BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0010.p (583 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K384.1 B3K384_9BACI ABC transporter related 693 0.0 Q4MHS3.1 Q4MHS3_BACCE Multidrug resistance ABC transporter ATP-b... 633 e-179 C3C156.1 C3C156_BACTU ABC transporter 633 e-179 C3E2A5.1 C3E2A5_BACTU ABC transporter 632 e-179 A9VQS1.1 A9VQS1_BACWK ABC transporter related 632 e-179 >B3K384.1 B3K384_9BACI ABC transporter related Length = 598 Score = 693 bits (1789), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/548 (63%), Positives = 409/548 (74%) Query: 1 MISTLVGLVIPMFTKNLVDGFSLASVSKLQXXXXXXXXXXXXXXXXVSIYLLNYVGQKAV 60 +ISTLVGLVIPMFTK+LVDGFSL +++ VSI+LL+Y GQK V Sbjct: 49 VISTLVGLVIPMFTKSLVDGFSLTDMNRSHIIGLGIAFVVQTIAAGVSIFLLSYTGQKMV 108 Query: 61 AGLRDRLWRKFLVLPVAYYNDNRTGESVSRMTNDTGIIKTLISEHLASLFTGVISIVGSI 120 A LR+RLW+K LVLP+ Y++ NR+GESVSRMTNDTG+IK+LIS+H+A F+G+ISIVGSI Sbjct: 109 AALRERLWKKLLVLPIRYFDHNRSGESVSRMTNDTGVIKSLISDHVAGFFSGIISIVGSI 168 Query: 121 AVLLYLNWQMTLVLFTVLPLSALILVPLGRQMYKISKGTQDETASFTATLSGVLSEIRLV 180 VLLYLNW+MTL +F V+P++ALILVPLGR+MYKIS G QDETASFTA +S VLSEIRLV Sbjct: 169 GVLLYLNWKMTLTMFIVIPIAALILVPLGRKMYKISLGMQDETASFTANISQVLSEIRLV 228 Query: 181 KSSGAEQKEYEAGRTGIMNLLSFGIREGKISAMISPXXXXXXXXXXXXXIGYGGMQVSSG 240 K+S AE +EYE G GI NLL+FGI+EG +SA I+P IGYGG+QVS+G Sbjct: 229 KASNAENREYENGNKGITNLLNFGIKEGVVSAWIAPLMSFVLMMLLVVVIGYGGLQVSTG 288 Query: 241 ALTAGELVAFILYLIQIVMPXXXXXXXXXXIQKAKGASERIIETLAADEEIYEGVEEAKS 300 ALTAGELVAFILYLIQIVMP +QKAKGA+ERI+ETL ADEE +E Sbjct: 289 ALTAGELVAFILYLIQIVMPMTQLTTFFTQLQKAKGATERILETLDADEESITAGDEVAD 348 Query: 301 AEEPIVIDDLSFGYTTGDPVLSRVSFSMLPGQVTAIVGPSGGGKTTLFSLLERFYEPQSG 360 A + + I++LSFGY + VL +SF M PG VTA+VGPSGGGKTTLFS+LERFY PQ G Sbjct: 349 ANQRVSIENLSFGYKPDELVLHDISFQMEPGTVTAVVGPSGGGKTTLFSMLERFYLPQKG 408 Query: 361 GIKLGAKPISTFSLRSWRKLIGYVSQESPLLSGTIADNLAYGLNREVGVEELRRAAAMAY 420 I+LG PI TFSLRSWR LIGYVSQESP+++GTI DNL YG++REV ELRRAA MAY Sbjct: 409 QIRLGKTPIDTFSLRSWRGLIGYVSQESPMIAGTIRDNLCYGMDREVSDAELRRAAEMAY 468 Query: 421 ADGFISELPHGYDTDVGERGVKLSXXXXXXXXXXXXXXXDPKILMLDEATASLDSQSEAV 480 ADGFI ELP G+DTDVGERGVKLS DPKILMLDEAT+SLDS+SE Sbjct: 469 ADGFIDELPSGFDTDVGERGVKLSGGQRQRIAIARALLRDPKILMLDEATSSLDSRSEIE 528 Query: 481 VQKALSNLMKGRTTIVIAHRLATVVNADQIIFMEKGRITGRGTXXXXXXXXXXXXXFAEQ 