BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0020.0012.p (526 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1D7N5.1 B1D7N5_9BACL Two component transcriptional regulator, A... 385 e-105 B3K4S1.1 B3K4S1_9BACI Response regulator receiver 362 4e-98 B3KDQ1.1 B3KDQ1_9BACI Response regulator receiver 323 4e-86 A6CLV0.1 A6CLV0_9BACI AraC-type DNA-binding domain-containing pr... 283 2e-74 B1D9L1.1 B1D9L1_9BACL Two component transcriptional regulator, A... 206 7e-51 >B1D7N5.1 B1D7N5_9BACL Two component transcriptional regulator, AraC family Length = 537 Score = 385 bits (988), Expect = e-105, Method: Compositional matrix adjust. Identities = 214/540 (39%), Positives = 320/540 (59%), Gaps = 23/540 (4%) Query: 1 MKVLIVDDEKHVREAIRYFVPWEKYHITDIYEASNGQEAMRIMQEQQPAIVFTDMRMPLM 60 MK+LIVDDE+HVREA++ + WE+ I +IYEA NG A+ ++ QP IV TDMRMP Sbjct: 1 MKILIVDDEQHVREAVKLLIDWEQLGIKEIYEADNGDSAIEMLGNMQPEIVITDMRMPNR 60 Query: 61 DGAELLEWLHSHYPHTKTIVISGYQDFNYVKPAIVYGGTDYLLKPLNSKQLIAAAEHAFK 120 DG ELL W+ +KTIVISGY DF+ V+ ++ YGG DYLLKP++ +QL A + A + Sbjct: 61 DGVELLAWMKEQGRKSKTIVISGYDDFHLVRSSMKYGGQDYLLKPIDPEQLTEALQKAKQ 120 Query: 121 LWLXXXXXXXXXXXXNMQLNVLRPLYWDKMLSDLV--AGQASFQEVRNSLCEELGMPLFV 178 W ++++N ++P+Y DK+ S ++ AG V L EE + Sbjct: 121 SWEQEDQARRLDQQRSIEINQIKPVYRDKLFSTMISEAGAGGQVTVPAVLKEEFRLDR-A 179 Query: 179 AECRVALISLQGADCRLLHRFQGDVGLTSFVLANVCNEVLAPKQNGFAFRSWQGGADIVL 238 EC+V ++S + ++ +F G+ L +F L NVCNE+L PK +GFAFR W +I++ Sbjct: 180 TECQVIILSTGMLEPQISRKFDGNRDLLTFCLINVCNEILKPKNSGFAFRYWNSEHEIII 239 Query: 239 LLWSAVAEAEEEMHRINESIRQTYGVQMDIGLSLPVAFPEGLQRAFRQARQSLGERNLLQ 298 LLW +AE E+ + +I E I ++ + G+ AFP GL ++++ R +L +RNLL+ Sbjct: 240 LLWDRLAEWEDLLGQITEGIVKSIHGRFHYGVGHKQAFPTGLSLSYQEGRAALKQRNLLK 299 Query: 299 REGRIHLFQEQSGTG-SSEKNYAYETQLDKLRIAVLSGDLDKMERVVDEWSDQLAGLPLL 357 IH ++ TG S AYE ++ R+AV SG +E VD + + LP++ Sbjct: 300 DNSYIHCSEQGFKTGIHSLSIAAYE---ERFRLAVWSGKEKDIETAVDSFLENARLLPVI 356 Query: 358 TESQFQQLQAEISEVLRRLR--------------PDGEISFELCYDSEGLFSVENWRSQL 403 T+ Q + + E +L R R P + + D +G S+E R +L Sbjct: 357 TQEQIELWRFEYESMLSRWRQELAAKQGIQAGAEPSSGLPLYVLLDEQGRLSLELCRREL 416 Query: 404 KTLLQRLT--EGNAQTPDSWLVEEIRQYLQQNYARDMTLQHIAERFFISRENVSRKFKQI 461 L G + ++ +I +Y++QNY R++TLQ I+ERF++SRE +SR+FKQ Sbjct: 417 LNGLTAFAALTGAGGNKEHSIMRDIARYMEQNYNREVTLQDISERFYLSREYISRRFKQE 476 Query: 462 TGENLSDYLTGLRVDKAKTLLQNTNLRLSQISELVGYEDEKYFSRVFKKSTGQSPREYRK 521 GEN+ DYL +RV+KAK LLQN NL+++QI+E+VGY+D+KYFS+VFKK GQSP +YRK Sbjct: 477 MGENVFDYLGRIRVEKAKLLLQNPNLKIAQIAEMVGYDDDKYFSKVFKKFEGQSPNQYRK 536 >B3K4S1.1 B3K4S1_9BACI Response regulator receiver Length = 538 Score = 362 bits (930), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 206/539 (38%), Positives = 311/539 (57%), Gaps = 21/539 (3%) Query: 1 MKVLIVDDEKHVREAIRYFVPWEKYHITDIYEASNGQEAMRIMQEQQPAIVFTDMRMPLM 60 M+VLIVDDE+HVREAI WE++ IT+I +A++G+EA+R+++E++P IV TDMRMP Sbjct: 1 MRVLIVDDEQHVREAIGLLADWERHGITEIDQAADGEEAVRLIEEKKPQIVLTDMRMPRK 60 Query: 61 DGAELLEWLHSHYPHTKTIVISGYQDFNYVKPAIVYGGTDYLLKPLNSKQLIAAAEHAFK 120 +G ELL WLH+ P K +VISGY DF YV+ I GG DY+LKP++ L A A + Sbjct: 61 NGLELLTWLHATKPDIKVLVISGYDDFEYVRHTIRSGGIDYILKPVDPDSLNEALAKAVE 120 Query: 121 LWLXXXXXXXXXXXXNMQLNVLRPLYWDKMLSDLVAGQASFQEVRNSLCEELGMPLFVAE 180 W N+++N + P Y D++LSDLV G S + V + L + + +P Sbjct: 121 TWRLEEEKRRHMTNQNIEMNQMTPFYMDRLLSDLVNGYGSRESVVSQLRKRMTLPETGMA 180 Query: 181 CRVALISLQGADCRLLHRFQGDVGLTSFVLANVCNEVLAPKQNGFAFRSWQGGADIVLLL 240 C VA++ D LL +F+ L SF L N+CNE+L K G AFR +I+LL Sbjct: 181 CNVAVLRDDQFDEALLSKFRNRRHLLSFTLINICNELL--KDRGIAFRHIDKPGEIILLC 238 Query: 241 WSAVAEAEEEMHRINESIRQTYGVQMDIGLSLPVAFPEGLQRAFRQARQSLGERNLLQRE 300 W+ + + RIN+ T + G + AFP+ L +A+ A Q+L RNLL Sbjct: 239 WNPRLPFNDLLDRINDGFFSTLRRRSHFGAAEAGAFPQDLPKAYSTAVQALCSRNLLT-- 296 Query: 301 GRIHLFQEQSGTGSSEKNYAYETQLDKLRIAVLSGDLDKMERVVDEWSDQLAGLPLLTES 360 G+ H+ +E++ + + ++ ++A LSG +++E EW ++ L++ Sbjct: 297 GKCHIHRERAVESEGSRTLRLSSYEEEFKLAALSGSKERIEAATAEWLQEVRERDLVSPE 356 Query: 361 QFQQLQAEI---------SEVLRRLRP--DGEISFE----LCYDSEGLFSVENWRSQLKT 405 + +E +EV P D EIS + L Y +G+ + WR Q+ Sbjct: 357 HLMRWNSEWDWIQYHWTENEVKSTQEPVEDAEISQDLPSALPYSEDGMICWDRWREQISG 416 Query: 406 LLQRLTEGNAQ--TPDSWLVEEIRQYLQQNYARDMTLQHIAERFFISRENVSRKFKQITG 463 L + Q + D+ ++ +I QYL+Q+Y +++LQ IA +FF+SRE +SRKFKQ G Sbjct: 417 RLYAASRVLTQIHSKDNHIIHDIAQYLEQHYHDEISLQQIAGKFFLSREYISRKFKQEFG 476 Query: 464 ENLSDYLTGLRVDKAKTLLQNTNLRLSQISELVGYEDEKYFSRVFKKSTGQSPREYRKQ 522 LSD+L +R++KAKTLL N +R++QI+E+VGY+DEKYFS+VFKK G +P EYRK+ Sbjct: 