BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0009.p (389 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q98HN4.1 Q98HN4_RHILO Mll2789 protein 516 e-144 C1XRL5.1 C1XRL5_9DEIN Biotin carboxylase 364 8e-99 C1XMK0.1 C1XMK0_MEIRU Carbamoylphosphate synthase large subunit 351 7e-95 C0Q9M6.1 C0Q9M6_DESAH Putative carbamoylphosphate synthase, larg... 343 2e-92 A7NRD0.1 A7NRD0_ROSCS Biotin carboxylase-like protein 341 9e-92 >Q98HN4.1 Q98HN4_RHILO Mll2789 protein Length = 446 Score = 516 bits (1329), Expect = e-144, Method: Compositional matrix adjust. Identities = 238/389 (61%), Positives = 303/389 (77%), Gaps = 1/389 (0%) Query: 1 VNFIFFSPHFPRNSADFCSQLHQQGATVLGIGDAEYDQLEDKLKSALTEYYKVSSLENHG 60 +NF+FFSPHFP N ADFC +L + GATVLGIGDA YD L+ +LK+AL+EYY+V+ +E++ Sbjct: 59 MNFVFFSPHFPANGADFCDRLKKAGATVLGIGDAPYDVLDGRLKAALSEYYRVADMEDYD 118 Query: 61 EILRAVGYFTHQYGKIDRFESLNEYWLEQDAAIRTDFNIYGTKTDFVYNLKQKSKMKEFF 120 + RA+G+F H++G+IDRFESLNE+WLE +A IRTDFNIYGTK DFV NLK+KS+M+ FF Sbjct: 119 PVFRAMGHFIHKWGRIDRFESLNEHWLELEANIRTDFNIYGTKLDFVKNLKRKSRMRAFF 178 Query: 121 RKSGVSTVQFSTGTTRDSVQDFIRSTGFPLVVKPDLGSGASMTYKINNEAELQQFFDTKP 180 RKSGV T+ + R FIR G+P+VVKPD GSGAS T+KI+N EL QFF KP Sbjct: 179 RKSGVETIAQRKCSDRAGAMTFIRRVGYPVVVKPDSGSGASNTFKISNTGELDQFFRDKP 238 Query: 181 DDVAFIIEEFIDGVILTYDGLVDIEGNVRFAASHLFENSVMDVVNTDNHLYYFCLKDVSP 240 +DV F++E+FI+G+++TYDGLV+ +G V AASH ++ SVM+VVN D H+ Y C + P Sbjct: 239 EDVTFVMEQFIEGLVVTYDGLVNRDGEVVLAASHRYDQSVMEVVNKDRHMSYTCFPHIRP 298 Query: 241 EVELAGRNILKAFDIKERFFHIELFKSNMDGRIIALEVNMRPPGAWMTDAINFSYDVDVY 300 VE AGR ILKAFD++ERFFHIELF++ D RIIALEVNMRPPGAWMTDAIN+++D+DVY Sbjct: 299 AVEEAGRKILKAFDVRERFFHIELFETR-DDRIIALEVNMRPPGAWMTDAINYTFDIDVY 357 Query: 301 REWARMVVHNEVSGPFEGKYYTGYASRKQHKHYSHSHEDIYRMYGDKIVNYAGIEEVFSR 360 WA MVV + GP+EGKY+T YASRK+H HY HSHED+ + DKIV++ IEEVFSR Sbjct: 358 AAWADMVVKDAAGGPYEGKYFTAYASRKRHLHYLHSHEDVLAAHRDKIVHHQAIEEVFSR 417 Query: 361 AMGNSAYQFRSADLADVRDIVNYIQQEEG 389 AMGN AYQ RS D A +R+ V Y+ E+ Sbjct: 418 AMGNYAYQMRSKDQAALREAVAYVHAEKA 446 >C1XRL5.1 C1XRL5_9DEIN Biotin carboxylase Length = 388 Score = 364 bits (935), Expect = 8e-99, Method: Compositional matrix adjust. Identities = 174/388 (44%), Positives = 