BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0021.0014.p (364 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2B8A1.1 Q2B8A1_9BACI UDP-N-acetylglucosamine 2-epimerase EC=5.1... 490 e-136 Q2RQQ8.1 Q2RQQ8_RHORT UDP-N-acetylglucosamine 2-epimerase EC=5.1... 352 4e-95 C3ED83.1 C3ED83_BACTU UDP-N-acetylglucosamine 2-epimerase 343 1e-92 A6PKC7.1 A6PKC7_9BACT UDP-N-acetylglucosamine 2-epimerase EC=5.1... 342 3e-92 B5JXM6.1 B5JXM6_9GAMM UDP-N-acetylglucosamine 2-epimerase EC=5.1... 340 1e-91 >Q2B8A1.1 Q2B8A1_9BACI UDP-N-acetylglucosamine 2-epimerase EC=5.1.3.14 Length = 372 Score = 490 bits (1261), Expect = e-136, Method: Compositional matrix adjust. Identities = 230/363 (63%), Positives = 287/363 (79%) Query: 1 MKIMTILGTRPEIIRLSVIIPLLDEHAEQHVLVHTGQNFTASLSGIFFAELGLRAPDYVL 60 MK+MTILGTRPEIIRLS+II LD+ +H+LVHTGQNFT +LS +FF E+ +R PD +L Sbjct: 10 MKVMTILGTRPEIIRLSLIINKLDQLCSRHILVHTGQNFTGNLSDVFFREMKVRTPDVIL 69 Query: 61 QDKQAGLGGQLAAMFGSLESILLQEQPDRILLLGDTNSALCAILAERMGIPVVHMEAGNR 120 DKQ LG QL+A+F LE ++L E+PDR+L+LGDTNS L AI+AERMG+PV+HMEAGNR Sbjct: 70 LDKQHSLGEQLSAIFSGLEKLILAERPDRVLVLGDTNSGLGAIIAERMGVPVIHMEAGNR 129 Query: 121 CYDLKVPEEKNRRVIDAVSTINMPYTQQSKRHLLSEGFPSQRIVLTGNPIHEVIKHYNRQ 180 C+DL+VPEEKNR+VIDA+ST N+PYT QS+ +LL EG PS RI+++GNPI+EV++HY + Sbjct: 130 CFDLEVPEEKNRKVIDAISTYNLPYTPQSRENLLREGIPSSRIIVSGNPIYEVLQHYKSE 189 Query: 181 IGASDILDRLNLMAGQYFLVTAHRAENVDDPESLRQIMSGLNLVAEHFGLRLICSIHPRT 240 I S IL+ L L YFL T HRAENVD + L++IM GLNL A+ F LR+ICSIHPRT Sbjct: 190 INQSPILEELKLEPKSYFLATIHRAENVDRADRLKEIMKGLNLTAQKFQLRMICSIHPRT 249 Query: 241 RSKLAEQFKLEMNPLVEFHEPFGFFDFVHLEQYALCAITDSGTVQEECCLMGVPTVTIRR 300 RSKL++ L+M+PLVEFH+PFGFFDFV LE+ A A+TDSGTVQEECCL VP VTIR+ Sbjct: 250 RSKLSQLESLDMHPLVEFHDPFGFFDFVKLEKNAFGALTDSGTVQEECCLFHVPAVTIRK 309 Query: 301 TTERPETVDCGSNVVSGVEQESILRCTRLMTSLSPEWEAPEGYLTPDVSVKVVKFLLGGN 360 TTERPET++CGSN+VSG++ E ILRC +M + W P GY P VS KV+K LLGG Sbjct: 310 TTERPETIECGSNMVSGLKAEDILRCVEVMAASDRNWSFPVGYEQPFVSDKVIKVLLGGM 369 Query: 361 LHV 363 +V Sbjct: 370 KNV 372 >Q2RQQ8.1 Q2RQQ8_RHORT UDP-N-acetylglucosamine 2-epimerase EC=5.1.3.14 Length = 365 Score = 352 bits (902), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 185/368 (50%), Positives = 245/368 (66%), Gaps = 10/368 (2%) Query: 1 MKIMTILGTRPEIIRLSVIIPLLDEHAEQHVLVHTGQNFTASLSGIFFAELGLRAPDYVL 60 MK+MTILGTRPE+IRLS+I+P LD + HV V+TGQN SL F E LR+ D+ L Sbjct: 1 MKVMTILGTRPELIRLSLILPRLDAVCD-HVFVYTGQNAHPSLWRNFLGEFSLRSEDHDL 59 Query: 61 QDKQAGLGGQLAAMFGSLESILLQEQPDRILLLGDTNSALCAILAERMGIPVVHMEAGNR 120 Q LG ++ A+ E ++ E+PDR+L+LGDTNS L A +A+R+GIPV HMEAGNR Sbjct: 60 GASQGTLGERVGAILAGAERVIGLERPDRVLILGDTNSGLSAYVAKRLGIPVFHMEAGNR 119 Query: 121 CYDLKVPEEKNRRVIDAVSTINMPYTQQSKRHLLSEGFPSQRIVLTGNPIHEVIKHYNRQ 180 C+D +VPEE NRRVID S + MPYT+ +R+LL+EG P QRIV+TGNPI EV+ + Sbjct: 120 CHDDRVPEEVNRRVIDHCSDLLMPYTEHGRRNLLAEGIPGQRIVVTGNPIGEVLAAMAER 179 Query: 181 IGASDILDRLNLMAGQYFLVTAHRAENVDDPESLRQIMSGLNLVAEHFGLRLICSIHPRT 240 I A+ L L L G Y L T HR ENVD P+ L +M+G+ V GL + S+HPRT Sbjct: 180 IDAATALGALGLRPGAYLLFTFHRQENVDVPQRLMALMAGVRRVMAVSGLPAVVSVHPRT 239 Query: 241 R-----SKLAEQFKLEMNPLVEFHEPFGFFDFVHLEQYALCAITDSGTVQEECCLMGVPT 295 R S LA+Q + ++ EPFGF DFV LE+ A C ++DSGTVQEE ++GVPT Sbjct: 240 RAHLEASGLADQGRGDLM----LMEPFGFCDFVALEKSARCVLSDSGTVQEEGAILGVPT 295 Query: 296 VTIRRTTERPETVDCGSNVVSGVEQESILRCTRLMTSLSPEWEAPEGYLTPDVSVKVVKF 355 VT+R TERPET++ GSN++ GV+ E++ R RL+T+ P W P Y +V+ VV+ Sbjct: 296 VTLRDVTERPETLETGSNILCGVDPEAMERAFRLVTATPPNWPVPLDYTRMNVADTVVRL 355 Query: 356 LLGGNLHV 363 L+G +L V Sbjct: 356 LIGASLPV 363 >C3ED83.1 C3ED83_BACTU UDP-N-acetylglucosamine 2-epimerase Length = 376 Score = 343 bits (880), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 163/358 (45%), Positives = 243/358 (67%), Gaps = 5/358 (1%) Query: 2 KIMTILGTRPEIIRLSVIIPLLDEHAEQHVLVHTGQNFTASLSGIFFAELGLRAPDYVLQ 61 KI+TI+GTRPEIIRLS +I D + H+LVHTGQN+ +L+ +FF ELGLR PDY L Sbjct: 5 KILTIVGTRPEIIRLSSVIKACDTYF-NHILVHTGQNWDPTLNDVFFEELGLRKPDYFLN 63 Query: 62 DKQAGLGGQLAAMFGSLESILLQEQPDRILLLGDTNSALCAILAERMGIPVVHMEAGNRC 121 LG + + ++ + QP+ +L+LGDTNS LCAI A+R+ IPV HMEAGNRC Sbjct: 64 VVGNHLGETMGNIISKSYELMSEIQPEALLILGDTNSCLCAISAKRLKIPVFHMEAGNRC 123 Query: 122 YDLKVPEEKNRRVIDAVSTINMPYTQQSKRHLLSEGFPSQRIVLTGNPIHEVIKHYNRQI 181 +D VPEE NR+++D VS IN+PYT+ S+R+LLSEG + I++TG+P+HEV+K + ++ Sbjct: 124 FDQNVPEEINRKIVDHVSDINLPYTEHSRRYLLSEGIRKEHIIVTGSPMHEVLKEHKEKV 183 Query: 182 GASDILDRLNLMAGQYFLVTAHRAENVDDPESLRQIMSGLNLVAEHFGLRLICSIHPRTR 241 GAS++L L+L +Y LV+AHR EN+D ++ ++M LN VAE + + ++ S HPR+ Sbjct: 184 GASNVLTELDLKQNEYMLVSAHREENIDHEDNFYRLMESLNAVAETYHMPIVYSTHPRSL 243 Query: 242 SKLAEQFKLEMNPLVEFHEPFGFFDFVHLEQYALCAITDSGTVQEECCLMGVPTVTIRRT 301 ++ E+ + +PLV +PFGFF + HL+Q A C ++DSGT+ EE ++ P V IR + Sbjct: 244 KRIKER-GFKFHPLVRVLKPFGFFAYNHLQQNAFCVLSDSGTLSEESAMLNFPAVLIRTS 302 Query: 302 TERPETVDCGSNVVSGVEQESILRCTRLMTSLSPE---WEAPEGYLTPDVSVKVVKFL 356 TERPE +D GS V+ G+ ++ +L+ L +++ + P Y+ +VS+KVVK + Sbjct: 303 TERPEVLDKGSVVIGGITKDEVLQSIELAKAMANNGDTFNLPVDYVDTNVSIKVVKII 360 >A6PKC7.1 A6PKC7_9BACT UDP-N-acetylglucosamine 2-epimerase EC=5.1.3.14 Length = 382 Score = 342 bits (877), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 166/366 (45%), Positives = 245/366 (66%), Gaps = 12/366 (3%) Query: 1 MKIMTILGTRPEIIRLSVIIPLLDEHAEQHVLVHTGQNFTASLSGIFFAELGLRAPDYVL 60 +K+M+I+GTRPEIIRL+ +I LL+ H + H ++HTGQN+ L+ +FF EL LR PDY L Sbjct: 6 LKVMSIVGTRPEIIRLAAVIKLLEAHVD-HKMIHTGQNYDYELNQVFFEELELRKPDYYL 64 Query: 61 QDKQAGLGGQLAAMFGSLESILLQEQPDRILLLGDTNSALCAILAERMGIPVVHMEAGNR 120 + LG L +E + EQPD +L+LGDTN+A+ I+A+RM IP+ HMEAGNR Sbjct: 65 GVDTSSLGHVLGETLIKVEEVFNAEQPDAVLILGDTNAAIAGIMAKRMKIPIFHMEAGNR 124 Query: 121 CYDLKVPEEKNRRVIDAVSTINMPYTQQSKRHLLSEGFPSQRIVLTGNPIHEVIKHYNRQ 180 +DL VPEE NRR+ID ++ N+ YT+ S+RHLL+EG P + I +TG+P++EV+ Y + Sbjct: 125 SFDLNVPEEINRRIIDHIADFNLVYTENSRRHLLAEGLPHRHIYVTGSPMYEVLHQYMDK 184 Query: 181 IGASDILDRLNLMAGQYFLVTAHRAENVDDPESLRQIMSGLNLVAEHFGLRLICSIHPRT 240 I +S ILD L L +YF+V+ HR ENVD P +LR+I++ LN +AE + + ++ S HPRT Sbjct: 185 IRSSKILDTLKLEKNRYFIVSCHREENVDYPSNLRKILTILNRLAETYDMPVVVSTHPRT 244 Query: 241 RSKLAEQFKLEMNPLVEFHEPFGFFDFVHLEQYALCAITDSGTVQEECCLMGVPTVTIRR 300 R ++ +E++ V+F +PFGFFD+ L+ A CAI+DSGT+ EE ++ P VTIR+ Sbjct: 245 RKRIEALEGVEIDSRVQFLKPFGFFDYNALQLNARCAISDSGTISEESSMLNFPAVTIRQ 304 Query: 301 TTERPETVDCGSNVVSGVEQESILRCTRLMTSLSPEWEAPEG--------YLTPDVSVKV 352 ERPE +D G+ +++G++ E +L RL+ E+E G Y P+ S +V Sbjct: 305 ALERPEAMDAGTIILTGLDPEIVLDSVRLVID---EFEQNGGKYEKICPEYQVPNTSWRV 