BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0027.p (448 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K8U1.1 B3K8U1_9BACI Chromosomal replication initiator protein ... 843 0.0 B1DC05.1 B1DC05_9BACL Chromosomal replication initiator protein ... 773 0.0 C0ZH37.1 C0ZH37_BREBN Chromosomal replication initiator protein ... 690 0.0 C1PE36.1 C1PE36_BACCO Chromosomal replication initiator protein ... 678 0.0 Q65PM2.1 DNAA_BACLD Chromosomal replication initiator protein dnaA 677 0.0 >B3K8U1.1 B3K8U1_9BACI Chromosomal replication initiator protein dnaA Length = 448 Score = 843 bits (2177), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/448 (90%), Positives = 427/448 (95%) Query: 1 VDSHTSELWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYT 60 ++SHTSELWQ+ILSIIQTKLSKPSFDTWFKATKALT + +++ISAPTTFAVEWLESRYT Sbjct: 1 MESHTSELWQEILSIIQTKLSKPSFDTWFKATKALTINDHSVVISAPTTFAVEWLESRYT 60 Query: 61 KLVGATVYEVTGEQVEVKFVIEENKPAEPVVQQTAPSPAVSREEAQTHLLNPKYTFDTFV 120 KLV ATV EV G+QV+V+FVIEE K EP QQ +P +S EE Q+H+LNPKYTFDTFV Sbjct: 61 KLVSATVLEVVGKQVDVRFVIEETKAHEPAPQQPSPPLEISGEEIQSHMLNPKYTFDTFV 120 Query: 121 IGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYVLEHNPNNKVIYIS 180 IGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHY+LEHNP++KV+YIS Sbjct: 121 IGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYILEHNPSSKVVYIS 180 Query: 181 SEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEERK 240 SEKFTNEFINSIRDNR ESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEERK Sbjct: 181 SEKFTNEFINSIRDNRAESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEERK 240 Query: 241 QIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPNEAM 300 QIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPNEAM Sbjct: 241 QIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPNEAM 300 Query: 301 MYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPKMITIGDIQQ 360 MYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRP+MITI DIQQ Sbjct: 301 MYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPRMITIQDIQQ 360 Query: 361 KVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVIHAH 420 KVGEYYNLR+EDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVIHAH Sbjct: 361 KVGEYYNLRLEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVIHAH 420 Query: 421 EKITQSLKVDQELYKVVNNLAEKIKNPS 448 EKITQSLK DQEL+KVVNN+ EKIKNP+ Sbjct: 421 EKITQSLKTDQELFKVVNNITEKIKNPT 448 >B1DC05.1 B1DC05_9BACL Chromosomal replication initiator protein dnaA Length = 450 Score = 773 bits (1996), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/449 (81%), Positives = 409/449 (91%), Gaps = 4/449 (0%) Query: 1 VDSHTSELWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYT 60 +DSHT +LWQQ+LSIIQTKLSKPSFDTWFKATKA + L ++APTTFA EWLE RYT Sbjct: 1 MDSHTYDLWQQVLSIIQTKLSKPSFDTWFKATKASFVNDSLLEVTAPTTFAAEWLEGRYT 60 Query: 61 KLVGATVYEVTGEQVEVKFVIEENKPAEP---VVQQTAPSPAVSREEAQTHLLNPKYTFD 117 KL+ T++E G QV+V+F IEE KPAEP ++ + A +P + +EE H+LNPKYTFD Sbjct: 61 KLIRNTLFEFLGRQVDVRFSIEEAKPAEPAPPILPKAAEAPII-QEETFNHMLNPKYTFD 119 Query: 118 TFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYVLEHNPNNKVI 177 TFVIG+ NRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHY+++HNP+ K++ Sbjct: 120 TFVIGANNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYIMDHNPSTKIM 179 Query: 178 YISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHE 237 YISSEKFTNEFIN+IRDNRGESFRNKYRN+D+LLIDDIQFLAGK+ TQEEFFHTFNALHE Sbjct: 180 YISSEKFTNEFINAIRDNRGESFRNKYRNIDVLLIDDIQFLAGKDGTQEEFFHTFNALHE 