257/388 (66%), Gaps = 3/388 (0%) Query: 1 VNFIFFSPHFPRNSADFCSQLHQQGATVLGIGDAEYDQLEDKLKSALTEYYKVSSLENHG 60 +N +F SPHFP N +FC +L + GA VLG+ DA Y+ L +LK+ALTEYY+VS + ++ Sbjct: 1 MNVVFLSPHFPPNFYNFCVRLREAGANVLGLADAPYESLRPELKAALTEYYRVSDMHHYD 60 Query: 61 EILRAVGYFTHQYGKIDRFESLNEYWLEQDAAIRTDFNIYGTKTDFVYNLKQKSKMKEFF 120 E+LRA+GYFTH+YGKIDR +SL+EYWLE +AA+RTDFNIYG + D + +K+KS+MK+ F Sbjct: 61 ELLRALGYFTHRYGKIDRLDSLSEYWLETEAALRTDFNIYGIRQDSISKIKRKSEMKKLF 120 Query: 121 RKSGVSTVQFSTGTTRDSVQDFIRSTGFPLVVKPDLGSGASMTYKINNEAELQQFFDTKP 180 +++G+ + T + + F++ G+P+V KPD+G GA+ TYKI +E ELQ + K Sbjct: 121 QQAGLRVARGRVCHTPEEARAFVKEVGYPVVAKPDVGVGAAKTYKIIDEWELQHYLSDK- 179 Query: 181 DDVAFIIEEFIDGVILTYDGLVDIEGNVRFAASHLFENSVMDVVNTDNHLYYFCLKDVSP 240 V +I+EEFI G I+TYDGL D EG V +A+S ++ VM+ V D+ +YY+ +++ Sbjct: 180 LPVEYILEEFIPGTIVTYDGLADREGRVVYASSMIYSKGVMETVLEDSDIYYYMPREIPR 239 Query: 241 EVELAGRNILKAFDIKERFFHIELFKSNMDGRIIALEVNMRPPGAWMTDAINFSYDVDVY 300 +++ AGR I + F +KER FH E F+ DG ++ALEVNMRPPG D N++ D+D Y Sbjct: 240 DLDEAGRRITEVFGVKERPFHYEFFRLE-DGGLVALEVNMRPPGGLTVDMFNYAGDLDFY 298 Query: 301 REWARMVVHNEVSGPFEGK-YYTGYASRKQHKHYSHSHEDIYRMYGDKIVNYAGIEEVFS 359 + WA MVV E P + YY Y RK ++HY HE + +G IV++ I +F+ Sbjct: 299 KMWAEMVVKGETHVPPPPRPYYCAYVGRKYNQHYLWPHEAVLHEFGPLIVHHEEISGIFA 358 Query: 360 RAMGNSAYQFRSADLADVRDIVNYIQQE 387 +A+GN Y R +LA + + IQ++ Sbjct: 359 QAIGNYGYILRHPELAPLLEACEQIQRK 386 >C1XMK0.1 C1XMK0_MEIRU Carbamoylphosphate synthase large subunit Length = 386 Score = 351 bits (900), Expect = 7e-95, Method: Compositional matrix adjust. Identities = 170/386 (44%), Positives = 248/386 (64%), Gaps = 2/386 (0%) Query: 1 VNFIFFSPHFPRNSADFCSQLHQQGATVLGIGDAEYDQLEDKLKSALTEYYKVSSLENHG 60 +N +F SPHFP N FC +L + G VLG+ DAEYD L +LK ALTEYY+VS + N+ Sbjct: 1 MNVVFLSPHFPPNFWPFCVRLREAGHNVLGLADAEYDALRPELKQALTEYYRVSDMHNYD 60 Query: 61 EILRAVGYFTHQYGKIDRFESLNEYWLEQDAAIRTDFNIYGTKTDFVYNLKQKSKMKEFF 120 E+LRA+GYFTH+YGKIDR +S++EYWLE +A +R DFNI+G + + +K+KS MK +F Sbjct: 61 ELLRALGYFTHRYGKIDRLDSMSEYWLETEARLREDFNIFGLRPQDMDRVKRKSVMKRYF 120 Query: 121 RKSGVSTVQFSTGTTRDSVQDFIRSTGFPLVVKPDLGSGASMTYKINNEAELQQFFDTKP 180 +++G+ + + QDF+ G+P+V KPD+G GA+ TYKI N+AEL + TKP Sbjct: 121 QQAGLRVARGRICRSAVEAQDFVEEVGYPVVAKPDIGVGAAKTYKITNDAELMDYIATKP 