BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0018.p (433 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4H9.1 B3K4H9_9BACI Aminotransferase class-III 569 e-160 B8CY58.1 B8CY58_HALOH 4-aminobutyrate aminotransferase EC=2.6.1.19 467 e-130 Q1PUR5.1 Q1PUR5_9BACT Strongly similar to aminotransferase class... 456 e-126 B7AYX5.1 B7AYX5_9FIRM Putative uncharacterized protein 444 e-123 C4V3S7.1 C4V3S7_9FIRM Alanine--glyoxylate transaminase EC=2.6.1.44 419 e-115 >B3K4H9.1 B3K4H9_9BACI Aminotransferase class-III Length = 432 Score = 569 bits (1466), Expect = e-160, Method: Compositional matrix adjust. Identities = 284/423 (67%), Positives = 329/423 (77%), Gaps = 3/423 (0%) Query: 8 IGRTAVAAKRKDYFYPCTAHFYRDAPQLVRGSMQFVYDEHGKQYTDFFAGVSVVACGHCN 67 IG AVAAKR+ Y YPCTAHFY + PQ+V G M +Y GK Y DFF GVSVVACGHCN Sbjct: 9 IGPEAVAAKRRRYGYPCTAHFYSEPPQIVGGKMHTLYGHDGKAYVDFFTGVSVVACGHCN 68 Query: 68 PVITARTIAQLQQLQHTSTVYLTQPNVDLAERLEE-VLPGKLRRSFFVNSGSEANEGALL 126 ITARTI QLQ LQHTST+YLTQP VDLAERL VLPG L+R+FFVNSGSEANEGALL Sbjct: 69 EAITARTIEQLQTLQHTSTIYLTQPMVDLAERLANGVLPGNLKRTFFVNSGSEANEGALL 128 Query: 127 LARMHTGRKGFIALESGLHGRTNLTMSVTGLQMWRTDQYLDEDVT-FIERPYDPKLTLDE 185 AR+HT R+ F+ALE GLHGRT LTM+VTG+ MWR D +LDEDV FI RPYDP + D Sbjct: 129 AARLHTKRRSFLALEYGLHGRTFLTMNVTGIPMWRADDFLDEDVAAFIPRPYDPGMDQDA 188 Query: 186 AAAVSLKSLERVLKEKGDTVAAMIVEPIQGNGGMIMPAPAYFREVKTLLEQYGVLLIDDE 245 AA SL +L VL KGD+ AAMIVEPIQGNGGMI P YFRE+K +LE++G+LLI DE Sbjct: 189 AARRSLDALASVLATKGDSFAAMIVEPIQGNGGMIAPPDWYFRELKAMLEEHGILLIADE 248 Query: 246 IQTGYGRTGAMFAMEHFGVVPDIISMAKALGNGVPVAAFATTDEIAASLNRPSASTFGGN 305 IQTG GRTG MFA+EH+G+VPDI++MAKALGNGVP+ AF TTDEIAASLNRPSASTFGGN Sbjct: 249 IQTGCGRTGRMFAIEHYGIVPDILTMAKALGNGVPIGAFCTTDEIAASLNRPSASTFGGN 308 Query: 306 PVSAATALAVLDYIRDERLPERAAELGSRLKKGLESLKERYPGMITDVRGTGLMLGAELA 365 PVS+ATALAVLDYI E L ER+ +G RL +GL L+ RY +I DVRG G M GAE+ Sbjct: 309 PVSSATALAVLDYIEQEGLVERSLRVGGRLIEGLRELQGRYE-LIADVRGKGFMAGAEIR 367 Query: 366 GPDAAGSAELTDNVLEAMKDRGYLIGKNGVGRNVLAFQPPLVITAEDVDGMLAVLNEVLL 425 G SA TD +LE MKD G++IGKNGVGRNVLAFQP ++I E+++ ML L++VL Sbjct: 368 GATDEESAAWTDIILERMKDEGFIIGKNGVGRNVLAFQPAMIIPEEEIEAMLRALDKVLA 427 Query: 426 QVS 428 +S Sbjct: 428 GLS 430 >B8CY58.1 B8CY58_HALOH 4-aminobutyrate aminotransferase EC=2.6.1.19 Length = 437 Score = 467 bits (1202), Expect = e-130, Method: Compositional matrix adjust. Identities = 237/433 (54%), Positives = 304/433 (70%), Gaps = 8/433 (1%) Query: 4 EETVIGRTAVAAKRKDYFYPCTAHFYRDAPQLVRGSMQFVYDEHGKQYTDFFAGVSVVAC 63 E+ IG A+ K+K+Y PC HFY++ QLVR ++ YD+ GK+Y D FAGVSV+ Sbjct: 3 EKNYIGPDAIIDKKKEYLIPCVYHFYKNPMQLVRAKGKYFYDQAGKEYLDLFAGVSVMNA 62 Query: 64 GHCNPVITARTIAQLQQLQHTSTVYLTQPNVDLAERLEEVLPGKLRRSFFVNSGSEANEG 123 GHC+P IT R Q++ LQHT T+YL QP VDLAE+L EV PG L++SFFVNSG+EANEG Sbjct: 63 GHCHPEITDRVCEQVKTLQHTCTIYLNQPIVDLAEKLAEVTPGNLKKSFFVNSGTEANEG 122 Query: 124 ALLLARMHTGRKGFIALESGLHGRTNLTMSVTGLQMWRTDQYLDEDVTFIERPYDPKLTL 183 ALLLA+++TG +IAL+ GLHGRT+LTMS+TGL WRTD ++F Y + Sbjct: 123 ALLLAKLYTGNSEYIALKQGLHGRTHLTMSITGLSFWRTDPNPAGGISFAPDAYCYRCPY 182 Query: 184 D-EAAAVSLKSLERVLKEKGDT-----VAAMIVEPIQGNGGMIMPAPAYFREVKTLLEQY 237 E LK R +++ +T VAA+I EPIQGNGG+I P P YF+ V+ +L++Y Sbjct: 183 GLEYPGCDLKC-ARAIRDVIETSTSKQVAALIAEPIQGNGGIITPPPEYFKVVRDILDEY 241 Query: 238 GVLLIDDEIQTGYGRTGAMFAMEHFGVVPDIISMAKALGNGVPVAAFATTDEIAASLNRP 297 G LLI DE+QTG+GRTG MFA+E++GV PDI++MAKALGNGVP+ AF T+E+A RP Sbjct: 242 GALLIIDEVQTGFGRTGKMFAIENWGVTPDIMTMAKALGNGVPIGAFTATEEVADVYTRP 301 Query: 298 SASTFGGNPVSAATALAVLDYIRDERLPERAAELGSRLKKGLESLKERYPGMITDVRGTG 357 AST GGNPVSA LA L I +E+L E AAE+G K GLE+L +R+ +I DVRG G Sbjct: 302 GASTLGGNPVSATAGLATLKVIEEEKLTENAAEVGLYFKNGLENLAKRH-RIIGDVRGLG 360 Query: 358 LMLGAELAGPDAAGSAELTDNVLEAMKDRGYLIGKNGVGRNVLAFQPPLVITAEDVDGML 417 LMLGAEL + + + TD VLE MKDRG LIGKNG RNVLAFQPPL+I +DV+ ++ Sbjct: 361 LMLGAELVKENKEPAPDETDLVLEKMKDRGILIGKNGPSRNVLAFQPPLIINKKDVEQVI 420 Query: 418 AVLNEVLLQVSTE 430 A L+EVL +V E Sbjct: 421 ATLDEVLNEVEKE 433 >Q1PUR5.1 Q1PUR5_9BACT Strongly similar to aminotransferase class III EC=2.6.1.- Length = 427 Score = 456 bits (1174), Expect = e-126, Method: Compositional matrix adjust. Identities = 224/425 (52%), Positives = 292/425 (68%), Gaps = 7/425 (1%) Query: 8 IGRTAVAAKRKDYFYPCTAHFYRDAPQLVRGSMQFVYDEHGKQYTDFFAGVSVVACGHCN 67 IG A+ K+++Y PC HFY+ Q+VRG MQ++YD GK+Y D + GVSV+ GHCN Sbjct: 4 IGPEAILQKKQEYLIPCVYHFYKKPMQIVRGEMQYLYDHKGKKYLDLYGGVSVMNAGHCN 63 Query: 68 PVITARTIAQLQQLQHTSTVYLTQPNVDLAERLEEVLPGKLRRSFFVNSGSEANEGALLL 127 P I + AQ+ LQHT+T+YLTQP DLAE+L E+ PG L+RSFF SGSEANEGA L+ Sbjct: 64 PEIVEKICAQVNTLQHTTTIYLTQPIADLAEKLSEITPGNLKRSFFCASGSEANEGAALI 123 Query: 128 ARMHTGRKGFIALESGLHGRTNLTMSVTGLQMWRTDQYLDEDVTFIERPYDPK----LTL 183 +++ T + F+A+E GLHGRT LTM++TG+ MWRTD Y +VT I Y + LT Sbjct: 124 SQLFTKKSKFVAIEQGLHGRTKLTMNLTGIPMWRTDPYPSGNVTHIPAAYCYRCAYGLTY 183 Query: 184 