BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0039.0008.p (574 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z8N5.1 C0Z8N5_BREBN Putative adenine deaminase EC=3.5.4.2 829 0.0 Q5WD17.1 ADEC2_BACSK Adenine deaminase 2 EC=3.5.4.2 692 0.0 A8RKA8.1 A8RKA8_9CLOT Putative uncharacterized protein 560 e-157 C3WFH0.1 C3WFH0_FUSMR Adenine deaminase 553 e-155 C0BWM4.1 C0BWM4_9CLOT Putative uncharacterized protein 545 e-153 >C0Z8N5.1 C0Z8N5_BREBN Putative adenine deaminase EC=3.5.4.2 Length = 569 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/568 (68%), Positives = 462/568 (81%) Query: 2 MITDQLILNAKVYNSYYKRFEPANVAVKDGRFLYVGTLGAETFTAKDTIQAEGQYMVPGL 61 M D LI + +V+NSY+K+F NVAV D RF Y+G ETF A + + +G+YM+PGL Sbjct: 1 MKVDLLIQDVQVFNSYFKKFIKGNVAVLDERFFYIGERSTETFEAAEIVDGQGRYMIPGL 60 Query: 62 IDIHLHIESTMITPETFSYGILRHGVTTIVPEPHEMANVFGVEGVHEMIRASRDCQVDMF 121 +DIHLHIESTM+TPETFS+G++++GVTTIVPEPHEMANVFG+EG+ EMIRASRDC VDM Sbjct: 61 VDIHLHIESTMVTPETFSFGLIQNGVTTIVPEPHEMANVFGIEGIKEMIRASRDCVVDML 120 Query: 122 YAIPSSVPATPLETTGGSIEIEDIDELMETERMICLGEVMNYVEVIRDPDGKSNRILQHV 181 YAIPSSVPAT +ETTGGS+EI D+DEL+ +E +ICLGE+MNYV++I+DPD K+NRIL+H+ Sbjct: 121 YAIPSSVPATSMETTGGSVEIADMDELLRSEEIICLGEIMNYVDIIKDPDCKTNRILEHI 180 Query: 182 RSRYPGLVIEGHTPKLLDLDLHRLIYAGIDSDHTHQSIEGLKARIAAGMFIEIQEKSMTP 241 R YP LVIEGH PKLLDLDLHR+IYAG+DSDHTHQ+ EG++ARIAAGMF+EIQEKSMT Sbjct: 181 RKTYPKLVIEGHVPKLLDLDLHRVIYAGVDSDHTHQTREGMEARIAAGMFLEIQEKSMTD 240 Query: 242 DVVDYLVRHAVSEHFCFVTDDVMTDSMVKTGHLDHLVRKAIAMGMAPEDAVYAATFTPAR 301 +V+DYL++ VSEHFCFVTDDVMTDS+V GHL+H+V+KAI MGM PE A+YA+TFTPAR Sbjct: 241 EVMDYLIKEDVSEHFCFVTDDVMTDSLVNRGHLNHIVKKAIQMGMQPERAIYASTFTPAR 300 Query: 302 RMKMNDRGVIAPNKTADYLLLSDLDSFAIEAVYKRGAQVYDRKQPLPQPETVPRFPEHFY 361 RM M DRG IAP K AD+LL+SDL IE VYK+G + YD K+ Q +FP HFY Sbjct: 301 RMNMTDRGAIAPGKIADFLLVSDLHELKIERVYKKGKKAYDVKEEYRQVVKEKQFPAHFY 360 Query: 362 RSVKLSSLTADDFTVRTGLPDGRYSSRVMMVNSISTFTEEKHAEAGVKNGLLQWQESGYG 421 S+KLS LT DF V +PD RY RVM+V + STFTE+ A V+ G L W+ES YG