BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0029.p (207 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K347.1 B3K347_9BACI Imidazole glycerol phosphate synthase, glu... 308 1e-82 B1DKX3.1 B1DKX3_9BACL Imidazole glycerol phosphate synthase, glu... 294 3e-78 Q2B722.1 Q2B722_9BACI Imidazole glycerol phosphate synthase subu... 226 9e-58 A8W0V6.1 A8W0V6_9BACI Acyl-CoA dehydrogenase domain protein 223 6e-57 C0Z6P6.1 C0Z6P6_BREBN Imidazole glycerol phosphate synthase subu... 223 1e-56 >B3K347.1 B3K347_9BACI Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Length = 202 Score = 308 bits (790), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 153/202 (75%), Positives = 173/202 (85%), Gaps = 1/202 (0%) Query: 1 MTVAIVDYGMGNLHSVSKAVERLGYKSLVTGKAGEILAADSVILPGVGAFGDAMEHLRES 60 M +AIVDYGMGNLHSVSKAVERLGY+ LVTG+ E+LAAD +ILPGVGAFGDAME LRE+ Sbjct: 1 MAIAIVDYGMGNLHSVSKAVERLGYQPLVTGEREELLAADGIILPGVGAFGDAMEQLREA 60 Query: 61 GLDAVVQEAAASGQPLLGICLGMQLLFSSSEEYGTHEGLNLLPGSVVRFAPREGYKVPHM 120 LD+V++EAA SG+PLLGICLGMQLLFS SEE+G +EGL++LPGSVVRFA + YKVPHM Sbjct: 61 SLDSVMKEAAESGKPLLGICLGMQLLFSRSEEHGKYEGLDILPGSVVRFAGGD-YKVPHM 119 Query: 121 GWNKLDFLQPQSPLFTGLEAGHVYFVHSFHAIMAQQSDLLAVTDYGHPVTAIVGRENVYG 180 GWN L F + + PLF GLE GHVYFVHS+H + QSDLLAVTDYG PVTAIVGR +VYG Sbjct: 120 GWNSLQFRKREHPLFAGLEEGHVYFVHSYHVLPEVQSDLLAVTDYGQPVTAIVGRGSVYG 179 Query: 181 MQFHPEKSGELGMKLLGNFLKL 202 MQFHPEKSGELGM LL NFL L Sbjct: 180 MQFHPEKSGELGMSLLRNFLAL 201 >B1DKX3.1 B1DKX3_9BACL Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Length = 207 Score = 294 bits (752), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 147/202 (72%), Positives = 164/202 (81%), Gaps = 2/202 (0%) Query: 3 VAIVDYGMGNLHSVSKAVERLGYKSLVTGKAGEILAADSVILPGVGAFGDAMEHLRESGL 62 +AI+DYGMGNLHSVSKAVERLGY+++VT I +AD ILPGVGAFGDAME+LRE+ L Sbjct: 2 IAIIDYGMGNLHSVSKAVERLGYEAVVTADPAVIASADGAILPGVGAFGDAMENLRETKL 61 Query: 63 DAVVQEAAASGQPLLGICLGMQLLFSSSEEYGTHEGLNLLPGSVVRFAPREGYKVPHMGW 122 D V + AASG+PLLGICLGMQLLFS SEE+G +EGLNLLPG V+RF + YKVPHMGW Sbjct: 62 DEVTKAYAASGKPLLGICLGMQLLFSESEEHGVNEGLNLLPGKVIRF--QGDYKVPHMGW 119 Query: 123 NKLDFLQPQSPLFTGLEAGHVYFVHSFHAIMAQQSDLLAVTDYGHPVTAIVGRENVYGMQ 182 NKL FLQ SPLF GLE GHVYFVHSFHA SDLLA TDY VTAIVGR NV+GMQ Sbjct: 120 NKLSFLQSDSPLFKGLEEGHVYFVHSFHAKPEVASDLLATTDYYQQVTAIVGRGNVHGMQ 179 Query: 183 FHPEKSGELGMKLLGNFLKLKG 204 FHPEKS +LG+KLLGNFL L G Sbjct: 180 FHPEKSSDLGIKLLGNFLALTG 201 >Q2B722.1 Q2B722_9BACI Imidazole glycerol phosphate synthase subunit HisH EC=2.4.2.