BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0044.0015.p (268 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8N7.1 B3K8N7_9BACI Beta-lactamase domain protein 446 e-124 B1DC50.1 B1DC50_9BACL Beta-lactamase domain protein 364 4e-99 Q9K5R5.1 Q9K5R5_BACHD BH4023 protein 293 9e-78 B7IS06.1 B7IS06_BACC2 Metallo-beta-lactamase family protein 289 2e-76 B7HGC2.1 B7HGC2_BACC4 Metallo-beta-lactamase family protein 289 2e-76 >B3K8N7.1 B3K8N7_9BACI Beta-lactamase domain protein Length = 267 Score = 446 bits (1147), Expect = e-124, Method: Compositional matrix adjust. Identities = 209/267 (78%), Positives = 238/267 (89%) Query: 1 MGISFTVLSSGSTGNVTVVRNGETTLMIDAGLSAKRIDELLAMRELTGQDIDGILVTHEH 60 MGISF+VLSSGSTGN T+VRN +TTL+IDAGLSA+RIDELL RE+ G++IDGILVTHEH Sbjct: 1 MGISFSVLSSGSTGNATIVRNEDTTLLIDAGLSARRIDELLKEREMMGEEIDGILVTHEH 60 Query: 61 SDHIKGLGAMARKYDLPIYANTNTWGAIEKGIGNIAEQNRVVLETGQYRDFGSLRVESFA 120 SDHI+GLGA+ARKY+LPIYAN TW A+ K +G IAE+NR+VLE+ + +DFG+LRVE F Sbjct: 61 SDHIRGLGAVARKYNLPIYANEKTWEAMSKSLGKIAEENRIVLESHEVKDFGTLRVEPFE 120 Query: 121 ISHDAAEPVGYNFYDGKEKLCVATDLGYVSDKVRTAISDADVLVLEANHDIEMLRMGRYP 180 ISHDAA PVGY FYDG EKL VATDLGYVSDKV+ A+ +DVLVLEANHDIEMLRMGRYP Sbjct: 121 ISHDAAAPVGYCFYDGDEKLGVATDLGYVSDKVKKALDGSDVLVLEANHDIEMLRMGRYP 180 Query: 181 WNTKRRILGDLGHLSNEAAGAALSEILTGRTKRTYLAHLSRDHNMMDLAKMSVRGAMEDR 240 WNTKRRILGD+GHLSN +AG ALSE+LTG TKRTYLAHLS DHNMMDLA+M+VR MEDR Sbjct: 181 WNTKRRILGDMGHLSNNSAGDALSELLTGDTKRTYLAHLSLDHNMMDLARMTVRDTMEDR 240 Query: 241 GCFFKDSEFRLCDTYYDRPTPWDKVSQ 267 GCFFKDSEF+LCDTYYDRPTPWDKV + Sbjct: 241 GCFFKDSEFKLCDTYYDRPTPWDKVGE 267 >B1DC50.1 B1DC50_9BACL Beta-lactamase domain protein Length = 268 Score = 364 bits (935), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 170/265 (64%), Positives = 210/265 (79%) Query: 1 MGISFTVLSSGSTGNVTVVRNGETTLMIDAGLSAKRIDELLAMRELTGQDIDGILVTHEH 60 MG++FTVL SGSTGN T+V NG+ +++DAGLS K+I+EL+ + ++G + + VTHEH Sbjct: 1 MGLTFTVLGSGSTGNATIVSNGDKMVLVDAGLSMKKIEELMRDQGVSGHQLSALFVTHEH 60 Query: 61 SDHIKGLGAMARKYDLPIYANTNTWGAIEKGIGNIAEQNRVVLETGQYRDFGSLRVESFA 120 SDHIKGLGA ARKY+LPI+AN TWG +E+ +GNI + RV++ETG+ FG++ V S+ Sbjct: 61 SDHIKGLGAFARKYELPIFANEGTWGGMERHVGNIEPEKRVIMETGESLRFGTMEVCSYP 120 Query: 121 