BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0038.0008.p (252 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIT7.1 B3KIT7_9BACI 2-oxoglutarate dehydrogenase, E2 subunit, ... 388 e-106 B4AKX4.1 B4AKX4_BACPU Dihydrolipoyllysine-residue succinyltransf... 370 e-101 A8FE65.1 A8FE65_BACP2 Dihydrolipoyllysine-residue succinyltransf... 369 e-101 Q65IH5.1 Q65IH5_BACLD OdhB 369 e-100 Q9KAT2.1 Q9KAT2_BACHD Dihydrolipoamide succinyltransferase 367 e-100 >B3KIT7.1 B3KIT7_9BACI 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Length = 424 Score = 388 bits (996), Expect = e-106, Method: Compositional matrix adjust. Identities = 188/223 (84%), Positives = 203/223 (91%) Query: 17 EDGKAVERKRMSRRRLTIASRLVEAQQTAAMLTTFNEVDMTAILDLRKRRKDAFKEKHDV 76 E GK VER RMSRRR TIA+RLVEAQ TAAMLTTFNEVDMTAILD+RKRRK AF+EKHDV Sbjct: 189 EYGKPVERTRMSRRRQTIANRLVEAQHTAAMLTTFNEVDMTAILDVRKRRKQAFQEKHDV 248 Query: 77 GLGFMSFFTKAVIGALKAYPLLNAEIDGEDLLIKKYYDIGIAVSAKEGLVVPVVRDADRL 136 GLGFMSFFTKAV+GALK +P LNAEIDG+D+++KK+YDIGIAVSAKEGLVVPVVRDADRL Sbjct: 249 GLGFMSFFTKAVVGALKRFPHLNAEIDGDDIVVKKFYDIGIAVSAKEGLVVPVVRDADRL 308 Query: 137 SFPEIERRIGELASKARANTLSLPELQGGTFTITNGGVFGSLMSTPILNTPQVGILGMHK 196 F EIE+ IG LA+KAR N LSL ELQGGTFTITNGGVFGSL+STPILNTPQVGILGMHK Sbjct: 309 GFAEIEKEIGNLAAKARNNALSLSELQGGTFTITNGGVFGSLLSTPILNTPQVGILGMHK 368 Query: 197 IQLRPIALDEERTVNRPMMYIALSYDHRIVDGSEAVSFLVKVK 239 IQLRP+A+D ER NRPMMYIALSYDHRIVDGSEAV FLV VK Sbjct: 369 IQLRPVAIDAERMENRPMMYIALSYDHRIVDGSEAVRFLVTVK 411 >B4AKX4.1 B4AKX4_BACPU Dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (Succinyl-transferring) complex EC=2.3.1.61 Length = 418 Score = 370 bits (949), Expect = e-101, Method: Compositional matrix adjust. Identities = 176/224 (78%), Positives = 199/224 (88%) Query: 16 QEDGKAVERKRMSRRRLTIASRLVEAQQTAAMLTTFNEVDMTAILDLRKRRKDAFKEKHD 75 ++ GK +ER+RMSRRR TIA RLVE QQTAAMLTTFNEVDMTA++DLRKRRKDAF E++D Sbjct: 182 EQPGKPIERERMSRRRQTIAKRLVEVQQTAAMLTTFNEVDMTAVMDLRKRRKDAFLEQND 241 Query: 76 VGLGFMSFFTKAVIGALKAYPLLNAEIDGEDLLIKKYYDIGIAVSAKEGLVVPVVRDADR 135 V LGFMSFFTKAV+ ALK YPLLNAEI G++L++KK+YDIGIAV+A EGLVVPVVRDADR Sbjct: 242 VKLGFMSFFTKAVVAALKKYPLLNAEIQGDELVLKKFYDIGIAVAANEGLVVPVVRDADR 301 Query: 136 LSFPEIERRIGELASKARANTLSLPELQGGTFTITNGGVFGSLMSTPILNTPQVGILGMH 195 LSF IE+ IG LA KAR N LSL ELQGG+FTITNGG FGSL+STPILN+PQVGILGMH Sbjct: 302 LSFAGIEKEIGHLAKKARDNKLSLNELQGGSFTITNGGTFGSLLSTPILNSPQVGILGMH 361 Query: 196 KIQLRPIALDEERTVNRPMMYIALSYDHRIVDGSEAVSFLVKVK 239 KIQLRP+A+DEER NRPMMY+ALSYDHRIVDG EAV FLV +K Sbjct: 362 KIQLRPVAIDEERFENRPMMYLALSYDHRIVDGKEAVGFLVTIK 405 >A8FE65.1 A8FE65_BACP2 Dihydrolipoyllysine-residue succinyltransferase EC=2.3.1.61 Length = 418 Score = 369 bits (948), Expect = e-101, Method: Compositional matrix adjust. Identities = 177/224 (79%), Positives = 199/224 (88%) Query: 16 QEDGKAVERKRMSRRRLTIASRLVEAQQTAAMLTTFNEVDMTAILDLRKRRKDAFKEKHD 75 ++ GK VER+RMSRRR TIA RLVE QQTAAMLTTFNEVDMTA++DLRKRRKDAF E++D Sbjct: 182 EQAGKPVERERMSRRRQTIAKRLVEVQQTAAMLTTFNEVDMTAVMDLRKRRKDAFLEQND 241 Query: 76 VGLGFMSFFTKAVIGALKAYPLLNAEIDGEDLLIKKYYDIGIAVSAKEGLVVPVVRDADR 