BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0005.0007.p (430 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3EYL7.1 B3EYL7_BACST Two-component response regulator 180 2e-43 B4BMA7.1 B4BMA7_9BACI Two component transcriptional regulator, A... 180 3e-43 A4IPA8.1 A4IPA8_GEOTN Putative uncharacterized protein 179 3e-43 A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, A... 177 2e-42 Q5KYP0.1 Q5KYP0_GEOKA Two-component response regulator 176 3e-42 >B3EYL7.1 B3EYL7_BACST Two-component response regulator Length = 404 Score = 180 bits (457), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 129/429 (30%), Positives = 212/429 (49%), Gaps = 48/429 (11%) Query: 3 KLLIVDDDKWIREGLRANVNWSREGIEVVATAANGEEGWELVQKLRPDILLTDIQMPLLD 62 K+LI DD+ IREG+R +++W+ +EVVA A +GEE EL + R D+L D+ MP++D Sbjct: 5 KVLIADDEAIIREGIRESIDWNEFNMEVVAEAEDGEEALELALRHRVDVLFVDLSMPIMD 64 Query: 63 GLQLAEKVNERYALTKIIFLTGYDDFSYAKKALDLQASGYILKYEDNEVILQSVAGTGNN 122 GL L + E+ +I +TGYD+FSYA++A+ LQ Y+LK D + + + VA Sbjct: 65 GLTLMKYAREKLPNCHMIVITGYDEFSYAQEAIRLQVDDYLLKPTDPQRLREVVAKVKEK 124 Query: 123 XXXXXXXXX-------XXXXSQSLIENKFFADLLSGVPSVDWARREMELLGIQSEGPYFR 175 ++ +F + ++G + + ++ LLG+ P + Sbjct: 125 LEQEQKEKQYRELLTNQVQKHIHVLRQQFGMEWVAGRLTEEDIMGQLSLLGLSRSCPA-Q 183 Query: 176 VAVIQPEDLQRFSRPGIME-NTELLLFSIQNICAELFTSRLPKPFFVPYNHRINIIFNLA 234 V VIQ + ++P + + + +LLLF+I+ +EL K F N I +I Sbjct: 184 VVVIQWFSFK--NQPIVSDRDRQLLLFAIEKAVSELLGDG-EKIVFRDSNEFIVVI---- 236 Query: 235 DTDGASSSGCSLATLLEDIRHTIETCLK----IPVSIGVGTVCEGFGQIPQSYNKALTAA 290 S + E+ +ET LK I S+ + TV G + +Y K Sbjct: 237 ----------SWKPISEEQCRQMETALKQHLHIRASVYIETVEGGMVGVATAYEK----- 281 Query: 291 HMKDVAGRPGLFFCDEXXXXXXXXXXXXKQMESYIHKNYADENLSLAAIAGEIHISPSYV 350 C E ++ YI K+++ +L+L ++A +++SP Y+ Sbjct: 282 -------------CKEQMVEESRLSPIVRRARQYIQKHFSQSDLTLESVAEFLNVSPVYL 328 Query: 351 STLFKKYREINVIEYVIRIRMEKAAELLKQTDCKSYEISEKVGYGNPQYFSVLFKKHFGM 410 S + K+ I+ I + +IRMEKAAELL T+ +EI+E+VGY YFS FKK G+ Sbjct: 329 SRMIKQELGISFIHLLTKIRMEKAAELLLSTELPIHEIAERVGYDTQHYFSTAFKKAMGV 388 Query: 411 SPSDYRKSQ 419 SP+ YR+++ Sbjct: 389 SPNQYRRTR 397 >B4BMA7.1 B4BMA7_9BACI Two component transcriptional regulator, AraC family Length = 400 Score = 180 bits (456), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 132/432 (30%), Positives = 206/432 (47%), Gaps = 54/432 (12%) Query: 1 MLKLLIVDDDKWIREGLRANVNWSREGIEVVATAANGEEGWELVQKLRPDILLTDIQMPL 60 M K+LI DD+ IREG+R +++W++ +EV+A A +GEE EL K +L D+ MP+ Sbjct: 1 MWKVLIADDEMIIREGIRESIDWAQFNMEVIAEAEDGEEALELAIKHEVHVLFVDLSMPI 60 Query: 61 LDGLQLAEKVNERYALTKIIFLTGYDDFSYAKKALDLQASGYILKYEDNEVILQSVAGTG 120 +DGL L + V ER +I +TGYD+FSYA++AL LQ Y+LK D + + + VA Sbjct: 61 MDGLTLMKHVRERLPHCHMIVITGYDEFSYAQEALRLQVDDYLLKPTDPKQLREVVAKVK 120 Query: 121 NNXXXXXXXXXXXXXSQSLIENKFFADLLSGVPSVDWAR---------REMELLGIQSEG 171 S ++ LL V+W R++ LLG+ S Sbjct: 121 EKLEREHQERGYVELLTSQVQKN--VRLLRQQLGVEWVEGRLTEEEMMRQLPLLGLPSFC 178 Query: 172 PYFRVAVIQPEDLQRFSRPGIMENTE--LLLFSIQNICAELFTSRLPKPFFVPYNHRINI 229 P +V VIQ F IM + + +LLF+I+NI +EL NH + + Sbjct: 179 P-VQVVVIQ---WFSFKNQPIMNDRDRHILLFAIENIVSELLV-----------NHEM-L 222 Query: 230 IFNLADTDGASSSGCSLATLLEDIRHTIETCLKIPVSIGVGTVCE----GFGQIPQSYNK 285 +F D++G + E+ R IE LK + IG E G + +Y K Sbjct: 223 VFR--DSNGFVVV-IVWTPISEEQRRGIEAALKQYLYIGASAYMEMVEGGVTGVISAYEK 279 Query: 286 ALTAAHMKDVAGRPGLFFCDEXXXXXXXXXXXXKQMESYIHKNYADENLSLAAIAGEIHI 345 C ++ + YI +++ L+L ++A +++ Sbjct: 280 ------------------CKRKMEEEKRLSPVVRRAKQYIQTHFSQSELTLESVAQFLNV 321 Query: 346 SPSYVSTLFKKYREINVIEYVIRIRMEKAAELLKQTDCKSYEISEKVGYGNPQYFSVLFK 405 SP Y+S + K+ I+ + + +IR+ KA ELL T+ +EI+E+VGY YFS FK Sbjct: 322 SPIYLSRMIKQELGISFVHLLTKIRLTKAVELLLSTELPIHEIAERVGYDTQHYFSTAFK 381 Query: 406 KHFGMSPSDYRK 417 K G+ P+ YRK Sbjct: 382 KAMGVPPNQYRK 393 >A4IPA8.1 A4IPA8_GEOTN Putative uncharacterized protein Length = 400 Score = 179 bits (455), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 132/432 (30%), Positives = 206/432 (47%), Gaps = 54/432 (12%) Query: 1 MLKLLIVDDDKWIREGLRANVNWSREGIEVVATAANGEEGWELVQKLRPDILLTDIQMPL 60 M K+LI DD+ IREG+R +++W++ +EV+A A +GEE EL K +L D+ MP+ Sbjct: 1 MWKVLIADDEMIIREGIRESIDWAQFNMEVIAEAEDGEEALELAIKHEVHVLFVDLSMPI 60 Query: 61 LDGLQLAEKVNERYALTKIIFLTGYDDFSYAKKALDLQASGYILKYEDNEVILQSVAGTG 120 +DGL L + V ER +I +TGYD+FSYA++AL LQ Y+LK D + + + VA Sbjct: 61 MDGLTLMKHVRERLPHCHMIVITGYDEFSYAQEALRLQVDDYLLKPTDPKQLREVVAKVK 120 Query: 121 NNXXXXXXXXXXXXXSQSLIENKFFADLLSGVPSVDWAR---------REMELLGIQSEG 171 S ++ LL V+W R++ LLG+ S Sbjct: 121 EKLEREHQERGYVELLTSQVQKN--VGLLRQQLGVEWVEGRLREEEMMRQLPLLGLPSFC 178 Query: 172 