BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0022.p (317 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K354.1 B3K354_9BACI Thioredoxin reductase EC=1.8.1.9 566 e-160 B3KDM6.1 B3KDM6_9BACI Thioredoxin reductase EC=1.8.1.9 513 e-143 Q2BA26.1 Q2BA26_9BACI Thioredoxin reductase EC=1.8.1.9 499 e-139 B1D8P9.1 B1D8P9_9BACL Thioredoxin reductase EC=1.8.1.9 498 e-139 C2VZH1.1 C2VZH1_BACCE Thioredoxin-disulfide reductase 494 e-138 >B3K354.1 B3K354_9BACI Thioredoxin reductase EC=1.8.1.9 Length = 317 Score = 566 bits (1459), Expect = e-160, Method: Compositional matrix adjust. Identities = 265/317 (83%), Positives = 293/317 (92%) Query: 1 MYKTIVIGTGPAGLTAAIYLARANLSPLVIEGLQPGGQLXXXXEVENFPGFPDGILGPDL 60 MYK+IVIGTGPAGLTAAIYLARANL PLVIEG+QPGGQL EVENFPGFP GI+GP+L Sbjct: 1 MYKSIVIGTGPAGLTAAIYLARANLKPLVIEGMQPGGQLTTTTEVENFPGFPQGIMGPEL 60 Query: 61 MDNMRKQAERFGAQFKNGWVEAVDFSQRPFKITVDGLGVLEAETVIISTGASARYLGIPG 120 MDNMR+QAERFGA+FK+ WVE+VDFS+RPFK+ V+G+G L AE+VIISTGASA+YLGIPG Sbjct: 61 MDNMRQQAERFGAEFKSAWVESVDFSERPFKVNVEGMGELLAESVIISTGASAKYLGIPG 120 Query: 121 EQDNVGRGVSTCATCDGFFFRGKKIVVVGGGDSAMEEASFLTRFASSVTLVHRRSELRAS 180 EQ+NVGRGVSTCATCDGFFFRGKKI+V+GGGDSAMEEASFLTRFASSVT+V+RR+ELRAS Sbjct: 121 EQENVGRGVSTCATCDGFFFRGKKIIVIGGGDSAMEEASFLTRFASSVTVVNRRTELRAS 180 Query: 181 KIMQDRVRENSKVAWALNRTPLEVAIGDTGVKGLKVRNNETGAEELVEADGVFVAIGHTP 240 KIMQDR REN K+ WAL+RTP+EV DTGVKGLKVRNNETG EEL+EA+GVFVAIGHTP Sbjct: 181 KIMQDRARENEKIQWALDRTPVEVVTSDTGVKGLKVRNNETGEEELIEAEGVFVAIGHTP 240 Query: 241 NTAFLGGQITTDANGYIVVNPGTTETNIPGVFACGDVQDTRYRQAISAAGTGCMAAMDAE 300 NT FLG QITTD GYI+V PGTTETNIPGVFACGDVQDTRYRQAI+AAGTGCMAAMD E Sbjct: 241 NTGFLGNQITTDPTGYILVKPGTTETNIPGVFACGDVQDTRYRQAITAAGTGCMAAMDCE 300 Query: 301 KYLEGSMVHDWSETLDK 317 KYLEG MVHDWSETL+K Sbjct: 301 KYLEGHMVHDWSETLNK 317 >B3KDM6.1 B3KDM6_9BACI Thioredoxin reductase EC=1.8.1.9 Length = 313 Score = 513 bits (1320), Expect = e-143, Method: Compositional matrix adjust. Identities = 243/309 (78%), Positives = 273/309 (88%), Gaps = 1/309 (0%) Query: 1 MYKTIVIGTGPAGLTAAIYLARANLSPLVIEGLQPGGQLXXXXEVENFPGFPDGILGPDL 60 MYK+++IGTGPAGLTAAIYLARANLSPLVIEG QPGGQL EVENFPGFP+GI+GP+L Sbjct: 1 MYKSVIIGTGPAGLTAAIYLARANLSPLVIEGPQPGGQLTTTTEVENFPGFPEGIMGPEL 60 Query: 61 MDNMRKQAERFGAQFKNGWVEAVDFSQRPFKITVDGLGVLEAETVIISTGASARYLGIPG 120 MDNMR+QAERFGA+F+ GWV +V+F +RPFK+ VDG+G + AET+IISTGA+A+YLGIPG Sbjct: 61 MDNMRQQAERFGAEFRTGWVNSVEFGERPFKLDVDGMGEVVAETLIISTGATAKYLGIPG 120 Query: 121 EQDNVGRGVSTCATCDGFFFRGKKIVVVGGGDSAMEEASFLTRFASSVTLVHRRSELRAS 180 EQDNVGRGVSTCATCDGFFFRGK+IVVVGGGDSA+EEA+FLTRFAS VTLVHRR