- Length = 212 Score = 226 bits (576), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 114/204 (55%), Positives = 143/204 (70%), Gaps = 5/204 (2%) Query: 3 VAIVDYGMGNLHSVSKAVERLGYKSLVTGKAGEILAADSVILPGVGAFGDAMEHLRESGL 62 + I+DYGMGNL SVSKA+ERL ++ E+ AD +ILPGVG+F DAM+ L +GL Sbjct: 2 IGIIDYGMGNLFSVSKALERLEVPYFLSEDQEELKKADGLILPGVGSFKDAMDRLNATGL 61 Query: 63 DAVVQEAAASGQPLLGICLGMQLLFSSSEEYGTHEGLNLLPGSVVRF----APREGYKVP 118 ++QE A+G+PL GICLGMQLLF SSEE G EGL LLPG VVRF RE YKVP Sbjct: 62 TGMIQEYTAAGKPLAGICLGMQLLFESSEENGYSEGLKLLPGKVVRFPGEDEQREKYKVP 121 Query: 119 HMGWNKLDFLQPQSPLFTGLEAGHVYFVHSFHAIMAQQSDLLAVTDYGHPVTAIVGRENV 178 HMGWN+L+F+ SP+ +E G+VYFVHS++A +LA + Y V A+VGR+NV Sbjct: 122 HMGWNRLEFIN-SSPILKNVEEGYVYFVHSYYAEPGDHDVVLARSFYDREVPAVVGRDNV 180 Query: 179 YGMQFHPEKSGELGMKLLGNFLKL 202 +GMQFHPEKS LGM+LL NF + Sbjct: 181 FGMQFHPEKSSSLGMELLRNFTTI 204 >A8W0V6.1 A8W0V6_9BACI Acyl-CoA dehydrogenase domain protein Length = 206 Score = 223 bits (569), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 111/203 (54%), Positives = 142/203 (69%), Gaps = 2/203 (0%) Query: 3 VAIVDYGMGNLHSVSKAVERLGYKSLVTGKAGEILAADSVILPGVGAFGDAMEHLRESGL 62 + I+DYGMGNLHSV+KAVERLG ++ E+ AD +ILPGVGAF D M+ L + GL Sbjct: 2 IGIIDYGMGNLHSVTKAVERLGRDCFLSEDPEELKKADCLILPGVGAFKDGMDELGKRGL 61 Query: 63 DAVVQEAAASGQPLLGICLGMQLLFSSSEEYGTHEGLNLLPGSVVRFAPREGYKVPHMGW 122 + E G+PLLGICLGMQLLF SEE G +GL++LPG V +F P YKVPHMGW Sbjct: 62 VPFIHEWIEDGKPLLGICLGMQLLFDESEENGPTKGLSVLPGKVKKF-PGGDYKVPHMGW 120 Query: 123 NKLDFLQPQSPLFTGLEAGHVYFVHSFHAIMAQQSDLLAVTDY-GHPVTAIVGRENVYGM 181 N+L F QP P+ GL+ GHVYFVHS+ + ++ L+A +Y G VTA+ GR+NV+G Sbjct: 121 NELTFEQPAHPVLQGLDGGHVYFVHSYFVVADRKEILIASAEYGGEQVTAVAGRDNVWGT 180 Query: 182 QFHPEKSGELGMKLLGNFLKLKG 204 QFHPEKS +GM +L NF++ KG Sbjct: 181 QFHPEKSSVVGMTMLKNFVEYKG 203 >C0Z6P6.1 C0Z6P6_BREBN Imidazole glycerol phosphate synthase subunit HisH EC=2.4.2.- Length = 204 Score = 223 bits (567), Expect = 1e-56, Method: Compositional matrix adjust. Identities = 116/198 (58%), Positives = 144/198 (72%), Gaps = 5/198 (2%) Query: 3 VAIVDYGMGNLHSVSKAVERLGYKSLVTGKAGEILAADSVILPGVGAFGDAMEHLRESGL 62 + I+DYGMGNL+S+SKA+ERLGY +A + +ILPGVGAFGDA+ ++RE GL Sbjct: 2 IGIIDYGMGNLYSLSKALERLGYSYEFVSQAERLQEYSGLILPGVGAFGDAIANIRELGL 61 Query: 63 DAVVQEAAASGQPLLGICLGMQLLFSSSEEYGTHEGLNLLPGSVVRFAPREGYKVPHMGW 122 + ++ AA+G+P+LGICLGMQLLF S E+G H GL LL G VVRF R YKVPHMGW Sbjct: 62 EQAIKGYAATGRPILGICLGMQLLFEKSAEHGEHTGLGLLGGEVVRF--RGDYKVPHMGW 119 Query: 123 NKLDFLQPQSPLFTGLEAG-HVYFVHSFHAIMAQQSDLLAVTDYGHPVTAIVGRENVYGM 181 N+L Q Q PL G++ G +VYFVHS+H ++ + LLA +DY VTAIV R+NVYGM Sbjct: 120 NQLMIKQKQ-PLLNGVQDGDYVYFVHSYH-VLCEPDVLLATSDYHQEVTAIVNRDNVYGM 177 Query: 182 QFHPEKSGELGMKLLGNF 199 QFHPEKSGE GM LL NF Sbjct: 178 QFHPEKSGETGMLLLRNF 195 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.138 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,264,393,562 Number of extensions: 51876142 Number of successful extensions: 146756 Number of sequences better than 1.0e-05: 1445 Number of HSP's gapped: 142830 Number of HSP's successfully gapped: 1451 Length of query: 207 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 78 Effective length of database: 1,845,385,268 Effective search space: 143940050904 Effective search space used: 143940050904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 128 (53.9 bits)