BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0012.0018.p (316 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K379.1 B3K379_9BACI Glucokinase, ROK family 528 e-148 B1DKY0.1 B1DKY0_9BACL Glucokinase, ROK family 413 e-113 C5D4B9.1 C5D4B9_9BACI Glucokinase, ROK family 242 3e-62 C2YWK1.1 C2YWK1_BACCE Glucokinase 237 1e-60 B0QJ85.1 B0QJ85_BACAN Glucokinase EC=2.7.1.2 237 1e-60 >B3K379.1 B3K379_9BACI Glucokinase, ROK family Length = 316 Score = 528 bits (1360), Expect = e-148, Method: Compositional matrix adjust. Identities = 264/316 (83%), Positives = 280/316 (88%) Query: 1 MSESIYVGVDLGGTTIKVGICNAEGNLLHTYEGPTGTADGVDAVIDNIEKYVRQIVEDSP 60 MSE+IYVGVDLGGT IKVGICN EG+LL YEGPT TA GVD VIDNIEKYVR IVE+SP Sbjct: 1 MSENIYVGVDLGGTAIKVGICNEEGHLLQKYEGPTETAKGVDTVIDNIEKYVRHIVEESP 60 Query: 61 YSWDQLAGVGAGLAGFTNIREGIIILAPNIGFRDVPIRSILEGRLNKPVKIDNDANVAAL 120 YSWDQLAGVGAG AGFTNIREGIIILAPN+GF+DVPIR++LE RL KPVKIDNDANVAAL Sbjct: 61 YSWDQLAGVGAGFAGFTNIREGIIILAPNVGFKDVPIRALLEERLGKPVKIDNDANVAAL 120 Query: 121 GEAWSGAGRGVENCVCYTLXXXXXXXXXXXXKVYQGFAGLAGELGHISVVPDLEAIQCGC 180 GEAWSGAGRGVENCVCYTL K+YQGF G+AGELGHISVVPDLEAIQCGC Sbjct: 121 GEAWSGAGRGVENCVCYTLGTGVGGGIIVNGKIYQGFGGMAGELGHISVVPDLEAIQCGC 180 Query: 181 GNMGCLETVSSATGIIRMANDAVSRGDRTSLSMVEKIAAKEVFDAAKAGDEVALRIVNRA 240 G MGCLETVSSATGIIRMA DAV RGDRTSL+ VE IAAKEVFDAAKAGDEVA+RIVNRA Sbjct: 181 GEMGCLETVSSATGIIRMAKDAVERGDRTSLAHVESIAAKEVFDAAKAGDEVAIRIVNRA 240 Query: 241 AFYLGKSMAAVAAVLNPEVFIVGGGVSKAGDILFDEVRRVFAKLAPAPLQTGVTIVPAEL 300 A+YLGKSMAAVAAVLNPE FI+GGGVSKAGDILF+EVR VFAKL P PLQ GV IVPAEL Sbjct: 241 AYYLGKSMAAVAAVLNPEAFIIGGGVSKAGDILFNEVRAVFAKLTPEPLQRGVRIVPAEL 300 Query: 301 GNDAGIIGAAGLLLRS 316 GNDAG++GAAGL LRS Sbjct: 301 GNDAGVVGAAGLHLRS 316 >B1DKY0.1 B1DKY0_9BACL Glucokinase, ROK family Length = 316 Score = 413 bits (1062), Expect = e-113, Method: Compositional matrix adjust. Identities = 204/316 (64%), Positives = 244/316 (77%) Query: 1 MSESIYVGVDLGGTTIKVGICNAEGNLLHTYEGPTGTADGVDAVIDNIEKYVRQIVEDSP 60 MSE IYVGVD+GGT IKVGICN EG LLHTYEGPT T+ G D ++ NI +Y R IV +SP Sbjct: 1 MSEKIYVGVDVGGTAIKVGICNVEGELLHTYEGPTETSKGTDTILHNIAQYARNIVTESP 60 Query: 61 YSWDQLAGVGAGLAGFTNIREGIIILAPNIGFRDVPIRSILEGRLNKPVKIDNDANVAAL 120 + W+Q+ GVG G+AGF +I GI+ + N+ +V ++ LE L V ++NDANVAAL Sbjct: 61 FDWEQVEGVGVGIAGFLDIPNGIVKFSGNLKIENVHLKEYLEEELQVKVLVNNDANVAAL 120 Query: 121 GEAWSGAGRGVENCVCYTLXXXXXXXXXXXXKVYQGFAGLAGELGHISVVPDLEAIQCGC 180 GEAW+GAG+G++NCVCYTL K+ +GFAG+AGELGHI++VPDLEAIQCGC Sbjct: 121 GEAWAGAGKGIDNCVCYTLGTGVGGGIIIGGKIVEGFAGMAGELGHIAIVPDLEAIQCGC 