135 V LGFMSFFTKAV+ ALK YPLLNAEI G++L++KK+YDIGIAV+A EGLVVPVVRDADR Sbjct: 242 VKLGFMSFFTKAVVAALKKYPLLNAEIQGDELVLKKFYDIGIAVAANEGLVVPVVRDADR 301 Query: 136 LSFPEIERRIGELASKARANTLSLPELQGGTFTITNGGVFGSLMSTPILNTPQVGILGMH 195 LSF IE+ IG LA KAR N LSL ELQGG+FTITNGG FGSL+STPILN+PQVGILGMH Sbjct: 302 LSFAGIEKEIGHLAKKARDNKLSLNELQGGSFTITNGGTFGSLLSTPILNSPQVGILGMH 361 Query: 196 KIQLRPIALDEERTVNRPMMYIALSYDHRIVDGSEAVSFLVKVK 239 KIQLRP+A+DEER NRPMMY+ALSYDHRIVDG EAV FLV +K Sbjct: 362 KIQLRPVAIDEERFENRPMMYLALSYDHRIVDGKEAVGFLVTIK 405 >Q65IH5.1 Q65IH5_BACLD OdhB Length = 426 Score = 369 bits (946), Expect = e-100, Method: Compositional matrix adjust. Identities = 176/221 (79%), Positives = 196/221 (88%) Query: 19 GKAVERKRMSRRRLTIASRLVEAQQTAAMLTTFNEVDMTAILDLRKRRKDAFKEKHDVGL 78 GK VER+RMSRRR TIA RLVE Q TAAMLTTFNEVDMTA+++LRKRRKD F E+HDV L Sbjct: 193 GKPVERQRMSRRRQTIAKRLVEVQHTAAMLTTFNEVDMTAVMNLRKRRKDQFLEQHDVKL 252 Query: 79 GFMSFFTKAVIGALKAYPLLNAEIDGEDLLIKKYYDIGIAVSAKEGLVVPVVRDADRLSF 138 GFMSFFTKAV+ ALK YPLLNAEI G++L+IKK+YDIGIAV+A +GLVVPVVRDADR +F Sbjct: 253 GFMSFFTKAVVAALKKYPLLNAEIQGDELVIKKFYDIGIAVAAPDGLVVPVVRDADRKTF 312 Query: 139 PEIERRIGELASKARANTLSLPELQGGTFTITNGGVFGSLMSTPILNTPQVGILGMHKIQ 198 +IER IGELA KAR N LSL ELQGG+FTITNGG FGSL+STPILN+PQVGILGMHKIQ Sbjct: 313 ADIERDIGELAKKARNNKLSLNELQGGSFTITNGGTFGSLLSTPILNSPQVGILGMHKIQ 372 Query: 199 LRPIALDEERTVNRPMMYIALSYDHRIVDGSEAVSFLVKVK 239 LRP+A+DEER NRPMMYIALSYDHRIVDG EAV FLV +K Sbjct: 373 LRPVAIDEERFENRPMMYIALSYDHRIVDGKEAVGFLVTIK 413 >Q9KAT2.1 Q9KAT2_BACHD Dihydrolipoamide succinyltransferase Length = 411 Score = 367 bits (941), Expect = e-100, Method: Compositional matrix adjust. Identities = 179/221 (80%), Positives = 192/221 (86%) Query: 19 GKAVERKRMSRRRLTIASRLVEAQQTAAMLTTFNEVDMTAILDLRKRRKDAFKEKHDVGL 78 GK VER +MSRRR TIA RLVEAQQTAAMLTTFNEVDM+A+++LRKRRKD F EKHDV L Sbjct: 178 GKPVERIKMSRRRQTIAKRLVEAQQTAAMLTTFNEVDMSAVMELRKRRKDQFFEKHDVKL 237 Query: 79 GFMSFFTKAVIGALKAYPLLNAEIDGEDLLIKKYYDIGIAVSAKEGLVVPVVRDADRLSF 138 GFMSFFTKAVIGALK +PLLNAEI G+++L+KKYYDIGIAVS EGLVVPVVRDADRL F Sbjct: 238 GFMSFFTKAVIGALKEFPLLNAEIQGDEILLKKYYDIGIAVSTDEGLVVPVVRDADRLGF 297 Query: 139 PEIERRIGELASKARANTLSLPELQGGTFTITNGGVFGSLMSTPILNTPQVGILGMHKIQ 198 IER I L KAR N LSL ELQGGTFTITNGGVFGSL STPILN PQVGILGMHKIQ Sbjct: 298 AGIEREIMHLGKKARENKLSLSELQGGTFTITNGGVFGSLWSTPILNAPQVGILGMHKIQ 357 Query: 199 LRPIALDEERTVNRPMMYIALSYDHRIVDGSEAVSFLVKVK 239 RP+A+DEE NRPMMYIALSYDHRIVDG EAVSFLV+VK Sbjct: 358 WRPVAIDEENFENRPMMYIALSYDHRIVDGKEAVSFLVRVK 398 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,219,462,419 Number of extensions: 48855532 Number of successful extensions: 127647 Number of sequences better than 1.0e-05: 3566 Number of HSP's gapped: 122829 Number of HSP's successfully gapped: 3566 Length of query: 252 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 120 Effective length of database: 1,817,122,223 Effective search space: 218054666760 Effective search space used: 218054666760 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 129 (54.3 bits)