BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0006.p (781 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4L9.1 B3K4L9_9BACI Ribonucleoside-diphosphate reductase EC=1.... 1413 0.0 C5D6H7.1 C5D6H7_9BACI Ribonucleoside-diphosphate reductase, alph... 942 0.0 B4BI75.1 B4BI75_9BACI Ribonucleoside-diphosphate reductase EC=1.... 920 0.0 A4ILG9.1 A4ILG9_GEOTN Ribonucleoside-diphosphate reductase EC=1.... 920 0.0 Q5L1I4.1 Q5L1I4_GEOKA Ribonucleoside-diphosphate reductase EC=1.... 919 0.0 >B3K4L9.1 B3K4L9_9BACI Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 777 Score = 1413 bits (3658), Expect = 0.0, Method: Compositional matrix adjust. Identities = 666/777 (85%), Positives = 718/777 (92%) Query: 5 MPQLVVKPDNRQLAFDEIRLSVYADRILKGLDHLSKETLLRGVQSKLRREEVSGEEISNA 64 MPQLVVKP+NRQLAFDEIRLSVYADR LKGLD L KE LLRGV +KLR E+V+GEEIS+A Sbjct: 1 MPQLVVKPNNRQLAFDEIRLSVYADRTLKGLDMLDKERLLRGVNAKLRGEQVTGEEISSA 60 Query: 65 FTMSALELVTKEEPDWKFAAARSLLTSLYKKAAVNRRYKAYPDEPYGELYPLITDLVKKG 124 FTMSALELVTKEEP+WKFAAARS LTSLYKKAA NRRYKAYP+EPYG YPLIT+LV+KG Sbjct: 61 FTMSALELVTKEEPNWKFAAARSFLTSLYKKAATNRRYKAYPEEPYGAFYPLITELVQKG 120 Query: 125 IYREELLSHYTKEQIEELGGCIDYTRDLLFDYIGLLTLSDRYLAHDFDGRVMELPQERYM 184 IYRE+LL+ YTKEQIEELG CID +RDLLFDYIGLLTL++RYLA+DFDGRVMELPQERYM Sbjct: 121 IYREDLLTSYTKEQIEELGECIDPSRDLLFDYIGLLTLAERYLANDFDGRVMELPQERYM 180 Query: 185 IIAMFLMHTEPEEKRLELVKEAYWAMSNIYMTAATPTMSNAGKKVAGQLSSCFIDTVDDS 244 +IAMFLMH EP +KRL+LVKEAYWAMSN+YMTAATPTMSNAGKKVAGQLSSCFIDTVDDS Sbjct: 181 VIAMFLMHNEPADKRLDLVKEAYWAMSNLYMTAATPTMSNAGKKVAGQLSSCFIDTVDDS 240 Query: 245 LEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNTAVSVD 304 LEGIFDSNTD+ARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNTAVSVD Sbjct: 241 LEGIFDSNTDIARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNTAVSVD 300 Query: 305 QLGTRKGAVAVYLDVFHKDILAFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVEARGHW 364 QLGTRKGA+AVYLDVFHKDIL+FLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVEAR W Sbjct: 301 QLGTRKGAIAVYLDVFHKDILSFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVEAREEW 360 Query: 365 NLFCPHEVKKVMGWKDAKGRALGLEDFYDEQLGQGSFREKYAEATANLELSRITVPAIDI 424 +LFCPHEVKK+MGWKD GR LGLEDFYD G+G FR+KYAEA AN L RITV AIDI Sbjct: 361 SLFCPHEVKKIMGWKDENGRPLGLEDFYDHTQGEGEFRQKYAEAVANPLLPRITVQAIDI 420 