BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0007.p (290 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8X5.1 B3K8X5_9BACI Pur operon repressor 465 e-129 C0ZHD0.1 C0ZHD0_BREBN Transcriptional repressor of purine operon 352 2e-95 A6CR39.1 A6CR39_9BACI Purine operon repressor 338 3e-91 C5D368.1 C5D368_9BACI Purine operon repressor, PurR 337 9e-91 Q2B0E3.1 Q2B0E3_9BACI Purine operon repressor 336 1e-90 >B3K8X5.1 B3K8X5_9BACI Pur operon repressor Length = 275 Score = 465 bits (1196), Expect = e-129, Method: Compositional matrix adjust. Identities = 227/273 (83%), Positives = 250/273 (91%) Query: 16 VKKLKRSQRLVDMTQFLLEKPHDLLPLSTFADRYGAAKSSISEDLAIIKEVFEGEGMGEL 75 +KKLKRS+RLVDMTQ+LL KPH L+PL+TFA+RYGAAKSSISEDLAIIK+VFE EG+GEL Sbjct: 1 MKKLKRSERLVDMTQYLLSKPHTLIPLTTFAERYGAAKSSISEDLAIIKDVFESEGLGEL 60 Query: 76 QTLAGAAGGVRYIPRMPTDMALAFVDGLCGQLEQSDRILPGGYLYMSDLLGLPSLMEQAG 135 QTLAGAAGGVRYIP++ D AL F + LC QL+QSDRILPGGYLYMSDLLG P+LM +AG Sbjct: 61 QTLAGAAGGVRYIPKLRRDHALRFAEELCQQLQQSDRILPGGYLYMSDLLGQPTLMNEAG 120 Query: 136 KIIATAFYGVEIDVVMTVETKGIPLAYATAAQLGLPVVLVRRDHQVTEGSAVSINYVSGS 195 KIIATAF EIDVVMTVETKGIPLAYATAAQL LPVVLVRRDHQVTEGSAVSINYVSGS Sbjct: 121 KIIATAFSDREIDVVMTVETKGIPLAYATAAQLNLPVVLVRRDHQVTEGSAVSINYVSGS 180 Query: 196 HKSIHTMSLSRRALREKSRVLIVDDFMKAGGTVRGMVDLLGEFNAEVAGVGVLVESGAVE 255 HKSIHTMSLSRRAL+E+SRVLIVDDFMKAGGT++GMVDLLGEFNAEVAGVGVLVESG+VE Sbjct: 181 HKSIHTMSLSRRALKERSRVLIVDDFMKAGGTIQGMVDLLGEFNAEVAGVGVLVESGSVE 240 Query: 256 NEERLLHDYVSLVKLSEVDSKGRRISAHPGNYF 288 EERLL DY+SL LS+VDSK +RI+ PGNYF Sbjct: 241 TEERLLEDYISLAVLSDVDSKTKRITVKPGNYF 273 >C0ZHD0.1 C0ZHD0_BREBN Transcriptional repressor of purine operon Length = 277 Score = 352 bits (903), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 179/273 (65%), Positives = 218/273 (79%), Gaps = 1/273 (0%) Query: 16 VKKLKRSQRLVDMTQFLLEKPHDLLPLSTFADRYGAAKSSISEDLAIIKEVFEGEGMGEL 75 +KKL+RS RLVDMTQ LL PH L PL+ FA++YGAAKSSISEDL+IIKE FE +G+G L Sbjct: 1 MKKLRRSARLVDMTQHLLAHPHTLTPLTLFAEQYGAAKSSISEDLSIIKEAFEVQGVGLL 60 Query: 76 QTLAGAAGGVRYIPRMPTDMALAFVDGLCGQLEQSDRILPGGYLYMSDLLGLPSLMEQAG 135 +T+AGAAGGV+YIP++ T+ AL F+ L GQL +R+LPGGYLYMSD+LG P M + G Sbjct: 61 KTVAGAAGGVKYIPQVKTEEALHFMRELIGQLANPERLLPGGYLYMSDILGNPQTMAKIG 120 Query: 136 KIIATAFYGVEIDVVMTVETKGIPLAYATAAQLGLPVVLVRRDHQVTEGSAVSINYVSGS 