DEAAAVSLKSLERVLKEKGDTVAAMIVEPIQGNGGMIMPAPAYFREVKTLLEQYGVLLID 243 + LE V+++ GD AA+I+EPIQGNGG+I P P YF+ ++ +L +Y VLLI Sbjct: 184 PNCDLKCARRLEDVVRD-GD-FAALIIEPIQGNGGIITPPPEYFQLIREILNKYKVLLIT 241 Query: 244 DEIQTGYGRTGAMFAMEHFGVVPDIISMAKALGNGVPVAAFATTDEIAASLNRPSASTFG 303 DE+QTG+GRTG MFA+EH+ VVPDI+ MAKAL NG P+ AF T D +A++ RP AST G Sbjct: 242 DEVQTGFGRTGKMFAIEHWDVVPDIMCMAKALANGTPLGAFITNDAVASAYTRPGASTTG 301 Query: 304 GNPVSAATALAVLDYIRDERLPERAAELGSRLKKGLESLKERYPGMITDVRGTGLMLGAE 363 GNPVSA ALA +D I + RL E+A ELG K L L+++Y +I DVRG GLMLG E Sbjct: 302 GNPVSATAALATIDVIENYRLVEKAKELGDYFKNALNDLQQKY-RIIGDVRGMGLMLGVE 360 Query: 364 LAGPDAAGSAELTDNVLEAMKDRGYLIGKNGVGRNVLAFQPPLVITAEDVDGMLAVLNEV 423 L D + + TDN+LE +KD G L G+ G+ RNVL FQPPLVIT D+D + VL + Sbjct: 361 LVKEDKIPAFDETDNILEQLKDLGILAGRTGISRNVLTFQPPLVITQNDIDHLCMVLGII 420 Query: 424 LLQVS 428 L +VS Sbjct: 421 LSKVS 425 >B7AYX5.1 B7AYX5_9FIRM Putative uncharacterized protein Length = 435 Score = 444 bits (1143), Expect = e-123, Method: Compositional matrix adjust. Identities = 220/430 (51%), Positives = 289/430 (67%), Gaps = 10/430 (2%) Query: 4 EETVIGRTAVAAKRKDYFYPCTAHFYRDAPQLVRGSMQFVYDEHGKQYTDFFAGVSVVAC 63 + T IG A+ K+K Y PC HFY++ + VRGSMQ++YD G++Y D FAGVSV+ C Sbjct: 6 KRTYIGPEAIIEKKKKYIMPCLGHFYKEPREFVRGSMQYLYDSEGRKYLDCFAGVSVMNC 65 Query: 64 GHCNPVITARTIAQLQQLQHTSTVYLTQPNVDLAERLEEVLPGKLRRSFFVNSGSEANEG 123 GHCNP IT + Q+ LQH +YLT+ V+LAE+L V PGKL++SFF ++GSEA EG Sbjct: 66 GHCNPEITKKVQEQVGTLQHVCNIYLTENFVNLAEKLATVTPGKLQKSFFCSTGSEATEG 125 Query: 124 ALLLARMHTGRKGFIALESGLHGRTNLTMSVTGLQMWRTDQYLDEDVTFIERPYDPKL-- 181 ALLLA ++TG IAL +GLHGRT L MSVTG+QMWRTD + F PY + Sbjct: 126 ALLLASIYTGSSEIIALRNGLHGRTKLGMSVTGIQMWRTDPEPVGGIHFAPNPYCYRCPL 185 Query: 182 -----TLDEAAAVSLKSLERVLKEKGDTVAAMIVEPIQGNGGMIMPAPAYFREVKTLLEQ 236 T D A A ++ + + A I E IQGN G+++P YF+ VK +L Sbjct: 186 GKNRETCDLACANMVEDV--IQTSTAGHPGAFIAETIQGNAGIVVPPKGYFQRVKEILAA 243 Query: 237 YGVLLIDDEIQTGYGRTGAMFAMEHFGVVPDIISMAKALGNGVPVAAFATTDEIAASLNR 296 +G LL+ DE+QTG+ RTG +FA+EHFGV PDI++MAKALGNG P++AF +T EIA + R Sbjct: 244 HGTLLVIDEVQTGFARTGKLFAIEHFGVTPDIMAMAKALGNGAPISAFISTAEIADTYTR 303 Query: 297 PSASTFGGNPVSAATALAVLDYIRDERLPERAAELGSRLKKGLESLKERYPGMITDVRGT 356 P AST GGNPVS A LAVLDYI L + A E G +L+ GL +++++P +I D+RG Sbjct: 304 PGASTLGGNPVSTAAGLAVLDYIEKHDLCKNAEERGEQLRAGLREIQKKHP-IIGDIRGL 362 Query: 357 GLMLGAELAGPDAAGSAELTDNVLEAMKDRGYLIGKNGVGRNVLAFQPPLVITAEDVDGM 416 GLM GAE D + +A D+VLE +KDRG++IGKNG+ RNV+AFQPPLVITAED+D + Sbjct: 363 GLMTGAEFVHADKSPAAAELDDVLETLKDRGFIIGKNGIARNVMAFQPPLVITAEDIDNV 422 Query: 417 LAVLNEVLLQ 426 L L VL + Sbjct: 423 LNALEMVLTE 432 >C4V3S7.1 C4V3S7_9FIRM Alanine--glyoxylate transaminase EC=2.6.1.44 Length = 437 Score = 419 bits (1078), Expect = e-115, Method: Compositional matrix adjust. Identities = 200/429 (46%), Positives = 278/429 (64%), Gaps = 6/429 (1%) Query: 3 QEETVIGRTAVAAKRKDYFYPCTAHFYRDAPQLVRGSMQFVYDEHGKQYTDFFAGVSVVA 62 E + IG A+ K+K Y PC HFY D Q+VRGSMQ++YD G+ Y D FAGVSV+ Sbjct: 7 SEHSYIGAAAILEKKKKYIMPCLGHFYSDPRQIVRGSMQYLYDSEGRAYLDCFAGVSVIN 66 Query: 63 CGHCNPVITARTIAQLQQLQHTSTVYLTQPNVDLAERLEEVLPGKLRRSFFVNSGSEANE 122 CGHCNP I A Q+ LQH +YLT+ V+LAE+L + PG L++SFF ++G+EANE Sbjct: 67 CGHCNPEINAAVTEQVNTLQHVCNIYLTENFVNLAEQLARITPGALQKSFFCSTGTEANE 126 Query: 123 GALLLARMHTGRKGFIALESGLHGRTNLTMSVTGLQMWRTDQYLDEDVTFIERPYDPKLT 182 GA LLA + TG FIAL SGLHGRT LTMS+TG+ MWRTD ++F PY + Sbjct: 127 GAALLAEIATGSSEFIALRSGLHGRTKLTMSLTGIAMWRTDPNPVGGISFAPNPYCYRCP 186 Query: 183 LDEAAAVSLKSLERVLKEKGDTV-----AAMIVEPIQGNGGMIMPAPAYFREVKTLLEQY 237 + + + ++++ TV AA I E IQGN G+++P P YF+ +K +L + Sbjct: 187 MGKEYPACDLACANMVEDIIRTVTSGRPAAFIAETIQGNAGIVVPPPGYFKRIKEILTHF 246 Query: 238 GVLLIDDEIQTGYGRTGAMFAMEHFGVVPDIISMAKALGNGVPVAAFATTDEIAASLNRP 297 G L I DE+QTG+ RTG MF +EH+ V PDI++MAKALGNG P++AF T +A +P Sbjct: 247 GTLFIADEVQTGFARTGRMFGIEHYDVQPDIMTMAKALGNGAPISAFIATPTVADKYKKP 306 Query: 298 SASTFGGNPVSAATALAVLDYIRDERLPERAAELGSRLKKGLESLKERYPGMITDVRGTG 357 AST GGNPVS+ L V+ YI L A + G++L+ GL+ + R+P +I D+RG G Sbjct: 307 GASTLGGNPVSSTAGLGVIRYIESHDLMGNAEQRGAQLRAGLQEIAARHP-IIGDIRGLG 365 Query: 358 LMLGAELAGPDAAGSAELTDNVLEAMKDRGYLIGKNGVGRNVLAFQPPLVITAEDVDGML 417 LM+GAE D + + D VLE +K+RG+++GKNG+ RNV+AFQPPL+IT +++ +L Sbjct: 366 LMVGAEFVHADKSPAPAELDTVLEELKNRGFIVGKNGIARNVMAFQPPLIITEQNISDVL 425 Query: 418 AVLNEVLLQ 426 + +L + Sbjct: 426 NAVEIILTE 434 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,534,509,133 Number of extensions: 107823535 Number of successful extensions: 369550 Number of sequences better than 1.0e-05: 8537 Number of HSP's gapped: 338442 Number of HSP's successfully gapped: 8777 Length of query: 433 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 294 Effective length of database: 1,751,175,118 Effective search space: 514845484692 Effective search space used: 514845484692 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)