477 VTLSDFLGRIRIEKAKTLLLNPQIRIAQIAEMVGYQDEKYFSKVFKKMEGFTPNEYRKK 535 >B3KDQ1.1 B3KDQ1_9BACI Response regulator receiver Length = 545 Score = 323 bits (827), Expect = 4e-86, Method: Compositional matrix adjust. Identities = 194/543 (35%), Positives = 289/543 (53%), Gaps = 20/543 (3%) Query: 1 MKVLIVDDEKHVREAIRYFVPWEKYHITDIYEASNGQEAMRIMQEQQPAIVFTDMRMPLM 60 MK LIVDDE VR+AIR V WE + ITDI EA+NG EAM ++ +P +V DM MPL Sbjct: 1 MKALIVDDESRVRKAIRLLVQWEAHGITDIEEAANGLEAMELIPAFRPHLVLMDMLMPLK 60 Query: 61 DGAELLEWLHSHYPHTKTIVISGYQDFNYVKPAIVYGGTDYLLKPLNSKQLIAAAEHAFK 120 +G +L+EW+H HYP K IVISG+ DF +V+ I Y GTDY+LKP+ + A A Sbjct: 61 NGVDLMEWIHKHYPDIKFIVISGHDDFEFVRNTIWYSGTDYILKPIEEDVINQAVAKATA 120 Query: 121 LWLXXXXXXXXXXXXNMQLNVLRPLYWDKMLSDLVAGQASFQEVRNSLCEELGMPLFVAE 180 W+ ++Q+N RP+Y +K+LS L+ +++ +V N L +E +P Sbjct: 121 AWMAEEQERLAARQQHVQVNEYRPVYSEKLLSSLIDDRSAHSQVVNRLRDEGIVPAQTNA 180 Query: 181 CRVALISLQGADCRLLHRFQGDVGLTSFVLANVCNEVLAPKQNGFAFRSWQGGADIVLLL 240 R+A++ + +D L RF L F L N+CNE L + G AFR + +VLLL Sbjct: 181 IRLAVMQIDKSDHVLYSRFGHHQDLLMFALLNICNEFLQKDRIGIAFRPFGSPHQLVLLL 240 Query: 241 WSAVAEAEEEMHRINESIRQTYGVQMDIGLSLPVAFPEGLQRAFRQARQSLGERNLLQRE 300 W +A + IN + +T QM G+S +P + + Q +L R+L Sbjct: 241 WEQLATVPTLLQEINSGMFRTLSRQMHFGISPEGKYPVDVPELYAQCSNALRSRDLTVLN 300 Query: 301 GRIHLFQEQSGTG-SSEKNYAYETQLDKLRIAVLSGDLDKMERVVDEWSDQLAGLPLLTE 359 IH ++ +G + + D ++AVLSG + VD + + +LT Sbjct: 301 HFIHDAEQLRRSGMDHHRGVQFSGFEDTWKLAVLSGQPAPIGEAVDSFLAAIRKSGVLTP 360 Query: 360 SQFQQLQAEI---------------SEVLRRLRPDGEISFELCYDSEGLFSVENWR---S 401 ++ EI SE L +L + + E + + S+ W+ Sbjct: 361 ELLERWDREIDRFANHVIHETANPSSEALLKLYKEESATIERPSPDKYVCSLAEWQQYWD 420 Query: 402 QLKTLLQRLTEGNAQTPDSWLVEEIRQYLQQNYARDMTLQHIAERFFISRENVSRKFKQI 461 QL +LL + QT L+ +I +++QNY D++L IA RF +SRE +SRKFKQ Sbjct: 421 QLMSLLASALQSQKQTGQD-LIYDITAFIEQNYQNDVSLYDIANRFHVSREYISRKFKQK 479 Query: 462 TGENLSDYLTGLRVDKAKTLLQNTNLRLSQISELVGYEDEKYFSRVFKKSTGQSPREYRK 521 G N+ ++L +R+ KAK LLQN L+++ ISE+VG+++EKYFS VFKK G SP+E+RK Sbjct: 480 HGINIPEHLNRIRISKAKILLQNPGLKMAAISEMVGFKNEKYFSLVFKKQEGISPKEFRK 539 Query: 522 QGE 524 E Sbjct: 540 LHE 542 >A6CLV0.1 A6CLV0_9BACI AraC-type DNA-binding domain-containing protein Length = 525 Score = 283 bits (725), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 179/535 (33%), Positives = 291/535 (54%), Gaps = 30/535 (5%) Query: 1 MKVLIVDDEKHVREAIRYFVPWEKYHITDIYEASNGQEAMRIMQEQQPAIVFTDMRMPLM 60 MK +I+DDEKHVRE + WEK+ I I EA +G++A+ +++E +P I+FTDMRMP Sbjct: 1 MKAIIIDDEKHVREGLILLAEWEKFGIHTILEAEDGEQAIELIKEHRPEIIFTDMRMPRK 60 Query: 61 DGAELLEWLHSHYPHTKTIVISGYQDFNYVKPAIVYGGTDYLLKPLNSKQLIAAAEHAFK 120 DG LL+WLHS H+KTIV+SGY D+ Y++ A+ Y DY+LKP+ + L A E A Sbjct: 61 DGISLLKWLHSSELHSKTIVVSGYDDYEYMRNALYYKSFDYILKPIEPEVLNEALEKAVS 120 Query: 121 LWLXXXXXXXXXXXXNMQLNVLRPLYWDKMLSDLVAGQASFQEVRNSLCEELGMPLFVAE 180 W + LN ++PLYWD+M S L + N + E G+ L Sbjct: 121 EWKDQARSRKSQVEDSQVLNEVKPLYWDRMFSKLCLTGGLSEAAENRIRNEYGLSLTDKG 180 Query: 181 CRVALISLQGADCRLLHRFQGDVGLTSFVLANVCNEVLAPKQNGFAFRSWQGGADIVLLL 240 ++ALI ++ ++ FQ + L F L+N+ NE+L G FR+ ++V+L+ Sbjct: 181 VKIALIPIRPF---VVKAFQFEDELAFFTLSNIGNELLRRSNEGVCFRNINNDEELVILI 237 Query: 241 WSAVAEAEEEMHRINESIRQTYGVQMDIGLSLPVAFPEGLQRAFRQARQSLGERNLLQRE 300 W+A A + I+ +I Q V+ + L A +G A+ + Q L + +LL + Sbjct: 238 WNA-DNAPLLIQDIHTAIYQYSKVRPIMALGKHSADVKG---AYDSSHQVLRKHDLLSAK 293 Query: 301 GRIHLFQEQSGTGSSEKNYAYETQLD---KLRIAVLSGDLDKMERVVDEWSDQLAGLPLL 357 + T N LD L+ A+ SG +++++ ++ + L Sbjct: 294 RVV--------TEEDILNTPLLHLLDYSNDLKWALRSGSMEQIDTQINSLFNLLEKDFTF 345 Query: 358 TESQF----QQLQAEISEVLRRLRPDGEISF---ELCYDSEGLFSVENWR----SQLKTL 406 + Q +Q + + L+ + E++F E + +G FS+ ++ + K L Sbjct: 346 SLDQIATWDRQFELLKNNWLKEYEINNEVTFVKREDYWKEDGTFSLPKFKKEKADEFKEL 405 Query: 407 LQRLTEGNAQTPDSWLVEEIRQYLQQNYARDMTLQHIAERFFISRENVSRKFKQITGENL 466 ++ L++ Q + + + I +YLQ+NY D+ LQ IA+RF++SRE +SRKFKQ + Sbjct: 406 VKILSDAKYQKEKNSM-QRIEEYLQKNYQEDINLQEIADRFYLSREYISRKFKQDYDATI 464 Query: 467 SDYLTGLRVDKAKTLLQNTNLRLSQISELVGYEDEKYFSRVFKKSTGQSPREYRK 521 +DYLT +R++KAK LL+N L++ +++ VGY++EKYFS+VFKK G +P EYR+ Sbjct: 465 TDYLTSIRMEKAKNLLKNPYLKIYEVAYGVGYQNEKYFSKVFKKHEGVTPNEYRQ 519 >B1D9L1.1 B1D9L1_9BACL Two component transcriptional regulator, AraC family Length = 544 Score = 206 bits (523), Expect = 7e-51, Method: Compositional matrix adjust. Identities = 158/554 (28%), Positives = 265/554 (47%), Gaps = 53/554 (9%) Query: 2 KVLIVDDEKHVREAIRYFVPWEKYHITDIYEASNGQEAMRIMQEQQPAIVFTDMRMPLMD 61 KVLI+DDE+ +REAIR W+ + ++ EA++G+ + ++ +V