BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0008.p (287 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8X4.1 B3K8X4_9BACI 4-diphosphocytidyl-2C-methyl-D-erythritol ... 468 e-130 B1DII4.1 B1DII4_9BACL 4-diphosphocytidyl-2C-methyl-D-erythritol ... 439 e-121 Q3EXJ6.1 Q3EXJ6_BACTI 4-diphosphocytidyl-2-C-methyl-D-erythritol... 356 1e-96 Q4MI15.1 Q4MI15_BACCE 4-diphosphocytidyl-2C-methyl-D-erythritol ... 354 6e-96 Q6HPX2.1 ISPE_BACHK 4-diphosphocytidyl-2-C-methyl-D-erythritol k... 354 6e-96 >B3K8X4.1 B3K8X4_9BACI 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Length = 284 Score = 468 bits (1203), Expect = e-130, Method: Compositional matrix adjust. Identities = 222/284 (78%), Positives = 245/284 (86%) Query: 4 LKMYEKAPAKINLMLDVLSKRADGFHEVEMIMTMVDLADRLELSELKRDSIIISSQAGYI 63 +K+YEKAPAKINLMLDVL KR DGFHEVEM+MTM+DLADRLE+SE KRD+III+SQAGYI Sbjct: 1 MKIYEKAPAKINLMLDVLHKRPDGFHEVEMVMTMIDLADRLEMSEQKRDTIIITSQAGYI 60 Query: 64 PLDEKNLAFQAARLIKDRYNVKSGVHIHLDKRIPVXXXXXXXXXXXXXTLRGLNRLWRLG 123 PLDEKNLAFQAARLIK+RY+V+ GVHIHLDK+IPV TLRGLNRLW LG Sbjct: 61 PLDEKNLAFQAARLIKERYDVRKGVHIHLDKKIPVAAGLAGGSSDAAATLRGLNRLWGLG 120 Query: 124 IPAQELQELGAELGSDVPFCVTGGTALATGRGERLTPIQSPPQCWVVLAKPPINVSTAEV 183 IP QEL LGAELGSDVPFCVTGGTALATGRGE LTPIQ+PPQCWV++AKPPINVSTAEV Sbjct: 121 IPQQELLALGAELGSDVPFCVTGGTALATGRGEVLTPIQNPPQCWVIVAKPPINVSTAEV 180 Query: 184 YGRVRANSIAVHPSASRMQAAIEAGDFAAVCAGLGNVLEDVTLKLHPEVQQLKEAMVKLG 243 YGR+R+ I HPSA RM A+ G F +C LGNVLE+VTLK+HPEVQQLKE M+KLG Sbjct: 181 YGRLRSEQIQSHPSAERMMDALAQGSFQQMCQSLGNVLEEVTLKMHPEVQQLKEGMLKLG 240 Query: 244 ADGVLMSGSGPTVFGLVSKQSKVARIYNGLRGFCKEVYAVRSLS 287 ADG LMSGSGPTVFGLVSK+SKVARIYNGLRGFCKEVYAVR L+ Sbjct: 241 ADGALMSGSGPTVFGLVSKESKVARIYNGLRGFCKEVYAVRLLT 284 >B1DII4.1 B1DII4_9BACL 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Length = 284 Score = 439 bits (1129), Expect = e-121, Method: Compositional matrix adjust. Identities = 212/284 (74%), Positives = 239/284 (84%) Query: 4 LKMYEKAPAKINLMLDVLSKRADGFHEVEMIMTMVDLADRLELSELKRDSIIISSQAGYI 63 +K+YEKAPAKINL+LDVL KR DGFHEVEMIMTMVDLADRLEL EL RD+IIISSQAGYI Sbjct: 1 MKIYEKAPAKINLLLDVLRKREDGFHEVEMIMTMVDLADRLELEELPRDTIIISSQAGYI 60 Query: 64 PLDEKNLAFQAARLIKDRYNVKSGVHIHLDKRIPVXXXXXXXXXXXXXTLRGLNRLWRLG 123 PLDEKNLAFQAARLIK+RY+V+ GV+IHLDK+IPV LRGLNRLW+L Sbjct: 61 PLDEKNLAFQAARLIKERYDVRKGVYIHLDKKIPVAAGLAGGSSDAAAALRGLNRLWQLN 120 Query: 124 IPAQELQELGAELGSDVPFCVTGGTALATGRGERLTPIQSPPQCWVVLAKPPINVSTAEV 