BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0028.p (610 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KDQ0.1 B3KDQ0_9BACI Histidine kinase internal region 491 e-136 B3K4S2.1 B3K4S2_9BACI Histidine kinase internal region 441 e-122 B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transducti... 335 9e-90 A6CLU9.1 A6CLU9_9BACI Putative uncharacterized protein 322 1e-85 Q2BAB1.1 Q2BAB1_9BACI Putative uncharacterized protein 309 6e-82 >B3KDQ0.1 B3KDQ0_9BACI Histidine kinase internal region Length = 611 Score = 491 bits (1263), Expect = e-136, Method: Compositional matrix adjust. Identities = 261/612 (42%), Positives = 389/612 (63%), Gaps = 17/612 (2%) Query: 3 WNSIRTKLIVFLLLPTLVCILATMFISYSYTTKSLRTRAVDENTNLLYQGSKNISSFIQD 62 WNSIRTKLI F+++ T++ +M ISY TT SL+ RAV EN NLLYQG N+ S++++ Sbjct: 5 WNSIRTKLITFMIMATIIPTTISMIISYVMTTNSLKERAVVENMNLLYQGRLNLESYLEE 64 Query: 63 VNRLSLTIYSDSDFYRQLEAGYDDMSANIRIYSSLNYILTSMPDIFQVYLYRVKDSKATL 122 +NR SLT+YSD DF+R L +++++A+ R ++L I ++ QVYLY +ATL Sbjct: 65 MNRSSLTVYSDPDFFRSLYYSHENINASGRQSATLQSIQKAISGSRQVYLYVDGKREATL 124 Query: 123 LSHNATPKR-----WQGIPPYSDSRITDAYPLSIQSTHISNTYGLNSPIPQLTAEPVFTL 177 + + K + IP + + +Q H +TYG P + VFT+ Sbjct: 125 FAQDIARKTSEVNLYPEIPDLRNDTVV------LQPPHPLHTYGFQLAYPYEADQQVFTM 178 Query: 178 HRRIERIPSTEALGYLSIDVKLTAFTDIMNQLYEQDKENIYLVDDSGTLVYSHDEAALGK 237 +R IER+PSTE LG L+ID+ + + I QL++ D E +Y+ ++ G ++YS D+ LG+ Sbjct: 179 YRVIERVPSTERLGILAIDLDMDFLSRISGQLFQPDHEQLYIANEDGYIMYSGDDEMLGQ 238 Query: 238 PLKASWYDKPIAEKGLSQGYFEKDGAVFIYQKIESPGLNWTLVKQIPVSYLFREAKEAAR 297 ++A WY I + G +G+FE + +++Y I++ +WT++K+IP SY+ A +AA Sbjct: 239 QVQADWY-ASIKQSGKKEGHFEYNNKIYLYNNIKTSVSDWTMIKEIPSSYILSSADKAAF 297 Query: 298 XXXXXXXXXXXXXXXXXXXXSFRITAPIKQLTRYMNQVQTGNLEIDIRPAGKDEIGLVTE 357 S ITAPI++L M+QV++G + +DI KDEIG + Sbjct: 298 VNILLIGVSLILIIAATIWISVYITAPIRELVGLMSQVKSGRMTVDISSNRKDEIGALHR 357 Query: 358 RFRSMMDTINNLILREYRLELSNKTNELRALQSQINPHFLNNTLQIIGTLALELKVPQIY 417 RF SMMDTINNLIL+EY+L+L+N+TN+LRALQ+Q+NPHF+NN LQ IGTLALE + +IY Sbjct: 358 RFGSMMDTINNLILQEYKLKLANRTNQLRALQAQVNPHFMNNALQTIGTLALEHGMKRIY 