BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0008.p (343 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4L8.1 B3K4L8_9BACI Ribonucleoside-diphosphate reductase EC=1.... 665 0.0 B1YKU2.1 B1YKU2_EXIS2 Ribonucleoside-diphosphate reductase EC=1.... 375 e-102 C4L4U4.1 C4L4U4_EXISA Ribonucleoside-diphosphate reductase EC=1.... 370 e-100 Q9KFH7.1 RIR2_BACHD Ribonucleoside-diphosphate reductase subunit... 362 2e-98 C5D6H6.1 C5D6H6_9BACI Ribonucleoside-diphosphate reductase EC=1.... 346 1e-93 >B3K4L8.1 B3K4L8_9BACI Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 343 Score = 665 bits (1716), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/343 (91%), Positives = 329/343 (95%) Query: 1 MQLQKIFNTEAPNQSTRIIDGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKDA 60 MQ+QKIFNTEAPN+STR+I+GECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKDA Sbjct: 1 MQMQKIFNTEAPNRSTRVIEGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKDA 60 Query: 61 QQFPLLEAEEQRVFKINIGLLAVLDSMQTMFVGDVKRYFTDSSLEAISAIIGQQEVVHNQ 120 QQFP L+ EEQR FKINI LLAVLDSMQTMFV DVKRYFTDSSLEAISAIIGQQEVVHNQ Sbjct: 61 QQFPRLDPEEQRTFKINISLLAVLDSMQTMFVSDVKRYFTDSSLEAISAIIGQQEVVHNQ 120 Query: 121 SYSYVLSSIVSESEQKEIFEYWKHDPVLLERNQFISDIYQEFRDAPSKETFFRAMVADLI 180 SYSYVLSSIVSE EQKEIFEYWKHDPVLLERNQFIS+IYQ FRD PS ++FF AMVADLI Sbjct: 121 SYSYVLSSIVSEQEQKEIFEYWKHDPVLLERNQFISNIYQNFRDNPSPQSFFEAMVADLI 180 Query: 181 LEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLVDFPELNTK 240 LEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLL DFPELNTK Sbjct: 181 LEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLKDFPELNTK 240 Query: 241 ENMDYVYRTIDRAVELETNWGYYTLTNVRGIDMNELSDYIKYTANKRLTLMGLEKAYSGV 300 EN+DY+YRTIDRAVELETNW +YTL+NVRGID+NELSDYIKY AN+R+T+MGLEKAY GV Sbjct: 241 ENIDYLYRTIDRAVELETNWAHYTLSNVRGIDLNELSDYIKYIANRRITMMGLEKAYEGV 300 Query: 301 DVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 DVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL Sbjct: 301 DVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 >B1YKU2.1 B1YKU2_EXIS2 Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 347 Score = 375 bits (963), Expect = e-102, Method: Compositional matrix adjust. Identities = 183/345 (53%), Positives = 249/345 (72%), Gaps = 3/345 (0%) Query: 2 QLQKI--FNTEAPNQSTRIIDGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKD 59 QLQKI + PN++T II GE S I+NWNDI P Y +YK LL N WI DEI MSKD Sbjct: 3 QLQKIKLLDARHPNRATAIIGGETSSIVNWNDIAYPQFYSIYKQLLSNFWIPDEISMSKD 62 Query: 60 AQQFPLLEAEEQRVFKINIGLLAVLDSMQTMFVGDVKRYFTDSSLEAISAIIGQQEVVHN 119 QQ+ L EQ FK IGLL++LDS+QT ++ + + +D+S+ AI AI+ QQEVVHN Sbjct: 63 MQQWNQLSEREQDAFKRIIGLLSILDSVQTRYILESAMFTSDASIHAILAIVAQQEVVHN 122 Query: 120 QSYSYVLSSIVSESEQKEIFEYWKHDPVLLERNQFISDIYQEFRDAPSKETFFRAMVADL 179 QSYSYVLSS+V SEQ IF+ K D ++++RN