BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0035.0005.p (463 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8X7.1 B3K8X7_9BACI UDP-N-acetylglucosamine pyrophosphorylase 731 0.0 B1DII0.1 B1DII0_9BACL UDP-N-acetylglucosamine pyrophosphorylase 650 0.0 C0KTY6.1 C0KTY6_BACME UDP-N-acetylglucosamine pyrophosphorylase 577 e-162 C5D371.1 C5D371_9BACI UDP-N-acetylglucosamine pyrophosphorylase 572 e-161 Q5L3V0.1 GLMU_GEOKA Bifunctional protein glmU UDP-N-acetylglucos... 569 e-160 >B3K8X7.1 B3K8X7_9BACI UDP-N-acetylglucosamine pyrophosphorylase Length = 464 Score = 731 bits (1888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/445 (79%), Positives = 388/445 (87%) Query: 1 MAVVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVLDTVKATGCQRTVVVVGHGAEKVKAYV 60 A+VLAAGQGKRMKSKLYKVLHPVCGKPMVGHV+ TV+ C+R+VVVVGHGAE V+ Y+ Sbjct: 4 FAIVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVVQTVQQVNCERSVVVVGHGAEAVRTYL 63 Query: 61 GQDAEYVLQETQLGTGHAVKQAKDLLGGEAGTTIVICGDTPLVTAETLEGLMALHEGQSA 120 AEYVLQE QLGTGHAVKQAK+LLGGE G+TIVICGDTPLVT+ETLE L+ LHE +A Sbjct: 64 QDAAEYVLQEQQLGTGHAVKQAKELLGGEEGSTIVICGDTPLVTSETLENLLKLHESSNA 123 Query: 121 AATVLTAVMDQPAGYGRIIRGEDGGVQKIVEQKDCTPEEAAVNEINTGTYCFDNAKLFAA 180 AATVLTA MD P GYGR+IRGEDG +IVEQKDC+PEE AV EINTGTYCFDN KLFAA Sbjct: 124 AATVLTAHMDNPKGYGRVIRGEDGSALRIVEQKDCSPEEDAVTEINTGTYCFDNKKLFAA 183 Query: 181 LDKVTNSNNQQEYYLTDVIGILRAQGDIVLGYQAHDAAESIGVNDRLALSEAESLMRQRI 240 LD VTN N QQEYYLTD IGIL+ G+ VL YQ D AESIGVNDRLALSEAE MR+RI Sbjct: 184 LDNVTNQNAQQEYYLTDCIGILKQAGETVLAYQTDDYAESIGVNDRLALSEAEGFMRERI 243 Query: 241 NRQHMLNGVTIIDPASTYIAADVVIGADTTLYPGTVLKGKTVIGEDCIIGPSSEIENCVI 300 NR HMLNGVTIIDPASTYI ADV IG+DT LYPGTVLKG TVIGEDC+IGP ++IE+ VI Sbjct: 244 NRSHMLNGVTIIDPASTYIGADVQIGSDTVLYPGTVLKGNTVIGEDCVIGPDTDIEDSVI 303 Query: 301 MNGAEVKHSVLNQAQVGARTSVGPFAYLRPGAVLGEEVKIGDFVEIKNASIGDGSKVSHL 360 +GA VKHSVL+ A+VG+RTSVGPFAYLRPGA LG +VK+GDFVE+KNA+I DGSKVSHL Sbjct: 304 ADGASVKHSVLSSAEVGSRTSVGPFAYLRPGAKLGADVKVGDFVEVKNATIDDGSKVSHL 363 Query: 361 SYVGDATVGKNVNVGCGAITVNYDGYNKSRTEIGDDAFIGSNVNLVAPVTVGKGAFVVAG 420 SYVGDA VGKNVN+GCGAITVNYDGYNKS TEI DDAFIGSNVNL+APV VGKGAFVVAG Sbjct: 364 SYVGDAKVGKNVNIGCGAITVNYDGYNKSITEIEDDAFIGSNVNLIAPVKVGKGAFVVAG 423 Query: 421 STITRSVSENDLAIARVRQENKPGY 445 STIT SVS+NDLAIAR RQENKPGY Sbjct: 424 STITHSVSDNDLAIARQRQENKPGY 448 >B1DII0.1 B1DII0_9BACL UDP-N-acetylglucosamine pyrophosphorylase Length = 466 Score = 650 bits (1676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/445 (71%), Positives = 367/445 (82%) Query: 1 MAVVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVLDTVKATGCQRTVVVVGHGAEKVKAYV 60 M +VLAAGQGKRMKSKLYKVLH V GKPMVGHVLDTV +RTVV+VGHGAE VK ++ Sbjct: 4 MTIVLAAGQGKRMKSKLYKVLHQVSGKPMVGHVLDTVNEAKSERTVVIVGHGAEMVKGFL 63 Query: 61 GQDAEYVLQETQLGTGHAVKQAKDLLGGEAGTTIVICGDTPLVTAETLEGLMALHEGQSA 120 G AEYVLQE QLGTGHAV+QA+ LLG E GTTIVICGDTPLV AET++ ++ALH A Sbjct: 64 GDRAEYVLQEQQLGTGHAVRQAEALLGSEEGTTIVICGDTPLVRAETIQSMLALHTSSGA 123 Query: 121 AATVLTAVMDQPAGYGRIIRGEDGGVQKIVEQKDCTPEEAAVNEINTGTYCFDNAKLFAA 180 AATVLTA D PAGYGR+IRG DG V +IVEQKDC+ EEAAV EINTGTYCFDN KLFAA Sbjct: 124 AATVLTASFDNPAGYGRVIRGADGAVLRIVEQKDCSAEEAAVKEINTGTYCFDNKKLFAA 183 Query: 181 LDKVTNSNNQQEYYLTDVIGILRAQGDIVLGYQAHDAAESIGVNDRLALSEAESLMRQRI 240 L +V N N Q EYYLTDVIGI R GD V Y D AE+IGVNDR+AL++AE MR+RI Sbjct: 184 LAEVKNENAQGEYYLTDVIGIFRGAGDTVQAYCTPDLAEAIGVNDRVALADAERFMRERI 243 Query: 241 NRQHMLNGVTIIDPASTYIAADVVIGADTTLYPGTVLKGKTVIGEDCIIGPSSEIENCVI 300 NR+H++ GVTIIDPA+TYI ADV IGADT +YPGTVL+GKTVIGEDC+IGP ++I + I Sbjct: 244 NRKHLIEGVTIIDPANTYIEADVRIGADTIIYPGTVLRGKTVIGEDCVIGPQADITDSEI 303 Query: 301 MNGAEVKHSVLNQAQVGARTSVGPFAYLRPGAVLGEEVKIGDFVEIKNASIGDGSKVSHL 360 NGA VK+S + + VG ++VGP+A LRPG+ LGE K+GDFVE+KNA++GDGSKVSHL Sbjct: 304 QNGAAVKYSTIADSVVGKDSTVGPYANLRPGSKLGEGCKVGDFVELKNATLGDGSKVSHL 363 Query: 361 SYVGDATVGKNVNVGCGAITVNYDGYNKSRTEIGDDAFIGSNVNLVAPVTVGKGAFVVAG 420 SYVGDA VGK+VN+GCGAITVNYDG+NK+ TEIGD+AF+GSNVNL+APV +G+GA+VVAG Sbjct: 364 SYVGDAVVGKDVNIGCGAITVNYDGFNKAITEIGDNAFVGSNVNLIAPVKLGEGAYVVAG 423 Query: 421 STITRSVSENDLAIARVRQENKPGY 445 STIT V DLAIAR RQENK GY Sbjct: 424 STITHDVPSGDLAIARQRQENKAGY 448 >C0KTY6.1 C0KTY6_BACME UDP-N-acetylglucosamine pyrophosphorylase Length = 459 Score = 577 bits (1486), Expect = e-162, Method: Compositional matrix adjust. Identities = 272/444 (61%), Positives = 341/444 (76%) Query: 2 AVVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVLDTVKATGCQRTVVVVGHGAEKVKAYVG 61 AV+LAAGQG RMKS LYKVLHPVCGKPMV HV+D + + VVGHGAEKVK++VG Sbjct: 6 AVILAAGQGTRMKSSLYKVLHPVCGKPMVQHVIDQLSRLDLTNLITVVGHGAEKVKSHVG 65 Query: 62 QDAEYVLQETQLGTGHAVKQAKDLLGGEAGTTIVICGDTPLVTAETLEGLMALHEGQSAA 121 + + LQE QLGT HAV QA+ LL E GTTIV+CGDTPL+TAET+E L+ HE +A Sbjct: 66 DKSLFALQEEQLGTAHAVMQAESLLAHEKGTTIVVCGDTPLITAETIESLLKHHEATNAM 125 Query: 122 ATVLTAVMDQPAGYGRIIRGEDGGVQKIVEQKDCTPEEAAVNEINTGTYCFDNAKLFAAL 181 AT+LTA + P GYGRIIR E G V+KIVE KD T +E V EINTGTYCFDN KLF L Sbjct: 126 ATILTAHAEDPTGYGRIIRNEQGSVEKIVEHKDATEQERLVQEINTGTYCFDNEKLFETL 185 Query: 182 DKVTNSNNQQEYYLTDVIGILRAQGDIVLGYQAHDAAESIGVNDRLALSEAESLMRQRIN 241 KV+N N Q EYYL DVI IL+ +G I+ YQ D AE++GVNDR