BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0008.p (508 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0YJD9.1 B0YJD9_PAEPO Lysyl-tRNA synthetase EC=6.1.1.6 893 0.0 B1DIC7.1 B1DIC7_9BACL Lysyl-tRNA synthetase EC=6.1.1.6 838 0.0 C0ZIE1.1 C0ZIE1_BREBN Lysyl-tRNA synthetase EC=6.1.1.6 771 0.0 B7GFK7.1 B7GFK7_ANOFW Lysyl-tRNA synthetase EC=6.1.1.6 766 0.0 C5D3A2.1 C5D3A2_9BACI Lysyl-tRNA synthetase EC=6.1.1.6 762 0.0 >B0YJD9.1 B0YJD9_PAEPO Lysyl-tRNA synthetase EC=6.1.1.6 Length = 506 Score = 893 bits (2307), Expect = 0.0, Method: Compositional matrix adjust. Identities = 422/489 (86%), Positives = 462/489 (94%) Query: 18 LSELLTIRRGKLDELRALGIDPFGKKYERTAGAGDIMDKYDGQTKEELDELNLEVSIAGR 77 LSELL IRR KLDELR+LGIDPFG+KY RTA AG ++ KYD TKEEL+E N+EVSIAGR Sbjct: 17 LSELLQIRRAKLDELRSLGIDPFGRKYIRTAEAGVLLSKYDSLTKEELEEKNIEVSIAGR 76 Query: 78 IMAKRVMGKASFAHIQDLSGKIQIYVRQDSISEAQYAAFTVLDLGDIIGVRGTVFKTRTG 137 IMAKRVMGKASFAHIQDLSG+IQIYVRQD++ E++Y AF +LDLGDI+GV+G +FKT+TG Sbjct: 77 IMAKRVMGKASFAHIQDLSGRIQIYVRQDTVPESKYKAFGILDLGDIVGVKGVLFKTKTG 136 Query: 138 ETSIKVHNLEVLSKSLLPLPEKYHGLKDVELRYRQRYVDLIINPEVQQTFITRSRIIQSM 197 ET+IKV ++EVLSKSL PLPEKYHGLKDVELRYRQRYVDL++NPEVQ+TFITRSRIIQSM Sbjct: 137 ETTIKVLDIEVLSKSLYPLPEKYHGLKDVELRYRQRYVDLVMNPEVQKTFITRSRIIQSM 196 Query: 198 RRYLDSLGYLEVETPTLHAIAGGAAARPFITHHNTLDMQLYMRIAIELHLKRLIVGGLEK 257 RRYLDSLGYLEVETPTLH+IAGGAAA+PF+THHN LDMQLYMRIAIELHLKRLIVGG+EK Sbjct: 197 RRYLDSLGYLEVETPTLHSIAGGAAAKPFVTHHNALDMQLYMRIAIELHLKRLIVGGMEK 256 Query: 258 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMHLTESMIAHIAQEVLGTQKINYQ 317 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIM LTE+M+AHIAQEVLGTQ I YQ Sbjct: 257 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMQLTENMVAHIAQEVLGTQHIQYQ 316 Query: 318 GQEVDLTPQWRRVSMVDAVKEVTGVDFGVHMTDEEAQRLAKEHRVPVEKHMTFGHILNAF 377 GQEVDLTPQWRRVSMVDAVKEVTGVDF V M++EEA RLAKEH+V VE HMTFGHILNAF Sbjct: 317 GQEVDLTPQWRRVSMVDAVKEVTGVDFSVQMSNEEAHRLAKEHKVSVEPHMTFGHILNAF 376 Query: 378 FEQFVEETLIQPTFVTGHPVEISPLAKKNDQDPRFTDRFELFIVAREHANAFSELNDPID 437 FEQFVEETLIQPTF+TGHPVEISPLAKKN+QDPRFTDRFELF+VAREHANAF+ELNDPID Sbjct: 377 FEQFVEETLIQPTFITGHPVEISPLAKKNEQDPRFTDRFELFVVAREHANAFTELNDPID 436 Query: 438 QRQRFEAQIQEKEKGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLIMLLTDAASIRDV 497 QRQRFEAQ+ E+E GNDEAHEMDDDFIRALEYGMPPTGGLGIG+DRL+MLLTDA SIRDV Sbjct: 437 QRQRFEAQLLEREHGNDEAHEMDDDFIRALEYGMPPTGGLGIGIDRLVMLLTDAPSIRDV 496 Query: 498 LLFPHMRNR 506 LLFPHMRN+ Sbjct: 497 LLFPHMRNQ 505 >B1DIC7.1 B1DIC7_9BACL Lysyl-tRNA synthetase EC=6.1.1.6 Length = 505 Score = 838 bits (2165), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/489 (83%), Positives = 444/489 (90%) Query: 18 LSELLTIRRGKLDELRALGIDPFGKKYERTAGAGDIMDKYDGQTKEELDELNLEVSIAGR 77 LSELL IRR KLDELRALG+DPFG K+ERT A DI+ Y+ +KEEL+E ++VS+AGR Sbjct: 14 LSELLQIRRDKLDELRALGVDPFGVKFERTHNAKDIVSAYEELSKEELEEKAIKVSVAGR 73 Query: 78 IMAKRVMGKASFAHIQDLSGKIQIYVRQDSISEAQYAAFTVLDLGDIIGVRGTVFKTRTG 137 IM KR MGKASFAHIQDLSGKIQIYVR+D++ +YAAF +LD+GDI+G+ G VFKT TG Sbjct: 74 IMQKRGMGKASFAHIQDLSGKIQIYVRKDTVEANKYAAFEMLDIGDIVGITGVVFKTNTG 133 Query: 138 ETSIKVHNLEVLSKSLLPLPEKYHGLKDVELRYRQRYVDLIINPEVQQTFITRSRIIQSM 197 E S+K + +EVL+KSLLPLP+KYHGLKDVELRYRQRYVDLI+NP+VQQTFITRSRIIQSM Sbjct: 134 EVSVKAYEVEVLTKSLLPLPDKYHGLKDVELRYRQRYVDLIVNPDVQQTFITRSRIIQSM 193 Query: 198 RRYLDSLGYLEVETPTLHAIAGGAAARPFITHHNTLDMQLYMRIAIELHLKRLIVGGLEK 257 RRYLDS GYLEVETPTLH+IAGGAAARPFITHHN LDMQLYMRIAIELHLKRLIVGGLEK Sbjct: 194 RRYLDSKGYLEVETPTLHSIAGGAAARPFITHHNALDMQLYMRIAIELHLKRLIVGGLEK 253 Query: 258 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMHLTESMIAHIAQEVLGTQKINYQ 317 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIM LTE++IAHIAQEVLGT KI+YQ Sbjct: 254 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMALTENLIAHIAQEVLGTMKISYQ 313 Query: 318 GQEVDLTPQWRRVSMVDAVKEVTGVDFGVHMTDEEAQRLAKEHRVPVEKHMTFGHILNAF 377 GQE+DLTPQWRRVSMVD VKEVTGVDF V M+DEEA LAK H+VPVE HMTFGHILNAF Sbjct: 314 GQEIDLTPQWRRVSMVDLVKEVTGVDFSVEMSDEEAHALAKVHKVPVEPHMTFGHILNAF 373 Query: 378 FEQFVEETLIQPTFVTGHPVEISPLAKKNDQDPRFTDRFELFIVAREHANAFSELNDPID 437 FE E TLIQPTFVTGHPV ISPLAKKN DPRFTDRFELF+VAREHANAF+ELNDPID Sbjct: 374 FETHCEHTLIQPTFVTGHPVAISPLAKKNPVDPRFTDRFELFVVAREHANAFTELNDPID 433 Query: 438 QRQRFEAQIQEKEKGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLIMLLTDAASIRDV 497 QRQRFEAQ+ EKE+GNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRL+MLLTDA SIRDV Sbjct: 434 QRQRFEAQLVEKEQGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLVMLLTDAPSIRDV 493 Query: 498 LLFPHMRNR 506 LLFPHMR R Sbjct: 494 LLFPHMRER 502 >C0ZIE1.1 C0ZIE1_BREBN Lysyl-tRNA synthetase EC=6.1.1.6 Length = 506 Score = 771 bits (1991), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/489 (75%), Positives = 418/489 (85%) Query: 18 LSELLTIRRGKLDELRALGIDPFGKKYERTAGAGDIMDKYDGQTKEELDELNLEVSIAGR 77 L ELL +R K+++LR G DPFGKK+E+T A DI + ++KEEL+ V+IAGR Sbjct: 17 LHELLQVRHDKMNQLREWGFDPFGKKFEQTHHAADITKAFSEKSKEELEAEENVVTIAGR 76 Query: 78 IMAKRVMGKASFAHIQDLSGKIQIYVRQDSISEAQYAAFTVLDLGDIIGVRGTVFKTRTG 137 +MAKR MGKASFA + D SG+IQIYVRQD++ E F + D+GD+IGV G VFKT+TG Sbjct: 77 LMAKRGMGKASFAQLLDRSGQIQIYVRQDTVGEELSKVFDLADIGDMIGVTGVVFKTKTG 136 Query: 138 ETSIKVHNLEVLSKSLLPLPEKYHGLKDVELRYRQRYVDLIINPEVQQTFITRSRIIQSM 197 E S+K L L+KSL PLPEKYHGLKD+E RYR+RYVDLI+NPEV+ TFITRSRI+ SM Sbjct: 137 ELSVKAKELSYLTKSLRPLPEKYHGLKDIETRYRKRYVDLIVNPEVRDTFITRSRILTSM 196 Query: 198 RRYLDSLGYLEVETPTLHAIAGGAAARPFITHHNTLDMQLYMRIAIELHLKRLIVGGLEK 257 RRYLD+LGYLEVETPTLHAIAGGA+ARPFITHHN LDMQLYMRIAIELHLKRLIVGGLEK Sbjct: 197 RRYLDNLGYLEVETPTLHAIAGGASARPFITHHNALDMQLYMRIAIELHLKRLIVGGLEK 256 Query: 258 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMHLTESMIAHIAQEVLGTQKINYQ 317 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADY+DIM LTE M+AHIAQEVLGT KI YQ Sbjct: 257 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYQDIMSLTEEMVAHIAQEVLGTMKIQYQ 316 Query: 318 GQEVDLTPQWRRVSMVDAVKEVTGVDFGVHMTDEEAQRLAKEHRVPVEKHMTFGHILNAF 377 G E+DLTP+WRRV MVD +KE GVDF M+D+EA+ LAKEH V VE H TFGH++N F Sbjct: 317 GNEIDLTPKWRRVHMVDLIKENLGVDFWKEMSDDEARALAKEHGVSVEPHHTFGHVVNEF 376 Query: 378 FEQFVEETLIQPTFVTGHPVEISPLAKKNDQDPRFTDRFELFIVAREHANAFSELNDPID 437 FEQ +E TLIQPTFV GHPV ISPLAKKNDQDPRFTDRFELFIVAREHANAF+ELNDPID Sbjct: 377 FEQKLEHTLIQPTFVYGHPVAISPLAKKNDQDPRFTDRFELFIVAREHANAFTELNDPID 436 Query: 438 QRQRFEAQIQEKEKGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLIMLLTDAASIRDV 497 QR+RFEAQ+ EKE GNDEAH+MDDDFI ALEYGMPPTGGLGIG+DRL+MLLT++ SIRDV Sbjct: 437 QRERFEAQLLEKEAGNDEAHDMDDDFIEALEYGMPPTGGLGIGIDRLVMLLTNSPSIRDV 496 Query: 498 LLFPHMRNR 506 LLFPHMRNR Sbjct: 497 LLFPHMRNR 505 >B7GFK7.1 B7GFK7_ANOFW Lysyl-tRNA