BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0045.0008.p (182 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8EL51.1 Q8EL51_OCEIH Transcriptional regulator (TetR-family) 171 2e-41 C3HSA7.1 C3HSA7_BACTU Transcriptional regulator 161 2e-38 B3K973.1 B3K973_9BACI Regulatory protein TetR 155 1e-36 C0ZET9.1 C0ZET9_BREBN Probable transcriptional regulator 146 7e-34 B1D9H0.1 B1D9H0_9BACL Transcriptional regulator, TetR family 129 1e-28 >Q8EL51.1 Q8EL51_OCEIH Transcriptional regulator (TetR-family) Length = 171 Score = 171 bits (433), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 83/173 (47%), Positives = 120/173 (69%), Gaps = 4/173 (2%) Query: 8 VRTKEEAASVNRREQILEAAVVVFAEHGYFKATTAQVAEKVGISQPYIFKLFKNKEELFV 67 VR+ +E NR+E+ILEA + VFA+ GY TTA VAEK GISQPY+F+ FK KE+LF+ Sbjct: 2 VRSSKE----NRKEEILEAGLEVFAKRGYHNTTTAHVAEKAGISQPYVFRFFKTKEKLFI 57 Query: 68 AALDRAFERTIRTFSAVEASGDTLLEESIRVYEQMMETHPSEIILQVQALGIRDEAIRRS 127 AALDRAFER + F V +S + L+++ I YE++ E HP+EI LQV + + +EAIR + Sbjct: 58 AALDRAFERILLAFKNVHSSPEQLVDKMIEAYEELSELHPNEIALQVIGISVTEEAIRNA 117 Query: 128 MQTGMNKVTQLMENKFTAAGVAHPEVEVSTFMANGMLCHIAMALEMPELKPKH 180 + G++ + +F AG+ + E EV+TF+A GMLC+I+ L++PEL K+ Sbjct: 118 TKKGLSNIQNYTLERFKDAGIENVESEVTTFLARGMLCNISYFLDLPELIAKN 170 >C3HSA7.1 C3HSA7_BACTU Transcriptional regulator Length = 171 Score = 161 bits (408), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 73/159 (45%), Positives = 114/159 (71%) Query: 18 NRREQILEAAVVVFAEHGYFKATTAQVAEKVGISQPYIFKLFKNKEELFVAALDRAFERT 77 NR+E+ILEA + VFAE GY+ TTA +AEKVGISQPYIF+ F+ KE+LFVAAL+RAFER Sbjct: 7 NRKEEILEAGLEVFAEKGYYNTTTALIAEKVGISQPYIFRFFRTKEDLFVAALERAFERI 66 Query: 78 IRTFSAVEASGDTLLEESIRVYEQMMETHPSEIILQVQALGIRDEAIRRSMQTGMNKVTQ 137 ++ F VE++ + ++ + + YE++ ++P+EI LQV L + ++ IR + G++ + Sbjct: 67 LQAFKNVESNPEDIVIKMVEAYEKLSVSYPNEIALQVIGLSVTEDTIRNCTKKGLSCIRS 126 Query: 138 LMENKFTAAGVAHPEVEVSTFMANGMLCHIAMALEMPEL 176 + +F A V + E EV+TF+A G+LC+++ L++PEL Sbjct: 127 YILERFQLANVPNAEKEVTTFLARGILCNVSYYLDLPEL 165 >B3K973.1 B3K973_9BACI Regulatory protein TetR Length = 172 Score = 155 bits (392), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 78/167 (46%), Positives = 115/167 (68%), Gaps = 3/167 (1%) Query: 16 SVNRREQILEAAVVVFAEHGYFKATTAQVAEKVGISQPYIFKLFKNKEELFVAALDRAFE 75 S NRR +I+ AA+ VFAE GY++ATTAQVAE+ ISQPY+++ F KE L V +L +++ Sbjct: 7 SANRRNEIVAAAIEVFAEIGYYRATTAQVAERAAISQPYVYRFF-TKESLLVESLTVSWK 65 Query: 76 RTIRTFSAV-EASGDTLLEES-IRVYEQMMETHPSEIILQVQALGIRDEAIRRSMQTGMN 