ELRAS Sbjct: 121 EQDNVGRGVSTCATCDGFFFRGKEIVVVGGGDSALEEANFLTRFASKVTLVHRREELRAS 180 Query: 181 KIMQDRVRENSKVAWALNRTPLEVAIGDTGVKGLKVRNNETGAEELVEADGVFVAIGHTP 240 KIMQDR R N K+ WALNRTP EV +TGVKG+KV NNETG EE + GVFVAIGH P Sbjct: 181 KIMQDRARANEKIEWALNRTPQEVIADETGVKGIKVLNNETGEEETIAVSGVFVAIGHHP 240 Query: 241 NTAFLGGQITTDANGYIVVNPGTTETNIPGVFACGDVQDTRYRQAISAAGTGCMAAMDAE 300 NT FLGG ITTD NGYIV PGT+ETNI GVFACGDVQDTRYRQAI+AAG+GCMAAMDAE Sbjct: 241 NTGFLGGSITTDPNGYIVTTPGTSETNIQGVFACGDVQDTRYRQAITAAGSGCMAAMDAE 300 Query: 301 KYLEGSMVH 309 KY+E S+ H Sbjct: 301 KYIE-SLEH 308 >Q2BA26.1 Q2BA26_9BACI Thioredoxin reductase EC=1.8.1.9 Length = 319 Score = 499 bits (1286), Expect = e-139, Method: Compositional matrix adjust. Identities = 229/317 (72%), Positives = 271/317 (85%) Query: 1 MYKTIVIGTGPAGLTAAIYLARANLSPLVIEGLQPGGQLXXXXEVENFPGFPDGILGPDL 60 M K +++GTGPAGLTAAIYLARAN++P++IEG QPGGQL EVENFPGF DGI+GP+L Sbjct: 1 MEKVVILGTGPAGLTAAIYLARANMNPVIIEGDQPGGQLTLTTEVENFPGFTDGIMGPEL 60 Query: 61 MDNMRKQAERFGAQFKNGWVEAVDFSQRPFKITVDGLGVLEAETVIISTGASARYLGIPG 120 MDNMRKQAERFGA FK GWV DFS++PF++ DG+G +EAE+VI+STGASA+ L IPG Sbjct: 61 MDNMRKQAERFGAVFKRGWVTEADFSKKPFRMKADGIGEIEAESVILSTGASAKLLNIPG 120 Query: 121 EQDNVGRGVSTCATCDGFFFRGKKIVVVGGGDSAMEEASFLTRFASSVTLVHRRSELRAS 180 E+DN+G+GVSTCATCDGFFFRGKK++++GGGDSAMEEA+FLT+FA +VT+VHRR ELRAS Sbjct: 121 EKDNIGKGVSTCATCDGFFFRGKKVLIIGGGDSAMEEANFLTKFADNVTIVHRRDELRAS 180 Query: 181 KIMQDRVRENSKVAWALNRTPLEVAIGDTGVKGLKVRNNETGAEELVEADGVFVAIGHTP 240 KIMQDR REN K++W LNRTP+EV V GLKV NNETG EE++E DG+FVAIGH P Sbjct: 181 KIMQDRARENQKISWKLNRTPVEVLSESDKVTGLKVLNNETGEEEVLETDGIFVAIGHRP 240 Query: 241 NTAFLGGQITTDANGYIVVNPGTTETNIPGVFACGDVQDTRYRQAISAAGTGCMAAMDAE 300 NT FLG QI D +GYI V PGTTETNI GVFACGDVQD RYRQAI+AAGTGCMAA+DAE Sbjct: 241 NTGFLGSQIDLDESGYITVKPGTTETNIKGVFACGDVQDKRYRQAITAAGTGCMAALDAE 300 Query: 301 KYLEGSMVHDWSETLDK 317 +YLEG + DWSETL++ Sbjct: 301 RYLEGDAILDWSETLNQ 317 >B1D8P9.1 B1D8P9_9BACL Thioredoxin reductase EC=1.8.1.9 Length = 313 Score = 498 bits (1283), Expect = e-139, Method: Compositional matrix adjust. Identities = 230/310 (74%), Positives = 272/310 (87%), Gaps = 1/310 (0%) Query: 1 MYKTIVIGTGPAGLTAAIYLARANLSPLVIEGLQPGGQLXXXXEVENFPGFPDGILGPDL 60 MYKT++IGTGPAGLTAAIYLARAN+ PLVIEG QPGGQL E+ENFPGFP+GILG +L Sbjct: 1 MYKTVIIGTGPAGLTAAIYLARANMEPLVIEGWQPGGQLTTTTEIENFPGFPEGILGSEL 60 Query: 61 MDNMRKQAERFGAQFKNGWVEAVDFSQRPFKITVDGLGVLEAETVIISTGASARYLGIPG 120 M NMRKQA+RFGA F+NG V++VDFS+RP+ + V+G+G ++AE+VI+STGASA+YLGIPG Sbjct: 61 MSNMRKQAQRFGASFRNGSVKSVDFSKRPYTLDVEGIGEIQAESVILSTGASAKYLGIPG 120 Query: 121 