195 K+ ATA+ +DVVMTVETKGIPLAYATA L +PVV+VRRD++VTEGS VSINYVSGS Sbjct: 121 KLFATAYADKNVDVVMTVETKGIPLAYATAMFLNVPVVIVRRDNKVTEGSVVSINYVSGS 180 Query: 196 HKSIHTMSLSRRALREKSRVLIVDDFMKAGGTVRGMVDLLGEFNAEVAGVGVLVESGAVE 255 K I TMSL+RR L E+SRVLIVDDFMKAGGT+RGM+DLL EF A V G GVLVE+ A + Sbjct: 181 SKRIQTMSLARRGLAEQSRVLIVDDFMKAGGTLRGMIDLLQEFRATVVGCGVLVETTA-D 239 Query: 256 NEERLLHDYVSLVKLSEVDSKGRRISAHPGNYF 288 ERL+ +YVSL KL +VD KG++I G++F Sbjct: 240 VSERLVDEYVSLAKLQDVDFKGKQIEIELGSFF 272 >A6CR39.1 A6CR39_9BACI Purine operon repressor Length = 282 Score = 338 bits (867), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 164/271 (60%), Positives = 214/271 (78%), Gaps = 2/271 (0%) Query: 18 KLKRSQRLVDMTQFLLEKPHDLLPLSTFADRYGAAKSSISEDLAIIKEVFEGEGMGELQT 77 K KRS+RL+DMT +LLE+PH L+PL+ F++RY +AKSSISEDL IIKE FE G+G +QT Sbjct: 2 KFKRSERLIDMTHYLLERPHQLVPLTFFSERYSSAKSSISEDLGIIKETFETRGVGTVQT 61 Query: 78 LAGAAGGVRYIPRMPTDMALAFVDGLCGQLEQSDRILPGGYLYMSDLLGLPSLMEQAGKI 137 + GAAGGVRYIP++ A + LC L +R+LPGGYLYM+DLLG P M++ GK+ Sbjct: 62 VPGAAGGVRYIPKVKVTNAKEVIAELCEHLANPERLLPGGYLYMTDLLGNPRAMDKVGKL 121 Query: 138 IATAFYGVEIDVVMTVETKGIPLAYATAAQLGLPVVLVRRDHQVTEGSAVSINYVSGSHK 197 A+AF +IDV+MTV TKGIP+A+A A+ + +PVV+VRRD +VTEGS VSINYVSGS+K Sbjct: 122 FASAFAESDIDVIMTVATKGIPIAHAIASHMNVPVVIVRRDSKVTEGSTVSINYVSGSNK 181 Query: 198 SIHTMSLSRRALREKSRVLIVDDFMKAGGTVRGMVDLLGEFNAEVAGVGVLVESGAVENE 257 I TM LS+R+L+E S+VLIVDDFMKAGGTV GM +LL EF+AE++G+ VLVE A + + Sbjct: 182 RIQTMVLSKRSLKEGSKVLIVDDFMKAGGTVNGMKNLLDEFSAELSGIAVLVE--AEKAD 239 Query: 258 ERLLHDYVSLVKLSEVDSKGRRISAHPGNYF 288 ERL+ +Y+SLVKLS+VD K ++I+ GNYF Sbjct: 240 ERLVDEYLSLVKLSDVDVKEKQINVSEGNYF 270 >C5D368.1 C5D368_9BACI Purine operon repressor, PurR Length = 274 Score = 337 bits (863), Expect = 9e-91, Method: Compositional matrix adjust. Identities = 167/273 (61%), Positives = 213/273 (78%), Gaps = 2/273 (0%) Query: 18 KLKRSQRLVDMTQFLLEKPHDLLPLSTFADRYGAAKSSISEDLAIIKEVFEGEGMGELQT 77 KL+RS RLVDMT +LLE+PH L+PL+ FADRY +AKSSISEDLAIIK+ FE +G+G ++T Sbjct: 2 KLRRSGRLVDMTHYLLERPHQLIPLTFFADRYESAKSSISEDLAIIKQTFEQQGIGTIKT 61 Query: 78 LAGAAGGVRYIPRMPTDMALAFVDGLCGQLEQSDRILPGGYLYMSDLLGLPSLMEQAGKI 137 L GAAGGV+YIP+M A V LC QL + DR+LPGGYLYM+D+LG P ++ + G++ Sbjct: 62 LPGAAGGVQYIPKMSKQEAEEIVTYLCEQLSRPDRLLPGGYLYMTDILGDPRIVNKIGRL 121 Query: 138 