Query: 62 SALLYSQIWQKDGSPLLLHSLDQRAGLQRLLGNRY----LVELGLAYSAPSMEQAMGKLE 117 A LY IW +GSPL++ S QR L +L R+ VELG++Y PS+ + KL Sbjct: 67 VAKLYESIWWPEGSPLMVISERQREALSAILKARHGSDIPVELGMSYGNPSLSSGIDKLV 126 Query: 118 AAGATRVVVVPLFPQYSSTTTASVYDAASFAALGRRSASGPVTKRFVPALRFMEAYYNEP 177 A G R+VV+PL+PQYS +T A V+DA + GRR+ P RF + Y+ P Sbjct: 127 AQGVERLVVLPLYPQYSCSTVAPVFDAIASDYKGRRN---------YPETRFSKEYFEHP 177 Query: 178 GYIWAMKEHLMQQISRLSTPPDYYVLSFHGIPRRYADTGDPYPLQCLETARLLAEAMGWE 237 YI A+ + + D ++SFHG+P RY GDPY QC TA LLA A+G Sbjct: 178 AYIAALAGSVRRHWQDKGQG-DCLLMSFHGVPLRYVTEGDPYQRQCQRTAELLAAALGLT 236 Query: 238 TGCWQAAFQSRFGREEWIGPSTSEVLKELAGRGIRRPMIFSPGLTTDCLETLHELAIEGR 297 W+ FQS+FG+EEW+ P+T +L+ L G+G++R I P DCLETL E++I G+ Sbjct: 237 ESQWRLCFQSKFGKEEWLTPATDALLESLPGKGVKRVDILCPAFAVDCLETLEEISIGGK 296 Query: 298 EHFAAGGGQPENLFAAPCLNDNEEWLSFLAELVERNALGWI 338 E F GG E+ PCLN++E + LA+LV++ A GW+ Sbjct: 297 ESFIEAGG--EDYHFIPCLNEDEAHMQLLADLVDQQAAGWL 335 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,084,475,204 Number of extensions: 84937571 Number of successful extensions: 196103 Number of sequences better than 1.0e-05: 1291 Number of HSP's gapped: 192738 Number of HSP's successfully gapped: 1291 Length of query: 338 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 202 Effective length of database: 1,779,438,163 Effective search space: 359446508926 Effective search space used: 359446508926 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)