417 Query: 418 ALLSALAKMMRYSMYNDEKIVTVQDELDHVKAYVELQKERFENKFTFRYDMEESLLKALM 477 +L+SALA+MMRYSMYN +K VT+ ELDH+K YVELQKERFEN+F FRYD++ES L+ L+ Sbjct: 418 SLISALARMMRYSMYNTDKPVTLATELDHIKDYVELQKERFENQFDFRYDVDESTLQVLI 477 Query: 478 PKMILQPIVENYFKHGFNLARTDGLIEIKAARLATGRMEITVRNNGSSIPAAKLEALREE 537 PKM++QP++EN+FKHG N D I + + RL+ ++ITV +NG+ + + L+E Sbjct: 478 PKMLVQPLIENFFKHGMNPLEQDNFIALTSRRLSASIVQITVEDNGNGMQEEPFQTLQEH 537 Query: 538 LQHPGRLDIDTLKETDSNDSKRDAPGARIGLPNVLARLRLVCGDSALLIVDNDKAGGVIV 597 L LD++ L+ +++ D+ G IGL N++ RLRL + ++N++ G V Sbjct: 538 LLRMEELDLEQLQVVSELETE-DSSG--IGLINIMTRLRLYYRGKSKFNIENNQPHGFRV 594 Query: 598 RLEIDIVVESET 609 L I+ VE ET Sbjct: 595 VLTIN--VEGET 604 >B3K4S2.1 B3K4S2_9BACI Histidine kinase internal region Length = 594 Score = 441 bits (1135), Expect = e-122, Method: Compositional matrix adjust. Identities = 242/601 (40%), Positives = 362/601 (60%), Gaps = 14/601 (2%) Query: 1 MKWNSIRTKLIVFLLLPTLVCILATMFISYSYTTKSLRTRAVDENTNLLYQGSKNISSFI 60 MK+ SI+T+LI F+L T + +L ++ I++++T +S++ + V+EN L+YQG+ N+ +++ Sbjct: 1 MKYRSIQTRLITFMLAVTTIPLLLSLIITFTHTRESVKEQTVNENVRLIYQGATNLMNYL 60 Query: 61 QDVNRLSLTIYSDSDFYRQLEAGYDDMSANIRIYSSLNYILTSMPDIFQVYLYRVKDSKA 120 + ++R SL++YSD F R L D+ +Y++L I T D+ Q+YL+ ++ Sbjct: 61 RGIDRASLSVYSDPHFLRNLALDPDNHRVVAELYATLQAIQTGTQDVHQIYLHNQLTGQS 120 Query: 121 TLLSHNATPKRWQGIPPYSDSRITDAYPLSIQSTHISNTYGLNSPIPQLTAEPVFTLHRR 180 T +S N P+R PY +I+ H ++YG + V T +R Sbjct: 121 TQISSNL-PRREFRQAPYRKIEEFGEGNTAIEPVHQVHSYGFPPRPADILDFEVITFYRS 179 Query: 181 IERIPSTEALGYLSIDVKLTAFTDIMNQLYEQDKENIYLVDDSGTLVYSHDEAALGKPLK 240 I +P+ + ++IDVKL + I +QLY + +E +YL+D SG+++Y D G+ L Sbjct: 180 ITNVPAPDQYALMAIDVKLDSILAICDQLYAKGEEALYLIDSSGSIIYGPDPQQRGQALD 239 Query: 241 ASWYDKPIAEKGLSQGYFEKDGAVFIYQKIESPGLNWTLVKQIPVSYLFREAKEAARXXX 300 IA+ +GY++ + A+ +Y+K++ P WTLVKQIP L++ + E Sbjct: 240 DPELMDVIAQA--ERGYYDGEDAMIVYEKLDLPYAPWTLVKQIPHQTLYKHSTELTSINA 297 Query: 301 XXXXXXXXXXXXXXXXXSFRITAPIKQLTRYMNQVQTGNLEIDIRPAGKDEIGLVTERFR 360 S RIT PIKQLT YMNQV+TG L+++I DEIG+++ RFR Sbjct: 298 