Sbjct: 361 ESIKLSPLTEQDFRVTVDVPDNRYPCRVMLVQNGSTFTEDHRGIAEVREGQLLWEESPYG 420 Query: 422 LVATFERYGKNGNRAYGLIGGDTIKRGAIATTYSHDNHNLLVVGHDPEDMAVAANAVIAG 481 L+A FERYG NGNR YGLI GDTIKRGA+AT+YSHDNHNLLVVGH+P DM VAAN VI Sbjct: 421 LIAVFERYGINGNRGYGLISGDTIKRGAVATSYSHDNHNLLVVGHNPHDMMVAANEVIRN 480 Query: 482 QGGFCVVLDGKVIASLALPVGGILTEAPLEETAERVLGLRTAMESLGYNHYNPIMSISTH 541 QGGF VV DGKVIASL LPVGGILTE PLE+TA+ V LR AMESLGYNHYNPIMSISTH Sbjct: 481 QGGFYVVEDGKVIASLHLPVGGILTEEPLEKTAKEVEQLRRAMESLGYNHYNPIMSISTH 540 Query: 542 SLPVSPALKITDHGLIDVGTGRVVPLLF 569 SLPVSPALK+TD GLIDV G++VPLL Sbjct: 541 SLPVSPALKLTDMGLIDVNDGKIVPLLL 568 >Q5WD17.1 ADEC2_BACSK Adenine deaminase 2 EC=3.5.4.2 Length = 573 Score = 692 bits (1785), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/568 (59%), Positives = 415/568 (73%), Gaps = 1/568 (0%) Query: 2 MITDQLILNAKVYNSYYKRFEPANVAVKDGRFLYVG-TLGAETFTAKDTIQAEGQYMVPG 60 M D L+ N +VYN+Y ++F ++VA+ +GRF+ +G + E+ A I +GQ M+PG Sbjct: 1 MHVDTLVKNVRVYNAYTQQFIASDVAIDEGRFVAIGHSDELESIQANTIIDGQGQQMIPG 60 Query: 61 LIDIHLHIESTMITPETFSYGILRHGVTTIVPEPHEMANVFGVEGVHEMIRASRDCQVDM 120 LIDIHLHIES+M+TPETFS+ +LR+GVTTIV EPHEMANVFG+EG+ MI AS C VDM Sbjct: 61 LIDIHLHIESSMVTPETFSWALLRNGVTTIVAEPHEMANVFGIEGIKAMIEASAACTVDM 120 Query: 121 FYAIPSSVPATPLETTGGSIEIEDIDELMETERMICLGEVMNYVEVIRDPDGKSNRILQH 180 YAIPSSVPAT LETTGG+I I ++DELM+TE + CLGE+MNYV+V+ PD K+N+IL+H Sbjct: 121 KYAIPSSVPATSLETTGGAIGIAEMDELMDTEDIQCLGEIMNYVDVLSKPDSKTNQILKH 180 Query: 181 VRSRYPGLVIEGHTPKLLDLDLHRLIYAGIDSDHTHQSIEGLKARIAAGMFIEIQEKSMT 240 R YP L IEGH PKL LDLH+++ AGI SDHTHQ+ EG++ARI AGMF+EIQEKSMT Sbjct: 181 FRRSYPALPIEGHVPKLTGLDLHQIVAAGIGSDHTHQTREGMEARIKAGMFLEIQEKSMT 240 Query: 241 PDVVDYLVRHAVSEHFCFVTDDVMTDSMVKTGHLDHLVRKAIAMGMAPEDAVYAATFTPA 300 DV+ YL+ + EHFCFVTDDVM DS+ K GHL+ L KA+A GM ED +YA T PA Sbjct: 241 DDVLSYLIENDTREHFCFVTDDVMADSLYKRGHLNVLANKALAAGMKFEDVIYACTMAPA 300 Query: 301 RRMKMNDRGVIAPNKTADYLLLSDLDSFAIEAVYKRGAQVYDRKQPLPQPETVPRFPEHF 360 +RMK+ DRG IAP K AD++LL++ F AVYK G +D P Q +FP HF