Query: 425 MKRIMKSQLETGTPYMFYRDTVNRSNPNRHQGMVFSSNLCTEIMQNQSATVIESEELVTK 484 MKRIMKSQLETGTPYMFYRDTVNR+NPN GM++SSNLCTEIMQNQS TV+E EELVTK Sbjct: 421 MKRIMKSQLETGTPYMFYRDTVNRANPNSAHGMIYSSNLCTEIMQNQSPTVVEQEELVTK 480 Query: 485 DGQTRIVISKVPGDFVVCNLNSIHLARAIPAGVLERLVPIQVRMLDNVIDINNIEVLQAQ 544 DGQTRIVISK+PGDFVVCNLNSIHLARA+PAGVLERLVPIQVRMLDNVIDINNIEVLQAQ Sbjct: 481 DGQTRIVISKIPGDFVVCNLNSIHLARAVPAGVLERLVPIQVRMLDNVIDINNIEVLQAQ 540 Query: 545 YTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVEYNNHLYEHINYLVVRSSMELAREKGR 604 YTNSQYRAVGLGTFGLHHLLALEGIRWESDEAV YN++LYEHINYL+V+SSMELA+EKG Sbjct: 541 YTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVAYNDNLYEHINYLLVKSSMELAKEKGH 600 Query: 605 YPKFAGSDWETGAYFTSRGYTSGEQEGKYVTTEQWRELQEQVAADGVRNAWMFAIAPNXX 664 YPKF GSDWE+G YFT RGYT GE EGK+VTTEQWRELQ++V A+GVRNAW+FAIAPN Sbjct: 601 YPKFKGSDWESGEYFTFRGYTDGEHEGKFVTTEQWRELQQEVQANGVRNAWLFAIAPNGS 660 Query: 665 XXXXXXXXXXXDPLYELLSYEEKTTYKIANPAPDLSEKTIWYYKTAFLIDQNWSIRMASA 724 DPLYELLSYEEKTTYK+ANPAPDLSEKTIWYYKTAFLIDQ+WSI+MA+A Sbjct: 661 TSIIAGSTASIDPLYELLSYEEKTTYKVANPAPDLSEKTIWYYKTAFLIDQHWSIKMAAA 720 Query: 725 RQRHVDQGQSFNLYVTPDIKATDFLNLHLNAWKGGLKSTYYVRSRALTIEECESCAS 781 RQRHVDQ QSFNLYV PDI+A++FL LHL+AWK G+KSTYYVRSRALTIEECESCAS Sbjct: 721 RQRHVDQAQSFNLYVRPDIRASEFLELHLHAWKAGIKSTYYVRSRALTIEECESCAS 777 >C5D6H7.1 C5D6H7_9BACI Ribonucleoside-diphosphate reductase, alpha subunit EC=1.17.4.1 Length = 761 Score = 942 bits (2435), Expect = 0.0, Method: Compositional matrix adjust. Identities = 466/779 (59%), Positives = 568/779 (72%), Gaps = 30/779 (3%) Query: 8 LVVKPDNRQL-AFDEIRLSVYADRILKGLDHLSK----ETLLRGVQSKLRREEVSGEEIS 62 +++ +N Q F RL + I K HL E ++R ++SK + +S E+I+ Sbjct: 8 IIITSENGQTKPFSRERLISFIRNITKDYPHLQTDDYMERIIRIIESK---DTLSAEQIT 64 Query: 63 NAFTMSALELVTKEEPDWKFAAARSLLTSLYKKAAVNRRYKAYPDEPYGELYPLITDLVK 122 N + L +++ EP+W F A L LYK+AA R Y A + YG LY LIT LV Sbjct: 65 NYLILEGLSYISEAEPEWTFVCAHIYLQKLYKEAAKQRGYDA--KQRYGSLYELITTLVS 122 Query: 123 KGIYREELLSHYTKEQIEELGGCIDYTRDLLFDYIGLLTLSDRYLAHDFDGRVMELPQER 182 KG+Y LL +Y+KE+I ELG ID +D LF YIGL TL+DRYLA D+D + ELPQER Sbjct: 123 KGVYDRSLLDNYSKEEINELGKLIDPDKDKLFTYIGLRTLADRYLARDYDRNLYELPQER 182 Query: 183 YMIIAMFLMHTEPEEKRLELVKEAYWAMSNIYMTAATPTMSNAGKKVAGQLSSCFIDTVD 242 ++IIAM LM EP+ +R ++EAYWA+SN+YMT ATPT++NAGK GQLSSCFIDTVD