BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0023.0012.p (582 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D7K4.1 B1D7K4_9BACL ABC transporter related 719 0.0 C1T827.1 C1T827_9FIRM ABC-type multidrug transport system, ATPas... 696 0.0 C4L3R0.1 C4L3R0_EXISA ABC transporter related 684 0.0 A6TQ67.1 A6TQ67_ALKMQ ABC transporter, transmembrane region 681 0.0 A6LV80.1 A6LV80_CLOB8 ABC transporter related 677 0.0 >B1D7K4.1 B1D7K4_9BACL ABC transporter related Length = 575 Score = 719 bits (1856), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/581 (63%), Positives = 445/581 (76%), Gaps = 11/581 (1%) Query: 2 KQLKPFKXXXXXXXXXXFLQSMGDLYLPTLMSDIVDKGIVQGDRSYIWKIGGFMLLVAAG 61 + LKPF+ FLQ++ DLYLPTLM+DIVDKG+ GD+SYIWKIGGFMLLVAA Sbjct: 6 RYLKPFRLFVIGVLVFVFLQTLSDLYLPTLMADIVDKGVSVGDKSYIWKIGGFMLLVAAA 65 Query: 62 GALCSIIASYLSAKVAAGFGKNTRSRMFNHVENFTLHEFDKLGTASLITRTTNDITQVQT 121 G +CS++ASY S+K A GFG++ RSR+F HVENF+L EFDK+GTASLITRTTNDITQVQ Sbjct: 66 GGICSVLASYFSSKSAMGFGRDVRSRVFKHVENFSLQEFDKIGTASLITRTTNDITQVQQ 125 Query: 122 VLTXXXXXXXXXXXXXXXXXXXXXSEDAKLSLIFVVVIPLLVGAILFIGMKGLPLFKAIQ 181 VL S+DAKLSL+FVVVIP+L GAI + KG+PLFKA+Q Sbjct: 126 VLIMILRMMITAPMMCIGGIIMAISKDAKLSLVFVVVIPVLAGAIFLVVRKGIPLFKAMQ 185 Query: 182 VKLDKLNRVLREHLTGIRVIRSFNRISHENERFTEANKDLTDTAIKVNKIMAGLMPLMMI 241 VK+DKLN VLRE LTGIRVIRSF+RI+HEN++F AN DLTDTA++VNKIMA LMPLMM+ Sbjct: 186 VKIDKLNLVLREGLTGIRVIRSFDRINHENKKFDAANADLTDTAVRVNKIMAVLMPLMML 245 Query: 242 VMNFSMIAILYYGGIRIGDGDLQVGSLMAFIQYAMQIMFSLIMVSMMFVLIPRASASALR 301 +MN S I I+ GGIRI G++Q+GSLMAFIQY MQIMFSL+M+SMM ++IPRA ASA+R Sbjct: 246 IMNISTIVIIAIGGIRIDHGNMQIGSLMAFIQYGMQIMFSLLMMSMMLIMIPRAQASAVR 305 Query: 302 INEVLDMQPEITDPXXXXXXXXXXXXRKDGRGNMHGFVEFDNVSFSYPGAEQPALAGISF 361 INEVL M P ++D + G+ G++EF V+FSYPGAEQPAL+ ISF Sbjct: 306 INEVLQMAPTLSDKDVTK--------KNSGK---EGYLEFRGVTFSYPGAEQPALSDISF 354 Query: 362 SAKPXXXXXXXXXXXXXXXXXXXMIPRFYDVSEGAVRVDGVDVREMTQEELRSKIGYIPQ 421 A P +IPRFYDV G + +DG+D+R+M+QE+LR KIG++PQ Sbjct: 355 