FI D+Y++F++ + E F +++VA + Sbjct: 123 QSYSYVLSSLVPLSEQNRIFDIAKDDDMVMKRNAFILDLYEDFQNDRTPENFAKSLVASI 182 Query: 180 ILEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLVDFPELNT 239 +LEGI FYS FAFFYNLAR QKM+ TS MISYIQRDE QH YF +++ + +L + P+++ Sbjct: 183 VLEGINFYSGFAFFYNLARHQKMVGTSTMISYIQRDELQHSYFISQLLRAVLTEHPDIDA 242 Query: 240 KENM-DYVYRTIDRAVELETNWGYYTLTNVRGIDMNELSDYIKYTANKRLTLMGLEKAYS 298 + +VY T +RAV+LE W Y L ++ G+D++E+ DY+KY ANKRL ++GL+ Y Sbjct: 243 DGSFTKFVYATFERAVDLEIEWSEYVLRDLDGLDVSEMRDYVKYLANKRLRVIGLDDLYE 302 Query: 299 GVDVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 G D + MPWI+ +SD+++NATK+DFFE KSR+Y KV D NGFDDL Sbjct: 303 GHDEDVMPWIRAYSDDSMNATKSDFFEQKSRSYAKVTDANGFDDL 347 >C4L4U4.1 C4L4U4_EXISA Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 346 Score = 370 bits (950), Expect = e-100, Method: Compositional matrix adjust. Identities = 185/346 (53%), Positives = 248/346 (71%), Gaps = 3/346 (0%) Query: 1 MQLQKI--FNTEAPNQSTRIIDGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSK 58 M +QKI + + PN++T II GE S I+NWNDI P Y +YK LL N WI DEI MSK Sbjct: 1 MSIQKIKLLSPKHPNRATAIIGGETSSIVNWNDIAYPQFYTIYKQLLSNFWIPDEISMSK 60 Query: 59 DAQQFPLLEAEEQRVFKINIGLLAVLDSMQTMFVGDVKRYFTDSSLEAISAIIGQQEVVH 118 D QQ+P L EQ FK IGLL++LDS+QT ++ + + +DSS+ A+ A+I QQEVVH Sbjct: 61 DMQQWPQLTEREQDAFKRIIGLLSILDSVQTRYILESSMFSSDSSVHAVLAVIAQQEVVH 120 Query: 119 NQSYSYVLSSIVSESEQKEIFEYWKHDPVLLERNQFISDIYQEFRDAPSKETFFRAMVAD 178 NQSYSYVLSS+V +EQ IF K D ++++RNQFI D+Y+ FR+ P+ E F +++VA Sbjct: 121 NQSYSYVLSSLVPLAEQNRIFNIAKDDEMVMKRNQFILDLYEAFRETPNAENFAKSLVAS 180 Query: 179 LILEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLVDFPELN 238 +ILEGI FYS FA+FYNLAR QKM+ TS MISYIQRDE QH YF +++ + +L + P+++ Sbjct: 181 VILEGINFYSGFAYFYNLARHQKMVGTSTMISYIQRDEMQHSYFISQLLRAVLTENPKID 240 Query: 239 TKENMD-YVYRTIDRAVELETNWGYYTLTNVRGIDMNELSDYIKYTANKRLTLMGLEKAY 297 +VY T+ AV+LE W Y L ++ G+D++E+ DY+KY ANKRL ++GL Y Sbjct: 241 ENGQFSQFVYDTMAEAVDLEIEWCEYVLRDLDGLDVSEMRDYVKYLANKRLRVIGLNDLY 300 Query: 298 SGVDVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 G D + MPWI+ +SD++LNATK+DFFE KSR+Y KV D NGFDDL Sbjct: 301 EGFDEDVMPWIRAYSDDSLNATKSDFFEQKSRSYAKVTDANGFDDL 346 >Q9KFH7.1 RIR2_BACHD Ribonucleoside-diphosphate reductase subunit beta EC=1.17.4.1 Length = 345 Score = 362 bits (930), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 181/344 (52%), Positives = 240/344 (69%), Gaps = 3/344 (0%) Query: 1 MQLQKIFNTEAPNQSTRIIDGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKDA 60 +Q +KI++T A N ST I++G+ S +LNW+D+R Y LYK +L N W EI MS DA Sbjct: 4 LQKRKIYDTTASNASTGILNGKSSNVLNWDDVRFSWAYPLYKNMLANFWTPFEINMSHDA 63 Query: 61 QQFPLLEAEEQRVFKINIGLLAVLDSMQTMFVGDVKRYFTDSSLEAISAIIGQQEVVHNQ 120 +QFP L EQ FK IGLLA LDS+QT + Y TDSSL A+ +++ QEVVHNQ Sbjct: 64 