synthetase EC=6.1.1.6 Length = 494 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 368/489 (75%), Positives = 421/489 (86%) Query: 18 LSELLTIRRGKLDELRALGIDPFGKKYERTAGAGDIMDKYDGQTKEELDELNLEVSIAGR 77 L++ L +RR KL +LR GIDPFGK++ERT A ++ Y +KEEL+E + VSIAGR Sbjct: 6 LNDQLLVRREKLHKLREKGIDPFGKRFERTHQAEELFTLYGHLSKEELEEKQIHVSIAGR 65 Query: 78 IMAKRVMGKASFAHIQDLSGKIQIYVRQDSISEAQYAAFTVLDLGDIIGVRGTVFKTRTG 137 IM KR GKA FAHIQDL+G+IQIYVR+D + E QY F DLGDI+GV+GTVFKT+ G Sbjct: 66 IMTKRGKGKAGFAHIQDLTGQIQIYVRKDDVGEEQYEIFDTSDLGDIVGVQGTVFKTKVG 125 Query: 138 ETSIKVHNLEVLSKSLLPLPEKYHGLKDVELRYRQRYVDLIINPEVQQTFITRSRIIQSM 197 E SIKVH+ E+L+KSL PLPEKYHGLKD+E RYRQRY+DLI+NPE ++TFITRS IIQSM Sbjct: 126 ELSIKVHSYEMLTKSLRPLPEKYHGLKDIEQRYRQRYLDLIMNPESKKTFITRSLIIQSM 185 Query: 198 RRYLDSLGYLEVETPTLHAIAGGAAARPFITHHNTLDMQLYMRIAIELHLKRLIVGGLEK 257 RRYLD GYLEVETP +H+IAGGAAARPFITHHN LDM LYMRIAIELHLKRLIVGGLEK Sbjct: 186 RRYLDQKGYLEVETPMMHSIAGGAAARPFITHHNALDMTLYMRIAIELHLKRLIVGGLEK 245 Query: 258 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMHLTESMIAHIAQEVLGTQKINYQ 317 VYEIGRV+RNEGISTRHNPEFTM+ELYEAYADY DIM LTE MIAHIAQEVLGT KI Y Sbjct: 246 VYEIGRVFRNEGISTRHNPEFTMLELYEAYADYTDIMRLTEDMIAHIAQEVLGTTKIQYG 305 Query: 318 GQEVDLTPQWRRVSMVDAVKEVTGVDFGVHMTDEEAQRLAKEHRVPVEKHMTFGHILNAF 377 EVDLTP W+R+ MVDA+K+ GVDF HM+DEEA++LAKEH V V HMTFGHI+N F Sbjct: 306 EHEVDLTPSWKRLHMVDAIKDYVGVDFWKHMSDEEARQLAKEHGVEVAPHMTFGHIVNEF 365 Query: 378 FEQFVEETLIQPTFVTGHPVEISPLAKKNDQDPRFTDRFELFIVAREHANAFSELNDPID 437 FEQ VE+ LIQPTF+ GHPVEISPLAKKN +DPRFTDRFELFIVAREHANAF+ELNDPID Sbjct: 366 FEQKVEQHLIQPTFIYGHPVEISPLAKKNPEDPRFTDRFELFIVAREHANAFTELNDPID 425 Query: 438 QRQRFEAQIQEKEKGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLIMLLTDAASIRDV 497 QR+RFEAQ++EKE+GNDEAHEMD+DFI ALEYGMPPTGGLGIG+DRL+MLLT++ SIRDV Sbjct: 426 QRERFEAQLREKEQGNDEAHEMDEDFIEALEYGMPPTGGLGIGIDRLVMLLTNSPSIRDV 485 Query: 498 LLFPHMRNR 506 LLFP MR++ Sbjct: 486 LLFPQMRHK 494 >C5D3A2.1 C5D3A2_9BACI Lysyl-tRNA synthetase EC=6.1.1.6 Length = 494 Score = 762 bits (1968), Expect = 0.0, Method: Compositional matrix adjust. Identities = 362/489 (74%), Positives = 422/489 (86%) Query: 18 LSELLTIRRGKLDELRALGIDPFGKKYERTAGAGDIMDKYDGQTKEELDELNLEVSIAGR 77 L++ L +RR