BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0030.p (203 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K346.1 B3K346_9BACI Imidazoleglycerol-phosphate dehydratase EC... 362 8e-99 B1DKX2.1 B1DKX2_9BACL Imidazoleglycerol-phosphate dehydratase EC... 361 2e-98 A6CND7.1 A6CND7_9BACI Imidazoleglycerol-phosphate dehydratase EC... 330 5e-89 Q65EG0.1 HIS7_BACLD Imidazoleglycerol-phosphate dehydratase EC=4... 328 1e-88 O34683.1 HIS7_BACSU Imidazoleglycerol-phosphate dehydratase EC=4... 327 3e-88 >B3K346.1 B3K346_9BACI Imidazoleglycerol-phosphate dehydratase EC=4.2.1.19 Length = 201 Score = 362 bits (930), Expect = 8e-99, Method: Compositional matrix adjust. Identities = 170/196 (86%), Positives = 181/196 (92%) Query: 8 GAVRKAGLSRKTNETDIKLSLAVDGSGVSELETDVPFLNHMLDLFTKHGQFDLSVQARGD 67 A R AG+SRKTNETDI L VDG+G+SELETDVPFLNHMLDLFTKHGQFDL V+A+GD Sbjct: 6 AAARSAGVSRKTNETDIALDFNVDGTGISELETDVPFLNHMLDLFTKHGQFDLRVKAKGD 65 Query: 68 IDIDDHHTVEDIGICLGQAFREALGDKKGIKRYANVFIPMDEALAQVVIDISNRPHFEYR 127 I+IDDHHTVEDIGICLGQ FREALGDKKGIKRYA+VF+PMDEALAQV++DISNRPHFEYR Sbjct: 66 IEIDDHHTVEDIGICLGQTFREALGDKKGIKRYASVFVPMDEALAQVIVDISNRPHFEYR 125 Query: 128 ATYPSQQVGSFSTELVHEFLWKFALEARITLHVIVHYGSNTHHMIEAVFKALGRALDEAT 187 A YPSQQVGSF TELVHEFLWK ALEARITLHVIVHYG NTHHMIEAVFKALGRALDEAT Sbjct: 126 AEYPSQQVGSFHTELVHEFLWKLALEARITLHVIVHYGHNTHHMIEAVFKALGRALDEAT 185 Query: 188 LIDPRVKGVPSTKGVL 203 +DPRV GVPSTKGVL Sbjct: 186 TVDPRVTGVPSTKGVL 201 >B1DKX2.1 B1DKX2_9BACL Imidazoleglycerol-phosphate dehydratase EC=4.2.1.19 Length = 198 Score = 361 bits (926), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 170/197 (86%), Positives = 183/197 (92%) Query: 7 AGAVRKAGLSRKTNETDIKLSLAVDGSGVSELETDVPFLNHMLDLFTKHGQFDLSVQARG 66 A RKA ++RKTNETDIKLS AVDGSG ++LETDVPFLNHMLDLF KHGQFDL+V+ARG Sbjct: 2 ADTKRKAEIARKTNETDIKLSFAVDGSGEAKLETDVPFLNHMLDLFAKHGQFDLTVEARG 61 Query: 67 DIDIDDHHTVEDIGICLGQAFREALGDKKGIKRYANVFIPMDEALAQVVIDISNRPHFEY 126 DIDIDDHHTVEDIGICLGQ REALGDK+GIKRYA+VF+PMDEALAQV+ID+SNRPHFEY Sbjct: 62 DIDIDDHHTVEDIGICLGQTLREALGDKRGIKRYASVFVPMDEALAQVIIDVSNRPHFEY 121 Query: 127 RATYPSQQVGSFSTELVHEFLWKFALEARITLHVIVHYGSNTHHMIEAVFKALGRALDEA 186 RA YPS QVGSFSTELVHEFLWK ALEARITLHVIVHYG NTHHMIEAVFKALGRA+DEA Sbjct: 122 RAEYPSAQVGSFSTELVHEFLWKLALEARITLHVIVHYGKNTHHMIEAVFKALGRAIDEA 181 Query: 187 TLIDPRVKGVPSTKGVL 203 T IDPRV+GVPSTKGVL Sbjct: 182 TSIDPRVQGVPSTKGVL 198 >A6CND7.1 A6CND7_9BACI Imidazoleglycerol-phosphate dehydratase EC=4.2.1.19 Length = 197 Score = 330 bits (846), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 150/193 (77%), Positives = 174/193 (90%) Query: 11 RKAGLSRKTNETDIKLSLAVDGSGVSELETDVPFLNHMLDLFTKHGQFDLSVQARGDIDI 70 R+A L RKTNETDI+LS ++DG+G + +ET VPF++HMLDLFTKHGQFDL+V A+GDID+ Sbjct: 5 RRAELVRKTNETDIELSFSIDGTGNANIETGVPFMSHMLDLFTKHGQFDLNVNAQGDIDV 64 Query: 71 