BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0001.p (257 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DB25.1 B1DB25_9BACL Xylose isomerase domain protein TIM barrel 275 2e-72 Q8R8P6.1 Q8R8P6_THETN Sugar phosphate isomerases/epimerases 184 7e-45 B7R6U3.1 B7R6U3_9THEO AP endonuclease, family 2 184 7e-45 B3K414.1 B3K414_9BACI Xylose isomerase domain protein TIM barrel 184 9e-45 B0K7A8.1 B0K7A8_THEP3 Xylose isomerase domain protein TIM barrel 181 4e-44 >B1DB25.1 B1DB25_9BACL Xylose isomerase domain protein TIM barrel Length = 255 Score = 275 bits (704), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 131/253 (51%), Positives = 177/253 (69%), Gaps = 1/253 (0%) Query: 5 KQQIGIQMYTLRDRAEKDFLGTLRKVAEIGYKSVEFAGYFGVSAAELRKTLDELGLSAPS 64 K +G+Q+YTLRD E+DFLGT+RK A++GYK+VEFAG+F E++ L EL L APS Sbjct: 3 KPVVGLQLYTLRDLTERDFLGTIRKAAQLGYKAVEFAGFFDTPVKEVKALLAELDLQAPS 62 Query: 65 AHVGLDFSSLENMQSA-LSREIEYAREVGLEYLITPSAPLPEQPALDDVLALIPFFEKAS 123 AH+GL+FS ++SA L ++IEYA+E+GL+Y++ P APLPE P +DV L E+A Sbjct: 63 AHIGLNFSEDAAVRSAELDKQIEYAQELGLQYMVAPWAPLPENPEWEDVQKLAGILEEAG 122 Query: 124 ELVRAAGLKYGYHNHDFEFKQVNGQAVIDIWLERIPAEHMVAEFDLGWVHVGGAVPAEYI 183 V AG+ +GYHNH FEF+ VN + V+D LE +PA+++VAEFDLGWVHV G P +Y+ Sbjct: 123 RKVTEAGMTFGYHNHAFEFQLVNNKPVMDHLLELVPAQYLVAEFDLGWVHVAGYKPVDYV 182 Query: 184 SRYAGRVPLVHIKDFGAGHEEADLGKGQVDFDSVFKAADEAGIQHYIVEQEVFXXXXXXX 243 +Y+GRVPLVH KDF GH + ++GKG VD SV A+EAG+Q+ VEQEVF Sbjct: 183 QKYSGRVPLVHFKDFVEGHTDTEIGKGSVDLKSVLPIAEEAGVQYIFVEQEVFPSSSLRS 242 Query: 244 XXXXXDYFRKRGM 256 ++FRK G+ Sbjct: 243 AEISLEFFRKNGL 255 >Q8R8P6.1 Q8R8P6_THETN Sugar phosphate isomerases/epimerases Length = 248 Score = 184 bits (467), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 90/228 (39%), Positives = 140/228 (61%), Gaps = 9/228 (3%) Query: 8 IGIQMYTLRDRAEKDFLGTLRKVAEIGYKSVEFAGYFGVSAAELRKTLDELGLSAPSAHV 67 I +Q+YT+R+ A+KDF GTL KVAE+GY+ VEFAGY G+ A+EL+K LD GL A +HV Sbjct: 4 IALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAGSHV 63 Query: 68 GLDFSSLENMQSALSREIEYAREVGLEYLITPSAPLPEQPALDDVLALIPFFEKASELVR 127 G++ ++ L+ +EY+ E+G Y++ P P + +D + + FF + E + Sbjct: 64 GIEL-----LKKDLNGVLEYSLEIGNRYIVCPGVPYKSK---EDYIEMAKFFNEVGERCK 115 Query: 128 AAGLKYGYHNHDFEFKQVNGQAVIDIWLERIPAEHMVAEFDLGWVHVGGAVPAEYISRYA 187 GL + YHNH EF+ +G+ +DI + E + AE D+ WV G P EY+ +++ Sbjct: 116 EKGLIFCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFS 175 Query: 188 GRVPLVHIKDF-GAGHEEADLGKGQVDFDSVFKAADEAGIQHYIVEQE 234 GR+PL+H+KD G ++G G +DF + K A+E G++ IVEQ+ Sbjct: 176 GRLPLIHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQD 223 >B7R6U3.1 B7R6U3_9THEO AP endonuclease, family 2 Length = 248 Score = 184 bits (467), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 90/228 (39%), Positives = 140/228 (61%), Gaps = 9/228 (3%) Query: 8 IGIQMYTLRDRAEKDFLGTLRKVAEIGYKSVEFAGYFGVSAAELRKTLDELGLSAPSAHV 67 I +Q+YT+R+ A+KDF GTL KVAE+GY+ VEFAGY G+ A+EL+K LD GL A +HV Sbjct: 4 IALQLYTVREEAQKDFTGTLEKVAEMGYEGVEFAGYGGLKASELKKVLDRTGLKAAGSHV 63 Query: 68 GLDFSSLENMQSALSREIEYAREVGLEYLITPSAPLPEQPALDDVLALIPFFEKASELVR 127 G++ ++ L+ +EY+ E+G Y++ P P + +D + + FF + E + Sbjct: 64 GIEL-----LKKDLNGVLEYSLEIGNRYIVCPGVPYKSK---EDYIEMAKFFNEVGERCK 115 Query: 128 AAGLKYGYHNHDFEFKQVNGQAVIDIWLERIPAEHMVAEFDLGWVHVGGAVPAEYISRYA 187 GL + YHNH EF+ +G+ +DI + E + AE D+ WV G P EY+ +++ Sbjct: 116 EKGLIFCYHNHAHEFEIYDGEYGLDILFKNTDKESVKAEIDVYWVKYAGVDPLEYLKKFS 175 Query: 188 GRVPLVHIKDF-GAGHEEADLGKGQVDFDSVFKAADEAGIQHYIVEQE 234 GR+PL+H+KD G ++G G +DF + K A+E G++ IVEQ+ Sbjct: 176 GRLPLIHLKDMDGKDRSNTEIGNGIIDFKKIVKVAEENGVEWLIVEQD 223 >B3K414.1 B3K414_9BACI Xylose isomerase domain protein TIM barrel Length = 257 Score = 184 bits (466), Expect = 9e-45, Method: Compositional matrix adjust. Identities = 99/236 (41%), Positives = 139/236 (58%), Gaps = 10/236 (4%) Query: 5 KQQIGIQMYTLRDRAEKDFLGTLRKVAEIGYKSVEFAGYFGVSAAELRKTLDELGLSAPS 64 + IG+QMYTLRD +DF GTLRKVAE+GY+ VEFAGY + A E++ L ELGL A Sbjct: 3 RMNIGLQMYTLRDETAQDFRGTLRKVAELGYEGVEFAGYGDIPAEEMKTLLQELGLKAIG 62 Query: 65 AHVGLDFSSLENMQSALSREIEYAREVGLEYLITPSAPLPEQPALDDVLALIPFFEKASE 124 +HVGL +++ L +EI+Y + +G +Y++ P ++ +D L F E+ Sbjct: 63 SHVGLHL-----LRADLQKEIDYLKTIGAKYMMCPYVAEEDRKDAEDWKNLFSFLEEVGA 117 Query: 125 LVRAAGLKYGYHNHDFEFK-QVNGQAVIDIWLERIPAEHMVAEFDLGWVHVGGAVPAEYI 183 R GL +GYHNH FEF+ +V+GQ V D E + E D+ WV G P YI Sbjct: 118 EARKQGLIFGYHNHAFEFEAEVDGQFVFDAMYSATTPEAVQVEMDVCWVQFAGQDPLTYI 177 Query: 184 SRYAGRVPLVHIKDFGAGHE----EADLGKGQVDFDSVFKAADEAGIQHYIVEQEV 235 +YAGR+PL+H+KDF E +L +G V+ V +AA +AG + IVEQ+V Sbjct: 178 PKYAGRLPLLHLKDFSKDAEGNMKTLELSQGSVNLPGVIQAASDAGTEWLIVEQDV 233 >B0K7A8.1 B0K7A8_THEP3 Xylose isomerase domain protein TIM barrel Length = 249 Score = 181 bits (460), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 93/228 (40%), Positives = 137/228 (60%), Gaps = 9/228 (3%) Query: 8 IGIQMYTLRDRAEKDFLGTLRKVAEIGYKSVEFAGYFGVSAAELRKTLDELGLSAPSAHV 67 I +Q+YTLR+ +KDF GTL KVAEIGY+ VEFAGY G+ A+ELRKTLD+LGL A +HV Sbjct: 5 IALQLYTLREETQKDFTGTLEKVAEIGYEGVEFAGYGGLKASELRKTLDKLGLKAAGSHV 64 Query: 68 GLDFSSLENMQSALSREIEYAREVGLEYLITPSAPLPEQPALDDVLALIPFFEKASELVR 127 G+D +++ L I+Y E+G +Y++ P E + +D + F K E R Sbjct: 65 GIDL-----LKNNLEEVIDYNLEIGNKYIV---CPWNEYKSREDYIETAKLFNKIGEKCR 116 Query: 128 AAGLKYGYHNHDFEFKQVNGQAVIDIWLERIPAEHMVAEFDLGWVHVGGAVPAEYISRYA 187 GL++ YHNH+ EF+ +G+ +DI + E + AE D WV G P EY+ +++ Sbjct: 117 EKGLEFCYHNHNHEFEIYDGEYGLDILYKNTDKELVKAEIDAYWVTYAGVDPLEYLKKFS 176 Query: 188 GRVPLVHIKDFGAGHEE-ADLGKGQVDFDSVFKAADEAGIQHYIVEQE 234 R+PL+H+KD ++G G ++F V K E G++ IVEQ+ Sbjct: 177 NRLPLIHLKDMDKEDRSFTEIGNGIINFKEVIKITKENGVKWLIVEQD 224 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.138 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,475,655,223 Number of extensions: 62392566 Number of successful extensions: 154182 Number of sequences better than 1.0e-05: 212 Number of HSP's gapped: 153677 Number of HSP's successfully gapped: 212 Length of query: 257 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 124 Effective length of database: 1,807,701,208 Effective search space: 224154949792 Effective search space used: 224154949792 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)