Sbjct: 183 FLIIAMTLMAKEPKHRRFTFIQEAYWALSNLYMTVATPTLANAGKSY-GQLSSCFIDTVD 241 Query: 243 DSLEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNTAVS 302 DSL+GI+DSNTD+A LSK GGGIGVYLGK+R+RGSDIRG K SSGVIPW++QLNNTAVS Sbjct: 242 DSLQGIYDSNTDIANLSKSGGGIGVYLGKIRSRGSDIRGFKGVSSGVIPWMKQLNNTAVS 301 Query: 303 VDQLGTRKGAVAVYLDVFHKDILAFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVEARG 362 VDQLG RKGA++VYLDV+HKDI AFLD KLNNGDERMR HD+F GVC+PDLFME VE RG Sbjct: 302 VDQLGQRKGAISVYLDVWHKDIFAFLDAKLNNGDERMRTHDLFTGVCIPDLFMEQVEKRG 361 Query: 363 HWNLFCPHEVKKVMGWKDAKGRALGLEDFYDEQLGQGSFREKYAEATANLELSRITVPAI 422 W LF PHEV+KVMG LEDFYDE+ G GSFREKY + LS+ VPAI Sbjct: 362 DWYLFDPHEVRKVMG--------FSLEDFYDEEKGSGSFREKYWQCVQEERLSKEKVPAI 413 Query: 423 DIMKRIMKSQLETGTPYMFYRDTVNRSNPNRHQGMVFSSNLCTEIMQNQSATVIESEELV 482 +IMK IM+SQLE+GTP+MFYRD VNR NPN H GM++ SNLCTEI QNQS TV+E + Sbjct: 414 EIMKSIMRSQLESGTPFMFYRDEVNRKNPNAHLGMIYCSNLCTEIAQNQSPTVVEKQ--Y 471 Query: 483 TKDGQTRIVISKVPGDFVVCNLNSIHLARAIPAGVLERLVPIQVRMLDNVIDINNIEVLQ 542 TKDG +I+I K+PGDFVVCNL+SI+LARA+ VLERL+PIQ+RMLDNVID+NNI VLQ Sbjct: 472 TKDG--KIIIEKIPGDFVVCNLSSINLARAVTDDVLERLIPIQMRMLDNVIDLNNIPVLQ 529 Query: 543 AQYTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVEYNNHLYEHINYLVVRSSMELAREK 602 A++TN +YRAVGLGTFG HHLLAL+GIRWESDEAVEY + LYE I YL +++SMELA+EK Sbjct: 530 AKFTNQKYRAVGLGTFGWHHLLALKGIRWESDEAVEYADKLYEKIAYLAIKASMELAKEK 589 Query: 603 GRYPKFAGSDWETGAYFTSRGYTSGEQEGKYVTTEQWRELQEQVAADGVRNAWMFAIAPN 662 G YP F GSDW+TGAYF RGY E+ W L+EQVA G+RN ++ AIAPN Sbjct: 590 GSYPAFPGSDWQTGAYFDKRGYHRTEE-------FDWDALKEQVAKHGMRNGYVMAIAPN 642 Query: 663 XXXXXXXXXXXXXDPLYELLSYEEKTTYKIANPAPDLSEKTIWYYKTAFLIDQNWSIRMA 722 DP++ + EEK YKI PDL+ +T WYYK+A+ IDQ+WSI+ Sbjct: 643 ASTSIIAGSTASIDPIFLKVYAEEKKDYKIPVTVPDLNAETTWYYKSAYHIDQHWSIKQN 702 Query: 723 SARQRHVDQGQSFNLYVTPDIKATDFLNLHLNAWKGGLKSTYYVRSRALTIEECESCAS 781 +ARQRH+DQ SFN YV IKA + L+LHL AWK GLK+TYYVRS + TI+ECESCAS Sbjct: 703 AARQRHIDQAISFNFYVLNTIKAKELLDLHLTAWKSGLKTTYYVRSTSSTIDECESCAS 761 >B4BI75.1 B4BI75_9BACI Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 760 Score = 920 bits (2379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 454/783 (57%), Positives = 566/783 (72%), Gaps = 25/783 (3%) Query: 1 MYELMPQLVVKPDNRQLAFDEIRLSVYADRILKGLDHLSKETLLRGVQSKLRREE-VSGE 59 M + +VV ++ + + ++ G LS E V L R+E V+ + Sbjct: 1 MTAVTKSIVVDDQGKEKSLSRREFAALIEQATAGFVRLSLEEYEERVWQLLSRKEFVTVD 60 Query: 60 EISNAFTMSALELVTKEEPDWKFAAARSLLTSLYKKAAVNRRYKAYPDEPYGELYPLITD 119 ++ + L +++EEP+W F AR L +Y++AA R Y A E YG+ Y LI Sbjct: 61 QLYQTAILEGLSYISEEEPEWTFVCARLYLRMMYREAARQRGYDA--RERYGDFYSLIVS 118 Query: 120 LVKKGIYREELLSHYTKEQIEELGGCIDYTRDLLFDYIGLLTLSDRYLAHDFDGRVMELP 179 L ++G+Y LL YTKE+IE G +D +DLLF YIGL TL+DRYLA D++ R+ ELP Sbjct: 119 LTEQGVYSPLLLERYTKEEIETAGSFLDPDKDLLFTYIGLRTLADRYLARDYERRLYELP 178 Query: 180 QERYMIIAMFLMHTEPEEKRLELVKEAYWAMSNIYMTAATPTMSNAGKKVAGQLSSCFID 239 QER++IIAM LM EP ++RLELVKEAYWA+SN+YMT ATPT++NAGK GQLSSCF+D Sbjct: 179 QERFLIIAMTLMVNEPPKRRLELVKEAYWALSNLYMTVATPTLANAGKSY-GQLSSCFVD 237 Query: 240 TVDDSLEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNT 299 TVDDSL+ I+DSNTD+A LSK GGGIGVYLGK+R+RGSDIRG K SSGVIPW++QLNNT Sbjct: 238 TVDDSLQAIYDSNTDIANLSKSGGGIGVYLGKIRSRGSDIRGFKGVSSGVIPWMKQLNNT 297 Query: 300 AVSVDQLGTRKGAVAVYLDVFHKDILAFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVE 359 AVSVDQLG RKGA++VYLDV+HKDI AFLD +LNNGDER+R HD+F GVC+PDLFME VE Sbjct: 298 AVSVDQLGQRKGAISVYLDVWHKDIFAFLDARLNNGDERLRTHDLFTGVCIPDLFMEQVE 357 Query: 360 ARGHWNLFCPHEVKKVMGWKDAKGRALGLEDFYDEQLGQGSFREKYAEATANLELSRITV 419 RG W LF PHEV+KVMG LEDFYDE+ G+GSFREKY + LS+ V Sbjct: 358 QRGDWYLFDPHEVRKVMG--------FSLEDFYDEEKGRGSFREKYWQCVNEPRLSKEKV 409 Query: 420 PAIDIMKRIMKSQLETGTPYMFYRDTVNRSNPNRHQGMVFSSNLCTEIMQNQSATVIESE 479 PAI++MK IM+SQLE+GTP+MFYRD VNR NPNRH GM++ SNLCTEI QNQS TV ++ Sbjct: 410 PAIEVMKSIMRSQLESGTPFMFYRDEVNRQNPNRHLGMIYCSNLCTEIAQNQSPTV--TK 467 Query: 480 ELVTKDGQTRIVISKVPGDFVVCNLNSIHLARAIPAGVLERLVPIQVRMLDNVIDINNIE 539 + KDG I+I K+PGDFVVCNL+SI+LARA+ GVLERL+PIQ+RMLDNVID+NNI Sbjct: 468 QQYVKDGT--IIIEKIPGDFVVCNLSSINLARAVTDGVLERLIPIQLRMLDNVIDLNNIP 525 Query: 540 VLQAQYTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVEYNNHLYEHINYLVVRSSMELA 599 VLQA TN +YRAVGLGTFG HHLLAL+GIRWES+EAV Y + LYE I YLV+++SMELA Sbjct: 526 VLQASLTNKKYRAVGLGTFGWHHLLALKGIRWESEEAVRYTDELYETIAYLVIQASMELA 585 Query: 600 REKGRYPKFAGSDWETGAYFTSRGYTS-GEQEGKYVTTEQWRELQEQVAADGVRNAWMFA 658 +EKG YP F+GSDW+TGAYF RGY + GE++ W L+ +VA G+RN ++ A Sbjct: 586 KEKGSYPGFSGSDWQTGAYFERRGYKNHGERD--------WDRLKREVARYGMRNGYLMA 637 Query: 659 IAPNXXXXXXXXXXXXXDPLYELLSYEEKTTYKIANPAPDLSEKTIWYYKTAFLIDQNWS 