Sbjct: 301 KRMKLEDRGAIAPGKIADFILLAEDGQFVFSAVYKDGMLAFDAASPYKQTPKPRQFPPHF 360 Query: 361 YRSVKLSSLTADDFTVRTGLPDGRYSSRVMMVNSISTFTEEKHAEAGVKNGLLQWQESGY 420 Y SVKL+ L +DF V DG + RVM V STFT+E V NGLLQWQ+S + Sbjct: 361 YESVKLAPLQEEDFHVVADRQDGIHVCRVMNVADGSTFTKETQERVPVANGLLQWQDSDF 420 Query: 421 GLVATFERYGKNGNRAYGLIGGDTIKRGAIATTYSHDNHNLLVVGHDPEDMAVAANAVIA 480 L+ATFERYGK G RA+GLI GD ++RGA+ATTYSHDNHNLLVVG + DM AANAVI Sbjct: 421 RLIATFERYGKTGGRAHGLIAGDILQRGAVATTYSHDNHNLLVVGANILDMVCAANAVIQ 480 Query: 481 GQGGFCVVLDGKVIASLALPVGGILTEAPLEETAERVLGLRTAMESLGYNHYNPIMSIST 540 QGG VV +G+V A L LPVGGIL+EAPL E A +V A+ +LGY HYNPIMS+ST Sbjct: 481 AQGGCAVVENGEVKAMLELPVGGILSEAPLAELAPKVESFVKALTALGYKHYNPIMSLST 540 Query: 541 HSLPVSPALKITDHGLIDVGTGRVVPLL 568 SLPVSPALKITD GLIDV G+VVPL Sbjct: 541 LSLPVSPALKITDFGLIDVNNGQVVPLF 568 >A8RKA8.1 A8RKA8_9CLOT Putative uncharacterized protein Length = 634 Score = 560 bits (1442), Expect = e-157, Method: Compositional matrix adjust. Identities = 290/577 (50%), Positives = 376/577 (65%), Gaps = 14/577 (2%) Query: 4 TDQLILNAKVYNSYYKRFEPANVAVKDGRFLYVGTLGAETFTAKDTIQAEGQYMVPGLID 63 D L+ A VYNSY+K+F PA+V+V G+FLY+ + + A +T+ AEG YMVPGLID Sbjct: 50 ADFLVRGAMVYNSYFKKFVPADVSVSGGKFLYIDSRRSGAVEADETVDAEGLYMVPGLID 109 Query: 64 IHLHIESTMITPETFSYGILRHGVTTIVPEPHEMANVFGVEGVHEMIRASRDCQVDMFYA 123 IH+HIES+M+TP F + GVTTIV EPHEMANV G++GV +MIRA + VD+FY Sbjct: 110 IHMHIESSMLTPGAFCRRLAECGVTTIVSEPHEMANVNGMQGVLDMIRAGENSPVDIFYG 169 Query: 124 IPSSVPATP--LETTGGSIEIEDIDELMETERMICLGEVMNYVEVIRDPDGKSNRILQHV 181 IPS VP+T LETTGG I E+++ L E + C+GEVMNY +IR+ + R L+ + Sbjct: 170 IPSCVPSTSPELETTGGIITCEEMEGLKENPWVACVGEVMNYRTIIRENQLEITRFLKQL 229 Query: 182 RSRYPGLVIEGHTPKLLDLDLHRLIYAGIDSDHTHQSIEGLKARIAAGMFIEIQEKSMTP 241 R + IEGH P LLDLDL + +Y GI+ DHT S+E L+ R A GMF+EIQEK + Sbjct: 230 REKDRIFPIEGHCPALLDLDLAKFLYLGINGDHTEHSLEELEQRFANGMFMEIQEKMLRR 289 Query: 242 DVVDYLVRHAVSEHFCFVTDDVMTDSMVKTGHLDHLVRKAIAMGMAPEDAVYAATFTPAR 301 +V+DY+ H + EHFCFVTDDVM D++ GHLD LVR+A+ +GM E AVY A+FTPA+ Sbjct: 290 EVLDYIREHGLEEHFCFVTDDVMADTLCIQGHLDALVRRAMELGMPAEQAVYNASFTPAK 349 Query: 302 RMKMNDRGVIAPNKTADYLLLSDLDSFAIEAVYKRGAQVY-----DRKQPLPQPETVP-- 354 RM + DRG IAP K AD+LLLSDLD+FA+ A YK G ++ +R+QP Q + P Sbjct: 350 RMNLLDRGAIAPGKIADFLLLSDLDTFAVSATYKNGKCIWRRGQDEREQP-AQEQHGPDR 408 Query: 355 ----RFPEHFYRSVKLSSLTADDFTVRTGLPDGRYSSRVMMVNSISTFTEEKHAEAGVKN 410 RFPE +Y S+ L F V G RVM + ST T+E E V++ Sbjct: 409 GQDMRFPEPYYHSIHLEFQEQSRFEVPMESDSGTVMVRVMEIQDGSTKTKEIIMEMPVRD 468 Query: 411 GLLQWQESGYGLVATFERYGKNGNRAYGLIGGDTIKRGAIATTYSHDNHNLLVVGHDPED 470 G L+W+ +G L A FERYGK YGL+ GD KRGA+AT+Y+HD HN+LV G +P D Sbjct: 469 GFLKWEGTGCLLAAVFERYGKGQAVGYGLVTGDCHKRGAVATSYAHDCHNILVAGANPAD 528 Query: 471 MAVAANAVIAGQGGFCVVLDGKVIASLALPVGGILTEAPLEETAERVLGLRTAMESLGYN 530 M +A N VI QGG G++ A L L VGGIL++ P +E + +R AM LGY Sbjct: 529 MKLALNRVIEMQGGMAAADGGRIQAELPLHVGGILSDRPAKEVGASLARVREAMTGLGYR 588 Query: 531 HYNPIMSISTHSLPVSPALKITDHGLIDVGTGRVVPL 567 HYNPIMS T +LP SPALK+TD GLIDV ++VPL Sbjct: 589 HYNPIMSFCTLTLPASPALKLTDKGLIDVKACKIVPL 625 >C3WFH0.1 C3WFH0_FUSMR Adenine deaminase Length = 571 Score = 553 bits (1426), Expect = e-155, Method: Compositional matrix adjust. Identities = 266/569 (46%), Positives = 371/569 (65%), Gaps = 2/569 (0%) Query: 2 MITDQLILNAKVYNSYYKRFEPANVAVKDGRFLYVGTLGAETFTAKDTIQAEGQYMVPGL 61 M D L+ N KV+NSY K+F+ NVA+ + +FLY+ F A TI + QYM+PG Sbjct: 1 MKVDLLVKNVKVFNSYLKKFKDGNVAILNNKFLYIDNNKNIEFEASSTIDGKNQYMIPGF 60 Query: 62 IDIHLHIESTMITPETFSYGILRHGVTTIVPEPHEMANVFGVEGVHEMIRASRDCQVDMF 121 IDIH+HIES+M+TP F + + ++GVTTIV EPHE+ANVFG +G+ MI A +F Sbjct: 61 IDIHMHIESSMMTPAPFCHHLSKNGVTTIVAEPHEIANVFGKKGIEAMIAAENSINTSIF 120 Query: 122 YAIPSSVPATP--LETTGGSIEIEDIDELMETERMICLGEVMNYVEVIRDPDGKSNRILQ 179 Y IPSSVP+T LETTG ++ E++ L ++IC+GE+MNY +VI D + ++ Sbjct: 121 YGIPSSVPSTSPDLETTGAILDFEEMKNLTSNPKVICIGEIMNYRKVIVDNSLDICKFIE 180 Query: 180 HVRSRYPGLVIEGHTPKLLDLDLHRLIYAGIDSDHTHQSIEGLKARIAAGMFIEIQEKSM 239 +V+ P IEGH PKLLDLDL + +Y GI+ DHT + E R GMF+E+Q KS+ Sbjct: 181 