540 VQKAL NLM GRTTI+IAHRL+TVV ADQIIF+EKG +TGRGT FA Q Sbjct: 529 VQKALKNLMAGRTTIIIAHRLSTVVGADQIIFIEKGTVTGRGTHDELIGQHDMYREFAVQ 588 Query: 541 QLQLNSPV 548 QLQ+N + Sbjct: 589 QLQMNEAI 596 >Q4MHS3.1 Q4MHS3_BACCE Multidrug resistance ABC transporter ATP-binding and permease protein Length = 586 Score = 633 bits (1633), Expect = e-179, Method: Compositional matrix adjust. Identities = 318/549 (57%), Positives = 396/549 (72%) Query: 1 MISTLVGLVIPMFTKNLVDGFSLASVSKLQXXXXXXXXXXXXXXXXVSIYLLNYVGQKAV 60 ++ST L IPM TK LVD FSL+S+S Q +SIYLLNY+GQK V Sbjct: 38 LLSTGASLFIPMLTKGLVDNFSLSSISTGQIVGLVAFFIMQTVAAGLSIYLLNYIGQKIV 97 Query: 61 AGLRDRLWRKFLVLPVAYYNDNRTGESVSRMTNDTGIIKTLISEHLASLFTGVISIVGSI 120 AGLR+RLW+K L+LPV+YYN NRTG+++SRMTNDTG++KTLISEHL++L TG ISIVGS+ Sbjct: 98 AGLRERLWKKVLILPVSYYNQNRTGDTISRMTNDTGVVKTLISEHLSNLLTGGISIVGSL 157 Query: 121 AVLLYLNWQMTLVLFTVLPLSALILVPLGRQMYKISKGTQDETASFTATLSGVLSEIRLV 180 VL L+W+MTL+L TV+PLS LILVPLGR+MYKI K QDETASFT+ L+ VLSEIRLV Sbjct: 158 IVLFVLDWKMTLLLLTVIPLSVLILVPLGRKMYKILKALQDETASFTSVLTQVLSEIRLV 217 Query: 181 KSSGAEQKEYEAGRTGIMNLLSFGIREGKISAMISPXXXXXXXXXXXXXIGYGGMQVSSG 240 KSS E++EYE G TGI LL FG++EGK+ A+ISP +GYGGM+VSSG Sbjct: 218 KSSXTEKREYETGNTGIQKLLQFGLKEGKVQALISPVMSFVLMALLVIIVGYGGMRVSSG 277 Query: 241 ALTAGELVAFILYLIQIVMPXXXXXXXXXXIQKAKGASERIIETLAADEEIYEGVEEAKS 300 ALT GELVAFILYL+QI+MP QKA GA+ERI L + E +E + + Sbjct: 278 ALTTGELVAFILYLVQIIMPMSQLSMFFTQFQKAIGATERINTILEYEVEDHETGAKVTN 337 Query: 301 AEEPIVIDDLSFGYTTGDPVLSRVSFSMLPGQVTAIVGPSGGGKTTLFSLLERFYEPQSG 360 A++PIV++++ F Y + VL + F++ G+VTAIVGPSG GKTTLFSLLERFYEP SG Sbjct: 338 AKQPIVLENVHFEYNEEEQVLKNIDFTIESGKVTAIVGPSGSGKTTLFSLLERFYEPTSG 397 Query: 361 GIKLGAKPISTFSLRSWRKLIGYVSQESPLLSGTIADNLAYGLNREVGVEELRRAAAMAY 420 IKLG I+ +SL+SWR+ IGYVSQ+SPL+ GTI DN+ YG+ EV EE+ + AAMAY Sbjct: 398 AIKLGKDSITNYSLQSWRRQIGYVSQDSPLIDGTIRDNICYGVEGEVTDEEIEKVAAMAY 457 Query: 421 ADGFISELPHGYDTDVGERGVKLSXXXXXXXXXXXXXXXDPKILMLDEATASLDSQSEAV 480 D FI +LP+GY T+VGERGVKLS +P+ILMLDEAT+SLDS+SE+V Sbjct: 458 VDAFIHDLPNGYATEVGERGVKLSGGQRQRIAIARALLRNPQILMLDEATSSLDSKSESV 517 Query: 481 VQKALSNLMKGRTTIVIAHRLATVVNADQIIFMEKGRITGRGTXXXXXXXXXXXXXFAEQ 540 VQKAL+NLMKGRTT+VIAHRL+TVV+AD+IIF+EKG +TG GT FA Q Sbjct: 518 VQKALNNLMKGRTTLVIAHRLSTVVDADKIIFIEKGNLTGSGTHDELLRTHDMYREFATQ 