180 Query: 181 DDVAFIIEEFIDGVILTYDGLVDIEGNVRFAASHLFENSVMDVVNTDNHLYYFCLKDVSP 240 V +I+EEFI G I+TYDGL DI+GNV F +S + VM+VVN D +YY+ ++++ Sbjct: 181 -PVDYIMEEFIPGKIITYDGLTDIQGNVVFDSSLEYSKGVMEVVNQDTDIYYYMVREIPE 239 Query: 241 EVELAGRNILKAFDIKERFFHIELFKSNMDGRIIALEVNMRPPGAWMTDAINFSYDVDVY 300 ++ AGR +++AF+++E F F DG ++ALEVNMRPPG D N++ D+D++ Sbjct: 240 DLREAGRRVVQAFNVRE-RFFHFEFFRLEDGGLVALEVNMRPPGGLSIDMFNYANDMDIF 298 Query: 301 REWARMVVHNEVSGPFEGKYYTGYASRKQHKHYSHSHEDIYRMYGDKIVNYAGIEEVFSR 360 +EW ++ H VS + Y+ Y RK H HY SHE + +G I ++ I +F+ Sbjct: 299 KEWVNVLTHGRVSQQAQHPYFCTYVGRKDHIHYKRSHEQVLAEFGPLIAHHERISGIFAG 358 Query: 361 AMGNSAYQFRSADLADVRDIVNYIQQ 386 A+GN Y R DL + IQ+ Sbjct: 359 AIGNYGYILRHPDLPTLLQAAQAIQE 384 >C0Q9M6.1 C0Q9M6_DESAH Putative carbamoylphosphate synthase, large subunit EC=4.1.1.21 Length = 385 Score = 343 bits (879), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 168/386 (43%), Positives = 234/386 (60%), Gaps = 2/386 (0%) Query: 1 VNFIFFSPHFPRNSADFCSQLHQQGATVLGIGDAEYDQLEDKLKSALTEYYKVSSLENHG 60 +N ++ P FP N + FCS+L G TVLGIGD + L ++ +L YY V L N+ Sbjct: 1 MNLVYICPQFPPNFSPFCSRLKALGVTVLGIGDGPAESLSQEISDSLAAYYMVDDLHNYD 60 Query: 61 EILRAVGYFTHQYGKIDRFESLNEYWLEQDAAIRTDFNIYGTKTDFVYNLKQKSKMKEFF 120 +++A GYF HQYGKIDR ES NEYWL DA +R DFNI G K + +++KS MKE F Sbjct: 61 SLVKACGYFIHQYGKIDRLESHNEYWLATDAGLRLDFNIQGLKPADMQFIRRKSGMKEVF 120 Query: 121 RKSGVSTVQFSTGTTRDSVQDFIRSTGFPLVVKPDLGSGASMTYKINNEAELQQFFDTKP 180 R++G+ T + ++ TG+P+V KPD G GA T+KINN+ EL F + KP Sbjct: 121 RRAGIKVAPGKVVHTLADAEGVVKETGYPVVAKPDDGVGALDTFKINNKKELLSFIEKKP 180 Query: 181 DDVAFIIEEFIDGVILTYDGLVDIEGNVRFAASHLFENSVMDVVNTDNHLYYFCLKDVSP 240 D +I+E F+ G I ++DGL D +GN+ F +H F +MDVVN +HL+Y+ L+ + Sbjct: 181 DH-DYIMEGFVKGTIFSFDGLTDRDGNIIFCTAHTFSQGIMDVVNNGDHLFYYSLRSIPK 239 Query: 241 EVELAGRNILKAFDIKERFFHIELFKSNMDGRIIALEVNMRPPGAWMTDAINFSYDVDVY 300 E+E GR + AF +KERFFHIE FK+ +ALEVNMRPPG + TD N++ D+DVY Sbjct: 240 ELEAVGRKAVSAFTVKERFFHIEFFKTG-PTDYVALEVNMRPPGGYTTDMFNYASDIDVY 298 Query: 301 REWARMVVHNEVSGPFEGKYYTGYASRKQHKHYSHSHEDIYRMYGDKIVNYAGIEEVFSR 360 + WA +V + KY+ YASRK +Y HSHE+I YG I+ + VFS Sbjct: 299 KLWAEVVNGRTEPLDYHRKYHCCYASRKNRFNYVHSHEEIMDHYGSCILEVPSVPGVFST 