PYFRVAVIQPEDLQRFSRPGIMENTE--LLLFSIQNICAELFTSRLPKPFFVPYNHRINI 229 P +V VIQ F IM + + +LLF+I+NI +EL NH + + Sbjct: 179 P-VQVVVIQ---WFSFKNQPIMNDRDRYILLFAIENIVSELLV-----------NHEM-L 222 Query: 230 IFNLADTDGASSSGCSLATLLEDIRHTIETCLKIPVSIGVGTVCE----GFGQIPQSYNK 285 +F D++G + E+ R IE LK + IG E G + +Y K Sbjct: 223 VFR--DSNGFVVV-IVWTPISEEQRRGIEAALKQYLYIGASAYMEMVEGGVTGVISAYEK 279 Query: 286 ALTAAHMKDVAGRPGLFFCDEXXXXXXXXXXXXKQMESYIHKNYADENLSLAAIAGEIHI 345 C ++ + YI +++ L+L ++A +++ Sbjct: 280 ------------------CKRKMEEEKRLSPVVRRAKQYIQTHFSQSELTLESVAQFLNV 321 Query: 346 SPSYVSTLFKKYREINVIEYVIRIRMEKAAELLKQTDCKSYEISEKVGYGNPQYFSVLFK 405 SP Y+S + K+ I+ + + +IR+ KA ELL T+ +EI+E+VGY YFS FK Sbjct: 322 SPIYLSRMIKQELGISFVHLLTKIRLTKAVELLLSTELPIHEIAERVGYDTQHYFSTAFK 381 Query: 406 KHFGMSPSDYRK 417 K G+ P+ YRK Sbjct: 382 KAMGVPPNQYRK 393 >A9AWB3.1 A9AWB3_HERA2 Two component transcriptional regulator, AraC family Length = 414 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 119/423 (28%), Positives = 199/423 (47%), Gaps = 22/423 (5%) Query: 3 KLLIVDDDKWIREGLRANVNWSREGIEVVATAANGEEGWELVQKLRPDILLTDIQMPLLD 62 K+ +V+D+ REG+R ++W+ G + A++GE L+++ RPDIL+TDI+MP +D Sbjct: 4 KVFLVEDEIIAREGIRDAIDWAAAGYQFCGEASDGEIALPLIRERRPDILITDIKMPFMD 63 Query: 63 GLQLAEKVNERYALTKIIFLTGYDDFSYAKKALDLQASGYILK---YEDNEVILQSVA-- 117 GLQL V E TKII L+G+D+F YA++A+ + + Y+LK +D L+ +A Sbjct: 64 GLQLCRIVKETLPTTKIIILSGHDEFRYAQEAMQIGVTQYLLKPIVAQDLLAALRKIASQ 123 Query: 118 --GTGNNXXXXXXXXXXXXXSQSLIENKFFADLLSGVPSVDWARREMELLGIQSEGPYFR 175 G Q ++ + DL+SG S + L I P+++ Sbjct: 124 IDGERQAKAQLETLQAQMFDHQPMLRERCLLDLVSGSSSAADFMEQARNLEIDLLAPWYQ 183 Query: 176 VAVIQPEDLQRFSRPGIMENTELLLFSI-QNICAELFTSRLPKPFFVPYNHRINIIFNLA 234 V V+ + P L+++ Q + + S P V + H + + Sbjct: 184 VLVMHAMPPSAATAP---------LYTLYQQVDVTVAASLNQSPLVVAFKHGLEDTILIV 234 Query: 235 DTDGASSSGCSLATLLEDIRHTIETCLKIPVSIGVGTVCEGFGQIPQSYNKALTAAHMKD 294 + + L +R + L IG+G E IPQS+ +AL + Sbjct: 235 RGETRADMTQQAERLATAMRQRVAEQLGCRAIIGIGDPTERLSLIPQSFAEALAQISSFE 294 Query: 295 VAGRPGLFFCDEXXXXXXXXXXXXKQMESYIHKNYADENLSLAAIAGEIHISPSYVSTLF 354 RP D + +YI NYAD +SL A + +SP+Y S LF Sbjct: 295 ---RPAE--SDPSDQGQFHGGAIMLKALAYIDTNYADPAMSLGQAAAHVLLSPTYFSALF 349 Query: 355 KKYREINVIEYVIRIRMEKAAELLKQTDCKSYEISEKVGYGNPQYFSVLFKKHFGMSPSD 414 ++ I+Y+ ++R+ KA ELL+ T + EI+ ++GY