577 Query: 541 QLQLNSPVL 549 QL++ L Sbjct: 578 QLKIKEAAL 586 >C3C156.1 C3C156_BACTU ABC transporter Length = 586 Score = 633 bits (1632), Expect = e-179, Method: Compositional matrix adjust. Identities = 317/549 (57%), Positives = 397/549 (72%) Query: 1 MISTLVGLVIPMFTKNLVDGFSLASVSKLQXXXXXXXXXXXXXXXXVSIYLLNYVGQKAV 60 ++ST L IPM TK LVD FSL+S+S Q +SIYLLNY+GQK V Sbjct: 38 LLSTGASLFIPMLTKGLVDNFSLSSISTGQIVGLVAFFIMQTVAAGLSIYLLNYIGQKIV 97 Query: 61 AGLRDRLWRKFLVLPVAYYNDNRTGESVSRMTNDTGIIKTLISEHLASLFTGVISIVGSI 120 AGLR+RLW+K L+LPV+YY+ NRTG+++SRMTNDTG++KTLISEHL++L TG ISIVGS+ Sbjct: 98 AGLRERLWKKVLILPVSYYDQNRTGDTISRMTNDTGVVKTLISEHLSNLLTGGISIVGSL 157 Query: 121 AVLLYLNWQMTLVLFTVLPLSALILVPLGRQMYKISKGTQDETASFTATLSGVLSEIRLV 180 VL L+W+MTL+L TV+PLS LILVPLGR+MYKISK QDETASFT+ L+ VLSEIRLV Sbjct: 158 IVLFVLDWKMTLLLLTVIPLSVLILVPLGRKMYKISKALQDETASFTSVLTQVLSEIRLV 217 Query: 181 KSSGAEQKEYEAGRTGIMNLLSFGIREGKISAMISPXXXXXXXXXXXXXIGYGGMQVSSG 240 KSS E++EYE G TGI LL FG++EGK+ A+ISP +GYGGM+VSSG Sbjct: 218 KSSNTEKREYETGNTGIQKLLQFGLKEGKVQALISPVMSFVLMALLVIIVGYGGMRVSSG 277 Query: 241 ALTAGELVAFILYLIQIVMPXXXXXXXXXXIQKAKGASERIIETLAADEEIYEGVEEAKS 300 ALT GELVAFILYL+QI+MP QKA GA+ERI L + E +E + + Sbjct: 278 ALTTGELVAFILYLVQIIMPMSQLSMFFTQFQKAIGATERINTILEYEVEEHETGAKVTN 337 Query: 301 AEEPIVIDDLSFGYTTGDPVLSRVSFSMLPGQVTAIVGPSGGGKTTLFSLLERFYEPQSG 360 A++PIV++++ F Y + VL + F++ G+VTAIVGPSG GKTTLFSLLERFYEP +G Sbjct: 338 AKQPIVLENVHFEYNEEEQVLKNIDFTIESGKVTAIVGPSGSGKTTLFSLLERFYEPTNG 397 Query: 361 GIKLGAKPISTFSLRSWRKLIGYVSQESPLLSGTIADNLAYGLNREVGVEELRRAAAMAY 420 IKLG I+ +SL+SWR+ IGYVSQ+SPL+ GTI DN+ YG+ EV EE+ + AAMAY Sbjct: 398 AIKLGKDSITNYSLQSWRRQIGYVSQDSPLIDGTIRDNICYGVEGEVTDEEIEKVAAMAY 457 Query: 421 ADGFISELPHGYDTDVGERGVKLSXXXXXXXXXXXXXXXDPKILMLDEATASLDSQSEAV 480 D FI +LP+GY T+VGERGVKLS +P+ILMLDEAT+SLDS+SE+V Sbjct: 458 VDAFIHDLPNGYATEVGERGVKLSGGQRQRIAIARALLRNPQILMLDEATSSLDSKSESV 517 Query: 481 VQKALSNLMKGRTTIVIAHRLATVVNADQIIFMEKGRITGRGTXXXXXXXXXXXXXFAEQ 540 VQKAL+NLMKGRTT+VIAHRL+TVV+AD+IIF+EKG +TG GT FA Q Sbjct: 518 VQKALNNLMKGRTTLVIAHRLSTVVDADKIIFIEKGNLTGSGTHDELLRTHDMYREFATQ 577 Query: 541 QLQLNSPVL 549 QL++ L Sbjct: 578 QLKIKEAAL 586 >C3E2A5.1 C3E2A5_BACTU ABC transporter Length = 586 Score = 632 bits (1631), Expect = e-179, Method: Compositional matrix adjust. Identities = 318/549 (57%), Positives = 398/549 (72%) Query: 1 MISTLVGLVIPMFTKNLVDGFSLASVSKLQXXXXXXXXXXXXXXXXVSIYLLNYVGQKAV 60 ++ST L IPM TK LVD FSL+S+S Q +SIYLLNY+GQK V Sbjct: 38 LLSTGASLFIPMLTKGLVDNFSLSSISAGQIVGLVAFFVMQTIAAGLSIYLLNYIGQKIV 97 Query: 61 AGLRDRLWRKFLVLPVAYYNDNRTGESVSRMTNDTGIIKTLISEHLASLFTGVISIVGSI 120 AGLR+RLW+K L+LPV+YY+ NRTG+++SRMTNDTG++KTLISEHL++L TG ISIVGS+ Sbjct: 98 AGLRERLWKKVLILPVSYYDQNRTGDTISRMTNDTGVVKTLISEHLSNLLTGGISIVGSL 157 Query: 121 AVLLYLNWQMTLVLFTVLPLSALILVPLGRQMYKISKGTQDETASFTATLSGVLSEIRLV 180 VL L+W+MT +L TV+PLS LILVPLGR+MYKISK QDETASFT+ L+ VLSEIRLV Sbjct: 158 IVLFVLDWKMTALLLTVIPLSVLILVPLGRKMYKISKALQDETASFTSVLTQVLSEIRLV 217 Query: 181 KSSGAEQKEYEAGRTGIMNLLSFGIREGKISAMISPXXXXXXXXXXXXXIGYGGMQVSSG 240 KSS E++EYE G TGI LL FG++EGK+ A+ISP +GYGGM+VSSG Sbjct: 218 KSSNTEKREYETGNTGIQKLLQFGLKEGKVQALISPVMSFVLMALLVIIVGYGGMRVSSG 277 Query: 241 ALTAGELVAFILYLIQIVMPXXXXXXXXXXIQKAKGASERIIETLAADEEIYEGVEEAKS 300 ALT GELVAFILYL+QIVMP QKA GA+ERI L + E +E + + Sbjct: 278 ALTTGELVAFILYLVQIVMPMSQLSMFFTQFQKAIGATERISTILEYEVEDHETGVKVTN 337 Query: 301 AEEPIVIDDLSFGYTTGDPVLSRVSFSMLPGQVTAIVGPSGGGKTTLFSLLERFYEPQSG 360 A++PIV++++ F Y + VL + F++ G+VTAIVGPSG GKTTLFSLLERFYEP SG Sbjct: 338 AKQPIVLENVHFEYNEEEQVLKNIDFTIESGKVTAIVGPSGSGKTTLFSLLERFYEPTSG 397 Query: 361 GIKLGAKPISTFSLRSWRKLIGYVSQESPLLSGTIADNLAYGLNREVGVEELRRAAAMAY 420 IKLG + I+++SL+SWR+ IGYVSQ+SPL+ GTI DN+ YG+ EV EE+ + AAMAY Sbjct: 398 AIKLGEESITSYSLQSWRRQIGYVSQDSPLIDGTIRDNICYGVEGEVTDEEIEKVAAMAY 457 Query: 421 ADGFISELPHGYDTDVGERGVKLSXXXXXXXXXXXXXXXDPKILMLDEATASLDSQSEAV 480 D FI +LP+GY T+VGERGVKLS +P+ILMLDEAT+SLDS+SE+V Sbjct: 458 VDAFIHDLPNGYATEVGERGVKLSGGQRQRIAIARALLRNPQILMLDEATSSLDSKSESV 517 Query: 481 VQKALSNLMKGRTTIVIAHRLATVVNADQIIFMEKGRITGRGTXXXXXXXXXXXXXFAEQ 540 VQKAL+NLMKGRTT+VIAHRL+TVV+AD+IIF+EKG +TG GT FA Q Sbjct: 518 VQKALNNLMKGRTTLVIAHRLSTVVDADKIIFIEKGNLTGSGTHDELLQTHDMYREFATQ 577 Query: 541 QLQLNSPVL 549 QL++ L Sbjct: 578 QLKIKEGAL 586 >A9VQS1.1 A9VQS1_BACWK ABC transporter related Length = 586 Score = 632 bits (1630), Expect = e-179, Method: Compositional matrix adjust. Identities = 317/549 (57%), Positives = 397/549 (72%) Query: 1 MISTLVGLVIPMFTKNLVDGFSLASVSKLQXXXXXXXXXXXXXXXXVSIYLLNYVGQKAV 60 ++ST L IPM TK LVD FSL+S+S Q +SIYLLNY+GQK V Sbjct: 38 