ALS+AE M++RIN Sbjct: 186 SKVSNDNVQGEYYLPDVIEILKNEGQIISAYQTSDFAETLGVNDRFALSQAEETMKKRIN 245 Query: 242 RQHMLNGVTIIDPASTYIAADVVIGADTTLYPGTVLKGKTVIGEDCIIGPSSEIENCVIM 301 +QHMLNGVTI+DP++TYI+AD VIG DT +YPGTV++G VIGE+C +GP+SEI++C I Sbjct: 246 KQHMLNGVTIVDPSNTYISADAVIGRDTFIYPGTVIQGTVVIGENCEVGPNSEIKDCKIG 305 Query: 302 NGAEVKHSVLNQAQVGARTSVGPFAYLRPGAVLGEEVKIGDFVEIKNASIGDGSKVSHLS 361 N ++HSV + +++G ++GPFA++RP +++G+EV++G+FVEIK AS G GSK SHLS Sbjct: 306 NNTSIRHSVAHDSEIGHEVTIGPFAHIRPQSLIGDEVRVGNFVEIKKASFGKGSKASHLS 365 Query: 362 YVGDATVGKNVNVGCGAITVNYDGYNKSRTEIGDDAFIGSNVNLVAPVTVGKGAFVVAGS 421 Y+GDA VGK VN+GCG+ITVNYDG NK T+I D AF+G N NL+APVT+G+GA+V AGS Sbjct: 366 YIGDAEVGKGVNLGCGSITVNYDGKNKFLTKIEDGAFVGCNSNLIAPVTIGEGAYVAAGS 425 Query: 422 TITRSVSENDLAIARVRQENKPGY 445 T+T V L+IAR +Q NK Y Sbjct: 426 TVTDDVPGKALSIARAKQVNKENY 449 >C5D371.1 C5D371_9BACI UDP-N-acetylglucosamine pyrophosphorylase Length = 459 Score = 572 bits (1475), Expect = e-161, Method: Compositional matrix adjust. Identities = 274/444 (61%), Positives = 343/444 (77%) Query: 2 AVVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVLDTVKATGCQRTVVVVGHGAEKVKAYVG 61 AV+LAAGQG RMKSK YKVLHPVCGKPMV HV+D V G ++ + VVG GAE+VKA +G Sbjct: 6 AVILAAGQGTRMKSKQYKVLHPVCGKPMVQHVVDQVLQLGIEKLITVVGFGAEQVKAQLG 65 Query: 62 QDAEYVLQETQLGTGHAVKQAKDLLGGEAGTTIVICGDTPLVTAETLEGLMALHEGQSAA 121 +EY Q+ QLGT HAV QA L + G T+V+CGDTPL+TAET++ L+ H +A Sbjct: 66 DQSEYAFQQEQLGTAHAVMQAAPYLQEKDGVTLVVCGDTPLITAETMQALLDHHLATNAK 125 Query: 122 ATVLTAVMDQPAGYGRIIRGEDGGVQKIVEQKDCTPEEAAVNEINTGTYCFDNAKLFAAL 181 AT+LTAV D PAGYGRI+R G V+KIVE KD + +E A+ EINTGTYCFDN LF AL Sbjct: 126 ATILTAVADNPAGYGRIVRDAHGNVEKIVEHKDASEQERAIKEINTGTYCFDNKSLFEAL 185 Query: 182 DKVTNSNNQQEYYLTDVIGILRAQGDIVLGYQAHDAAESIGVNDRLALSEAESLMRQRIN 241 V+N+N Q EYYLTDVI IL++ G I+ Y+A E+IGVNDR+AL+EAE +MR+RI Sbjct: 186 THVSNNNAQGEYYLTDVIEILKSNGSIISAYKAPSFEETIGVNDRVALAEAEKIMRERIC 245 Query: 242 RQHMLNGVTIIDPASTYIAADVVIGADTTLYPGTVLKGKTVIGEDCIIGPSSEIENCVIM 301 R+HM+NGVTIIDPA TYI+A+V IG DT +YPGTV++GKTVIGEDC IGP+SEI++C I Sbjct: 246 RKHMMNGVTIIDPAHTYISAEVRIGRDTVIYPGTVIEGKTVIGEDCTIGPNSEIKDCWIG 305 Query: 302 NGAEVKHSVLNQAQVGARTSVGPFAYLRPGAVLGEEVKIGDFVEIKNASIGDGSKVSHLS 361 NG ++HSV + +++G ++GPFA++RP + + +EV+IG+FVE+K ++ G GSK SHLS Sbjct: 306 NGTTIRHSVAHDSEIGNDVTIGPFAHIRPSSKIDDEVRIGNFVEVKKSTFGKGSKASHLS 365 Query: 362 YVGDATVGKNVNVGCGAITVNYDGYNKSRTEIGDDAFIGSNVNLVAPVTVGKGAFVVAGS 421 Y+GDA VG NVN+GCG+ITVNYDG NK T+I D AFIG N NL+APVTVGKGA+V AGS Sbjct: 366 YIGDAEVGVNVNLGCGSITVNYDGKNKHITKIEDGAFIGCNANLIAPVTVGKGAYVAAGS 425 Query: 422 