NP+YF +F+K G P++ Sbjct: 350 RREVGETFIDYLTQVRIRKAIELLRSTSLTASEIAYRIGYQNPRYFYSVFRKVVGQPPNE 409 Query: 415 YRK 417 +R+ Sbjct: 410 FRQ 412 >Q5KYP0.1 Q5KYP0_GEOKA Two-component response regulator Length = 401 Score = 176 bits (447), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 128/429 (29%), Positives = 210/429 (48%), Gaps = 48/429 (11%) Query: 1 MLKLLIVDDDKWIREGLRANVNWSREGIEVVATAANGEEGWELVQKLRPDILLTDIQMPL 60 M K+LI DD+ IREG+R +++W+ +EVVA A +GEE EL + R ++L D+ MP+ Sbjct: 1 MWKVLIADDEAIIREGIRESIDWNEFNMEVVAEAEDGEEALELALRHRVNVLFVDLSMPI 60 Query: 61 LDGLQLAEKVNERYALTKIIFLTGYDDFSYAKKALDLQASGYILKYEDNEVILQSVAGTG 120 +DGL L + E+ +I +TGYD+FSYA++A+ LQ Y+LK D + + + VA Sbjct: 61 MDGLTLMKYAREKLPNCHMIVITGYDEFSYAQEAIRLQVDDYLLKPTDPQRLREVVAKVK 120 Query: 121 NNXXXXXXXXX-------XXXXSQSLIENKFFADLLSGVPSVDWARREMELLGIQSEGPY 173 ++ +F + ++G + + ++ LLG+ P Sbjct: 121 EKLEQEQKEKQYRELLTNQVQKHIHVLRQQFGMEWVAGRLTEEDIMGQLSLLGLSRSCPA 180 Query: 174 FRVAVIQPEDLQRFSRPGIME-NTELLLFSIQNICAELFTSRLPKPFFVPYNHRINIIFN 232 +V VIQ + ++P + + + +LLLF+I+ +EL K F N I +I Sbjct: 181 -QVVVIQWFSFK--NQPIVSDRDRQLLLFAIEKAVSELLGDG-EKIVFRDSNEFIVVI-- 234 Query: 233 LADTDGASSSGCSLATLLEDIRHTIETCLK----IPVSIGVGTVCEGFGQIPQSYNKALT 288 S + E+ +ET LK I S+ + TV G + +Y K Sbjct: 235 ------------SWKPISEEQCRQMETALKQHLHIRASVYIETVEGGMTGVMAAYEK--- 279 Query: 289 AAHMKDVAGRPGLFFCDEXXXXXXXXXXXXKQMESYIHKNYADENLSLAAIAGEIHISPS 348 C E ++ YI K+++ +L+L ++A +++SP Sbjct: 280 ---------------CKEQMVEESRLSPIVRRARQYIQKHFSQSDLTLESVAQFLNVSPV 324 Query: 349 YVSTLFKKYREINVIEYVIRIRMEKAAELLKQTDCKSYEISEKVGYGNPQYFSVLFKKHF 408 Y+S + K+ I+ I + + RMEKAAELL T+ +EI+E+VGY YFS FKK Sbjct: 325 YLSRIIKQELGISFIHLLAKTRMEKAAELLLSTELPIHEIAERVGYDTQHYFSTAFKKAM 384 Query: 409 GMSPSDYRK 417 G+SP+ YR+ Sbjct: 385 GVSPNQYRR 393 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,391,010,637 Number of extensions: 92244223 Number of successful extensions: 267646 Number of sequences better than 1.0e-05: 9715 Number of HSP's gapped: 274640 Number of HSP's successfully gapped: 10363 Length of query: 430 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 291 Effective length of database: 1,751,175,118 Effective search space: 509591959338 Effective search space used: 509591959338 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)