DDHHTVEDIGICLGQAFREALGDKKGIKRYANVFIPMDEALAQVVIDISNRPHFEYRATY 130 DDHHT EDIGICLGQA ++ALGDKKGIKRY N F+PMDEALAQVV+D+SNRPH E RA + Sbjct: 65 DDHHTTEDIGICLGQALQKALGDKKGIKRYGNAFVPMDEALAQVVVDLSNRPHLEMRADF 124 Query: 131 PSQQVGSFSTELVHEFLWKFALEARITLHVIVHYGSNTHHMIEAVFKALGRALDEATLID 190 PSQ+VG+F TELVHEFLWK ALEAR+ LHVIVHYG NTHHMIEAVFKALGRALDEAT ID Sbjct: 125 PSQKVGTFDTELVHEFLWKLALEARMNLHVIVHYGHNTHHMIEAVFKALGRALDEATTID 184 Query: 191 PRVKGVPSTKGVL 203 PR++GVPSTKG+L Sbjct: 185 PRIQGVPSTKGML 197 >Q65EG0.1 HIS7_BACLD Imidazoleglycerol-phosphate dehydratase EC=4.2.1.19 Length = 194 Score = 328 bits (842), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 147/194 (75%), Positives = 175/194 (90%) Query: 10 VRKAGLSRKTNETDIKLSLAVDGSGVSELETDVPFLNHMLDLFTKHGQFDLSVQARGDID 69 +RKA +RKTNETDIKLS +DG G ++++TDVPF+ HMLDLFTKHGQFDLS++A+GD++ Sbjct: 1 MRKAERARKTNETDIKLSFHIDGEGKADIQTDVPFMTHMLDLFTKHGQFDLSIEAKGDVE 60 Query: 70 IDDHHTVEDIGICLGQAFREALGDKKGIKRYANVFIPMDEALAQVVIDISNRPHFEYRAT 129 IDDHHT EDIGICLGQA EALGDK+GIKRY + +PMDEALAQV ID+SNRPH E+RA Sbjct: 61 IDDHHTTEDIGICLGQALLEALGDKQGIKRYGSSMVPMDEALAQVAIDLSNRPHLEFRAE 120 Query: 130 YPSQQVGSFSTELVHEFLWKFALEARITLHVIVHYGSNTHHMIEAVFKALGRALDEATLI 189 +PS+++G+F TELVHEFLWKFALEAR+ LHVIVHYG+NTHHMIEA+FKALGRALDEA LI Sbjct: 121 FPSRKIGTFDTELVHEFLWKFALEARMNLHVIVHYGTNTHHMIEAIFKALGRALDEAALI 180 Query: 190 DPRVKGVPSTKGVL 203 DPRVKG+PSTKG+L Sbjct: 181 DPRVKGIPSTKGML 194 >O34683.1 HIS7_BACSU Imidazoleglycerol-phosphate dehydratase EC=4.2.1.19 Length = 194 Score = 327 bits (838), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 149/194 (76%), Positives = 172/194 (88%) Query: 10 VRKAGLSRKTNETDIKLSLAVDGSGVSELETDVPFLNHMLDLFTKHGQFDLSVQARGDID 69 +RKA RKTNETDI+L+ +DG G ++++TDVPF+ HMLDLFTKHGQFDLS+ A+GD+D Sbjct: 1 MRKAERVRKTNETDIELAFTIDGGGQADIKTDVPFMTHMLDLFTKHGQFDLSINAKGDVD 60 Query: 70 IDDHHTVEDIGICLGQAFREALGDKKGIKRYANVFIPMDEALAQVVIDISNRPHFEYRAT 129 IDDHHT EDIGICLGQA EALGDKKGIKRY + F+PMDEALAQVVID+SNRPH E RA Sbjct: 61 IDDHHTTEDIGICLGQALLEALGDKKGIKRYGSAFVPMDEALAQVVIDLSNRPHLEMRAD 120 Query: 130 YPSQQVGSFSTELVHEFLWKFALEARITLHVIVHYGSNTHHMIEAVFKALGRALDEATLI 189 +P+ +VG+F TELVHEFLWK ALEAR+ LHVIVHYG+NTHHMIEAVFKALGRALDEAT I Sbjct: 121 FPAAKVGTFDTELVHEFLWKLALEARMNLHVIVHYGTNTHHMIEAVFKALGRALDEATTI 180 Query: 190 DPRVKGVPSTKGVL 203 DPRVKG+PSTKG+L Sbjct: 181 DPRVKGIPSTKGML 194 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,145,785,136 Number of extensions: 45182773 Number of successful extensions: 96220 Number of sequences better than 1.0e-05: 1374 Number of HSP's gapped: 94366 Number of HSP's successfully gapped: 1376 Length of query: 203 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 74 Effective length of database: 1,845,385,268 Effective search space: 136558509832 Effective search space used: 136558509832 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)