QAGPGEITALIGGTGAGKSTLVSLIPRFYDVDAGQIIIDGMDIRDMSQEDLRHKIGFVPQ 414 Query: 422 KAVLFTGTINENIRYGKEEATEEEVIHAAKIAQAYDFVTAMKDGFNSEISQGGGNVSGGQ 481 KAVLFTGT+ ENIRYG+E AT+EEV HAA IAQA +F+ M G++S I+QGG NVSGGQ Sbjct: 415 KAVLFTGTVAENIRYGQENATDEEVAHAAAIAQASEFIGGMDQGYDSMIAQGGNNVSGGQ 474 Query: 482 KQRLSIARALVRKPEVYLFDDSFSALDFKTDAKLRAALKGETTESTVIIVAQRVSTVMDA 541 KQRLSIARALVR+PE+Y+FDDSFSALDFKTDAKLRAALK E STV++VAQRVSTVMDA Sbjct: 475 KQRLSIARALVRRPEIYVFDDSFSALDFKTDAKLRAALKSEVGNSTVMLVAQRVSTVMDA 534 Query: 542 DRIIVLDEGQIAGMGTHRELMDNSEVYREIVSSQLSEEEIA 582 DRIIVLDEG+IAG+G H+ELM EVY+EIVSSQLSEEEIA Sbjct: 535 DRIIVLDEGRIAGIGNHKELMQTCEVYKEIVSSQLSEEEIA 575 >C1T827.1 C1T827_9FIRM ABC-type multidrug transport system, ATPase and permease component Length = 575 Score = 696 bits (1797), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/579 (61%), Positives = 434/579 (74%), Gaps = 11/579 (1%) Query: 4 LKPFKXXXXXXXXXXFLQSMGDLYLPTLMSDIVDKGIVQGDRSYIWKIGGFMLLVAAGGA 63 LKPF QS+ DLYLPTLMS IVD GIV+GD YI +GG ML AA A Sbjct: 8 LKPFTWSVAAVLLLLLFQSLTDLYLPTLMSGIVDTGIVKGDTHYIVNVGGKMLFFAAVSA 67 Query: 64 LCSIIASYLSAKVAAGFGKNTRSRMFNHVENFTLHEFDKLGTASLITRTTNDITQVQTVL 123 LC I ASYLSAK+A G G+N R +F+ VE+++L+EFD++GTASLITRTTNDI Q+Q +L Sbjct: 68 LCMITASYLSAKIATGLGRNLRGMVFSRVESYSLNEFDRMGTASLITRTTNDINQIQQLL 127 Query: 124 TXXXXXXXXXXXXXXXXXXXXXSEDAKLSLIFVVVIPLLVGAILFIGMKGLPLFKAIQVK 183 S+DA LSL+FVVV+P++ G IL I K +PLFKA+QV Sbjct: 128 IIMMRMMISAPMMCIGGIIMAVSKDAVLSLVFVVVLPVIAGTILIIFRKAVPLFKAMQVN 187 Query: 184 LDKLNRVLREHLTGIRVIRSFNRISHENERFTEANKDLTDTAIKVNKIMAGLMPLMMIVM 243 LD+LNRVLRE LTGIRVIR+FNR+ HEN RF +AN DLTDTAI+VN IMAGLMP+MM+VM Sbjct: 188 LDQLNRVLREGLTGIRVIRAFNRLEHENARFLKANSDLTDTAIRVNIIMAGLMPVMMLVM 247 Query: 244 NFSMIAILYYGGIRIGDGDLQVGSLMAFIQYAMQIMFSLIMVSMMFVLIPRASASALRIN 303 N S IAI+++GGIR+ GD+QVG +MAF+QYAMQIMFSLIM+S MF++IPRA ASA+RIN Sbjct: 248 NLSSIAIVWFGGIRVDKGDMQVGDMMAFLQYAMQIMFSLIMISFMFIMIPRAEASAVRIN 307 Query: 304 EVLDMQPEITDPXXXXXXXXXXXXRKDGRGNMHGFVEFDNVSFSYPGAEQPALAGISFSA 363 EVLD+ PEI D R G+ GFVEF +V+FSYPGAE+PA++ ISF+A