IIAILALFIVIFGTLWISIRITKPIKQLTTYMNQVKTGRLDVNIDVTSPDEIGILSRRFR 357 Query: 361 SMMDTINNLILREYRLELSNKTNELRALQSQINPHFLNNTLQIIGTLALELKVPQIYALL 420 +MMDTINNLILREYRLE++NKTN+L+ALQ+QI+PHFL NTLQ IGTLAL+ VP+IY+LL Sbjct: 358 TMMDTINNLILREYRLEIANKTNQLKALQAQIDPHFLYNTLQSIGTLALQHNVPRIYSLL 417 Query: 421 SALAKMMRYSMYNDEKIVTVQDELDHVKAYVELQKERFENKFTFRYDMEESLLKALMPKM 480 S+LA MMRY+M N E VT+QDE++HV+ Y+ELQK+RF ++ +D++ L +PKM Sbjct: 418 SSLANMMRYNMRNSEGKVTLQDEINHVRLYLELQKQRFRDQLEIIWDVDPESLTTPVPKM 477 Query: 481 ILQPIVENYFKHGFNLARTDGLIEIKAARLATGRMEITVRNNGSSIPAAKLEALREELQH 540 ILQPIVENYFKHG N G I I GR+ + + NNG+SI A+L ++R +L+ Sbjct: 478 ILQPIVENYFKHGMNTHAGVGRISISTRIAEDGRLIVVIENNGASIEEAELASIRGKLE- 536 Query: 541 PGRLDIDTLKETDSNDSKRDAPGARIGLPNVLARLRLVCGDSALLIVDNDKAGGVIVRLE 600 D ND+ D+ IGL NV RL L + A L ++N + GV V L+ Sbjct: 537 ------TAFHHPDRNDAGEDS----IGLLNVYMRLNLYSNNHAELTIENAEPHGVKVTLD 586 Query: 601 I 601 I Sbjct: 587 I 587 >B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transduction histidine kinase Length = 610 Score = 335 bits (859), Expect = 9e-90, Method: Compositional matrix adjust. Identities = 218/617 (35%), Positives = 324/617 (52%), Gaps = 38/617 (6%) Query: 5 SIRTKLIVFLLLPTLVCILATMFISYSYTTKSLRTRAVDENTNLLYQGSKNISSFIQDVN 64 SI KL+ LL T++ I +M IS Y + +++ EN NLL G NI ++ +N Sbjct: 7 SINRKLMALLLAVTIIPITVSMIISNYYIKDKVTQQSIHENQNLLALGKNNILGYMDKIN 66 Query: 65 RLSLTIY----SDSDFYRQLEAGYD--------DMSANIRIYSSLNYILTSMPDIFQVYL 112 SL +Y + Y +E G D N++IY+ + I S I Q+ L Sbjct: 67 ENSLDVYLNINKSNSLYALIERGQSPNVNVPMFDEKNNLQIYAHMLNIYQSTNGIHQIQL 126 Query: 113 YRVKDSKATLLSHNATPKRWQGIP-PYSDSRITDAYPLSIQSTHISNTYGLNSPIPQLTA 171 ++ D K T L +R P + + P +++TH S Y L+ + Sbjct: 127 -QIGDGKLTYLMARGFFRRGINQPLEWPTEHGSSPKPF-VEATHTSAHYNLDWS-HAVKE 183 Query: 172 EPVFTLHRRIERIPSTEALGYLSIDVKLTAFTDIMNQLYEQDKENIYLVDDSGTLVYSHD 231 E VFTL R I R PS E +GYLS+DVK I QL +E +Y++D S V S + Sbjct: 184 ESVFTLRRPIIRTPSDEVIGYLSMDVKSDELNQICRQLTMSSEEQLYIIDRSRNFVCSVN 243 Query: 232 EAALGKPLKASWYDKPIA---EKGLSQGYFEKDGAVFIYQKIESPGLNWTLVKQIPVSYL 288 LK W D+ +A E G+ + + + IY + + ++W +VKQ+P SYL Sbjct: 244 