BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0026.p (243 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K350.1 B3K350_9BACI Phosphoribosyl-ATP diphosphatase 340 5e-92 B1DKX5.1 B1DKX5_9BACL Phosphoribosyl-ATP diphosphatase 274 6e-72 B4BN61.1 B4BN61_9BACI Phosphoribosyl-ATP diphosphatase 254 5e-66 A4ISR1.1 A4ISR1_GEOTN Histidine biosynthesis bifunctional protei... 253 1e-65 C5D7N7.1 C5D7N7_9BACI Phosphoribosyl-ATP diphosphatase 253 2e-65 >B3K350.1 B3K350_9BACI Phosphoribosyl-ATP diphosphatase Length = 233 Score = 340 bits (873), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 168/240 (70%), Positives = 191/240 (79%), Gaps = 17/240 (7%) Query: 8 KVLSQQEVLEGIRWNEAGLLPAVVQDADSLEVLMFAYMNKESLQLSLESGQTWFWSRSRG 67 K LS ++V E IRW+ AGL+PA+VQDA+S +VLM AYMN+ESL+L+LESG+TWFWSRSR Sbjct: 7 KDLSLEQVSEHIRWDAAGLVPAIVQDAESKQVLMMAYMNRESLRLTLESGETWFWSRSRE 66 Query: 68 ELWHKGGTSGNTQAITSIHYDCDSDTLLVKVVPEGPACHTGETSCFFRELPLSNPXXXXX 127 ELWHKG TSGN Q + S+ YDCD DTLL++V P GPACHTG+T+CF E+ Sbjct: 67 ELWHKGATSGNVQTVVSMSYDCDGDTLLLQVNPNGPACHTGQTTCFHNEI---------- 116 Query: 128 XXXXPEAVSARPGLNDSA----RFAVLGELERVIAEREAERPEGAYTTYLFDKGVDKILK 183 + + P +A RFAVL ELE VIA+RE ERPEGAYTTYLFDKGVDKILK Sbjct: 117 ---TAQGQDSEPASQGTAASGERFAVLAELEEVIAQREVERPEGAYTTYLFDKGVDKILK 173 Query: 184 KVGEEASETIIAAKNKDNAELRLEVSDLIYHLLVLLQERKLPLDEIMDELSLRHERPRRD 243 KVGEEASETIIAAKNKDNAEL+LEVSDLIYHLLVLLQERKLPLDEIMDELS RHERPRRD Sbjct: 174 KVGEEASETIIAAKNKDNAELKLEVSDLIYHLLVLLQERKLPLDEIMDELSRRHERPRRD 233 >B1DKX5.1 B1DKX5_9BACL Phosphoribosyl-ATP diphosphatase Length = 233 Score = 274 bits (700), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 146/227 (64%), Positives = 172/227 (75%), Gaps = 10/227 (4%) Query: 14 EVLEGIRWNEAGLLPAVVQDADSLEVLMFAYMNKESLQLSLESGQTWFWSRSRGELWHKG 73 ++ E I+W+E GL+PA+VQDA S EVLM AYMNKESL+LS ESG TWFWSRSR ELW+KG Sbjct: 4 QLAELIKWSEDGLVPAIVQDAQSKEVLMLAYMNKESLKLSAESGVTWFWSRSRNELWNKG 63 Query: 74 GTSGNTQAITSIHYDCDSDTLLVKVVPEGPACHTGETSCFFRELPLSNPXXXXXXXXXPE 133 TSG+TQ I S+ YDCD+DTLLV+V +GPACHTG SCFF E+ ++ E Sbjct: 64 ATSGHTQRIRSMSYDCDADTLLVRVDQKGPACHTGSYSCFFNEIEVAG----------AE 113 Query: 134 AVSARPGLNDSARFAVLGELERVIAEREAERPEGAYTTYLFDKGVDKILKKVGEEASETI 193 S + RF +LGELE VIA+R AERPEGAYTTYLF KG+DKILKKVGEEA+E I Sbjct: 114 KSSDSAKASSDDRFGILGELEGVIAQRYAERPEGAYTTYLFGKGLDKILKKVGEEATEAI 173 Query: 194 IAAKNKDNAELRLEVSDLIYHLLVLLQERKLPLDEIMDELSLRHERP 240 IAAKN DN ELR E SDL++HLLVLL+ER LPLDE+M EL RH +P Sbjct: 174 IAAKNGDNDELRSEASDLLFHLLVLLRERGLPLDEVMAELQSRHGKP 220 >B4BN61.1 B4BN61_9BACI Phosphoribosyl-ATP diphosphatase Length = 215 Score = 254 bits (649), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 137/223 (61%), Positives = 166/223 (74%), Gaps = 18/223 (8%) Query: 15 VLEGIRWNEAGLLPAVVQDADSLEVLMFAYMNKESLQLSLESGQTWFWSRSRGELWHKGG 74 ++ IR++E GL+PA+VQDA S EVLM AYMNKESL+ +LE+G+TWF+SRSR ELWHKG Sbjct: 1 MIADIRFDEKGLVPAIVQDAQSKEVLMLAYMNKESLEKTLETGETWFYSRSRQELWHKGA 60 Query: 75 TSGNTQAITSIHYDCDSDTLLVKVVPEGPACHTGETSCFFRELPLSNPXXXXXXXXXPEA 134 TSGN Q + I YDCD+DTLLV V P GPACHTG SCF R L Sbjct: 61 