718 +APN DP++ + EEK YKI PDL+E+T WYYK+A+ IDQ WS Sbjct: 638 VAPNASTSIIAGSTASIDPIFRKVYAEEKKDYKIPVTVPDLNEQTTWYYKSAYYIDQRWS 697 Query: 719 IRMASARQRHVDQGQSFNLYVTPDIKATDFLNLHLNAWKGGLKSTYYVRSRALTIEECES 778 IR +ARQ H+DQ SFN YV IKA + L LHL AWK GLK+TYYVRS + T+EEC++ Sbjct: 698 IRQNAARQHHIDQAISFNFYVMNTIKAKELLELHLTAWKSGLKTTYYVRSTSGTMEECDA 757 Query: 779 CAS 781 CAS Sbjct: 758 CAS 760 >A4ILG9.1 A4ILG9_GEOTN Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 785 Score = 920 bits (2378), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/783 (57%), Positives = 566/783 (72%), Gaps = 25/783 (3%) Query: 1 MYELMPQLVVKPDNRQLAFDEIRLSVYADRILKGLDHLSKETLLRGVQSKLRREE-VSGE 59 M + +VV ++ + + ++ G LS E V L R+E V+ + Sbjct: 26 MTAVTKSIVVDDQGKEKSLSRREFAALIEQATAGFVRLSLEEYEERVWQLLSRKEFVTVD 85 Query: 60 EISNAFTMSALELVTKEEPDWKFAAARSLLTSLYKKAAVNRRYKAYPDEPYGELYPLITD 119 ++ + L +++EEP+W F AR L +Y++AA R Y A E YG+ Y LI Sbjct: 86 QLYQTAILEGLSYISEEEPEWTFVCARLYLRMMYREAARQRGYDA--RERYGDFYSLIVS 143 Query: 120 LVKKGIYREELLSHYTKEQIEELGGCIDYTRDLLFDYIGLLTLSDRYLAHDFDGRVMELP 179 L ++G+Y LL YTKE+IE G +D +DLLF YIGL TL+DRYLA D++ R+ ELP Sbjct: 144 LTEQGVYSPLLLERYTKEEIETAGSFLDPDKDLLFTYIGLRTLADRYLARDYERRLYELP 203 Query: 180 QERYMIIAMFLMHTEPEEKRLELVKEAYWAMSNIYMTAATPTMSNAGKKVAGQLSSCFID 239 QER++IIAM LM EP ++RLELVKEAYWA+SN+YMT ATPT++NAGK GQLSSCF+D Sbjct: 204 QERFLIIAMTLMVNEPPKRRLELVKEAYWALSNLYMTVATPTLANAGKSY-GQLSSCFVD 262 Query: 240 TVDDSLEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNT 299 TVDDSL+ I+DSNTD+A LSK GGGIGVYLGK+R+RGSDIRG K SSGVIPW++QLNNT Sbjct: 263 TVDDSLQAIYDSNTDIANLSKSGGGIGVYLGKIRSRGSDIRGFKGVSSGVIPWMKQLNNT 322 Query: 300 AVSVDQLGTRKGAVAVYLDVFHKDILAFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVE 359 AVSVDQLG RKGA++VYLDV+HKDI AFLD +LNNGDER+R HD+F GVC+PDLFME VE Sbjct: 323 AVSVDQLGQRKGAISVYLDVWHKDIFAFLDARLNNGDERLRTHDLFTGVCIPDLFMEQVE 382 Query: 360 ARGHWNLFCPHEVKKVMGWKDAKGRALGLEDFYDEQLGQGSFREKYAEATANLELSRITV 419 RG W LF PHEV+KVMG LEDFYDE+ G+GSFREKY + + LS+ V Sbjct: 383 QRGDWYLFDPHEVRKVMG--------FSLEDFYDEEKGRGSFREKYWQCVNDSRLSKEKV 434 Query: 420 PAIDIMKRIMKSQLETGTPYMFYRDTVNRSNPNRHQGMVFSSNLCTEIMQNQSATVIESE 479 PAI++MK IM+SQLE+GTP+MFYRD VNR NPNRH GM++ SNLCTEI QNQS TV ++ Sbjct: 435 PAIEVMKSIMRSQLESGTPFMFYRDEVNRQNPNRHLGMIYCSNLCTEIAQNQSPTV--TK 492 Query: 480 