EQDNVGRGVSTCATCDGFFFRGKKIVVVGGGDSAMEEASFLTRFASSVTLVHRRSELRAS 180 EQ+N+GRGVSTCATCDGFFFR KK+++VGGGDSAMEEA FLTRFAS VT+V+RR ELRAS Sbjct: 121 EQENIGRGVSTCATCDGFFFRNKKLIIVGGGDSAMEEAVFLTRFASEVTVVNRREELRAS 180 Query: 181 KIMQDRVRENSKVAWALNRTPLEVAIGDTGVKGLKVRNNETGAEELVEADGVFVAIGHTP 240 KIMQDR R N K++W LN+TPLEV G+ G+KGLKVRNN TG EE VEADGVF+ IGHTP Sbjct: 181 KIMQDRARANEKISWNLNKTPLEVVPGEMGLKGLKVRNNATGEEEFVEADGVFITIGHTP 240 Query: 241 NTAFLGGQITTDANGYIVVNPGTTETNIPGVFACGDVQDTRYRQAISAAGTGCMAAMDAE 300 NT FL GQI TD GYI+V PGT+ETNIPGVFACGDVQD +YRQAI+AAG+GCMAA+DAE Sbjct: 241 NTKFLSGQIDTDEQGYIIVKPGTSETNIPGVFACGDVQDRQYRQAITAAGSGCMAALDAE 300 Query: 301 KYLEGSMVHD 310 ++LE + HD Sbjct: 301 RFLE-AQSHD 309 >C2VZH1.1 C2VZH1_BACCE Thioredoxin-disulfide reductase Length = 314 Score = 494 bits (1271), Expect = e-138, Method: Compositional matrix adjust. Identities = 232/315 (73%), Positives = 275/315 (87%), Gaps = 1/315 (0%) Query: 1 MYKTIVIGTGPAGLTAAIYLARANLSPLVIEGLQPGGQLXXXXEVENFPGFPDGILGPDL 60 M+K +++GTGPAGLTAAIYLARAN++PL+IEG QPGGQL EVENFPGFPDGI+GPDL Sbjct: 1 MHKVVILGTGPAGLTAAIYLARANMNPLIIEGTQPGGQLTTTTEVENFPGFPDGIMGPDL 60 Query: 61 MDNMRKQAERFGAQFKNGWVEAVDFSQRPFKITVDGLGVLEAETVIISTGASARYLGIPG 120 MDNMRKQAERFGA+FKNGWVE VD S+RPFKITV G+G +EAE +I+STGASA+ LGIPG Sbjct: 61 MDNMRKQAERFGAEFKNGWVERVDVSKRPFKITVTGMGEIEAEAIIVSTGASAKLLGIPG 120 Query: 121 EQDNVGRGVSTCATCDGFFFRGKKIVVVGGGDSAMEEASFLTRFASSVTLVHRRSELRAS 180 E+DN+GRGV TCATCDGFF+RGKK++VVGGGDSAMEEA+FLT+FA+ V +VHRR ELRAS Sbjct: 121 EKDNMGRGVGTCATCDGFFYRGKKVIVVGGGDSAMEEANFLTKFATEVHIVHRRDELRAS 180 Query: 181 KIMQDRVRENSKVAWALNRTPLEVAIGDTGVKGLKVRNNETGAEELVEADGVFVAIGHTP 240 KIMQDR + N K+ W LN+TP+EV + D V GLKV++NETG EE++E DG+F+AIGH P Sbjct: 181 KIMQDRAKANEKITWGLNKTPIEV-LADGKVTGLKVKDNETGEEEIIETDGIFIAIGHRP 239 Query: 241 NTAFLGGQITTDANGYIVVNPGTTETNIPGVFACGDVQDTRYRQAISAAGTGCMAAMDAE 300 NT FL GQ+ D GYIVV PGTTETNIPGVFACGDVQD RYRQAI+AAGTGCMAA+D+E Sbjct: 240 NTEFLNGQVEIDEAGYIVVKPGTTETNIPGVFACGDVQDHRYRQAITAAGTGCMAALDSE 299 Query: 301 KYLEGSMVHDWSETL 315 ++LE VHDWS++L Sbjct: 300 RFLENHAVHDWSQSL 314 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,915,696,396 Number of extensions: 80761341 Number of successful extensions: 290030 Number of sequences better than 1.0e-05: 4851 Number of HSP's gapped: 282274 Number of HSP's successfully gapped: 4856 Length of query: 317 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 182 Effective length of database: 1,788,859,178 Effective search space: 325572370396 Effective search space used: 325572370396 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)