BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0024.p (314 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K352.1 B3K352_9BACI Ribose-phosphate pyrophosphokinase EC=2.7.6.1 507 e-142 B1DKX7.1 B1DKX7_9BACL Ribose-phosphate pyrophosphokinase EC=2.7.6.1 496 e-139 B1D7P0.1 B1D7P0_9BACL Ribose-phosphate pyrophosphokinase EC=2.7.6.1 423 e-116 C4C9V5.1 C4C9V5_9ACTN Ribose-phosphate pyrophosphokinase EC=2.7.6.1 333 8e-90 C1SC08.1 C1SC08_9ACTN Ribose-phosphate pyrophosphokinase EC=2.7.6.1 332 4e-89 >B3K352.1 B3K352_9BACI Ribose-phosphate pyrophosphokinase EC=2.7.6.1 Length = 316 Score = 507 bits (1305), Expect = e-142, Method: Compositional matrix adjust. Identities = 246/312 (78%), Positives = 279/312 (89%), Gaps = 1/312 (0%) Query: 4 LRIFSGSSNPKLAADIAERLGAPLGQIKLTRFKSGEIYVHYEESIRNCDVFLVQSLAHPI 63 LR+F+G+SNP LAA I+++LG LG+IK++RF+SGE+YVHYEESIRNCDVFL+QS +HPI Sbjct: 5 LRLFAGTSNPALAASISQQLGVELGKIKISRFQSGEVYVHYEESIRNCDVFLLQSFSHPI 64 Query: 64 NELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAGATR 123 NE+FVELLVMIDAAKRASART+NIIVPYYGYARQERK+APREPISAKMVADVLTTAGA R Sbjct: 65 NEMFVELLVMIDAAKRASARTINIIVPYYGYARQERKAAPREPISAKMVADVLTTAGANR 124 Query: 124 VITIDLHAAAIQGFFNIPVDHLTALDLISGYLKVKGLSDLVVVSPDAGRASMAEKLASRL 183 VITIDLHA AIQGFFNIPVDHLTALDLI+ YLK K + + V+VSPDAGRA AEKL+SRL Sbjct: 125 VITIDLHAPAIQGFFNIPVDHLTALDLITEYLKSKNIENPVIVSPDAGRAKTAEKLSSRL 184 Query: 184 DSPFAIMIKKRPAHNESVITHVIGDVEGRTPIIIEDLIDTGTTIVNVVEGLKERGARNSI 243 SPFA+M+K+RPAHNE+VITHVIGDV GRTPIIIEDLIDTGTTIV VVE LKERGA ++I Sbjct: 185 GSPFAMMVKQRPAHNEAVITHVIGDVAGRTPIIIEDLIDTGTTIVQVVESLKERGANDAI 244 Query: 244 VCATHGLFSGDALSRMVHPNIDEIVVTDSIALPDDHSS-RFTVLSVAPMLAEATRIIIEG 302 VCATHGLFSG+AL R+ H +I+EIVVTDSI LPD H R VLSVAPMLA+AT IIIEG Sbjct: 245 VCATHGLFSGEALDRLDHAHIEEIVVTDSIVLPDHHCKMRLKVLSVAPMLAQATHIIIEG 304 Query: 303 GSIDKLFIDAGI 314 GSI LF DAG+ Sbjct: 305 GSIATLFKDAGV 316 >B1DKX7.1 B1DKX7_9BACL Ribose-phosphate pyrophosphokinase EC=2.7.6.1 Length = 317 Score = 496 bits (1278), Expect = e-139, Method: Compositional matrix adjust. Identities = 244/311 (78%), Positives = 272/311 (87%) Query: 3 QLRIFSGSSNPKLAADIAERLGAPLGQIKLTRFKSGEIYVHYEESIRNCDVFLVQSLAHP 62 +LRIFSGSSNP LA IA LG LG IK++RFKSGEIYVHYEE+IRNCDVFLVQS +HP Sbjct: 5 KLRIFSGSSNPALAQKIAGDLGLTLGAIKMSRFKSGEIYVHYEETIRNCDVFLVQSFSHP 64 Query: 63 INELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAGAT 122 INE FVELLVMIDAAKRASA+T+NII+PYYGYARQERK+APREPISAKMVADVLTT GA Sbjct: 65 INEHFVELLVMIDAAKRASAKTINIIMPYYGYARQERKAAPREPISAKMVADVLTTVGAN 124 Query: 123 RVITIDLHAAAIQGFFNIPVDHLTALDLISGYLKVKGLSDLVVVSPDAGRASMAEKLASR 