TSGNVQRVVDIRYDCDADTLLVLVEPAGPACHTGSYSCFSRSLN---------------- 104 Query: 135 VSARPGLNDSARFAVLGELERVIAEREAERPEGAYTTYLFDKGVDKILKKVGEEASETII 194 AR D RFA+L ELE++IA+R+AERPEGAYTTYLF+KGVDKILKKVGEEA+E II Sbjct: 105 GEARTPTAD--RFAILNELEQIIAQRDAERPEGAYTTYLFEKGVDKILKKVGEEAAEVII 162 Query: 195 AAKNKDNAELRLEVSDLIYHLLVLLQERKLPLDEIMDELSLRH 237 AAKN+ + EL+ E +DL+YHLLVLL+E+KLPLD ++ L RH Sbjct: 163 AAKNRSHDELKWEAADLLYHLLVLLREQKLPLDAVLATLVERH 205 >A4ISR1.1 A4ISR1_GEOTN Histidine biosynthesis bifunctional protein (Phosphoribosyl-AMP cyclohydrolase/phosphorribosyl-ATPpyrophosphohydrolase) Length = 215 Score = 253 bits (645), Expect = 1e-65, Method: Compositional matrix adjust. Identities = 136/223 (60%), Positives = 165/223 (73%), Gaps = 18/223 (8%) Query: 15 VLEGIRWNEAGLLPAVVQDADSLEVLMFAYMNKESLQLSLESGQTWFWSRSRGELWHKGG 74 ++ IR++E GL+PA+VQDA S EVLM AYMNKESL+ +LE+G+TWF+SRSR ELWHKG Sbjct: 1 MIADIRFDEKGLVPAIVQDAQSKEVLMLAYMNKESLEKTLETGETWFYSRSRQELWHKGA 60 Query: 75 TSGNTQAITSIHYDCDSDTLLVKVVPEGPACHTGETSCFFRELPLSNPXXXXXXXXXPEA 134 TSGN Q + I YDCD+DTLLV V P GPACHTG SCF R L Sbjct: 61 TSGNVQRVVDIRYDCDADTLLVLVEPAGPACHTGSYSCFSRSLN---------------- 104 Query: 135 VSARPGLNDSARFAVLGELERVIAEREAERPEGAYTTYLFDKGVDKILKKVGEEASETII 194 AR D RF +L ELE++IA+R+AERPEGAYTTYLF+KGVDKILKKVGEEA+E II Sbjct: 105 GEARTPTAD--RFTILNELEQIIAQRDAERPEGAYTTYLFEKGVDKILKKVGEEAAEVII 162 Query: 195 AAKNKDNAELRLEVSDLIYHLLVLLQERKLPLDEIMDELSLRH 237 AAKN+ + EL+ E +DL+YHLLVLL+E+KLPLD ++ L RH Sbjct: 163 AAKNRSHDELKWEAADLLYHLLVLLREQKLPLDAVLATLVERH 205 >C5D7N7.1 C5D7N7_9BACI Phosphoribosyl-ATP diphosphatase Length = 210 Score = 253 bits (645), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 135/222 (60%), Positives = 165/222 (74%), Gaps = 18/222 (8%) Query: 16 LEGIRWNEAGLLPAVVQDADSLEVLMFAYMNKESLQLSLESGQTWFWSRSRGELWHKGGT 75 L IR++E GL+PA+VQDA S EVLM AYMN+ESL+ SLE+G+TWF+SRSRGELWHKG T Sbjct: 3 LANIRFDEKGLVPAIVQDAQSKEVLMLAYMNEESLKKSLETGETWFYSRSRGELWHKGAT 62 Query: 76 SGNTQAITSIHYDCDSDTLLVKVVPEGPACHTGETSCFFRELPLSNPXXXXXXXXXPEAV 135 SGNTQ I + YDCD+D LLV V P GPACHTG SCF + E Sbjct: 63 SGNTQRIVEMRYDCDNDALLVLVEPAGPACHTGSYSCFSNRI-------------NGEKY 109 Query: 136 SARPGLNDSARFAVLGELERVIAEREAERPEGAYTTYLFDKGVDKILKKVGEEASETIIA 195 A P RFA++ LE +IA+R+AERPEGAYTTYL +KGVDKILKKVGEEA+E IIA Sbjct: 110 EASPN-----RFAIINTLEEIIAKRDAERPEGAYTTYLLEKGVDKILKKVGEEAAEVIIA 164 Query: 196 AKNKDNAELRLEVSDLIYHLLVLLQERKLPLDEIMDELSLRH 237 AKN+ + EL+ EV+DL+YHLLVLL+E+KLPLD +++ L+ RH Sbjct: 165 AKNRSHDELKWEVADLLYHLLVLLREQKLPLDAVLEVLTKRH 206 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.314 0.132 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,345,800,829 Number of extensions: 52298328 Number of successful extensions: 109068 Number of sequences better than 1.0e-05: 1857 Number of HSP's gapped: 108175 Number of HSP's successfully gapped: 2001 Length of query: 243 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 111 Effective length of database: 1,817,122,223 Effective search space: 201700566753 Effective search space used: 201700566753 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 129 (54.3 bits)