ISHDAAEPVGYNFYDGKEKLCVATDLGYVSDKVRTAISDADVLVLEANHDIEMLRMGRYP 180 ISHDAAEPVGY F D EKL +ATDLGY+SDKV+ AI D+DVLVLE+NHD EMLRMGRYP Sbjct: 121 ISHDAAEPVGYTFVDNGEKLSLATDLGYMSDKVKQAIIDSDVLVLESNHDTEMLRMGRYP 180 Query: 181 WNTKRRILGDLGHLSNEAAGAALSEILTGRTKRTYLAHLSRDHNMMDLAKMSVRGAMEDR 240 WN KRRIL D+GHLSN AAG AL E+LT RTKR YLAHLS DHN+MDLA ++VR MED Sbjct: 181 WNIKRRILSDVGHLSNVAAGEALCELLTDRTKRVYLAHLSLDHNLMDLAMLTVRNVMEDN 240 Query: 241 GCFFKDSEFRLCDTYYDRPTPWDKV 265 G FFK +E L TY+DRPT WD+V Sbjct: 241 GIFFKQNENPLRPTYHDRPTAWDEV 265 >Q9K5R5.1 Q9K5R5_BACHD BH4023 protein Length = 264 Score = 293 bits (751), Expect = 9e-78, Method: Compositional matrix adjust. Identities = 137/261 (52%), Positives = 186/261 (71%), Gaps = 1/261 (0%) Query: 1 MGISFTVLSSGSTGNVTVVRNGETTLMIDAGLSAKRIDELLAMRELTGQDIDGILVTHEH 60 M + F+VL+SGSTGN V + L++DAGLS K++DEL + ++GILVTHEH Sbjct: 1 MSLRFSVLASGSTGNALYVETDKQKLLVDAGLSGKKMDELFQKIDCDPSQLNGILVTHEH 60 Query: 61 SDHIKGLGAMARKYDLPIYANTNTWGAIEKGIGNIAEQNRVVLETGQYRDFGSLRVESFA 120 SDHIKG+G +ARKY+LPIYAN TW A+EK +G + R E G+ + F L VESF Sbjct: 61 SDHIKGVGIVARKYNLPIYANAKTWQAMEKALGTLTTDQRFHFEIGEVKTFADLEVESFG 120 Query: 121 ISHDAAEPVGYNFYDGKEKLCVATDLGYVSDKVRTAISDADVLVLEANHDIEMLRMGRYP 180 +SHDAAEP+ Y F+ +KL +ATD+GYVS++++ I +AD L+ EANHD+ MLRMGRYP Sbjct: 121 VSHDAAEPMFYVFHHDGKKLVLATDMGYVSERIKKTIENADTLIFEANHDLNMLRMGRYP 180 Query: 181 WNTKRRILGDLGHLSNEAAGAALSEILTGRTKRTYLAHLSRDHNMMDLAKMSVRGAMEDR 240 WN KRRIL D+GH+SNE A AL+E++ RT+R YLAHLS D+NM +LA+++V ++++ Sbjct: 181 WNVKRRILSDVGHVSNEDAAYALAEVIGDRTERIYLAHLSLDNNMKELARLTVEQVLQEQ 240 Query: 241 GCFFKDSEFRLCDTYYDRPTP 261 G + FRL DT +PTP Sbjct: 241 GLAVGE-RFRLYDTDPYKPTP 260 >B7IS06.1 B7IS06_BACC2 Metallo-beta-lactamase family protein Length = 264 Score = 289 bits (739), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 137/260 (52%), Positives = 179/260 (68%), Gaps = 1/260 (0%) Query: 1 MGISFTVLSSGSTGNVTVVRNGETTLMIDAGLSAKRIDELLAMRELTGQDIDGILVTHEH 60 MG+ F+VL+SGSTGN+ V E L++DAGLS K + L EL D+ GILVTHEH Sbjct: 1 MGLHFSVLASGSTGNMLYVGTDEKKLLVDAGLSGKATEALFKQAELNINDVSGILVTHEH 60 Query: 61 SDHIKGLGAMARKYDLPIYANTNTWGAIEKGIGNIAEQNRVVLETGQYRDFGSLRVESFA 120 SDHIKGLG +ARKYDLP+YAN TW A+E IGNI + + + G + FG + VESF Sbjct: 61 