YVKKNKPQYAIEGHCPKLLDLDLAKFLYLGINGDHTEHTFEEFVQRFENGMFMELQAKSI 240 Query: 240 TPDVVDYLVRHAVSEHFCFVTDDVMTDSMVKTGHLDHLVRKAIAMGMAPEDAVYAATFTP 299 + ++++Y+ + + EHF FVTDD M D+ + GHL+ +++KAI G+ E+A+Y ATFTP Sbjct: 241 SSELINYIKENNLYEHFAFVTDDTMPDTFLHKGHLNVVIKKAIQAGINIENAIYCATFTP 300 Query: 300 ARRMKMNDRGVIAPNKTADYLLLSDLDSFAIEAVYKRGAQVYDRKQPLPQPETVPRFPEH 359 ARRM ++DRGVIAP K AD+LL+ +L + I + G +VY+ T +FPE Sbjct: 301 ARRMNLHDRGVIAPGKKADFLLIDNLKNLHITQTFIDGKEVYNINSEAKYIPTDYKFPEE 360 Query: 360 FYRSVKLSSLTADDFTVRTGLPDGRYSSRVMMVNSISTFTEEKHAEAGVKNGLLQWQESG 419 FY+SV++ + D F + + + R++ V ST T E + VKNG L W+ S Sbjct: 361 FYQSVRVEKINEDIFQIPVNNKENEVNCRIIKVIDGSTRTTEIIEKLNVKNGYLDWENSP 420 Query: 420 YGLVATFERYGKNGNRAYGLIGGDTIKRGAIATTYSHDNHNLLVVGHDPEDMAVAANAVI 479 Y L+A FER+GKNGN +GL+ GD IK GAIATTY+HD+HNL+V+G + +DM N +I Sbjct: 421 YMLIAVFERHGKNGNIGFGLVTGDCIKNGAIATTYAHDHHNLMVIGKNIKDMTKTINRII 480 Query: 480 AGQGGFCVVLDGKVIASLALPVGGILTEAPLEETAERVLGLRTAMESLGYNHYNPIMSIS 539 QGG C V + +++A + LPV GIL+E ++E + V LR M LGY HYNPIMS+ Sbjct: 481 ELQGGICCVENEEILAEVPLPVAGILSEKTVQELGKEVEILREKMSQLGYKHYNPIMSLC 540 Query: 540 THSLPVSPALKITDHGLIDVGTGRVVPLL 568 T SLPVSPALKITD GLIDV G++V L+ Sbjct: 541 TLSLPVSPALKITDKGLIDVNQGKIVNLI 569 >C0BWM4.1 C0BWM4_9CLOT Putative uncharacterized protein Length = 579 Score = 545 bits (1403), Expect = e-153, Method: Compositional matrix adjust. Identities = 276/577 (47%), Positives = 375/577 (64%), Gaps = 9/577 (1%) Query: 1 MMITDQLILNAKVYNSYYKRFEPANVAVKDGRFLYVGTLGAET----FTAKDTIQAEGQY 56 M D L+ NA+VYNSY K+FE A+V V GR YV A+ + I G Sbjct: 1 MEKVDLLVKNAEVYNSYLKKFETADVYVLGGRIYYVCRETADVREDMLEPEQVIDGTGYR 60 Query: 57 MVPGLIDIHLHIESTMITPETFSYGILRHGVTTIVPEPHEMANVFGVEGVHEMIRASRDC 116 M+PG +DIH+HIES+M+TP +F GVTT+V EPHE+ANV GV+G+HEMI ++D Sbjct: 61 MLPGFVDIHMHIESSMMTPVSFGRRAAGCGVTTLVSEPHEIANVAGVQGIHEMINGAKDA 120 Query: 117 QVDMFYAIPSSVPATP--LETTGGSIEIEDIDELMETERMICLGEVMNYVEVIRDPDGKS 174 +D++Y IPSSVP+T LETTGG I E++ LM + ++C+GEVMNY ++IR + + Sbjct: 121 PIDIYYGIPSSVPSTNSRLETTGGVIGFEEMKHLMGEDGVVCVGEVMNYRQIIRGDELEI 