182 RVITIDLHA AIQGFFNIPVDH+TALDL+S YLK K + + VVVSPDAGRAS AEKLA+ Sbjct: 125 RVITIDLHAPAIQGFFNIPVDHMTALDLLSDYLKSKNIQNPVVVSPDAGRASTAEKLANN 184 Query: 183 LDSPFAIMIKKRPAHNESVITHVIGDVEGRTPIIIEDLIDTGTTIVNVVEGLKERGARNS 242 LD+ FAIMIKKRPAHNES ITHVIGDVEG+T IIIEDLIDTG+TIVNVVE LKERGA+ Sbjct: 185 LDTSFAIMIKKRPAHNESSITHVIGDVEGQTAIIIEDLIDTGSTIVNVVESLKERGAKEV 244 Query: 243 IVCATHGLFSGDALSRMVHPNIDEIVVTDSIALPDDHSSRFTVLSVAPMLAEATRIIIEG 302 VCATH LFSG+A+ R+ HP+I EI+VTDSI+LP++ +FTVLSVAP+LAEATRIIIEG Sbjct: 245 YVCATHPLFSGNAIERLNHPHIKEIIVTDSISLPENRPDKFTVLSVAPLLAEATRIIIEG 304 Query: 303 GSIDKLFIDAG 313 GSI LF G Sbjct: 305 GSISTLFKTNG 315 >B1D7P0.1 B1D7P0_9BACL Ribose-phosphate pyrophosphokinase EC=2.7.6.1 Length = 314 Score = 423 bits (1087), Expect = e-116, Method: Compositional matrix adjust. Identities = 202/309 (65%), Positives = 252/309 (81%) Query: 1 MHQLRIFSGSSNPKLAADIAERLGAPLGQIKLTRFKSGEIYVHYEESIRNCDVFLVQSLA 60 M ++IFSGSSN LA ++ +L PLG I+++R SGEI + Y ESIR+ V+++QSL+ Sbjct: 1 MQNVKIFSGSSNRPLAEELCRKLNVPLGDIEISRQASGEISLRYIESIRSAHVYIIQSLS 60 Query: 61 HPINELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAG 120 HP+NE VEL++MIDAAKRASA+T+NII+PYYGYARQERKSAPREPISAK+VADVLTT G Sbjct: 61 HPVNEHLVELMIMIDAAKRASAKTINIIMPYYGYARQERKSAPREPISAKLVADVLTTVG 120 Query: 121 ATRVITIDLHAAAIQGFFNIPVDHLTALDLISGYLKVKGLSDLVVVSPDAGRASMAEKLA 180 A R+IT+DLHA IQGFF IPVDH+TALDLI+ YLK K + + VVVSPDAGRA+ AEKLA Sbjct: 121 ADRLITVDLHADPIQGFFEIPVDHITALDLITDYLKSKNIKNPVVVSPDAGRATTAEKLA 180 Query: 181 SRLDSPFAIMIKKRPAHNESVITHVIGDVEGRTPIIIEDLIDTGTTIVNVVEGLKERGAR 240 + +D PFAIMIK RPAHN S ITH+IG+VEG TPIIIEDLIDTG TI+ VVE L +RGA Sbjct: 181 NYMDCPFAIMIKNRPAHNTSKITHIIGEVEGMTPIIIEDLIDTGGTIIKVVEALNKRGAN 240 Query: 241 NSIVCATHGLFSGDALSRMVHPNIDEIVVTDSIALPDDHSSRFTVLSVAPMLAEATRIII 300 ++ +CATHGLFS +AL ++ HP I E+V+TD+IA+ +HS +F VL +A +LA A RII Sbjct: 241 DAFICATHGLFSENALEKLTHPFIKEVVITDTIAIDPNHSDKFVVLPMADLLANALRIIN 300 Query: 301 EGGSIDKLF 309 GGSI++LF Sbjct: 301 NGGSINRLF 309 >C4C9V5.1 C4C9V5_9ACTN Ribose-phosphate pyrophosphokinase EC=2.7.6.1 Length = 319 Score = 333 bits (855), Expect = 8e-90, Method: Compositional matrix adjust. Identities = 169/311 (54%), Positives = 226/311 (72%), Gaps = 4/311 (1%) Query: 3 QLRIFSGSSNPKLAADIAERLGAPLGQIKLTRFKSGEIYVHYEESIRNCDVFLVQSLA-H 61 ++ IFSGS NPKLA +IA++LG PLG IK +F +GEIY Y E+IR DVFL+QS+A Sbjct: 8 EMAIFSGSVNPKLAEEIADQLGMPLGNIKHEKFANGEIYCRYLENIRGDDVFLIQSVAGE 67 Query: 62 PINELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAGA 121 IN+ +ELL+MIDAAKRASAR+++ ++ +YGYARQERK++PREPI+AK+VAD+L AG Sbjct: 68 