ELVTKDGQTRIVISKVPGDFVVCNLNSIHLARAIPAGVLERLVPIQVRMLDNVIDINNIE 539 + KDG I+I K+PGDFVVCNL+SI+LARA+ GV ERL+PIQ+RMLDNVID+NNI Sbjct: 493 QQYVKDGT--IIIEKIPGDFVVCNLSSINLARAVTDGVFERLIPIQLRMLDNVIDLNNIP 550 Query: 540 VLQAQYTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVEYNNHLYEHINYLVVRSSMELA 599 VLQA TN +YRAVGLGTFG HHLLAL+GIRWES+EAV Y + LYE I YL +++SMELA Sbjct: 551 VLQASLTNKKYRAVGLGTFGWHHLLALKGIRWESEEAVRYTDELYETIAYLAIQASMELA 610 Query: 600 REKGRYPKFAGSDWETGAYFTSRGYTS-GEQEGKYVTTEQWRELQEQVAADGVRNAWMFA 658 +EKG YP F+GSDW+TGAYF RGY + GE++ W L+ +VA G+RN ++ A Sbjct: 611 KEKGSYPGFSGSDWQTGAYFERRGYKNHGERD--------WDRLKREVARYGMRNGYLMA 662 Query: 659 IAPNXXXXXXXXXXXXXDPLYELLSYEEKTTYKIANPAPDLSEKTIWYYKTAFLIDQNWS 718 +APN DP++ + EEK YKI PDL+E+T WYYK+A+ IDQ WS Sbjct: 663 VAPNASTSIIAGSTASIDPIFRKVYAEEKKDYKIPVTVPDLNEQTTWYYKSAYYIDQRWS 722 Query: 719 IRMASARQRHVDQGQSFNLYVTPDIKATDFLNLHLNAWKGGLKSTYYVRSRALTIEECES 778 IR +ARQRH+DQ SFN YV IKA + L LHL AWK GLK+TYYVRS + T+EEC++ Sbjct: 723 IRQNAARQRHIDQAISFNFYVMNTIKAKELLELHLTAWKSGLKTTYYVRSTSGTMEECDA 782 Query: 779 CAS 781 CAS Sbjct: 783 CAS 785 >Q5L1I4.1 Q5L1I4_GEOKA Ribonucleoside-diphosphate reductase EC=1.17.4.1 Length = 785 Score = 919 bits (2376), Expect = 0.0, Method: Compositional matrix adjust. Identities = 455/783 (58%), Positives = 566/783 (72%), Gaps = 25/783 (3%) Query: 1 MYELMPQLVVKPDNRQLAFDEIRLSVYADRILKGLDHLSKETLLRGVQSKL-RREEVSGE 59 M L +++ + ++F + + + G LS + + V L R+E V+ E Sbjct: 26 MTALTKMIIIDDQGKPVSFSREEFASLIGQAVAGFGRLSLDEYVERVWQLLSRKESVTVE 85 Query: 60 EISNAFTMSALELVTKEEPDWKFAAARSLLTSLYKKAAVNRRYKAYPDEPYGELYPLITD 119 ++ + L + ++EPDW F AR L LY++AA R Y A E YG+ Y LI Sbjct: 86 QLHQTAILEGLSYIDEDEPDWTFVCARLYLQQLYREAARQRGYDA--RERYGDFYSLIVS 143 Query: 120 LVKKGIYREELLSHYTKEQIEELGGCIDYTRDLLFDYIGLLTLSDRYLAHDFDGRVMELP 179 L ++G+Y LL YTKE+IE G +D +DLLF YIGL TL+DRYLA D++ R+ ELP Sbjct: 144 LTEQGVYSPLLLERYTKEEIETAGSFLDPGKDLLFTYIGLRTLADRYLARDYERRLYELP 203 Query: 180 QERYMIIAMFLMHTEPEEKRLELVKEAYWAMSNIYMTAATPTMSNAGKKVAGQLSSCFID 239 QER+++IAM LM EP ++RLELVKEAYWA+SN+YMT ATPT++NAGK GQLSSCF+D Sbjct: 204 QERFLVIAMTLMVNEPPKRRLELVKEAYWALSNLYMTVATPTLANAGKSY-GQLSSCFVD 262 Query: 240 TVDDSLEGIFDSNTDVARLSKMGGGIGVYLGKVRARGSDIRGHKNTSSGVIPWIRQLNNT 299 TVDDSL+GI+DSNTD+A LSK GGGIGVYLGK+R+RGSDI+G K SSGVIPW++QLNNT Sbjct: 263 TVDDSLQGIYDSNTDIANLSKSGGGIGVYLGKIRSRGSDIKGFKGVSSGVIPWMKQLNNT 