BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0016.0002.p (285 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B0YJD3.1 B0YJD3_PAEPO Dihydropteroate synthase 420 e-116 B3K911.1 B3K911_9BACI Dihydropteroate synthase EC=2.5.1.15 412 e-113 B1DID3.1 B1DID3_9BACL Dihydropteroate synthase EC=2.5.1.15 339 1e-91 A7GJY4.1 A7GJY4_BACCN Dihydropteroate synthase EC=2.5.1.15 334 6e-90 C2Q612.1 C2Q612_BACCE Dihydropteroate synthase 330 1e-88 >B0YJD3.1 B0YJD3_PAEPO Dihydropteroate synthase Length = 276 Score = 420 bits (1080), Expect = e-116, Method: Compositional matrix adjust. Identities = 201/268 (75%), Positives = 233/268 (86%) Query: 12 LGAAELALGERTLIMGILNVTPDSFSDGGLWAEPEKAVEHALQMAEEGADIIDIGGESTR 71 +G AEL LG T IMGILNVTPDSFSDGGL PE AV HAL++ E+GADIIDIGGESTR Sbjct: 1 MGDAELTLGHSTQIMGILNVTPDSFSDGGLHYSPEIAVLHALKLVEDGADIIDIGGESTR 60 Query: 72 PGHQPVGLEEELARVLPVIESIHRAAPQLVLSIDTYKAEVARRAIQAGAHIINDVWGAKA 131 PGH PVG+EEELARV+PV+E+IHR AP + LS+DTYKAEVAR+A++AGAHIINDVWG KA Sbjct: 61 PGHDPVGVEEELARVIPVVEAIHRIAPHIPLSVDTYKAEVARKALEAGAHIINDVWGFKA 120 Query: 132 DPDMAPVAAEAGCPVILMHNRRERNYRELVSDMCADLGDSVKQALAAGVKRENIILDPGI 191 DPDMA VA+E CPVILMHNR +RNY +LVSDM +DL +S++ AL AGV+ E IILDPGI Sbjct: 121 DPDMARVASEFDCPVILMHNRHDRNYSDLVSDMLSDLKESIRLALDAGVREEQIILDPGI 180 Query: 192 GFAKDYAENLQTMMNLDRLTELGYPLLLATSRKKFIRTVLDLPPDDVVEGTAATVAFGIA 251 GFAKDY EN+ M +LD L++LG+PLLLATSRK+FIRT LDLP +DVVEGTAATVAFGIA Sbjct: 181 GFAKDYDENIHAMTSLDTLSQLGFPLLLATSRKRFIRTALDLPVNDVVEGTAATVAFGIA 240 Query: 252 QGCQIVRVHDVARIKRTVQMCDAMLYAA 279 QGCQIVRVHDVA+IKRTV+MCDAM+Y + Sbjct: 241 QGCQIVRVHDVAQIKRTVRMCDAMVYGS 268 >B3K911.1 B3K911_9BACI Dihydropteroate synthase EC=2.5.1.15 Length = 286 Score = 412 bits (1058), Expect = e-113, Method: Compositional matrix adjust. Identities = 201/283 (71%), Positives = 233/283 (82%), Gaps = 1/283 (0%) Query: 1 MRPLIYKRNYRLGA-AELALGERTLIMGILNVTPDSFSDGGLWAEPEKAVEHALQMAEEG 59 M+ IY+R YRLG AEL LG+ TLIMGILNVTPDSFSDGG + + E+AVEHALQ+ EEG Sbjct: 1 MKTTIYEREYRLGKDAELKLGQSTLIMGILNVTPDSFSDGGRYNDTERAVEHALQLIEEG 60 Query: 60 ADIIDIGGESTRPGHQPVGLEEELARVLPVIESIHRAAPQLVLSIDTYKAEVARRAIQAG 119 ADIIDIGGESTRPGH+PVG EELARV+PVIE+IHR APQ+ LSIDTYKAEVAR+AI AG Sbjct: 61 ADIIDIGGESTRPGHEPVGASEELARVIPVIEAIHRHAPQIPLSIDTYKAEVARQAIGAG 120 Query: 120 AHIINDVWGAKADPDMAPVAAEAGCPVILMHNRRERNYRELVSDMCADLGDSVKQALAAG 