Sbjct: 308 EVLDLIPEIKDAE-----------RVKKAGDKKGFVEFKDVTFSYPGAEEPAISDISFTA 356 Query: 364 KPXXXXXXXXXXXXXXXXXXXMIPRFYDVSEGAVRVDGVDVREMTQEELRSKIGYIPQKA 423 P +IPRFYD+ +G++ +DGVDVREM+QE LRSKIG +PQKA Sbjct: 357 GPGEVTAIIGGTGSGKSTLINLIPRFYDIDKGSILIDGVDVREMSQESLRSKIGLVPQKA 416 Query: 424 VLFTGTINENIRYGKEEATEEEVIHAAKIAQAYDFVTAMKDGFNSEISQGGGNVSGGQKQ 483 V FTG+I NIRYG+E AT+EEV AA+IAQA +F+T MKDGF+S I+QGG NVSGGQKQ Sbjct: 417 VFFTGSIAANIRYGREAATDEEVRRAAEIAQATEFITGMKDGFDSVIAQGGTNVSGGQKQ 476 Query: 484 RLSIARALVRKPEVYLFDDSFSALDFKTDAKLRAALKGETTESTVIIVAQRVSTVMDADR 543 RLSIARALVR+PE+Y+ DD+ SALDFKTDA LRAAL+ ET +TV+IVAQRVSTVMDADR Sbjct: 477 RLSIARALVRRPEIYVIDDALSALDFKTDASLRAALRKETACATVLIVAQRVSTVMDADR 536 Query: 544 IIVLDEGQIAGMGTHRELMDNSEVYREIVSSQLSEEEIA 582 IIV+D+G+IAG+G HREL++ +VYREIV SQLSEEEIA Sbjct: 537 IIVMDKGKIAGIGRHRELLNTCDVYREIVVSQLSEEEIA 575 >C4L3R0.1 C4L3R0_EXISA ABC transporter related Length = 574 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/585 (57%), Positives = 424/585 (72%), Gaps = 18/585 (3%) Query: 1 MKQLKPFKXXXXXXXXXXFLQSMGDLYLPTLMSDIVDKGIVQGDRSYIWKIGGFMLLVAA 60 +K+L +K F QS+ DL+LPTLM+DI+D G+V GD YIW++GG ML V Sbjct: 5 LKRLVTYKWAVLIVLLFVFAQSLADLFLPTLMADIIDNGVVTGDTGYIWRMGGIMLCVTG 64 Query: 61 GGALCSIIASYLSAKVAAGFGKNTRSRMFNHVENFTLHEFDKLGTASLITRTTNDITQVQ 120 GAL +++AS+ S+K A GFG++ R R+FNHVE F+L EFD++GTASLITRTTNDITQVQ Sbjct: 65 LGALAAVVASFYSSKAAMGFGRDLRRRVFNHVERFSLEEFDRVGTASLITRTTNDITQVQ 124 Query: 121 TVLTXXXXXXXXXXXXXXXXXXXXXSEDAKLSLIFVVVIPLLVGAILFIGMKGLPLFKAI 180 V+ S+DAKLSL+ V +P+LV +I I K +PLFK + Sbjct: 125 QVIIMMLRMVVSAPIMFVGGLIMATSKDAKLSLVIVAAMPVLVLSIFLIFWKAMPLFKKV 184 Query: 181 QVKLDKLNRVLREHLTGIRVIRSFNRISHENERFTEANKDLTDTAIKVNKIMAGLMPLMM 240 Q +LD+LN VLRE+LTGIRVIR+FNR E R TEAN+ LTD +IKVN+IMA LMP+MM Sbjct: 185 QKRLDRLNLVLRENLTGIRVIRAFNREKEEQVRLTEANERLTDVSIKVNQIMAFLMPVMM 244 Query: 241 IVMNFSMIAILYYGGIRIGDGDLQVGSLMAFIQYAMQIMFSLIMVSMMFVLIPRASASAL 300 +VMN +++ ++++GGIRI +G +Q+G LMAFIQY MQIMF+L+M S+MF+++PRAS SA Sbjct: 245 