358 Query: 361 AMGNSAYQFRSADLADVRDIVNYIQQ 386 A+G+ Y FR D+ +I +I + Sbjct: 359 ALGDIGYIFRVEHERDLFEITAFIHE 384 >A7NRD0.1 A7NRD0_ROSCS Biotin carboxylase-like protein Length = 389 Score = 341 bits (874), Expect = 9e-92, Method: Compositional matrix adjust. Identities = 176/386 (45%), Positives = 252/386 (65%), Gaps = 3/386 (0%) Query: 1 VNFIFFSPHFPRNSADFCSQLHQQGATVLGIGDAEYDQLEDKLKSALTEYYKVSSLENHG 60 +N +F SPHFP N FC +L GA VLG+ D Y+ L L++ALTEYY+VS L ++ Sbjct: 3 MNIVFLSPHFPPNWYLFCVRLRNLGANVLGVADEPYELLHPDLRTALTEYYRVSDLHHYD 62 Query: 61 EILRAVGYFTHQYGKIDRFESLNEYWLEQDAAIRTDFNIYGTKTDFVYNLKQKSKMKEFF 120 E+LRA+GYFTH+YGKI R +SLNEYWLE +A +RTDFNI G K + +K+KS+MK F Sbjct: 63 EVLRALGYFTHRYGKIQRVDSLNEYWLETEARLRTDFNIEGPKITDLPGIKRKSEMKRLF 122 Query: 121 RKSGVSTVQFSTGTTRDSVQDFIRSTGFPLVVKPDLGSGASMTYKINNEAELQQFFDTKP 180 ++ V + + V+ F G+PLV KPD+G GA+ TYKI ++AEL F +P Sbjct: 123 TRAQVDVARGILAHSPAQVRAFAVEVGYPLVAKPDVGVGANHTYKITSDAELDAFLSRQP 182 Query: 181 DDVAFIIEEFIDGVILTYDGLVDIEGNVRFAASHLFENSVMDVVNTDNHLYYFCLKDVSP 240 + F+IEE++ GVI T+DGL D +G F S + N V++VVN D+ +YY +D+ P Sbjct: 183 E--GFLIEEYVHGVIQTFDGLADRDGEPVFFTSMQYSNGVLEVVNNDDDIYYLTERDIPP 240 Query: 241 EVELAGRNILKAFDIKERFFHIELFKSNMDGRIIALEVNMRPPGAWMTDAINFSYDVDVY 300 ++E AGR ILK F+++ERFFH E F++ GR++ALEVNMRPPG D N++ ++D+Y Sbjct: 241 DLEQAGRRILKIFNVRERFFHFEFFRTP-KGRLVALEVNMRPPGGLSIDMFNYAGNIDLY 299 Query: 301 REWARMVVHNEVSGPFEGKYYTGYASRKQHKHYSHSHEDIYRMYGDKIVNYAGIEEVFSR 360 WA +++++ VS P Y+ YA RK + Y+ +HE++ +GD IV++ + +F R Sbjct: 300 NAWANVLINHRVSIPPTRLYHVCYAGRKPFRSYALTHEEVLIRFGDCIVHHQPMHPLFHR 359 Query: 361 AMGNSAYQFRSADLADVRDIVNYIQQ 386 AMG AY RS D A+V I IQ+ Sbjct: 360 AMGAYAYLIRSPDRAEVIAIAQEIQR 385 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,396,888,836 Number of extensions: 101924274 Number of successful extensions: 248805 Number of sequences better than 1.0e-05: 120 Number of HSP's gapped: 248770 Number of HSP's successfully gapped: 120 Length of query: 389 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 251 Effective length of database: 1,760,596,133 Effective search space: 441909629383 Effective search space used: 441909629383 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 132 (55.5 bits)