SDHIKGLGVLARKYDLPVYANEKTWNAMEHLIGNIPTEQKFIFSVGDVKTFGDIEVESFG 120 Query: 121 ISHDAAEPVGYNFYDGKEKLCVATDLGYVSDKVRTAISDADVLVLEANHDIEMLRMGRYP 180 +SHDAAEP+ Y F++ KL + TD GYVSD+++ I A+ V E+NHD+EMLRMGRYP Sbjct: 121 VSHDAAEPMFYAFHNNNRKLALITDTGYVSDRMKGVIKGANAFVFESNHDVEMLRMGRYP 180 Query: 181 WNTKRRILGDLGHLSNEAAGAALSEILTGRTKRTYLAHLSRDHNMMDLAKMSVRGAMEDR 240 W+ KRRIL D+GH+ NE A A+++++T TK YLAHLS D+NM +LA+MSV +E++ Sbjct: 181 WSIKRRILSDVGHVCNEDAALAMADVITDETKHIYLAHLSLDNNMKELARMSVSQVLEEK 240 Query: 241 GCFFKDSEFRLCDTYYDRPT 260 G F F + DT PT Sbjct: 241 G-FGVGESFEIHDTDPKMPT 259 >B7HGC2.1 B7HGC2_BACC4 Metallo-beta-lactamase family protein Length = 264 Score = 289 bits (739), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 137/260 (52%), Positives = 179/260 (68%), Gaps = 1/260 (0%) Query: 1 MGISFTVLSSGSTGNVTVVRNGETTLMIDAGLSAKRIDELLAMRELTGQDIDGILVTHEH 60 MG+ F+VL+SGSTGN+ V E L++DAGLS K + L EL D+ GILVTHEH Sbjct: 1 MGLHFSVLASGSTGNMLYVGTDEKKLLVDAGLSGKATEALFKQAELNINDVSGILVTHEH 60 Query: 61 SDHIKGLGAMARKYDLPIYANTNTWGAIEKGIGNIAEQNRVVLETGQYRDFGSLRVESFA 120 SDHIKGLG +ARKYDLP+YAN TW A+E IGNI + + + G + FG + VESF Sbjct: 61 SDHIKGLGVLARKYDLPVYANEKTWNAMEHLIGNIPTEQKFIFSVGDVKTFGDIEVESFG 120 Query: 121 ISHDAAEPVGYNFYDGKEKLCVATDLGYVSDKVRTAISDADVLVLEANHDIEMLRMGRYP 180 +SHDAAEP+ Y F++ KL + TD GYVSD+++ I A+ V E+NHD+EMLRMGRYP Sbjct: 121 VSHDAAEPMFYAFHNNNRKLALITDTGYVSDRMKGVIKGANAFVFESNHDVEMLRMGRYP 180 Query: 181 WNTKRRILGDLGHLSNEAAGAALSEILTGRTKRTYLAHLSRDHNMMDLAKMSVRGAMEDR 240 W+ KRRIL D+GH+ NE A A+++++T TK YLAHLS D+NM +LA+MSV +E++ Sbjct: 181 WSIKRRILSDVGHVCNEDAALAMADVITDETKHIYLAHLSLDNNMKELARMSVSQVLEEK 240 Query: 241 GCFFKDSEFRLCDTYYDRPT 260 G F F + DT PT Sbjct: 241 G-FGVGESFEIHDTDPKMPT 259 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,536,991,035 Number of extensions: 61088830 Number of successful extensions: 161965 Number of sequences better than 1.0e-05: 714 Number of HSP's gapped: 161826 Number of HSP's successfully gapped: 715 Length of query: 268 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 135 Effective length of database: 1,807,701,208 Effective search space: 244039663080 Effective search space used: 244039663080 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 130 (54.7 bits)