BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0014.p (209 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K3F2.1 B3K3F2_9BACI Regulatory protein TetR 179 1e-43 B4V497.1 B4V497_9ACTO TetR-family transcriptional regulator 156 1e-36 A4FEV2.1 A4FEV2_SACEN TetR-family transcriptional regulator 149 1e-34 C4DPI6.1 C4DPI6_9ACTO Transcriptional regulator, TetR family 137 8e-31 B2IZK3.1 B2IZK3_NOSP7 Transcriptional regulator, TetR family 135 3e-30 >B3K3F2.1 B3K3F2_9BACI Regulatory protein TetR Length = 197 Score = 179 bits (454), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 90/174 (51%), Positives = 121/174 (69%), Gaps = 2/174 (1%) Query: 16 LSKTEIMDAAEQTLRRFGPDKTSVTDVAKLLGVSHGTLYRHFPSKAALREAVTERWLEEQ 75 L+K I+DAAEQTLRR+GPDKTSV DVAK L VSHG+LYRHFPSKAALREAVTERWL ++ Sbjct: 7 LTKEAILDAAEQTLRRYGPDKTSVVDVAKALQVSHGSLYRHFPSKAALREAVTERWL-QR 65 Query: 76 IVVPLEQIVKAPADNALAQLKVYIARLIELKRHYAEQDREMFKMYTDVTMEAAELIEVHI 135 I PL+ I +A +L+++ LI KR Y +D EMF MY VT+EA ++I+ H+ Sbjct: 66 IADPLQIIADGTDGSATDRLRLWTDTLIRAKRTYVLEDPEMFAMYASVTLEAVKIIDTHV 125 Query: 136 QRIMEQMGILIDRGIQQKRIAQSAATSSLARSLFHATSRFHHPVHAHEWRSASI 189 ++ Q+ ++D+G++ Q S+ A++ F ATS FHHP HA++W S I Sbjct: 126 NLLIGQITQIMDQGMRAGEFKQGRPESA-AKAFFMATSLFHHPAHAYQWTSDGI 178 >B4V497.1 B4V497_9ACTO TetR-family transcriptional regulator Length = 197 Score = 156 bits (395), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 77/174 (44%), Positives = 114/174 (65%), Gaps = 2/174 (1%) Query: 16 LSKTEIMDAAEQTLRRFGPDKTSVTDVAKLLGVSHGTLYRHFPSKAALREAVTERWLEEQ 75 L+ I++ E+ LRRFGP K +V DVA+ LGVSHG++YRHFPSKAALREAVTERWL + Sbjct: 9 LTPERILETTEEVLRRFGPAKATVVDVARALGVSHGSVYRHFPSKAALREAVTERWLTKS 68 Query: 76 IVVPLEQIVKAPADNALAQLKVYIARLIELKRHYAEQDREMFKMYTDVTMEAAELIEVHI 135 +VV LE+I AP A ++L+ ++ L E KR A D E+F YT + E + +++ H+ Sbjct: 69 VVV-LEEIASAPGGTAPSKLESWLEALFEAKRRKAGADPELFATYTVLLAENSGVVDQHL 127 Query: 136 QRIMEQMGILIDRGIQQKRIAQSAATSSLARSLFHATSRFHHPVHAHEWRSASI 189 +++Q+ +I G+ +A ++ AR++F AT RFH P +A +W S +I Sbjct: 128 SELIDQLARIIADGVAAGSLAAPDVPAA-ARAVFDATGRFHDPQYAADWLSPTI 180 >A4FEV2.1 A4FEV2_SACEN TetR-family transcriptional regulator Length = 197 Score = 149 bits (377), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 77/174 (44%), Positives = 114/174 (65%), Gaps = 3/174 (1%) Query: 16 LSKTEIMDAAEQTLRRFGPDKTSVTDVAKLLGVSHGTLYRHFPSKAALREAVTERWLEEQ 75 L+ I+DAAE+TLRRFGP KT+V DVA+ LGVSHG++YRHFPSKAALR+AV ERWL + Sbjct: 6 LTPARILDAAEETLRRFGPAKTTVVDVARALGVSHGSVYRHFPSKAALRDAVAERWL-RR 64 Query: 76 IVVPLEQIVKAPADNALAQLKVYIARLIELKRHYAEQDREMFKMYTDVTMEAAELIEVHI 135 + PLE+ + D A +L+ ++ L K+ A +D E+F Y + +E+ ++I H+ Sbjct: 65 VSAPLEEF-RDGDDTAARRLRDWLLALSGTKQRMAREDPELFATYHAIVVESRDVIGAHL 123 Query: 136 QRIMEQMGILIDRGIQQKRIAQSAATSSLARSLFHATSRFHHPVHAHEWRSASI 189 + EQ+ +I G+ + A S+ AR++ AT+RFH+PVHA EW ++ Sbjct: 124 GVLAEQLEAIIGAGVARGEFAAEDPKSA-ARAVLTATARFHNPVHASEWDDPAL 176 >C4DPI6.1 C4DPI6_9ACTO Transcriptional regulator, TetR family Length = 196 Score = 137 bits (344), Expect = 8e-31, Method: Compositional matrix adjust. Identities = 75/174 (43%), Positives = 106/174 (60%), Gaps = 3/174 (1%) Query: 11 KSSSFLSKTEIMDAAEQTLRRFGPDKTSVTDVAKLLGVSHGTLYRHFPSKAALREAVTER 70 K S L+ I++AAE LRRFGPDKT+V DVA+ LGVSHG++YRHFPSK ALR+AV ER Sbjct: 2 KPSGPLTSDRILEAAEDVLRRFGPDKTTVVDVARQLGVSHGSVYRHFPSKVALRDAVAER 61 Query: 71 WLEEQIVVPLEQIVKAPADNALAQLKVYIARLIELKRHYAEQDREMFKMYTDVTMEAAEL 130 WL ++I PL I A + A +L+ ++ RL KR A D E+F Y +T E+ + Sbjct: 62 WL-DRISRPLADIA-ARSGPAADRLREWMLRLATAKRELAGSDPELFATYFRLTSESRGV 119 Query: 131 IEVHIQRIMEQMGILIDRGIQQKRIAQSAATSSLARSLFHATSRFHHPVHAHEW 184 H + + Q+ +I G++ S ++F A++RF+HP+HA EW Sbjct: 120 GAAHEEHLARQLSGIIADGVRAGEFTVDDPERS-GWAVFRASARFNHPLHAAEW 172 >B2IZK3.1 B2IZK3_NOSP7 Transcriptional regulator, TetR family Length = 195 Score = 135 bits (339), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 71/178 (39%), Positives = 109/178 (61%), Gaps = 3/178 (1%) Query: 12 SSSFLSKTEIMDAAEQTLRRFGPDKTSVTDVAKLLGVSHGTLYRHFPSKAALREAVTERW 71 + S L+ I+DAAE+ L R+G K +V DVA+ L VSHGT+YRHFPSKAALR+AV ERW Sbjct: 2 NDSPLTPERILDAAEEVLCRYGLAKATVVDVARFLEVSHGTIYRHFPSKAALRDAVAERW 61 Query: 72 LEEQIVVPLEQIVKAPADNALAQLKVYIARLIELKRHYAEQDREMFKMYTDVTMEAAELI 131 L ++ +PL I + +A+ QL + +L+ +KR + E+F Y+ + EA ++ Sbjct: 62 L-HRVSIPLAAIAEEQG-SAVEQLHRWFEQLMIMKRQKVLDEPELFATYSAIAQEARGVV 119 Query: 132 EVHIQRIMEQMGILIDRGIQQKRIAQSAATSSLARSLFHATSRFHHPVHAHEWRSASI 189 + HI ++ Q+ +++ GI + ++ A+++F AT RFHHP HA EW I Sbjct: 120 QAHIVELVNQVAAIVESGISSNEFRVTDPQAA-AKAVFQATVRFHHPAHASEWSDPDI 176 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.129 0.358 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 951,938,366 Number of extensions: 32149693 Number of successful extensions: 128074 Number of sequences better than 1.0e-05: 143 Number of HSP's gapped: 128547 Number of HSP's successfully gapped: 143 Length of query: 209 Length of database: 3,060,696,203 Length adjustment: 130 Effective length of query: 79 Effective length of database: 1,835,964,253 Effective search space: 145041175987 Effective search space used: 145041175987 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 128 (53.9 bits)