179 AHIIND+WG K DPDM AAE GCPVILMHNRRERNY L+ D+ DL +SV+ A AG Sbjct: 121 AHIINDIWGFKDDPDMPKTAAELGCPVILMHNRRERNYTNLIEDVKRDLLESVEIARTAG 180 Query: 180 VKRENIILDPGIGFAKDYAENLQTMMNLDRLTELGYPLLLATSRKKFIRTVLDLPPDDVV 239 V+ I+LDPGIGFAKDY EN++ M +LD+L LG+P+LLATSRK+FI+T L P DV+ Sbjct: 181 VQDHQILLDPGIGFAKDYDENMKVMASLDQLVGLGFPVLLATSRKRFIQTALGAPAQDVL 240 Query: 240 EGTAATVAFGIAQGCQIVRVHDVARIKRTVQMCDAMLYAAAPL 282 EGTAATVA+GIAQGCQIVRVHDV +KRT +MCDAM YA+ L Sbjct: 241 EGTAATVAYGIAQGCQIVRVHDVKHMKRTAKMCDAMTYASTEL 283 >B1DID3.1 B1DID3_9BACL Dihydropteroate synthase EC=2.5.1.15 Length = 295 Score = 339 bits (870), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 174/282 (61%), Positives = 208/282 (73%), Gaps = 1/282 (0%) Query: 2 RPLIYKRNYRL-GAAELALGERTLIMGILNVTPDSFSDGGLWAEPEKAVEHALQMAEEGA 60 +P + R+Y L G +L LG+RTLIMGILN TPDSFSDGG + E A A M EEG Sbjct: 14 KPTFWNRSYELDGGIKLELGKRTLIMGILNATPDSFSDGGRYNHAEAAAARAAAMVEEGV 73 Query: 61 DIIDIGGESTRPGHQPVGLEEELARVLPVIESIHRAAPQLVLSIDTYKAEVARRAIQAGA 120 DIIDIG ESTRPG +PV +EEEL R+LPVI ++ AAP + +SIDTYKAE AR+A++AGA Sbjct: 74 DIIDIGAESTRPGFEPVSVEEELRRLLPVIRAVREAAPHVPISIDTYKAETARQALEAGA 133 Query: 121 HIINDVWGAKADPDMAPVAAEAGCPVILMHNRRERNYRELVSDMCADLGDSVKQALAAGV 180 HIIND+WG K DP MA VAAE GCPV++ HNR R+Y +LV D+ ADL SV AL AGV Sbjct: 134 HIINDIWGLKYDPFMAAVAAEYGCPVVISHNRPARDYGDLVPDVLADLQASVAIALQAGV 193 Query: 181 KRENIILDPGIGFAKDYAENLQTMMNLDRLTELGYPLLLATSRKKFIRTVLDLPPDDVVE 240 + I LDPG+GFAKD+ +NL+ M L LT LGYP+LL TSRK+FIR LDLP D++ E Sbjct: 194 EASEIWLDPGLGFAKDHDDNLELMGRLSELTALGYPVLLGTSRKRFIRQTLDLPVDELAE 253 Query: 241 GTAATVAFGIAQGCQIVRVHDVARIKRTVQMCDAMLYAAAPL 282 GTAAT A GIAQGCQIVRVHDV KRT M DA++Y + L Sbjct: 254 GTAATTALGIAQGCQIVRVHDVRANKRTAMMTDAIMYNSKNL 295 >A7GJY4.1 A7GJY4_BACCN Dihydropteroate synthase EC=2.5.1.15 Length = 277 Score = 334 bits (856), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 168/272 (61%), Positives = 207/272 (76%), Gaps = 3/272 (1%) Query: 7 KRNY--RLGAAELALGERTLIMGILNVTPDSFSDGGLWAEPEKAVEHALQMAEEGADIID 64 K NY R G L L E+TL+MGILNVTPDSFSDGG + E E AV HA +M GAD+ID Sbjct: 2 KWNYDLRCGEYTLNLNEKTLVMGILNVTPDSFSDGGSYNELETAVRHAKEMVSSGADLID 61 Query: 65 IGGESTRPGHQPVGLEEELARVLPVIESIHRAAPQLVLSIDTYKAEVARRAIQAGAHIIN 124 IGGESTRPG V +EEELARVLPVI+++ + + +SIDTYKAEVA++AI+AGAHIIN Sbjct: 62 