BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0042.0012.p (384 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KCE0.1 B3KCE0_9BACI Copper amine oxidase domain protein 415 e-114 B5Y635.1 B5Y635_COPPD Copper amine oxidase N-domain family 127 2e-27 Q3AA51.1 Q3AA51_CARHZ Conserved domain protein 110 2e-22 B5Y710.1 B5Y710_COPPD Copper amine oxidase N-domain family 107 2e-21 A6TUG6.1 A6TUG6_ALKMQ Copper amine oxidase domain protein 106 3e-21 >B3KCE0.1 B3KCE0_9BACI Copper amine oxidase domain protein Length = 377 Score = 415 bits (1067), Expect = e-114, Method: Compositional matrix adjust. Identities = 202/347 (58%), Positives = 260/347 (74%), Gaps = 1/347 (0%) Query: 36 YVDKDNHAFIPLRFLNGFAGIQAGVSGQNGKEMTLSKNGTTVVLVSGQASASVGGKSVKL 95 YVDK++ +FI + L + G++ + K++ ++++ T + L G +A V GK ++ Sbjct: 30 YVDKNSQSFISVGVLKTYDGVKVAYTAAE-KKLNITRDDTALTLYLGSRNAYVNGKKLQA 88 Query: 96 SERPFSGNGTTYVPLSFISQTFGLQLVWNKTSASLTLAAGDDSATLPVLSGALISASSPA 155 PFS NG+TYVPL F+SQ GL+L W+ ++L + G S TLPVLSG +++ SS A Sbjct: 89 KAAPFSENGSTYVPLQFVSQHLGLKLSWSNNRSTLNITDGSVSNTLPVLSGNMMTGSSKA 148 Query: 156 AVSSRHTYTVGGRSFPVQMVTVSLLHPALKLDVVLAGNTVGKTEALGSIAKRSGAVAAIN 215 S+R T+ VG RSF Q+VTVSLLHP ++LDVVLAGN GK E L SIAKRS AV AIN Sbjct: 149 VTSARKTFKVGARSFSAQVVTVSLLHPKVELDVVLAGNKAGKVEDLRSIAKRSNAVVAIN 208 Query: 216 GTFFDAYTDAAYKAPYGYIISRGKMLKDSPADKRTVFAYDNNLLAELIPGSQFLARFNAG 275 GTFFDAYT AYKAPYGY++S+G + + D RT+F YD+N LA ++PG F + + G Sbjct: 209 GTFFDAYTSGAYKAPYGYLVSKGNIFHKASGDNRTIFTYDSNNLATMMPGLDFKSVYETG 268 Query: 276 TVTGAIQAGPRLLVDGKVALNVAAEGFRDPKILTGGGSRSALGLTRDHKLILLTSGGATI 335 + GA+QAGPRLL +GKV L+V EGF+DPKILTGGG+RSALG+T+DHKLILLT+GGATI Sbjct: 269 RMEGALQAGPRLLTNGKVTLDVKKEGFKDPKILTGGGARSALGITKDHKLILLTTGGATI 328 Query: 336 PQLAQIMKQAGAYQAMNLDGGASSGLFYSGKYLTSPGRLISNALVVK 382 PQLA+IMKQAGAYQAMNLDGGASSGL+Y+G YLT+PGR ISNA+VVK Sbjct: 329 PQLAEIMKQAGAYQAMNLDGGASSGLYYNGSYLTTPGRQISNAIVVK 375 >B5Y635.1 B5Y635_COPPD Copper amine oxidase N-domain family Length = 468 Score = 127 bits (319), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 62/110 (56%), Positives = 80/110 (72%) Query: 272 FNAGTVTGAIQAGPRLLVDGKVALNVAAEGFRDPKILTGGGSRSALGLTRDHKLILLTSG 331 + G + GA+ AGP L+ DGK+ +N AE + PKI SRSALGLT+D+KL+++T Sbjct: 356 WQQGVIEGALSAGPHLITDGKITVNPEAENYTIPKITEYSMSRSALGLTKDNKLLMVTVS 415 Query: 332 GATIPQLAQIMKQAGAYQAMNLDGGASSGLFYSGKYLTSPGRLISNALVV 381 A I LA IM++ GAY AMN+DGGASSGL+Y