322 Query: 300 AVSVDQLGTRKGAVAVYLDVFHKDILAFLDLKLNNGDERMRAHDVFHGVCLPDLFMEAVE 359 AVSVDQLG RKGA++VYLDV+HKDI AFLD +LNNGDER+R HD+F GVC+PDLFME VE Sbjct: 323 AVSVDQLGQRKGAISVYLDVWHKDIFAFLDARLNNGDERLRTHDLFTGVCIPDLFMEQVE 382 Query: 360 ARGHWNLFCPHEVKKVMGWKDAKGRALGLEDFYDEQLGQGSFREKYAEATANLELSRITV 419 RG W LF PHEV+KVMG+ LEDFYDE+ G GSFREKY + LS+ V Sbjct: 383 QRGDWYLFDPHEVRKVMGFS--------LEDFYDEEKGCGSFREKYWQCVNEPRLSKEKV 434 Query: 420 PAIDIMKRIMKSQLETGTPYMFYRDTVNRSNPNRHQGMVFSSNLCTEIMQNQSATVIESE 479 PAI++MK IM+SQLE+GTP+MFYRD VNR NPNRH GM++ SNLCTEI QNQS TV++ + Sbjct: 435 PAIEVMKSIMRSQLESGTPFMFYRDEVNRQNPNRHLGMIYCSNLCTEIAQNQSPTVMKRQ 494 Query: 480 ELVTKDGQTRIVISKVPGDFVVCNLNSIHLARAIPAGVLERLVPIQVRMLDNVIDINNIE 539 KDG I+I K+PGDFVVCNL+SI+LARA+ GVL RL+PIQ+RMLDNVID+NNI Sbjct: 495 --YVKDGM--IIIEKIPGDFVVCNLSSINLARAVTDGVLARLIPIQMRMLDNVIDLNNIP 550 Query: 540 VLQAQYTNSQYRAVGLGTFGLHHLLALEGIRWESDEAVEYNNHLYEHINYLVVRSSMELA 599 VLQA TN +YRAVGLGTFG HHLLAL+GIRWES+EAV Y + LYE I YL +++SMELA Sbjct: 551 VLQAGLTNEKYRAVGLGTFGWHHLLALKGIRWESEEAVRYADELYETIAYLAIQASMELA 610 Query: 600 REKGRYPKFAGSDWETGAYFTSRGYTS-GEQEGKYVTTEQWRELQEQVAADGVRNAWMFA 658 +EKG YP F GSDW+TGAYF RGY S GE + W L++ VA G+RN ++ A Sbjct: 611 KEKGSYPAFPGSDWQTGAYFERRGYQSHGELD--------WDRLKQDVARYGMRNGYIMA 662 Query: 659 IAPNXXXXXXXXXXXXXDPLYELLSYEEKTTYKIANPAPDLSEKTIWYYKTAFLIDQNWS 718 IAPN DP++ + EEK YKI PDL+E+T WYYK+A+ IDQ WS Sbjct: 663 IAPNASTSIIAGSTASIDPIFLKVYAEEKKDYKIPVTVPDLNEQTTWYYKSAYHIDQRWS 722 Query: 719 IRMASARQRHVDQGQSFNLYVTPDIKATDFLNLHLNAWKGGLKSTYYVRSRALTIEECES 778 I+ +ARQRH+DQ SFN YV IKA + L+LHL AWK GLK+TYYVRS + TI+EC+S Sbjct: 723 IKQNAARQRHIDQAISFNFYVMNTIKAKELLDLHLTAWKSGLKTTYYVRSTSGTIDECDS 782 Query: 779 CAS 781 CAS Sbjct: 783 CAS 785 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 4,531,521,003 Number of extensions: 188374765 Number of successful extensions: 456244 Number of sequences better than 1.0e-05: 2273 Number of HSP's gapped: 446607 Number of HSP's successfully gapped: 2738 Length of query: 781 Length of database: 3,060,696,203 Length adjustment: 144 Effective length of query: 637 Effective length of database: 1,704,070,043 Effective search space: 1085492617391 Effective search space used: 1085492617391 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 135 (56.6 bits)