TITRSVSENDLAIARVRQENKPGY 445 TIT V EN L+IAR RQ NK Y Sbjct: 426 TITDDVPENALSIARARQVNKENY 449 >Q5L3V0.1 GLMU_GEOKA Bifunctional protein glmU UDP-N-acetylglucosamine pyrophosphorylase Glucosamine-1-phosphate N-acetyltransferase EC=2.7.7.23 EC=2.3.1.157 Length = 458 Score = 569 bits (1467), Expect = e-160, Method: Compositional matrix adjust. Identities = 277/444 (62%), Positives = 340/444 (76%) Query: 2 AVVLAAGQGKRMKSKLYKVLHPVCGKPMVGHVLDTVKATGCQRTVVVVGHGAEKVKAYVG 61 AV+LAAGQG RMKSK YKVLHP+CGKPMV HV+D V G ++ + VVG GAE+VK +G Sbjct: 5 AVILAAGQGTRMKSKRYKVLHPICGKPMVQHVIDQVSKLGVEKAIAVVGFGAEQVKEQLG 64 Query: 62 QDAEYVLQETQLGTGHAVKQAKDLLGGEAGTTIVICGDTPLVTAETLEGLMALHEGQSAA 121 EY LQE QLGT HAV QA L G G TIV+CGDTPL+TAET+E L+ H A Sbjct: 65 SQCEYALQEEQLGTAHAVMQAAPHLRGLEGVTIVVCGDTPLITAETMEMLIEHHMAAKAK 124 Query: 122 ATVLTAVMDQPAGYGRIIRGEDGGVQKIVEQKDCTPEEAAVNEINTGTYCFDNAKLFAAL 181 ATVLTA+ D P+GYGRI+R E G V+KIVE KD + +E + EINTGTYCFDN LF AL Sbjct: 125 ATVLTAIADDPSGYGRIVRNEAGHVEKIVEHKDASEQERNIREINTGTYCFDNETLFQAL 184 Query: 182 DKVTNSNNQQEYYLTDVIGILRAQGDIVLGYQAHDAAESIGVNDRLALSEAESLMRQRIN 241 KVTN N Q EYYLTDVI I++A G +V YQA E+IGVNDR+AL+EAE +MR RI Sbjct: 185 TKVTNQNAQGEYYLTDVIEIIKADGGVVSAYQAPSFEETIGVNDRIALAEAERIMRARIC 244 Query: 242 RQHMLNGVTIIDPASTYIAADVVIGADTTLYPGTVLKGKTVIGEDCIIGPSSEIENCVIM 301 RQHM NGVTIIDPASTYI+A+ VIG DT +YPGTV++G+TVIGEDC+IGP+SEI+NC I Sbjct: 245 RQHMKNGVTIIDPASTYISAEAVIGRDTVIYPGTVIEGETVIGEDCVIGPNSEIKNCYIG 304 Query: 302 NGAEVKHSVLNQAQVGARTSVGPFAYLRPGAVLGEEVKIGDFVEIKNASIGDGSKVSHLS 361 + ++HSV + +++G+ ++GPFA++RP + + +EV+IG+FVE+K ++ G GSK SHLS Sbjct: 305 HRTSIRHSVAHDSEIGSDVTIGPFAHIRPLSKIDDEVRIGNFVEVKKSTFGKGSKASHLS 364 Query: 362 YVGDATVGKNVNVGCGAITVNYDGYNKSRTEIGDDAFIGSNVNLVAPVTVGKGAFVVAGS 421 Y+GDA VG +VN+GCG+ITVNYDG NK T+I D AFIG NVNL+APVTVG+GA+V AGS Sbjct: 365 YIGDAEVGADVNLGCGSITVNYDGVNKHMTKIEDGAFIGCNVNLIAPVTVGQGAYVAAGS 424 Query: 422 TITRSVSENDLAIARVRQENKPGY 445 TIT V LAIAR RQ NK Y Sbjct: 425 TITDDVPGRALAIARARQVNKEHY 448 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.133 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,610,712,782 Number of extensions: 111301071 Number of successful extensions: 272626 Number of sequences better than 1.0e-05: 2590 Number of HSP's gapped: 265777 Number of HSP's successfully gapped: 2634 Length of query: 463 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 324 Effective length of database: 1,751,175,118 Effective search space: 567380738232 Effective search space used: 567380738232 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 133 (55.8 bits)