239 Query: 238 ERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPN 297 ERKQI+ISSDR PKEIPTLEERLRSRFEWGLITDIQ PDLETRIAILRKKAKAENLDIPN Sbjct: 240 ERKQIVISSDRTPKEIPTLEERLRSRFEWGLITDIQAPDLETRIAILRKKAKAENLDIPN 299 Query: 298 EAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPKMITIGD 357 EAM+YIANQIDTNIRELEGALIRVVAYSSL NQD+T+HLAAEALKDIIPSSRPKMITI D Sbjct: 300 EAMVYIANQIDTNIRELEGALIRVVAYSSLINQDITSHLAAEALKDIIPSSRPKMITIND 359 Query: 358 IQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVI 417 IQQKVGE+Y LR+E+FKARKRTKAVA+PRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVI Sbjct: 360 IQQKVGEFYGLRLEEFKARKRTKAVAYPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVI 419 Query: 418 HAHEKITQSLKVDQELYKVVNNLAEKIKN 446 HAHEKI+Q LK DQ+LYK++ NL EKIKN Sbjct: 420 HAHEKISQQLKQDQDLYKILQNLTEKIKN 448 >C0ZH37.1 C0ZH37_BREBN Chromosomal replication initiator protein DnaA Length = 453 Score = 690 bits (1781), Expect = 0.0, Method: Compositional matrix adjust. Identities = 332/450 (73%), Positives = 382/450 (84%), Gaps = 5/450 (1%) Query: 1 VDSHTSELWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYT 60 +D+ SELW+++L+ I+ LSKPSFDTW KATKA T ALI+ AP FA +WLE+RY Sbjct: 1 MDAAISELWRKVLAKIEKSLSKPSFDTWLKATKATTLEEDALIVVAPNDFARDWLETRYA 60 Query: 61 KLVGATVYEVTGEQVEVKFVIEENKPA-----EPVVQQTAPSPAVSREEAQTHLLNPKYT 115 +L+ T+YEVTG ++VKFV +N A +PV + P ++ +LNPKYT Sbjct: 61 QLITDTLYEVTGINMKVKFVALQNPDAAFADEQPVPRVKMSEPPTVADDQPPSILNPKYT 120 Query: 116 FDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYVLEHNPNNK 175 FDTFVIGSGNRFAHAASLAVAEAPAKAYNPLF+YGGVGLGKTHLMHAIGHYV++HNP+ K Sbjct: 121 FDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIQHNPSAK 180 Query: 176 VIYISSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNAL 235 V+Y+SSEKFTNEFINSIRDN+ FRNKYR+VD+LLIDDIQFLAGKESTQEEFFHTFNAL Sbjct: 181 VVYLSSEKFTNEFINSIRDNKAVEFRNKYRSVDVLLIDDIQFLAGKESTQEEFFHTFNAL 240 Query: 236 HEERKQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDI 295 HEE KQIIISSDRPPKEIPTLE+RLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDI Sbjct: 241 HEESKQIIISSDRPPKEIPTLEDRLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDI 300 Query: 296 PNEAMMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPKMITI 355 PNE M YIANQID+NIRELEGALIRVVAYSSL N+D+ T LAAEALKDIIPSSRP++ITI Sbjct: 301 PNEVMAYIANQIDSNIRELEGALIRVVAYSSLINRDIDTQLAAEALKDIIPSSRPRVITI 360 Query: 356 GDIQQKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTT 415 DIQ+ VGE ++L++EDFKA+KRTK VAFPRQIAMYLSRELTD SLPKIG+ FGGRDHTT Sbjct: 361 IDIQRTVGEAFSLKLEDFKAKKRTKTVAFPRQIAMYLSRELTDASLPKIGDEFGGRDHTT 420 Query: 416 VIHAHEKITQSLKVDQELYKVVNNLAEKIK 445 VIHAHEKI+++L D + + +L EK+K Sbjct: 421 VIHAHEKISRALANDPHMQTTIQSLIEKLK 450 >C1PE36.1 C1PE36_BACCO Chromosomal replication initiator protein DnaA Length = 449 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/447 (73%), Positives = 374/447 (83%), Gaps = 9/447 (2%) Query: 6 SELWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYTKLVGA 65 ++LW++ LS+I+ K+SKPSFDTW K+TKA + +IS P FA +WLE Y L+ Sbjct: 5 ADLWEKALSVIEKKISKPSFDTWLKSTKAYSLKNDTFVISVPNEFARDWLEGHYIPLITT 64 Query: 66 TVYEVTGEQVEVKFVIEENKPA-EPVVQQTAPSPAVSREEAQT-----HLLNPKYTFDTF 119 +Y++TGE++E+KFVI + + + EP + PSP S E+ +L PKYTFDTF Sbjct: 65 VLYDITGEELEIKFVIPQQQDSDEP---ELFPSPKKSAEKLNDTRDYQSMLIPKYTFDTF 121 Query: 120 VIGSGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYVLEHNPNNKVIYI 179 VIGSGNRFAHAASLAVAEAPAKAYNPLF+YGGVGLGKTHLMHAIGHYVLEHNP KV+Y+ Sbjct: 122 VIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVLEHNPKAKVVYL 181 Query: 180 SSEKFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEER 239 SSEKFTNEFINSIRDN+G FRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEE Sbjct: 182 SSEKFTNEFINSIRDNKGGEFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEES 241 Query: 240 KQIIISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPNEA 299 KQI+ISSDRPPKEIPTLEERLRSRFEWGLITDI PPDLETRIAILRKKAKA+ LDIPNE Sbjct: 242 KQIVISSDRPPKEIPTLEERLRSRFEWGLITDITPPDLETRIAILRKKAKADGLDIPNEV 301 Query: 300 MMYIANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPKMITIGDIQ 359 M+YIANQIDTNIRELEGALIRVVAYSSL N+D+ LAAEALKDIIPS++PK ITI DIQ Sbjct: 302 MLYIANQIDTNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPSAKPKTITIEDIQ 361 Query: 360 QKVGEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVIHA 419 + VGE Y+++MEDFKA+KRTK+VAFPRQIAMYLSRELTD+SLPKIGE FGGRDHTTVIHA Sbjct: 362 KVVGEEYHVKMEDFKAKKRTKSVAFPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHA 421 Query: 420 HEKITQSLKVDQELYKVVNNLAEKIKN 446 HEKI ++ D + K + L +KN Sbjct: 422 HEKIANLIQTDAQFQKKIEELQNLLKN 448 >Q65PM2.1 DNAA_BACLD Chromosomal replication initiator protein dnaA Length = 446 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/443 (72%), Positives = 380/443 (85%), Gaps = 4/443 (0%) Query: 6 SELWQQILSIIQTKLSKPSFDTWFKATKALTFSPQALIISAPTTFAVEWLESRYTKLVGA 65 S+LW Q L I+ KLSKPSF+TW K+TKA + LII+AP FA +WLESRY L+ Sbjct: 5 SDLWNQALGQIEKKLSKPSFETWMKSTKAHSLQGDTLIITAPNEFARDWLESRYLHLIAD 64 Query: 66 TVYEVTGEQVEVKFVIEENKPAEPVVQQTAPSPAVSREEAQT---HLLNPKYTFDTFVIG 122 T+Y++TGE++ +KFVI +N+ E + ++ P +S+EE ++LNPKYTFDTFVIG Sbjct: 65 TIYDLTGEELSIKFVIPQNQNEEDFMPKS-PIKKMSKEEPADFPQNMLNPKYTFDTFVIG 123 Query: 123 SGNRFAHAASLAVAEAPAKAYNPLFLYGGVGLGKTHLMHAIGHYVLEHNPNNKVIYISSE 182 SGNRFAHAASLAVAEAPAKAYNPLF+YGGVGLGKTHLMHAIGHYV++HNP+ KV+Y+SSE Sbjct: 124 SGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIDHNPSAKVVYLSSE 183 Query: 183 KFTNEFINSIRDNRGESFRNKYRNVDILLIDDIQFLAGKESTQEEFFHTFNALHEERKQI 242 KFTNEFINSIRDN+ FRN+YRNVD+LLIDDIQFLAGKE TQEEFFHTFN LHEE KQI Sbjct: 184 KFTNEFINSIRDNKAVDFRNRYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNTLHEETKQI 243 Query: 243 IISSDRPPKEIPTLEERLRSRFEWGLITDIQPPDLETRIAILRKKAKAENLDIPNEAMMY 302 +ISSDRPPKEIPTLE+RLRSRFEWGLITDI PPDLETRIAILRKKAKAE LDIPNE M+Y Sbjct: 244 VISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLY 303 Query: 303 IANQIDTNIRELEGALIRVVAYSSLTNQDVTTHLAAEALKDIIPSSRPKMITIGDIQQKV 362 IANQID+NIRELEGALIRVVAYSSL N+D+ LAAEALKDIIPSS+PK+ITI DIQ+ V Sbjct: 304 IANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPSSKPKVITIKDIQRIV 363 Query: 363 GEYYNLRMEDFKARKRTKAVAFPRQIAMYLSRELTDYSLPKIGEAFGGRDHTTVIHAHEK 422 G+ +N+++EDFKA+KRTK+VAFPRQIAMYLSRE+TD SLPKIGE FGGRDHTTVIHAHEK Sbjct: 364 GQQFNIKLEDFKAKKRTKSVAFPRQIAMYLSREMTDSSLPKIGEEFGGRDHTTVIHAHEK 423 Query: 423 ITQSLKVDQELYKVVNNLAEKIK 445 I++ L D++L + + + E+++ Sbjct: 424 ISKLLSDDEQLQQQIKEIKEQLR 446 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.132 0.375 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,620,927,851 Number of extensions: 109746661 Number of successful extensions: 348385 Number of sequences better than 1.0e-05: 2019 Number of HSP's gapped: 344986 Number of HSP's successfully gapped: 2023 Length of query: 448 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 309 Effective length of database: 1,751,175,118 Effective search space: 541113111462 Effective search space used: 541113111462 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)