LVMNLTVVGVIWFGGIRIDNGAMQIGDLMAFIQYVMQIMFALVMASVMFIMVPRASVSAN 304 Query: 301 RINEVLDMQPEITDPXXXXXXXXXXXXRKDGRGNM---HGFVEFDNVSFSYPGAEQPALA 357 RINEVL+M P + D DG G +EFD+V+F YPGAE+PAL+ Sbjct: 305 RINEVLEMTPSLID---------------DGTKTADVEKGTLEFDHVTFFYPGAEEPALS 349 Query: 358 GISFSAKPXXXXXXXXXXXXXXXXXXXMIPRFYDVSEGAVRVDGVDVREMTQEELRSKIG 417 +SFSAKP +IPRFYDV+ G +RV+GVDV+ + QEELRSKIG Sbjct: 350 NVSFSAKPGEVTAVIGGTGSGKSTLVNLIPRFYDVTSGTIRVNGVDVQAVPQEELRSKIG 409 Query: 418 YIPQKAVLFTGTINENIRYGKEEATEEEVIHAAKIAQAYDFVTAMKDGFNSEISQGGGNV 477 ++PQKA+LFTGTI ENIRYGK +AT EEV HAA IAQA DF+ M D + + I QGG NV Sbjct: 410 FVPQKALLFTGTIAENIRYGKADATAEEVAHAASIAQANDFIEKMPDRYEAVIEQGGSNV 469 Query: 478 SGGQKQRLSIARALVRKPEVYLFDDSFSALDFKTDAKLRAALKGETTESTVIIVAQRVST 537 SGGQKQRLSIARALVRKP++Y+FDDSFSALDFKTDA LR ALK ET ++TV+IVAQRVST Sbjct: 470 SGGQKQRLSIARALVRKPDLYVFDDSFSALDFKTDAALRKALKEETKDATVLIVAQRVST 529 Query: 538 VMDADRIIVLDEGQIAGMGTHRELMDNSEVYREIVSSQLSEEEIA 582 +MDADRIIVL+EG +AG+GTH EL + VY+EIV SQLSEEEIA Sbjct: 530 IMDADRIIVLEEGAVAGIGTHEELFATNAVYQEIVKSQLSEEEIA 574 >A6TQ67.1 A6TQ67_ALKMQ ABC transporter, transmembrane region Length = 576 Score = 681 bits (1758), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/582 (56%), Positives = 426/582 (73%), Gaps = 11/582 (1%) Query: 1 MKQLKPFKXXXXXXXXXXFLQSMGDLYLPTLMSDIVDKGIVQGDRSYIWKIGGFMLLVAA 60 ++ LKP++ FLQ + +L+LPTLM+DIVD G+V G+ SYI+K+G M+++A Sbjct: 5 LRYLKPYRLSVLSALGLVFLQVIAELFLPTLMADIVDIGVVTGNTSYIFKVGAIMMIIAL 64 Query: 61 GGALCSIIASYLSAKVAAGFGKNTRSRMFNHVENFTLHEFDKLGTASLITRTTNDITQVQ 120 G LC++ ASYLS+K A FG++ RS+MF E+F+L+EF+K+GT+SLITRTTNDITQ+Q Sbjct: 65 VGTLCAVYASYLSSKTAMAFGRDLRSQMFERAEDFSLNEFNKIGTSSLITRTTNDITQMQ 124 Query: 121 TVLTXXXXXXXXXXXXXXXXXXXXXSEDAKLSLIFVVVIPLLVGAILFIGMKGLPLFKAI 180 V+ S++A LSLI V V+P++ I+ + K PLFK + Sbjct: 125 QVVMMSLGMMARAPMMGIGGIIMAVSKNATLSLIIVFVVPVITLGIVVVAKKVTPLFKLM 184 Query: 181 QVKLDKLNRVLREHLTGIRVIRSFNRISHENERFTEANKDLTDTAIKVNKIMAGLMPLMM 240 Q KLD LN+VLRE LTG+RVIR+FNR+ HE +RF EAN DLT T+IKV KIMA +MP M Sbjct: 185 QTKLDNLNQVLRETLTGVRVIRAFNRVEHEKDRFKEANHDLTSTSIKVTKIMAVMMPAMS 