IGGESTRPGFAKVSVEEELARVLPVIQAVSKKV-NVPISIDTYKAEVAKQAIEAGAHIIN 120 Query: 125 DVWGAKADPDMAPVAAEAGCPVILMHNRRERNYRELVSDMCADLGDSVKQALAAGVKREN 184 D+WGAKA+P +A VAA P+ILMHNR NYR ++SDM ADL +SVK A AGV+ EN Sbjct: 121 DIWGAKAEPKIAEVAAHYDVPIILMHNRDHTNYRNVMSDMIADLYESVKIAKNAGVRDEN 180 Query: 185 IILDPGIGFAKDYAENLQTMMNLDRLTELGYPLLLATSRKKFIRTVLDLPPDDVVEGTAA 244 IILDPGIGFAK +NL+ M NL++L LGYP+LLATSRK FI VLDLP ++ +EGT A Sbjct: 181 IILDPGIGFAKTPEQNLEVMRNLEQLNVLGYPVLLATSRKSFIGHVLDLPVEERIEGTGA 240 Query: 245 TVAFGIAQGCQIVRVHDVARIKRTVQMCDAML 276 +V GIA+GC+++RVHDV + R +M DAM+ Sbjct: 241 SVCLGIAKGCEMIRVHDVKEMARMAKMMDAMI 272 >C2Q612.1 C2Q612_BACCE Dihydropteroate synthase Length = 277 Score = 330 bits (845), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 166/275 (60%), Positives = 205/275 (74%), Gaps = 1/275 (0%) Query: 6 YKRNYRLGAAELALGERTLIMGILNVTPDSFSDGGLWAEPEKAVEHALQMAEEGADIIDI 65 + + R G L L E+TLIMGILNVTPDSFSDGG + E E AV HA +M +EGA IIDI Sbjct: 3 WDYDLRCGEYTLNLNEKTLIMGILNVTPDSFSDGGSYNEVEAAVRHAKEMRDEGAHIIDI 62 Query: 66 GGESTRPGHQPVGLEEELARVLPVIESIHRAAPQLVLSIDTYKAEVARRAIQAGAHIIND 125 GGESTRPG V +EEE+ RV+P+I+++ + +L +SIDTYKAEVA++AI+AGAHIIND Sbjct: 63 GGESTRPGFAKVSVEEEIKRVVPMIKAVSKEV-KLPISIDTYKAEVAKQAIEAGAHIIND 121 Query: 126 VWGAKADPDMAPVAAEAGCPVILMHNRRERNYRELVSDMCADLGDSVKQALAAGVKRENI 185 +WGAKA+P +A VAA P+ILMHNR NYR L++DM ADL DS+K A AGV+ ENI Sbjct: 122 IWGAKAEPKIAEVAAHYNVPIILMHNRDNMNYRNLMADMIADLHDSIKIAKDAGVRDENI 181 Query: 186 ILDPGIGFAKDYAENLQTMMNLDRLTELGYPLLLATSRKKFIRTVLDLPPDDVVEGTAAT 245 ILDPGIGFAK +NL+ M NLD+L LGYP+LL TSRK FI VLDLP ++ +EGT AT Sbjct: 182 ILDPGIGFAKTPEQNLEAMRNLDQLNVLGYPVLLGTSRKSFIGHVLDLPVEERLEGTGAT 241 Query: 246 VAFGIAQGCQIVRVHDVARIKRTVQMCDAMLYAAA 280 V GI +GC+ VRVHDV + R +M DAM+ A Sbjct: 242 VCLGIEKGCEFVRVHDVKEMARMAKMMDAMIGKGA 276 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,620,905,839 Number of extensions: 64780719 Number of successful extensions: 188571 Number of sequences better than 1.0e-05: 2018 Number of HSP's gapped: 183218 Number of HSP's successfully gapped: 2073 Length of query: 285 Length of database: 3,060,696,203 Length adjustment: 134 Effective length of query: 151 Effective length of database: 1,798,280,193 Effective search space: 271540309143 Effective search space used: 271540309143 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 130 (54.7 bits)