133 R ++ F V E++ LE IR YE ++++H SEI+LQ+QA I++ IR +MQ GMN Sbjct: 66 RIVQAFQGVIESAAPEELETGLIRAYEGIVQSHRSEILLQMQAQTIQEAPIREAMQQGMN 125 Query: 134 KVTQLMENKFTAAGVAHPEVEVSTFMANGMLCHIAMALEMPELKPKH 180 +V L++N F AG + + S F+A GMLC++AMA++MP + PK Sbjct: 126 EVKDLVQNAFVKAGFEDADKKTSDFLARGMLCNVAMAMDMPNMMPKR 172 >C0ZET9.1 C0ZET9_BREBN Probable transcriptional regulator Length = 168 Score = 146 bits (369), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 81/164 (49%), Positives = 116/164 (70%), Gaps = 2/164 (1%) Query: 15 ASVNRREQILEAAVVVFAEHGYFKATTAQVAEKVGISQPYIFKLFKNKEELFVAALDRAF 74 ASVNR+ +I+ AA+ VFAE GYF+ATTAQVAE+ ISQPYIFK F +KE L +AAL+ ++ Sbjct: 2 ASVNRKTEIISAAIEVFAEIGYFRATTAQVAERAKISQPYIFKFFASKEALLLAALEASW 61 Query: 75 ERTIRTFSAV--EASGDTLLEESIRVYEQMMETHPSEIILQVQALGIRDEAIRRSMQTGM 132 ER I +F V AS + L + I+ YE+++ +H +EI+LQ+QA I++ IR +M+ Sbjct: 62 ERIIDSFRLVVESASKEQLETDLIKAYEKILASHQNEILLQMQAQTIQEPLIREAMREAF 121 Query: 133 NKVTQLMENKFTAAGVAHPEVEVSTFMANGMLCHIAMALEMPEL 176 V Q++ F AG+A+PE F+A GMLC+I++AL+MPEL Sbjct: 122 RGVRQIVLTAFREAGIANPEERTLIFLARGMLCNISVALDMPEL 165 >B1D9H0.1 B1D9H0_9BACL Transcriptional regulator, TetR family Length = 181 Score = 129 bits (324), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 67/168 (39%), Positives = 106/168 (63%) Query: 9 RTKEEAASVNRREQILEAAVVVFAEHGYFKATTAQVAEKVGISQPYIFKLFKNKEELFVA 68 R K+ A NR+EQIL+AA +FA +GY+K TTA VA +VG++QPY+F FK+KE L++A Sbjct: 4 REKDFHAVTNRKEQILDAAASLFANNGYYKTTTAMVAAEVGVTQPYVFHFFKSKEVLYLA 63 Query: 69 ALDRAFERTIRTFSAVEASGDTLLEESIRVYEQMMETHPSEIILQVQALGIRDEAIRRSM 128 L+RA +R + FS VEA + L + ++M TH E +L +Q+ + +R + Sbjct: 64 VLERAQKRLLHAFSQVEAPAEMLHHHMGEAFNELMATHRDETLLCMQSYTTPEPNVRVIV 123 Query: 129 QTGMNKVTQLMENKFTAAGVAHPEVEVSTFMANGMLCHIAMALEMPEL 176 + +V QL+ +F AG+++P + STF+A GM+ ++ LE+P L Sbjct: 124 KQRFAEVHQLITERFERAGISNPSQQASTFIACGMVITMSEILELPIL 171 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.130 0.349 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 884,282,222 Number of extensions: 29297849 Number of successful extensions: 122933 Number of sequences better than 1.0e-05: 256 Number of HSP's gapped: 123326 Number of HSP's successfully gapped: 256 Length of query: 182 Length of database: 3,060,696,203 Length adjustment: 127 Effective length of query: 55 Effective length of database: 1,864,227,298 Effective search space: 102532501390 Effective search space used: 102532501390 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)