DM+MP M Sbjct: 3 KVLIIDDEEPLREAIRILGDWKGLGVAEVLEATDGKMGLEMIANHSVDLVMVDMKMPGMS 62 Query: 62 GAELLEWLHSHYPHTKTIVISGYQDFNYVKPAIVYGGTDYLLKPLNSKQLIAAAEHAFKL 121 GAELL+ L YP IVISGY DF Y + AI DYLLKP+N L AA A L Sbjct: 63 GAELLQVLERDYPDMPAIVISGYNDFEYTRQAIRSKVVDYLLKPINRPDLNAALRKAVDL 122 Query: 122 WLXXXXXXXXXXXXNMQLNVLRPLYWDKMLSDLVAGQASFQEVRNSLCEELGMPLFVA-- 179 N+ LN+ P +KM ++ SF+ N E +PL A Sbjct: 123 LEARRVRESEFINRNITLNMSLPKLKEKMYLSII--DRSFRSQTN----EAFLPLIGADD 176 Query: 180 -ECRVALISLQGADCRLLH--RFQGDVGLTSFVLANVCNEVLAPKQNGFAFRSWQGGADI 236 + R A + L+ + + RF DV L F + N+ NE+ F+F S + ++ Sbjct: 177 PDNRFAAVVLRMLNMEKVRKARFHSDVDLLHFAVGNMLNEIAGEYFQAFSFASPKMDREL 236 Query: 237 VLLLWSAVAEAEE----EMHRINE---SIRQTYGVQMDIGLSLPVAFPEGLQRAFRQARQ 289 +++L A E+ +H++N+ +++ G+ G+ P + ++ A+ Sbjct: 237 IVILTMKGAYQEDIAYRSLHQMNKALAALQDLLGIVAAAGIGTPCESIMEIASSYETAKA 296 Query: 290 SLGERNLLQREGRIHLFQEQSGTGSSEKNYAYETQLDKLRIAVLSGDLDKMERVVDEWSD 349 ++ +LL+ +G F + S+ + Y ++ R A+ SG+ + ++ E Sbjct: 297 AINGIDLLKLKG---YFVANAVAKSANEGYPVTGRMQMFRAALESGNTAGAKSILSEELR 353 Query: 350 QLAGLPLLTESQFQQLQAEISEVLRRLRPDGEISFELCYDSEGLFSVE-----------N 398 + G L T Q ++ +IS EL E L +E + Sbjct: 354 KWGGADLFTLGDADQSLGRFIILM------NDISLELGVPREKLPLMEEHPVRFMGLSDD 407 Query: 399 WRS--QLKTLLQ----------RLTEGNAQTPDSWLVEEIRQYLQQNYARDMTLQHIAER 446 + S Q LL+ RLT+ +A P + + +I+ Y+ Y D+ + A++ Sbjct: 408 YASYEQFSKLLEDALHFYLEQLRLTQ-SANRP--FEIGDIKAYIDNRYYEDIKISMFADK 464 Query: 447 FFISRENVSRKFKQITGENLSDYLTGLRVDKAKTLLQNTNLRLSQISELVGYEDEKYFSR 506 +F+SRE + + FKQ G + +Y+ +R+DKAK LL + +L++ ISE++GY+D+ YFS+ Sbjct: 465 YFLSREYIMKLFKQQFGCGIHEYVQRIRMDKAKELLDDPSLKIQDISEMLGYKDKNYFSK 524 Query: 507 VFKKSTGQSPREYR 520 F+ SP EYR Sbjct: 525 AFRNYFSISPTEYR 538 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,991,707,726 Number of extensions: 118671191 Number of successful extensions: 425935 Number of sequences better than 1.0e-05: 10495 Number of HSP's gapped: 438444 Number of HSP's successfully gapped: 11147 Length of query: 526 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 385 Effective length of database: 1,732,333,088 Effective search space: 666948238880 Effective search space used: 666948238880 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)