183 I EL LGAELGSDVPFCVTGGTA+A GRGE+L I +PPQCWVVLAKPPINVSTA+V Sbjct: 121 ISEDELCRLGAELGSDVPFCVTGGTAIARGRGEKLERISNPPQCWVVLAKPPINVSTADV 180 Query: 184 YGRVRANSIAVHPSASRMQAAIEAGDFAAVCAGLGNVLEDVTLKLHPEVQQLKEAMVKLG 243 YG++RAN + HPS M +AIE G F+ +CAGLGNVLE+VTL L+PEV QLKE+M KLG Sbjct: 181 YGKLRANELKNHPSTKDMVSAIERGSFSDICAGLGNVLENVTLDLYPEVLQLKESMQKLG 240 Query: 244 ADGVLMSGSGPTVFGLVSKQSKVARIYNGLRGFCKEVYAVRSLS 287 ADGVLMSGSGPTVFGLVSK++K+ RIYNGLRGFCKEVY VR L+ Sbjct: 241 ADGVLMSGSGPTVFGLVSKEAKLPRIYNGLRGFCKEVYVVRMLT 284 >Q3EXJ6.1 Q3EXJ6_BACTI 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase EC=2.7.1.148 Length = 292 Score = 356 bits (913), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 168/286 (58%), Positives = 213/286 (74%), Gaps = 1/286 (0%) Query: 1 VNALKMYEKAPAKINLMLDVLSKRADGFHEVEMIMTMVDLADRLELSELKRDSIIISSQA 60 +N LK+ KAPAKINL LDVL KR DG+HEV+MIMT +DLADRLEL+EL D I I S Sbjct: 1 MNRLKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELTELAEDRIEILSHN 60 Query: 61 GYIPLDEKNLAFQAARLIKDRYNVKSGVHIHLDKRIPVXXXXXXXXXXXXXTLRGLNRLW 120 Y+P D++NLA+QAA+L+K+++NVK GV I ++K IPV TLRGLN+LW Sbjct: 61 RYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLW 120 Query: 121 RLGIPAQELQELGAELGSDVPFCVTGGTALATGRGERLTPIQSPPQCWVVLAKPPINVST 180 LG+ EL ELGAE+GSDV FCV GGTA+ATGRGE++ I++PP CWV+LAKP I VST Sbjct: 121 NLGLTIDELAELGAEIGSDVSFCVYGGTAIATGRGEKIEHIKTPPSCWVILAKPHIGVST 180 Query: 181 AEVYGRVRANSIAVHPSASRMQAAIEAGDFAAVCAGLGNVLEDVTLKLHPEVQQLKEAMV 240 A+VYG ++ N + HP+ +M I +GD+ +C +GNVLEDVT +HPEV ++K M Sbjct: 181 ADVYGNLKLNRVT-HPNVDKMVDVINSGDYKGICDTVGNVLEDVTFGMHPEVARIKSQMK 239 Query: 241 KLGADGVLMSGSGPTVFGLVSKQSKVARIYNGLRGFCKEVYAVRSL 286 + GAD VLMSGSGPTVFGLV S++ RIYNGL+GFC++VYAVR L Sbjct: 240 RFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLL 285 >Q4MI15.1 Q4MI15_BACCE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase EC=2.7.1.148 Length = 292 Score = 354 bits (908), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 168/286 (58%), Positives = 212/286 (74%), Gaps = 1/286 (0%) Query: 1 VNALKMYEKAPAKINLMLDVLSKRADGFHEVEMIMTMVDLADRLELSELKRDSIIISSQA 60 +N LK+ KAPAKINL LDVL KR DG+HEV+MIMT +DLADRLEL EL D I I S Sbjct: 1 MNRLKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELMELAEDRIEILSHN 60 Query: 61 GYIPLDEKNLAFQAARLIKDRYNVKSGVHIHLDKRIPVXXXXXXXXXXXXXTLRGLNRLW 120 Y+P D++NLA+QAA+L+K+++NVK GV I ++K IPV TLRGLN+LW Sbjct: 61 RYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLW 120 Query: 121 RLGIPAQELQELGAELGSDVPFCVTGGTALATGRGERLTPIQSPPQCWVVLAKPPINVST 180 LG+ +L ELGAE+GSDV FCV GGTA+ATGRGE++ I++PP CWV+LAKP I VST Sbjct: 121 NLGLTIDQLAELGAEIGSDVSFCVYGGTAIATGRGEQIEHIKTPPSCWVILAKPHIGVST 180 Query: 181 AEVYGRVRANSIAVHPSASRMQAAIEAGDFAAVCAGLGNVLEDVTLKLHPEVQQLKEAMV 240 A+VYG ++ N + HP+ +M I AGD+ +C +GNVLEDVT +HPEV ++K M Sbjct: 181 ADVYGNLKLNRVT-HPNVDKMVDVINAGDYKGICDTVGNVLEDVTFAMHPEVARIKAQMK 239 Query: 241 KLGADGVLMSGSGPTVFGLVSKQSKVARIYNGLRGFCKEVYAVRSL 286 + GAD VLMSGSGPTVFGLV S++ RIYNGL+GFC++VYAVR L Sbjct: 240 RFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLL 285 >Q6HPX2.1 ISPE_BACHK 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase EC=2.7.1.148 Length = 292 Score = 354 bits (908), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 168/286 (58%), Positives = 212/286 (74%), Gaps = 1/286 (0%) Query: 1 VNALKMYEKAPAKINLMLDVLSKRADGFHEVEMIMTMVDLADRLELSELKRDSIIISSQA 60 +N LK+ KAPAKINL LDVL KR DG+HEV+MIMT +DLADRLEL EL D I I S Sbjct: 1 MNRLKLLVKAPAKINLSLDVLGKRQDGYHEVKMIMTTIDLADRLELMELAEDRIEILSHN 60 Query: 61 GYIPLDEKNLAFQAARLIKDRYNVKSGVHIHLDKRIPVXXXXXXXXXXXXXTLRGLNRLW 120 Y+P D++NLA+QAA+L+K+++NVK GV I ++K IPV TLRGLN+LW Sbjct: 61 RYVPDDQRNLAYQAAKLLKEKFNVKKGVSITIEKTIPVAAGLAGGSSDAAATLRGLNKLW 120 Query: 121 RLGIPAQELQELGAELGSDVPFCVTGGTALATGRGERLTPIQSPPQCWVVLAKPPINVST 180 LG+ +L ELGAE+GSDV FCV GGTA+ATGRGE++ I++PP CWV+LAKP I VST Sbjct: 121 NLGLTIDQLAELGAEIGSDVSFCVYGGTAIATGRGEQIEHIKTPPSCWVILAKPHIGVST 180 Query: 181 AEVYGRVRANSIAVHPSASRMQAAIEAGDFAAVCAGLGNVLEDVTLKLHPEVQQLKEAMV 240 A+VYG ++ N + HP+ +M I AGD+ +C +GNVLEDVT +HPEV ++K M Sbjct: 181 ADVYGNLKLNRVT-HPNVDKMVDVINAGDYKGICDTVGNVLEDVTFAMHPEVARIKAQMK 239 Query: 241 KLGADGVLMSGSGPTVFGLVSKQSKVARIYNGLRGFCKEVYAVRSL 286 + GAD VLMSGSGPTVFGLV S++ RIYNGL+GFC++VYAVR L Sbjct: 240 RFGADAVLMSGSGPTVFGLVHHDSRMHRIYNGLKGFCEQVYAVRLL 285 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,494,393,718 Number of extensions: 56278735 Number of successful extensions: 203847 Number of sequences better than 1.0e-05: 1278 Number of HSP's gapped: 201839 Number of HSP's successfully gapped: 1279 Length of query: 287 Length of database: 3,060,696,203 Length adjustment: 134 Effective length of query: 153 Effective length of database: 1,798,280,193 Effective search space: 275136869529 Effective search space used: 275136869529 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)