361 Query: 353 VKFLLG 358 +K +LG Sbjct: 362 LKLILG 367 >B5JXM6.1 B5JXM6_9GAMM UDP-N-acetylglucosamine 2-epimerase EC=5.1.3.14 Length = 381 Score = 340 bits (873), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 163/363 (44%), Positives = 244/363 (67%), Gaps = 6/363 (1%) Query: 1 MKIMTILGTRPEIIRLSVIIPLLDEHAEQHVLVHTGQNFTASLSGIFFAELGLRAPDYVL 60 MK+MTILGTRPEIIRLS ++ LDE E H +VHTGQN+ L+ +FF ELG+R PD+ L Sbjct: 1 MKVMTILGTRPEIIRLSRVMAALDEVVE-HKIVHTGQNYDYELNDVFFEELGVRRPDHFL 59 Query: 61 QDKQAGLGGQLAAMFGSLESILLQEQPDRILLLGDTNSALCAILAERMGIPVVHMEAGNR 120 + LG L + E++LL+E+PD +L+LGDTNSA+ ++A+RM +P HMEAGNR Sbjct: 60 NADTSSLGRCLGDILIKTEAVLLEEKPDAVLVLGDTNSAIATVMAKRMKVPTYHMEAGNR 119 Query: 121 CYDLKVPEEKNRRVIDAVSTINMPYTQQSKRHLLSEGFPSQRIVLTGNPIHEVIKHYNRQ 180 C+D VPEE NR+++D + N+ YT+ ++RHL+SEG + I LTG+P+ EV++H + Sbjct: 120 CFDANVPEEINRKLVDHTADFNLVYTEHARRHLISEGLSHRFIYLTGSPMREVLEHSLDK 179 Query: 181 IGASDILDRLNLMAGQYFLVTAHRAENVDDPESLRQIMSGLNLVAEHFGLRLICSIHPRT 240 I S++L+ L L GQ+F+V+ HR ENVD SL +++ L V E FGL ++ S HPRT Sbjct: 180 IKHSNVLEELGLQTGQFFIVSVHREENVDSKASLEKVVEALQAVHEAFGLPVVVSTHPRT 239 Query: 241 RSKLAEQFKLEMNPLVEFHEPFGFFDFVHLEQYALCAITDSGTVQEECCLMGVPTVTIRR 300 R++L + LE + + F +PFGFFD+ L+ + CAI+DSGT+ EE ++ P VT+RR Sbjct: 240 RNRLEKLGALEQSGDIRFLKPFGFFDYNCLQMASFCAISDSGTISEESSILDFPAVTLRR 299 Query: 301 TTERPETVDCGSNVVSGVEQESILRCTRLMTS-----LSPEWEAPEGYLTPDVSVKVVKF 355 + ERPE +D G+ ++G++ E+++ ++ T+ + E E PE Y + S +VV+ Sbjct: 300 SIERPEALDTGAIALTGLDAEALVDGIKVATASRSVFSNTEPEVPEDYQVRNTSERVVRL 359 Query: 356 LLG 358 + G Sbjct: 360 ITG 362 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.138 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,148,693,330 Number of extensions: 87584405 Number of successful extensions: 212863 Number of sequences better than 1.0e-05: 1247 Number of HSP's gapped: 208488 Number of HSP's successfully gapped: 1248 Length of query: 364 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 227 Effective length of database: 1,770,017,148 Effective search space: 401793892596 Effective search space used: 401793892596 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 132 (55.5 bits)