KL++LR +GIDPFGK++ERT A ++ D Y +KEEL+E ++V++AGR Sbjct: 6 LNDQLLVRREKLNKLREMGIDPFGKRFERTHKAKELFDLYGDLSKEELEEKQIKVAVAGR 65 Query: 78 IMAKRVMGKASFAHIQDLSGKIQIYVRQDSISEAQYAAFTVLDLGDIIGVRGTVFKTRTG 137 IM KR GKA FAHIQD++G+IQIYVR+D++ E QY F DLGDIIGV GTVFKT+ G Sbjct: 66 IMTKRGKGKAGFAHIQDVTGQIQIYVREDTVGEEQYELFKTSDLGDIIGVYGTVFKTKVG 125 Query: 138 ETSIKVHNLEVLSKSLLPLPEKYHGLKDVELRYRQRYVDLIINPEVQQTFITRSRIIQSM 197 E SIKV + E L+K+L PLPEKYHGLKD+E RYRQRY+DLI+NPE + TFITRSRIIQ+M Sbjct: 126 ELSIKVSSYEFLTKALRPLPEKYHGLKDIEQRYRQRYLDLIMNPESKNTFITRSRIIQAM 185 Query: 198 RRYLDSLGYLEVETPTLHAIAGGAAARPFITHHNTLDMQLYMRIAIELHLKRLIVGGLEK 257 RRYLDS GYLEVETP +H+IAGGAAARPFITHHN LDM LYMRIAIELHLKRLIVGGLEK Sbjct: 186 RRYLDSHGYLEVETPMMHSIAGGAAARPFITHHNALDMPLYMRIAIELHLKRLIVGGLEK 245 Query: 258 VYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMHLTESMIAHIAQEVLGTQKINYQ 317 VYEIGRV+RNEGISTRHNPEFTM+ELYEAYAD++DIM LTE++IAHIAQEVLGT KI Y Sbjct: 246 VYEIGRVFRNEGISTRHNPEFTMLELYEAYADFRDIMKLTENLIAHIAQEVLGTTKIQYG 305 Query: 318 GQEVDLTPQWRRVSMVDAVKEVTGVDFGVHMTDEEAQRLAKEHRVPVEKHMTFGHILNAF 377 VDLTP+W+R+ MVDA+KE GVDF M+DEEA+ LAKEH V + HMTFGHI+N F Sbjct: 306 EHTVDLTPEWKRLHMVDAIKEYVGVDFWKQMSDEEARELAKEHGVEIAPHMTFGHIVNEF 365 Query: 378 FEQFVEETLIQPTFVTGHPVEISPLAKKNDQDPRFTDRFELFIVAREHANAFSELNDPID 437 FEQ VE+ LIQPTF+ GHPVEISPLAKKN DPRFTDRFELFIV REHANAF+ELNDPID Sbjct: 366 FEQKVEDKLIQPTFIYGHPVEISPLAKKNPDDPRFTDRFELFIVGREHANAFTELNDPID 425 Query: 438 QRQRFEAQIQEKEKGNDEAHEMDDDFIRALEYGMPPTGGLGIGVDRLIMLLTDAASIRDV 497 QR+RFEAQ++E+E+GNDEAHEMD+DFI ALEYGMPPTGGLGIGVDRL+MLLT++ SIRDV Sbjct: 426 QRERFEAQLKEREQGNDEAHEMDEDFIEALEYGMPPTGGLGIGVDRLVMLLTNSPSIRDV 485 Query: 498 LLFPHMRNR 506 LLFP MRN+ Sbjct: 486 LLFPQMRNK 494 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,867,295,881 Number of extensions: 121638894 Number of successful extensions: 331467 Number of sequences better than 1.0e-05: 4824 Number of HSP's gapped: 323911 Number of HSP's successfully gapped: 5064 Length of query: 508 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 368 Effective length of database: 1,741,754,103 Effective search space: 640965509904 Effective search space used: 640965509904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)