180 Query: 181 GNMGCLETVSSATGIIRMANDAVSRGDRTSLSMVEKIAAKEVFDAAKAGDEVALRIVNRA 240 G MGCLE+VSSATGIIRMA DAV RGDRT LS VE I AK+V DAAKAGDEVA RIV+RA Sbjct: 181 GKMGCLESVSSATGIIRMAKDAVERGDRTVLSTVEDIMAKDVIDAAKAGDEVASRIVSRA 240 Query: 241 AFYLGKSMAAVAAVLNPEVFIVGGGVSKAGDILFDEVRRVFAKLAPAPLQTGVTIVPAEL 300 A+YLGKSMA +A VLNPE FI+GGGVSKAGD LFD++R VF K Q GV IV A L Sbjct: 241 AYYLGKSMALMAVVLNPECFIIGGGVSKAGDFLFDQIREVFEKYTQKEAQEGVKIVAATL 300 Query: 301 GNDAGIIGAAGLLLRS 316 GN+AG++GAAGL+LRS Sbjct: 301 GNNAGVVGAAGLILRS 316 >C5D4B9.1 C5D4B9_9BACI Glucokinase, ROK family Length = 318 Score = 242 bits (618), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 128/312 (41%), Positives = 191/312 (61%), Gaps = 1/312 (0%) Query: 1 MSESIYVGVDLGGTTIKVGICNAEGNLLHTYEGPTGTADGVDAVIDNIEKYVRQIVEDSP 60 M+E VGVDLGGTT K+ +G+++H +E T ++ + ++ +I + + + + Sbjct: 1 MTEKWLVGVDLGGTTTKMAFVTTDGDIVHKWEIDTDISNKGENIVKHISQSLEETLHHLG 60 Query: 61 YSWDQLAGVGAGLAGFTNIREGIIILAPNIGFRDVPIRSILEGRLNKPVKIDNDANVAAL 120 S D+L +G G G ++ G++ A N+G+++ P++ LE + PV +DNDAN+AAL Sbjct: 61 ESKDRLLAIGIGAPGPVHMETGMLYEAVNLGWKNYPLKDRLERETSLPVAVDNDANIAAL 120 Query: 121 GEAWSGAGRGVENCVCYTLXXXXXXXXXXXXKVYQGFAGLAGELGHISVVPDLEAIQCGC 180 GE W GAG G + +C TL ++ G G GE+GH++++P A C C Sbjct: 121 GEMWKGAGSGARDLICVTLGTGVGGGVIANGQIVHGVNGAGGEIGHMTMLPKGGA-PCNC 179 Query: 181 GNMGCLETVSSATGIIRMANDAVSRGDRTSLSMVEKIAAKEVFDAAKAGDEVALRIVNRA 240 G GCLET++SATGI+R+A + +S D+ +L E + AK VFDAA+A DE+AL +V+ Sbjct: 180 GKTGCLETIASATGIVRIAKEKLSHWDKPTLLRDETVTAKAVFDAARANDELALEVVDEV 239 Query: 241 AFYLGKSMAAVAAVLNPEVFIVGGGVSKAGDILFDEVRRVFAKLAPAPLQTGVTIVPAEL 300 FYLG ++A A V NPE ++GGGVSKAG+IL + V F + A + G TIV A L Sbjct: 240 MFYLGLALANAANVSNPEKIVIGGGVSKAGNILVERVSTYFRRFAFPRVAEGATIVLATL 299 Query: 301 GNDAGIIGAAGL 312 GNDAG+IG A L Sbjct: 300 GNDAGVIGGAWL 311 >C2YWK1.1 C2YWK1_BACCE Glucokinase Length = 327 Score = 237 bits (605), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 133/321 (41%), Positives = 194/321 (60%), Gaps = 6/321 (1%) Query: 1 MSESIYVGVDLGGTTIKVGICNAEGNLLHTYEGPTGTADGVDAVIDNIEKYVRQIVEDSP 60 M E VGVDLGGTTIK+ N G +LH +E PT T + + ++ K + + +E+ Sbjct: 1 MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELG 60 Query: 61 YSWDQLAGVGAGLAGFTNIREGIIILAPNIGFRDVPIRSILEGRLNKPVKIDNDANVAAL 120 +L G+G G G ++ G+I A N+G+++ P+R +LE PV IDNDAN+AAL Sbjct: 61 ELKSKLIGIGMGAPGPVHVASGMIYEAVNLGWKNYPLRDLLEVETGLPVVIDNDANLAAL 120 Query: 121 GEAWSGAGRGVENCVCYTLXXXXXXXXXXXXKVYQGFAGLAGELGHISVVPDLEAIQCGC 180 GE W GAG G ++ +C