GQEDQDRLK--WTDQVLASKQENGVIKWQDQSFSGIVIYDTLSTNYMDWVVVKQLPYSYL 301 Query: 289 FREAKEAARXXXXXXXXXXXXXXXXXXXXSFRITAPIKQLTRYMNQVQTGNLEIDIRPAG 348 + A S++ T PIK+L ++NQVQ+GN + + Sbjct: 302 YESATAIRTINTSVIAIFMVLAVIASFLVSYQFTKPIKRLIGHINQVQSGNFNVVVPVDR 361 Query: 349 KDEIGLVTERFRSMMDTINNLILREYRLELSNKTNELRALQSQINPHFLNNTLQIIGTLA 408 KDEIG++ RF +M+ TI +LI EYRLE++NKTN+LRA+Q+QINPHFL N LQ IGTLA Sbjct: 362 KDEIGILARRFNTMIQTIRDLINSEYRLEIANKTNQLRAMQAQINPHFLYNALQSIGTLA 421 Query: 409 LELKVPQIYALLSALAKMMRYSMYNDEKIVTVQDELDHVKAYVELQKERFENKFTFRYDM 468 L P++Y L++++AKMMRY+M E IV EL+H KAY+ELQ++RF + T YD+ Sbjct: 422 LHAGAPKVYTLITSIAKMMRYNMNTSESIVPFSMELNHAKAYLELQQQRFNEQLTVHYDI 481 Query: 469 EESLLKALMPKMILQPIVENYFKHGFNLARTDGLIEIKAARLATGR-MEITVRNNGSSIP 527 + + L +PKM+LQP+VENYFKHG+ + G++ + + G + I + +NGS + Sbjct: 482 DPASLSVQVPKMLLQPLVENYFKHGYETSGRSGVLRLFSEVTDDGSWLTIRIEDNGSGMD 541 Query: 528 AAKLEALREEL-QHPGRLDIDTLKETDSNDSKRDAPGARIGLPNVLARLRLVCGDSALLI 586 KL LR+ L + G L L+E S IG+ NV RL+L + A + Sbjct: 542 PDKLRELRQLLFRSTGAL----LEEQKS-----------IGISNVWMRLKLYYNEEAEMS 586 Query: 587 VDNDKAGGVIVRLEIDI 603 +D+ +GG V L I + Sbjct: 587 IDSSPSGGFTVTLRIPV 603 >A6CLU9.1 A6CLU9_9BACI Putative uncharacterized protein Length = 603 Score = 322 bits (824), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 215/625 (34%), Positives = 335/625 (53%), Gaps = 45/625 (7%) Query: 1 MKWNSIRTKLIVFLLLPTLVCILATMFISYSYTTKSLRTRAVDENTNLLYQGSKNISSFI 60 M NSIR KLIV L++ T++ +++ I+Y YT S+ V E++NLLYQG N+ ++I Sbjct: 1 MIKNSIRNKLIVLLMITTIIPFGSSIIITYLYTKNSIEEEVVQESSNLLYQGKINLENYI 60 Query: 61 QDVNRLSLTIYSDSDFYRQLEAGYDDMSANIRIYSSLNYILTSM-PDIFQVYLYRVKDSK 119 +++ L+L++Y++ DF + + S +Y+ + ++ Q +LY K K Sbjct: 61 NELSGLTLSLYNNPDFINYMRSP----------QSESDYLTIGLVKNVVQTFLYTEKTIK 110 Query: 120 ATLLSHNATPKRWQGIPPYSDSRITDAYPLSIQSTHIS---NTYGLN-SPI-PQLTAE-- 172 ++ A R +S + S Q + + Y LN +P PQ E Sbjct: 111 EVTITF-ADDDRVISATKHSTVVFSMREGASEQEALMKAARSPYNLNIAPAYPQQENERK 169 Query: 173 ---PVFTLHRRIERIPSTEALGYLSIDVKLTAFTDIMNQLYEQDKENIYLVDDSGTLVYS 229 + T+HR + IP+ E LGY+S+++ D+ LY D E YL+ G ++YS Sbjct: 