244 Query: 241 IVMNFSMIAILYYGGIRIGDGDLQVGSLMAFIQYAMQIMFSLIMVSMMFVLIPRASASAL 300 ++ NF+ IA++++G RI +G +QVG LMAFIQY MQIMF+LIM+SMMFV+ PRASASA+ Sbjct: 245 LIFNFTTIAVIWFGATRIDNGTMQVGDLMAFIQYVMQIMFALIMLSMMFVMFPRASASAV 304 Query: 301 RINEVLDMQPEITDPXXXXXXXXXXXXRKDGRGNMHGFVEFDNVSFSYPGAEQPALAGIS 360 RINEV D PEI DP + G +EF +V+FSYPGAE P L IS Sbjct: 305 RINEVFDTIPEIKDPL-----------KSRATHTRDGLIEFKHVTFSYPGAEHPVLKDIS 353 Query: 361 FSAKPXXXXXXXXXXXXXXXXXXXMIPRFYDVSEGAVRVDGVDVREMTQEELRSKIGYIP 420 F+A+P +IPRFYD+ G + V+G+D+REMTQ+ LR KIG++P Sbjct: 354 FTARPNKITAIIGGTGSGKSTLVNLIPRFYDIDSGHILVNGMDIREMTQKSLRGKIGFVP 413 Query: 421 QKAVLFTGTINENIRYGKEEATEEEVIHAAKIAQAYDFVTAMKDGFNSEISQGGGNVSGG 480 Q+AVLFTGTI +NI+YGKE AT EE+ +A++IAQA DF++ MKDGF+S I+QGG N+SGG Sbjct: 414 QRAVLFTGTIADNIKYGKENATMEEIQYASEIAQATDFISNMKDGFDSVIAQGGTNLSGG 473 Query: 481 QKQRLSIARALVRKPEVYLFDDSFSALDFKTDAKLRAALKGETTESTVIIVAQRVSTVMD 540 QKQRLSIARALVR+PE+YLFDDSFSALDFKTD+KLR ALK ET +T IIVAQRV+T++D Sbjct: 474 QKQRLSIARALVRRPEIYLFDDSFSALDFKTDSKLRGALKNETKNATQIIVAQRVTTIID 533 Query: 541 ADRIIVLDEGQIAGMGTHRELMDNSEVYREIVSSQLSEEEIA 582 AD+IIVLD+GQIAG+GTH+EL+ +VYREIVSSQLSEEE+A Sbjct: 534 ADQIIVLDKGQIAGIGTHKELLKTCDVYREIVSSQLSEEEMA 575 >A6LV80.1 A6LV80_CLOB8 ABC transporter related Length = 591 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/596 (57%), Positives = 433/596 (72%), Gaps = 29/596 (4%) Query: 4 LKPFKXXXXXXXXXXFLQSMGDLYLPTLMSDIVDKGIVQGDR----------------SY 47 LK + F Q + +LYLPTLM+DIVDKGIVQ D Y Sbjct: 8 LKQYTVNIIIIVLLVFTQVIANLYLPTLMADIVDKGIVQKDVVQTISFLGYNGEYSGVDY 67 Query: 48 IWKIGGFMLLVAAGGALCSIIASYLSAKVAAGFGKNTRSRMFNHVENFTLHEFDKLGTAS 107 I +IGG MLLV+ GGA+CSII+S+LS++ A GF K R+++F VE+F+L+EFDK GTA+ Sbjct: 68 ILRIGGLMLLVSLGGAICSIISSFLSSRTAIGFAKIIRNKLFTKVESFSLNEFDKFGTAT 127 Query: 108 LITRTTNDITQVQTVLTXXXXXXXXXXXXXXXXXXXXXSEDAKLSLIFVVVIPLLVGAIL 167 LITRTTND+TQVQ+V E+ L+ IF VVIPLL I+ Sbjct: 128 LITRTTNDVTQVQSVTIMMFSIALFAPLTALGGVVMALRENVTLTWIFAVVIPLL-AVII 186 Query: 168 