IATAFYGVEIDVVMTVETKGIPLAYATAAQLGLPVVLVRRDHQVTEGSAVSINYVSGSHK 197 A+ F +DVVMT+ TKGIPLAYA A L +PVV+VR D++VTEGS VSINYVSGS K Sbjct: 122 YASIFADRPVDVVMTIATKGIPLAYAVAHFLYVPVVIVRHDNKVTEGSMVSINYVSGSSK 181 Query: 198 SIHTMSLSRRALREKSRVLIVDDFMKAGGTVRGMVDLLGEFNAEVAGVGVLVESGAVENE 257 I TM L++R+L E + VLI+DDFMKAGGTV GMV+LL EFNA+++G+GVLVES E + Sbjct: 182 RIQTMVLAKRSLAEGANVLIIDDFMKAGGTVNGMVNLLNEFNAKLSGIGVLVESE--ETK 239 Query: 258 ERLLHDYVSLVKLSEVDSKGRRISAHPGNYFVF 290 ERL+ +Y+SLVKLS VD K ++I+ GNY F Sbjct: 240 ERLVDEYISLVKLSSVDVKEKQITVKAGNYIHF 272 >Q2B0E3.1 Q2B0E3_9BACI Purine operon repressor Length = 276 Score = 336 bits (862), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 166/271 (61%), Positives = 212/271 (78%), Gaps = 2/271 (0%) Query: 18 KLKRSQRLVDMTQFLLEKPHDLLPLSTFADRYGAAKSSISEDLAIIKEVFEGEGMGELQT 77 K +RS+RL+DMT +LLE P L+ L+ FADRYG+AKSSISEDLAIIKE FE G+G LQT Sbjct: 3 KFRRSERLIDMTNYLLEHPRQLVSLTFFADRYGSAKSSISEDLAIIKETFEQRGIGTLQT 62 Query: 78 LAGAAGGVRYIPRMPTDMALAFVDGLCGQLEQSDRILPGGYLYMSDLLGLPSLMEQAGKI 137 + GAAGGV+Y ++ D A F+ GLC + +R+LPGGYLYM+D+LG P+++++AG++ Sbjct: 63 VPGAAGGVKYSVKVSDDEARPFISGLCEVIASPERLLPGGYLYMTDILGDPAIVQKAGRV 122 Query: 138 IATAFYGVEIDVVMTVETKGIPLAYATAAQLGLPVVLVRRDHQVTEGSAVSINYVSGSHK 197 A+AF +IDVVMTV TKGIPLAYA A L +PVV+VRRD +VTEGS VSINYVSGS K Sbjct: 123 FASAFADADIDVVMTVATKGIPLAYAVGAYLNVPVVIVRRDSRVTEGSTVSINYVSGSAK 182 Query: 198 SIHTMSLSRRALREKSRVLIVDDFMKAGGTVRGMVDLLGEFNAEVAGVGVLVESGAVENE 257 I TM LS+R+L E S+VLIVDDFMKAGGTV GM+ +L EF A VAG+ VLVE A + E Sbjct: 183 RIQTMVLSKRSLEEGSKVLIVDDFMKAGGTVNGMISMLEEFKAHVAGIAVLVE--AEKAE 240 Query: 258 ERLLHDYVSLVKLSEVDSKGRRISAHPGNYF 288 ERL+ +Y+SLV+L++VD K ++I+ GNYF Sbjct: 241 ERLVDEYLSLVQLADVDVKEKKINVTEGNYF 271 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.138 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,654,446,088 Number of extensions: 67173662 Number of successful extensions: 194370 Number of sequences better than 1.0e-05: 1118 Number of HSP's gapped: 194144 Number of HSP's successfully gapped: 1118 Length of query: 290 Length of database: 3,060,696,203 Length adjustment: 134 Effective length of query: 156 Effective length of database: 1,798,280,193 Effective search space: 280531710108 Effective search space used: 280531710108 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)