TL ++ G +G AGE+GHI+VV + A C C Sbjct: 121 GEMWKGAGEGAKDLICMTLGTGVGGGVIANGEIVHGVSGAAGEIGHITVVTE-NAFPCNC 179 Query: 181 GNMGCLETVSSATGIIRMANDAVSRGDRTSL--SMVE---KIAAKEVFDAAKAGDEVALR 235 G GCLETV+SATGI+R+A + D+ S+ SM+ +I +K+VF+A GDE+A Sbjct: 180 GKSGCLETVASATGIVRVAMQKIQETDKESMLRSMLAEEGRITSKDVFEALGQGDELASE 239 Query: 236 IVNRAAFYLGKSMAAVAAVLNPEVFIVGGGVSKAGDILFDEVRRVFAKLAPAPLQTGVTI 295 +V + A YLG ++A +A+ LNPE ++GGGVSKAGD L + ++R F + A + + Sbjct: 240 VVEKVASYLGLAVANLASTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKL 299 Query: 296 VPAELGNDAGIIGAAGLLLRS 316 A LGNDAG+IG A L+ + Sbjct: 300 AIAILGNDAGVIGGAWLVKKH 320 >B0QJ85.1 B0QJ85_BACAN Glucokinase EC=2.7.1.2 Length = 327 Score = 237 bits (604), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 132/321 (41%), Positives = 194/321 (60%), Gaps = 6/321 (1%) Query: 1 MSESIYVGVDLGGTTIKVGICNAEGNLLHTYEGPTGTADGVDAVIDNIEKYVRQIVEDSP 60 M E VGVDLGGTTIK+ N G +LH +E PT T + + ++ K + + +E+ Sbjct: 1 MEEKWLVGVDLGGTTIKLAFINVYGEILHKWEIPTNTNEQGKHITLDVAKAIDKKLEELG 60 Query: 61 YSWDQLAGVGAGLAGFTNIREGIIILAPNIGFRDVPIRSILEGRLNKPVKIDNDANVAAL 120 +L G+G G G ++ G+I A N+G+++ P++ +LE PV IDNDAN+AAL Sbjct: 61 ELKSKLIGIGMGAPGPVHVASGMIYEAVNLGWKNYPLKDLLEVETGLPVVIDNDANLAAL 120 Query: 121 GEAWSGAGRGVENCVCYTLXXXXXXXXXXXXKVYQGFAGLAGELGHISVVPDLEAIQCGC 180 GE W GAG G +N +C TL ++ G +G AGE+GHI+VV + A C C Sbjct: 121 GEMWKGAGEGAKNLICMTLGTGVGGGVIANGEIVHGVSGAAGEIGHITVVTE-NAFPCNC 179 Query: 181 GNMGCLETVSSATGIIRMANDAVSRGDRTSL--SMVE---KIAAKEVFDAAKAGDEVALR 235 G GCLETV+SATGI+R+A + D+ S+ SM+ +I +K+VF+A GDE+A Sbjct: 180 GKSGCLETVASATGIVRVAMQKIQETDKESILRSMLAEEGRITSKDVFEAHGQGDELAGE 239 Query: 236 IVNRAAFYLGKSMAAVAAVLNPEVFIVGGGVSKAGDILFDEVRRVFAKLAPAPLQTGVTI 295 +V + A YLG ++A +++ LNPE ++GGGVSKAGD L + ++R F + A + + Sbjct: 240 VVEKVASYLGLAVANLSSTLNPEKIVIGGGVSKAGDALLEPIQRYFEQYAFSRAVKSTKL 299 Query: 296 VPAELGNDAGIIGAAGLLLRS 316 A LGNDAG+IG A L+ + Sbjct: 300 AIATLGNDAGVIGGAWLVKKH 320 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.138 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,825,119,584 Number of extensions: 74731582 Number of successful extensions: 214003 Number of sequences better than 1.0e-05: 3661 Number of HSP's gapped: 205222 Number of HSP's successfully gapped: 3669 Length of query: 316 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 181 Effective length of database: 1,788,859,178 Effective search space: 323783511218 Effective search space used: 323783511218 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)