FIGMK-GLPLFKAIQVKLDKLNRVLREHLTGIRVIRSFNRISHENERFTEANKDLTDTAI 226 + +K +PLFK +QVK+DKLN VLRE LTGIRV+R+FNRI+ E RF +ANKDL + AI Sbjct: 187 GLTLKFAMPLFKLMQVKIDKLNLVLREGLTGIRVVRAFNRINTEKVRFDDANKDLMNNAI 246 Query: 227 KVNKIMAGLMPLMMIVMNFSMIAILYYGGIRIGDGDLQVGSLMAFIQYAMQIMFSLIMVS 286 KVNKIMA LMP+MM +MN + +A++++G IRI G+++VGSL+AF+QY MQI+F +M+ Sbjct: 247 KVNKIMAILMPIMMFIMNATTVAVIWFGSIRIDSGNMEVGSLIAFMQYGMQILFGFLMLG 306 Query: 287 MMFVLIPRASASALRINEVLDMQPEITDPXXXXXXXXXXXXRKDGRGNMHGFVEFDNVSF 346 M+F++IPRA ASA+RINEVLDM+ EI DP N G+VEF++VSF Sbjct: 307 MVFIMIPRAQASAVRINEVLDMESEIVDPKKPLLNE-----------NEGGYVEFNDVSF 355 Query: 347 SYPGAEQPALAGISFSAKPXXXXXXXXXXXXXXXXXXXMIPRFYDVSEGAVRVDGVDVRE 406 SYPGAEQ A++ ISFSAKP MIPRFYDV+ G+V VDG+DVRE Sbjct: 356 SYPGAEQEAISNISFSAKPGEVTAIIGGTGSGKSTLINMIPRFYDVTSGSVLVDGIDVRE 415 Query: 407 MTQEELRSKIGYIPQKAVLFTGTINENIRYGKEEATEEEVIHAAKIAQAYDFVTAMKDGF 466 M+QE +R+KIG++PQK VLF+GTI ENI+YGK++A+ EE+ HAA++AQA DF+ M DG+ Sbjct: 416 MSQESIRAKIGFVPQKTVLFSGTIAENIKYGKDDASMEEIKHAAEVAQATDFINGMDDGY 475 Query: 467 NSEISQGGGNVSGGQKQRLSIARALVRKPEVYLFDDSFSALDFKTDAKLRAALKGETTES 526 I+QGG NVSGGQKQRLSIARALVRKPE+Y+FDDSFSALDFKTDA+LRAALK ET +S Sbjct: 476 EHLIAQGGTNVSGGQKQRLSIARALVRKPEIYIFDDSFSALDFKTDARLRAALKKETLKS 535 Query: 527 TVIIVAQRVSTVMDADRIIVLDEGQIAGMGTHRELMDNSEVYREIVSSQLSEEEIA 582 TVI+VAQRV+TVMDADRIIVLDEG+IAG+GTH+EL+++ +VY EIVSSQLSEEE++ Sbjct: 536 TVILVAQRVATVMDADRIIVLDEGKIAGIGTHKELLNSCKVYSEIVSSQLSEEELS 591 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.137 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,743,567,407 Number of extensions: 99342973 Number of successful extensions: 440818 Number of sequences better than 1.0e-05: 37797 Number of HSP's gapped: 413503 Number of HSP's successfully gapped: 40284 Length of query: 582 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 441 Effective length of database: 1,732,333,088 Effective search space: 763958891808 Effective search space used: 763958891808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 134 (56.2 bits)