KQFPTLTETEQEAFKKIIGLLAFLDSVQTDYSMRAAEYLTDSSLAALMSVLSFQEVVHNQ 123 Query: 121 SYSYVLSSIVSESEQKEIFEYWKHDPVLLERNQFISDIYQEFRDAPSKETFFRAMVADLI 180 SYSYVLSS+V ++ Q EIFEYWKHD VL ERN+FI D Y++F D P+ +TF ++V D+I Sbjct: 124 SYSYVLSSLVPKATQDEIFEYWKHDDVLKERNEFIIDGYEKFVDNPTPKTFLESIVYDVI 183 Query: 181 LEGIFFYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLVDFPELNTK 240 LEG+ FYS FAFFYNLAR+QKM++TS MI+YI RDE H Y F +FK+LLV+FPELNT+ Sbjct: 184 LEGLNFYSGFAFFYNLARNQKMVSTSTMINYINRDEQLHVYLFTNIFKELLVEFPELNTE 243 Query: 241 ENMDYVYRTIDRAVELETNWGYYTLTN-VRGIDMNELSDYIKYTANKRLTLMGLEKAYSG 299 E +V T+ +A +LE +W Y + + + GI+ ++ YI + ANKR +G+EK Y Sbjct: 244 ETKTFVKTTLMKAADLEKDWFRYIIGDKIPGINPEDMETYISFIANKRAVQLGMEKPYPE 303 Query: 300 VDVNCMPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 + N M WI+ + D +N+ K+DFFE KSR Y KV DNGFD+L Sbjct: 304 IKHNPMKWIRAYED--VNSGKSDFFEQKSRQYAKVSADNGFDEL 345 >C5D6H6.1 C5D6H6_9BACI Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 346 Score = 346 bits (888), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 171/339 (50%), Positives = 237/339 (69%), Gaps = 3/339 (0%) Query: 6 IFNTEAPNQSTRIIDGECSGILNWNDIRMPHMYKLYKVLLLNHWIADEIPMSKDAQQFPL 65 I + EAPN+STRII+G+ S +LNW+DI P Y YK +L N W EI MS+D +QFP Sbjct: 10 IMDPEAPNRSTRIINGKSSNVLNWDDIAYPWAYAKYKRMLANFWTPFEINMSQDVKQFPN 69 Query: 66 LEAEEQRVFKINIGLLAVLDSMQTMFVGDVKRYFTDSSLEAISAIIGQQEVVHNQSYSYV 125 L EQ F IGLLA+LDS+QT + G V Y TDSS+ A+ ++ QQEV+HN SYSYV Sbjct: 70 LTEREQDAFLKIIGLLALLDSIQTDYAGRVADYITDSSINALMIMLAQQEVIHNHSYSYV 129 Query: 126 LSSIVSESEQKEIFEYWKHDPVLLERNQFISDIYQEFRDAPSKETFFRAMVADLILEGIF 185 LSS+V +S+Q E+FE+W+++P+L +RN F+++ Y+ F + P+ E +++V D+ILEG+F Sbjct: 130 LSSLVPKSKQDEVFEFWRNEPILRKRNDFVTNGYKAFAENPNVENLLKSIVYDVILEGLF 189 Query: 186 FYSTFAFFYNLARDQKMMATSQMISYIQRDENQHCYFFAEVFKQLLVDFPELNTKENMDY 245 FYS FAFFYNLAR+QKM+ATS MI+YI RDE+ H FA++FK++L ++PE NT E + Sbjct: 190 FYSGFAFFYNLARNQKMVATSTMINYINRDEHIHVDLFAKIFKEVLNEYPEYNTPELAQF 249 Query: 246 VYRTIDRAVELETNWGYYTLTN-VRGIDMNELSDYIKYTANKRLTLMGLEKAYSGVDVNC 304 V T +A +LE W Y + N + GIDM++LS YIK+ AN R +G ++ + G N Sbjct: 250 VRETFIKAAKLEIEWANYIIGNDIDGIDMHDLSAYIKFYANVRAHQLGFDRPFDGYRTNP 309 Query: 305 MPWIKPFSDEALNATKTDFFEAKSRNYGKVGDDNGFDDL 343 + WIK + E ++ K+DFFE KSR Y KV DNGFD+L Sbjct: 310 LRWIKAY--EEVDLGKSDFFEQKSRQYTKVNIDNGFDEL 346 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,916,633,656 Number of extensions: 75994429 Number of successful extensions: 200527 Number of sequences better than 1.0e-05: 1997 Number of HSP's gapped: 196728 Number of HSP's successfully gapped: 1998 Length of query: 343 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 207 Effective length of database: 1,779,438,163 Effective search space: 368343699741 Effective search space used: 368343699741 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 131 (55.1 bits)