180 Query: 175 NRILQHVRSRYPGLVIEGHTPKLLDLDLHRLIYAGIDSDHTHQSIEGLKARIAAGMFIEI 234 + L H++ P VIEGH P L LDL + +Y GID DHT ++E LK R A GMF+E+ Sbjct: 181 TKFLDHLKEEDPQAVIEGHCPTLTGLDLAKFLYRGIDGDHTEHTLEELKDRFAGGMFVEL 240 Query: 235 QEKSMTPDVVDYLVRHAVSEHFCFVTDDVMTDSMVKTGHLDHLVRKAIAMGMAPEDAVYA 294 QEK + +V+D+++ + + EH CFVTDD M D +++ G L+++V+KA+A+G E+AVY Sbjct: 241 QEKMLRQEVLDHIITNRLYEHCCFVTDDTMADELMEHGQLNYVVQKAVALGFPLEEAVYC 300 Query: 295 ATFTPARRMKMNDRGVIAPNKTADYLLL--SDLDSFAIEAVYKRGAQVYDRKQPLPQPET 352 A++TPARRM + DRG IAP K AD+ L+ + F E V+K G +++ R + Q Sbjct: 301 ASYTPARRMNLRDRGAIAPGKKADFQLIRTEECSGFQPEYVFKDGKEIFCRGEVSDQAGG 360 Query: 353 VPRFPEHFYRSVKLSSLTADDFTVRTGLPDGRYSSRVMMVNSISTFTEEKHAEAGVKNGL 412 FPE FY S+ L +T D F GL R + RV+ V T T E H E VK+G Sbjct: 361 -HMFPESFYDSLHLPDITCDKFVPAKGLKGERAAVRVIQVQDGCTQTSEIHREMKVKDGC 419 Query: 413 LQWQESGYGLVATFERYGKNGNRAYGLIGGDTIKRGAIATTYSHDNHNLLVVGHDPEDMA 472 LQW+ESG L A FER+GKNGN YG + GD I++GA ATTY HD+HNLLV+G + EDM Sbjct: 420 LQWEESGCMLAAVFERHGKNGNIGYGFVTGDCIRKGAAATTYFHDHHNLLVIGSNVEDML 479 Query: 473 VAANAVIAGQGGFCVVLDGKVIASLALPVGGILTEAPLEETAERVLGLRTAMESLGYNHY 532 AA+ +I +GG C +GK+ A LALPV GIL+E P +E + G+R ++ +LGY HY Sbjct: 480 AAAHRIIELKGGICTAENGKITAELALPVAGILSEEPADEIGRMLSGVRKSLITLGYRHY 539 Query: 533 NPIMSISTHSLPVSPALKITDHGLIDVGTGRVVPLLF 569 NPIMS+ T LPVSPALK+TD GL+DV VPL+ Sbjct: 540 NPIMSLCTLGLPVSPALKLTDCGLVDVVRAETVPLIL 576 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.137 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,562,265,866 Number of extensions: 156328711 Number of successful extensions: 384895 Number of sequences better than 1.0e-05: 539 Number of HSP's gapped: 383346 Number of HSP's successfully gapped: 600 Length of query: 574 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 433 Effective length of database: 1,732,333,088 Effective search space: 750100227104 Effective search space used: 750100227104 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)