LLSTGASLFIPMLTKGLVDNFSLSSISTGQIVGLIAFFIIQTIAAGLSIYLLNYIGQKIV 97 Query: 61 AGLRDRLWRKFLVLPVAYYNDNRTGESVSRMTNDTGIIKTLISEHLASLFTGVISIVGSI 120 AGLR+RLW+K L+LPV+YY+ NRTG+++SRMTNDTG++KTLISEHL++L TG ISI+GS+ Sbjct: 98 AGLRERLWKKVLILPVSYYDQNRTGDTISRMTNDTGVVKTLISEHLSNLLTGGISIIGSL 157 Query: 121 AVLLYLNWQMTLVLFTVLPLSALILVPLGRQMYKISKGTQDETASFTATLSGVLSEIRLV 180 VL L+W+MT++L TV+PLS LILVPLGR+MYKISK QDETASFT+ L+ VLSEIRLV Sbjct: 158 IVLFVLDWKMTILLLTVIPLSVLILVPLGRKMYKISKALQDETASFTSVLTQVLSEIRLV 217 Query: 181 KSSGAEQKEYEAGRTGIMNLLSFGIREGKISAMISPXXXXXXXXXXXXXIGYGGMQVSSG 240 KSS E+KEYE G TGI LL FG++EGK+ A+ISP +GYGGM+VSSG Sbjct: 218 KSSNTEKKEYETGNTGIQKLLQFGLKEGKVQALISPVMSFVLMALLVIIVGYGGMRVSSG 277 Query: 241 ALTAGELVAFILYLIQIVMPXXXXXXXXXXIQKAKGASERIIETLAADEEIYEGVEEAKS 300 ALT GELVAFILYL+QI+MP QKA GA+ERI L + E +E + Sbjct: 278 ALTTGELVAFILYLVQIIMPMSQLSMFFTQFQKAIGATERINTILEYEVEDHETGMNVTN 337 Query: 301 AEEPIVIDDLSFGYTTGDPVLSRVSFSMLPGQVTAIVGPSGGGKTTLFSLLERFYEPQSG 360 A++PIVI+++ F Y + +L + F++ G+VTAIVGPSG GKTTLFSLLERFYEP SG Sbjct: 338 AKQPIVIENVHFEYNEEEKILKNIDFTIESGKVTAIVGPSGSGKTTLFSLLERFYEPTSG 397 Query: 361 GIKLGAKPISTFSLRSWRKLIGYVSQESPLLSGTIADNLAYGLNREVGVEELRRAAAMAY 420 IKLG +PI+ +SL+SWR+ IGYVSQ+SPL+ GTI DN+ YG+ EV EE+ + AAMAY Sbjct: 398 FIKLGKEPITAYSLQSWRRQIGYVSQDSPLIDGTIRDNICYGVEGEVTDEEIEKVAAMAY 457 Query: 421 ADGFISELPHGYDTDVGERGVKLSXXXXXXXXXXXXXXXDPKILMLDEATASLDSQSEAV 480 D FI +LP GY T+VGERGVKLS +P+ILMLDEAT+SLDS+SE+V Sbjct: 458 VDAFIHDLPSGYATEVGERGVKLSGGQRQRIAIARALLRNPQILMLDEATSSLDSKSESV 517 Query: 481 VQKALSNLMKGRTTIVIAHRLATVVNADQIIFMEKGRITGRGTXXXXXXXXXXXXXFAEQ 540 VQKAL+NLMKGRTT+VIAHRL+TVV+AD+IIF+EKG +TG G+ FA Q Sbjct: 518 VQKALNNLMKGRTTLVIAHRLSTVVDADKIIFIEKGNLTGSGSHDELLRTHDMYREFAMQ 577 Query: 541 QLQLNSPVL 549 QL++ L Sbjct: 578 QLKIKEGAL 586 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,793,075,076 Number of extensions: 101319490 Number of successful extensions: 573783 Number of sequences better than 1.0e-05: 37183 Number of HSP's gapped: 534458 Number of HSP's successfully gapped: 39564 Length of query: 583 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 442 Effective length of database: 1,732,333,088 Effective search space: 765691224896 Effective search space used: 765691224896 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)