170 RSKSIATIHRALINIPADEVLGYISLEILPDKILDLSKNLYNTDTEEFYLLTPEGEVIYS 229 Query: 230 HD-EAALGKPLKASWYDKPIAEKGLSQGYFE--KDG--AVFIYQKIESPGLNWTLVKQIP 284 D + +L K ++ + + I + + G E KD V +Y ++ W LVK++ Sbjct: 230 SDGDTSLNK--RSQEWIQEITDGNETSGTLEWQKDSFNGVMMYDRLSPSAGGWILVKRVS 287 Query: 285 VSYLFREAKEAARXXXXXXXXXXXXXXXXXXXXSFRITAPIKQLTRYMNQVQTGNLEIDI 344 + L+ A A+ SF+IT+PI+ L + QV+ G ++I+ Sbjct: 288 YANLYESAFSVAKINILFGFVGLSLVILSILFVSFKITSPIRVLLHNIQQVEKGEMKIES 347 Query: 345 RPAGKDEIGLVTERFRSMMDTINNLILREYRLELSNKTNELRALQSQINPHFLNNTLQII 404 + G DEIGL+ RF+ M+ IN+LI REY+LEL NKTN+L+ LQSQINPHFL N LQ I Sbjct: 348 QSFGTDEIGLLGSRFQQMIGRINHLINREYKLELENKTNQLKVLQSQINPHFLYNALQSI 407 Query: 405 GTLALELKVPQIYALLSALAKMMRYSMYNDEKIVTVQDELDHVKAYVELQKERFENKFTF 464 GT+AL+ KVPQIY L++ L+K+MRY M +E IV++ E+++ +AY+ LQKERF + + Sbjct: 408 GTIALKNKVPQIYTLITHLSKIMRYGMDMEEDIVSLNKEINYTRAYLLLQKERFGDHLDY 467 Query: 465 RYDMEESLLKALMPKMILQPIVENYFKHGFNLARTDGLIEIKAARLATGRMEITVRNNGS 524 ++EE L + +PKM+LQPI+ENYFKHGF++ G I + + ITV +NG+ Sbjct: 468 SIEVEEGLKEVKVPKMLLQPIIENYFKHGFDIREGIGRIRLNCFS-EHDELVITVEDNGA 526 Query: 525 SIPAAKLEALREELQHPGRLDIDTLKETDSNDSKRDAPGARIGLPNVLARLRLVCGDSAL 584 + A KL+ + E Q D T N S IGL NV RL+L A Sbjct: 527 GVTAQKLQEIYEHFQ------TDIKNTTGENTS--------IGLKNVFVRLKLYYNQQAS 572 Query: 585 LIVDNDKAGGVIVRLEIDIVVESET 609 L + N + GG V + + + +E +T Sbjct: 573 LELQNLE-GGFRVTMRLPVQMEGDT 596 >Q2BAB1.1 Q2BAB1_9BACI Putative uncharacterized protein Length = 599 Score = 309 bits (791), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 208/604 (34%), Positives = 326/604 (53%), Gaps = 29/604 (4%) Query: 4 NSIRTKLIVFLLLPTLVCILATMFISYSYTTKSLRTRAVDENTNLLYQGSKNISSFIQDV 63 NSIR KLIV LLL T++ ++ I+Y +T + L+ +AV+EN+ LLYQG N+ S++ ++ Sbjct: 4 NSIRNKLIVLLLLITIIPFGTSIIITYFHTKEFLKNQAVEENSKLLYQGKINLESYMNEL 63 Query: 64 NRLSLTIYSDSDFYRQLEAGYD-DMSANIRIYSSL-NYILTSMPDIFQVYLYRVKDSKAT 121 N L+L++Y++ F L + D D I I ++ IL + I +V + + + Sbjct: 64 NGLTLSLYNNPGFLNFLRSSKDEDNYLTIGIMKNVVQTILYAGDTINRVQIAFADEDRVI 123 Query: 122 LLSHNATPKRWQGIPPYSDSRITDAYPLSIQSTHISNTYGLNSPIPQLTAEPVFTLHRRI 181 S +T +G ++ +A+ + S+ S+ Y + + Q + + +HR Sbjct: 124 SASRRSTVVFMKG----RSAKSAEAFNRARDSS--SHMY-IEPLMEQTNSRNIMAVHRAF 176 Query: 182 ERIPSTEALGYLSIDVKLTAFTDIMNQLYEQDKENIYLVDDSGTLVYSHDEAALGKPLKA 241 IPS L Y+++++ ++ LY E Y+V G L+YS D+ A + Sbjct: 177 TNIPSDNVLAYITLEIAPDDIVNLSRNLYTPGSEEFYIVSQDGLLIYSSDKDAASGQVPE 236 Query: 242 SWYDKPIAEKGLSQGYFE--KD--GAVFIYQKIESPGLNWTLVKQIPVSYLFREAKEAAR 297 W D I G G E KD + IY+++E W LVK++P + L+ A A+ Sbjct: 237 KWVD-AIVSSGNKAGTLEWKKDDFSGMMIYEQMEESAGGWFLVKRVPDTTLYESAFSVAK 295 Query: 298 XXXXXXXXXXXXXXXXXXXXSFRITAPIKQLTRYMNQVQTGNLEIDIRPAGKDEIGLVTE 357 SFRIT+PI+ L R ++QV+ G++ ++ GKDEIG++ Sbjct: 296 INILFGIIGLTLVILATLFVSFRITSPIRVLLRSISQVERGDMNVEYDSFGKDEIGILGM 355 Query: 358 RFRSMMDTINNLILREYRLELSNKTNELRALQSQINPHFLNNTLQIIGTLALELKVPQIY 417 RF M++ IN+LI REY+LE+ NKTN+L+ LQSQINPHFL N LQ IGT+AL+ KVPQIY Sbjct: 356 RFNEMIEKINHLINREYKLEIENKTNQLKVLQSQINPHFLYNALQSIGTVALKNKVPQIY 415 Query: 418 ALLSALAKMMRYSMYNDEKIVTVQDELDHVKAYVELQKERFENKFTFRYDMEESLLKALM 477 L++ L+K+MRY M +E V + E+++ KA++ LQKERF KF +R D E + + Sbjct: 416 TLITHLSKIMRYGMDMEEDRVPLIKEINYTKAFLLLQKERFGEKFIYRIDAGEEVSSVKV 475 Query: 478 PKMILQPIVENYFKHGFNLARTDGLIEIKAARLATGRMEITVRNNGSSIPAAKLEALREE 537 PKM+LQP++ENYFKHGF G + I+ + +G + I + +NG +L Sbjct: 476 PKMLLQPVIENYFKHGFTPGEGTGELNIECNK-DSGFLCIDISDNGGGADDGRLG----- 529 Query: 538 LQHPGRLDIDTLKETDSNDSKRDAPGARIGLPNVLARLRLVCGDSALLIVDNDKAGGVIV 597 DI + ++K D+ IGL NV RL L G+ A+L + N G IV Sbjct: 530 -------DIWRCIKGGPLEAKGDS--TSIGLRNVYGRLMLYYGEEAILQLGNRGGKGFIV 580 Query: 598 RLEI 601 +++ Sbjct: 581 SMKL 584 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,302,757,194 Number of extensions: 133698704 Number of successful extensions: 403798 Number of sequences better than 1.0e-05: 2016 Number of HSP's gapped: 401455 Number of HSP's successfully gapped: 2025 Length of query: 610 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 468 Effective length of database: 1,722,912,073 Effective search space: 806322850164 Effective search space used: 806322850164 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)