HINDALMELLIMIDAAKRASARSISAVITHYGYARQERKASPREPITAKLVADMLQVAGI 127 Query: 122 TRVITIDLHAAAIQGFFNIPVDHLTALDLISGYLKVKGL--SDLVVVSPDAGRASMAEKL 179 + +ITIDLHAAA QGFFN+PV+H+TAL + Y K KG + L VVSPD GRA A+K+ Sbjct: 128 SNIITIDLHAAATQGFFNVPVNHMTALPIFVDYFKQKGFDPASLCVVSPDVGRAKEAKKM 187 Query: 180 ASRLDSPFAIMIKKRPAHNESVITHVIGDVEGRTPIIIEDLIDTGTTIVNVVEGLKERGA 239 RLDS AIM K RP HN++ IT +IGDVEG+ II +D+IDT ++V LK +GA Sbjct: 188 QMRLDSDIAIMHKDRPRHNQAEITALIGDVEGKICIINDDMIDTAGSLVAAAATLKAKGA 247 Query: 240 RNSIVCATHGLFSGDALSRMVHPNIDEIVVTDSIALP-DDHSSRFTVLSVAPMLAEATRI 298 CATHG+FSG A R+ + I+E+VV+++I +P + + + VLSVAP+LA+ + Sbjct: 248 ERIFACATHGIFSGPAYDRIENSIIEEVVVSNTIPVPLERQTGKIKVLSVAPLLAKTMKA 307 Query: 299 IIEGGSIDKLF 309 E GSI LF Sbjct: 308 AYENGSISALF 318 >C1SC08.1 C1SC08_9ACTN Ribose-phosphate pyrophosphokinase EC=2.7.6.1 Length = 321 Score = 332 bits (850), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 162/311 (52%), Positives = 228/311 (73%), Gaps = 4/311 (1%) Query: 3 QLRIFSGSSNPKLAADIAERLGAPLGQIKLTRFKSGEIYVHYEESIRNCDVFLVQSLA-H 61 ++ IFSG+ NP LA++IA LG LG +++ +F +GEIY Y+ES+R DVF++QS+A Sbjct: 10 RMAIFSGTVNPDLASEIAGELGTTLGNVRIEKFANGEIYARYQESVRGADVFIIQSIAGE 69 Query: 62 PINELFVELLVMIDAAKRASARTVNIIVPYYGYARQERKSAPREPISAKMVADVLTTAGA 121 IN+ +ELL+MIDAAKRASAR+++ +V +YGYARQERK+A REPI+AK+VAD+++ AGA Sbjct: 70 HINDALMELLIMIDAAKRASARSISAVVTHYGYARQERKAASREPITAKLVADLISVAGA 129 Query: 122 TRVITIDLHAAAIQGFFNIPVDHLTALDLISGYLKVKGLS--DLVVVSPDAGRASMAEKL 179 T +I +DLH AIQGFFNIPV+H+TA+ + + Y K KG + +L VVSPD GRA A+K Sbjct: 130 TNMIALDLHQDAIQGFFNIPVNHMTAMSIFADYFKHKGFNPDELCVVSPDVGRAKAAKKF 189 Query: 180 ASRLDSPFAIMIKKRPAHNESVITHVIGDVEGRTPIIIEDLIDTGTTIVNVVEGLKERGA 239 + +DS AIM K RP HN+S IT +IGDVE + II +D+IDTG ++V E LK +GA Sbjct: 190 QTMIDSDIAIMHKDRPRHNQSEITALIGDVEDKICIINDDMIDTGGSLVAAAETLKAKGA 249 Query: 240 RNSIVCATHGLFSGDALSRMVHPNIDEIVVTDSIALP-DDHSSRFTVLSVAPMLAEATRI 298 R CATHGLFSG A R+ + +I+E+VVT+++ +P D + + V+SVAP+ A+ + Sbjct: 250 REVYACATHGLFSGPAYDRIENSSIEEVVVTNAVPVPLDRQTGKIRVVSVAPLFAKTIKN 309 Query: 299 IIEGGSIDKLF 309 + E GS+ LF Sbjct: 310 VYECGSVSALF 320 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,701,842,932 Number of extensions: 65621486 Number of successful extensions: 197013 Number of sequences better than 1.0e-05: 2418 Number of HSP's gapped: 192357 Number of HSP's successfully gapped: 2589 Length of query: 314 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 179 Effective length of database: 1,788,859,178 Effective search space: 320205792862 Effective search space used: 320205792862 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 131 (55.1 bits)