GK LT+PGR +SNALVV Sbjct: 416 SAKIEDLATIMQKLGAYNAMNIDGGASSGLYYKGKLLTTPGRDLSNALVV 465 Score = 114 bits (284), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/228 (32%), Positives = 115/228 (50%), Gaps = 28/228 (12%) Query: 39 KDNHAFIPLRFLNGFAGIQAGVSGQNGKEMTLSKNGTTVVLVSGQASASVGGKSVKLSER 98 +D F+P+R+++ + G Q + Q K +T+ + T+ L G + A + GK V L Sbjct: 28 RDGRVFLPIRYISEYFGAQVTWNDQT-KTVTVKQGSKTISLQIGNSIAQIDGKEVSLDVP 86 Query: 99 PFSGNGTTYVPLSFISQTFGLQLVWNKTSASLTLAAGDDSATLPVLSGALISASSPAAVS 158 F TYVPL FI + FG + W++T ++ + AVS Sbjct: 87 AFINGARTYVPLRFIGEAFGRYVDWDQTERAVYIDTD--------------------AVS 126 Query: 159 SRHTYTVGGRSFPVQMVTVSLLHPALKLDVVLAGNTVGKTEALGSIAKRSGAVAAINGTF 218 S + GG++F V++V V L +P + L + N +G TE+L S+A+RS A+AAINGTF Sbjct: 127 STMQMSFGGKTFNVKVVKVFLNNPHVDLKIAYGQNQIGLTESLLSMAQRSNAIAAINGTF 186 Query: 219 FDAYTDAAYKAPYGYIISRGKM----LKDSPADKRTVFAYDNNLLAEL 262 F AY K P G +I G++ +D PA T F + + A++ Sbjct: 187 FRAYETTNPKEPSGNLIIDGRIEHLCFRDKPA---TTFGFTKDGRADI 231 >Q3AA51.1 Q3AA51_CARHZ Conserved domain protein Length = 356 Score = 110 bits (276), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 63/155 (40%), Positives = 96/155 (61%), Gaps = 9/155 (5%) Query: 230 PYGYIISRGKMLKDSPADKRTVFAYDNNLLAELIPGSQFLARFNAGTVTGAIQAGPRLLV 289 P G++++ G + P D ++N+ ++ P +Q ++ ++AGP L+ Sbjct: 211 PQGFVLNTGSL---CPPDN----LLNSNVTLKIEPENQENVLWSKAY--AVLEAGPYLVK 261 Query: 290 DGKVALNVAAEGFRDPKILTGGGSRSALGLTRDHKLILLTSGGATIPQLAQIMKQAGAYQ 349 +GK+ + E F KI G +RS +G+T++ KL+L+T ATI + A IM++ GAY Sbjct: 262 EGKIIADPLKENFTHYKIKDGSFARSGIGVTKNKKLLLVTVNRATIKEWAIIMQKLGAYY 321 Query: 350 AMNLDGGASSGLFYSGKYLTSPGRLISNALVVKTN 384 AMNLDGGASSGL+ +GKYLT PGRL+SNALV+ N Sbjct: 322 AMNLDGGASSGLYVNGKYLTKPGRLLSNALVISLN 356 Score = 63.2 bits (152), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 32/87 (36%), Positives = 51/87 (58%), Gaps = 2/87 (2%) Query: 165 VGGRSFPVQMVTVSLLHPALKLDVVLAGNTVGKTEALGSIAKRSGAVAAINGTFFDAYTD 224 + ++F V+ V V L LK+ VLA N +G+ E+L S+ KR + ING FF AY Sbjct: 38 INNKNFTVKGVIVDLNTKKLKMQTVLAKNQIGQVESLESMVKRKKGLIGINGAFFSAYD- 96 Query: 225 AAYKAPYGYIISRGKMLKDSPADKRTV 251 AYK PYG ++ G++++ ++ +V Sbjct: 97 -AYKEPYGNLMIDGRLIRKGNGERCSV 122 >B5Y710.1 B5Y710_COPPD Copper amine oxidase N-domain family Length = 485 Score = 107 bits (267), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 53/110 (48%), Positives = 77/110 (70%) Query: 272 FNAGTVTGAIQAGPRLLVDGKVALNVAAEGFRDPKILTGGGSRSALGLTRDHKLILLTSG 331 + G + G + AGPRL+ +G++ L+ A+E PKI +RSALG+T++++L+++T Sbjct: 373 WQEGVIWGTLSAGPRLITNGEITLDPASELLDIPKITGQPLTRSALGITQNNELLMVTVS 432 Query: 332 GATIPQLAQIMKQAGAYQAMNLDGGASSGLFYSGKYLTSPGRLISNALVV 381 TI LA IMK GAY AMNLDGGAS+ L+ +GK+L +P R ISNAL+V Sbjct: 433 KCTIQDLATIMKDLGAYNAMNLDGGASTSLYANGKFLATPTRKISNALMV 482 Score = 81.6 bits (200), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 67/226 (29%), Positives = 108/226 (47%), Gaps = 26/226 (11%) Query: 37 VDKDNHAFIPLRFLNGFAGIQAGVSGQNGKEMTLSKNGTTVV-LVSGQASASVGGKSVKL 95 ++K+ F+P+R++ + G + +N ++ +NG++ V L G A V G L Sbjct: 45 LNKEGRIFVPIRYIAEYFGGEVEWDPEN--QIVNVRNGSSFVSLQIGFKFAGVNGAVKVL 102 Query: 96 SERPFSGNGTTYVPLSFISQTFGLQLVWNKTSASLTLAAGDDSATLPVLSGALISASSPA 155 PF NG TYVPL FIS+ G ++ W+ + + + G +S T V Sbjct: 103 DVAPFIYNGRTYVPLRFISEALGKEVRWDDQNRVVYIETGVESYTTTV------------ 150 Query: 156 AVSSRHTYTVGGRSFPVQMVTVSLLHPALKLDVVLAGNTVGKTEALGSIAKRSGAVAAIN 215 AVS+ T TV +V V L P +KL++V A + +G E S+ KR +AAIN Sbjct: 151 AVST-GTATV-------NVVKVFLNDPTIKLEIVNAQDQIGVLEPFESMVKRKNPLAAIN 202 Query: 216 GTFFDAYTDAAYKAPYGYIISRGKMLK-DSPADKRTVFAY--DNNL 258 GTFF + P ++ G++ +P + FA+ DN + Sbjct: 203 GTFFQVADTSLPMEPAANLVINGRIEHLGTPEKYASTFAFTQDNQV 248 >A6TUG6.1 A6TUG6_ALKMQ Copper amine oxidase domain protein Length = 491 Score = 106 bits (265), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 51/105 (48%), Positives = 76/105 (72%) Query: 277 VTGAIQAGPRLLVDGKVALNVAAEGFRDPKILTGGGSRSALGLTRDHKLILLTSGGATIP 336 VT AI AGP L+ +G + N +EGF + +ILT G RS +G+T+++KL++ T ++ Sbjct: 260 VTSAIGAGPTLIKNGVITANGLSEGFFEDEILTNRGQRSFIGVTKENKLVMGTVPSVSVK 319 Query: 337 QLAQIMKQAGAYQAMNLDGGASSGLFYSGKYLTSPGRLISNALVV 381 +LA+I K+ G YQA+NLDGGASSGL Y + + +PGRL+SNA+V+ Sbjct: 320 ELAEIAKELGLYQAINLDGGASSGLIYKDRMVHAPGRLLSNAIVI 364 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.132 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,069,967,382 Number of extensions: 87297989 Number of successful extensions: 244587 Number of sequences better than 1.0e-05: 183 Number of HSP's gapped: 244569 Number of HSP's successfully gapped: 188 Length of query: 384 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 247 Effective length of database: 1,770,017,148 Effective search space: 437194235556 Effective search space used: 437194235556 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)